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1-800-PetMeds EXCLUSIVEFlea5X Plus - Generic to Frontline Plus

Starts $38.74 $29.24 
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04-22 lbs
23-44 lbs
45-88 lbs
89-132 lbs
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Flea5X Plus - Generic to Frontline Plus?

Flea5X Plus is a monthly topical flea and tick preventative for dogs and cats over 8 weeks of age. It contains the same active ingredients as Frontline Plus. Flea5X Plus contains fipronil to quickly kill adult fleas, ticks and chewing lice on your pet. Flea5X Plus also contains (S)-methoprene, an insect growth regulator that kills flea eggs and larvae to help end the flea life cycle. In addition to killing adult fleas and preventing reinfestation, Flea5X Plus is effective against ticks such as the brown dog tick, the American dog tick, the lone star tick and the deer tick, including those that may transmit Lyme disease. Choose Flea5X Plus for a great savings over leading comparable brands and get the same effective protection for your pet.

For:

Cats/Kittens over 1.5 lbs (8 weeks or older), Dogs/Puppies over 4 lbs (8 weeks or older)

Benefits:
  • Each application protects your pet from multiple pests for a full month
  • Helps control sarcoptic mange infections in dogs
  • Kills fleas that may cause skin allergies
  • Waterproof formula won't wash off during swimming or bathing
  • Kills fleas, flea eggs, flea larvae, ticks (including those that may transmit Lyme disease and other tickborne diseases), and chewing lice
  • Compare to Frontline Plus, containing the same active ingredients
  • Prevents and controls infestations for 30 days
How it Works:

Flea5X Plus contains fipronil, a slow-acting, broad-spectrum insecticide that disrupts the central nervous system of fleas and ticks. It also contains (S)-Methoprene, an insect growth regulator that helps to stop the flea life cycle by killing flea eggs and larvae. The waterproof formula means your pet will be protected even after swimming or bathing.

Please note: This product is not manufactured or distributed by Merial, the makers of FRONTLINE® Plus. FRONTLINE® is a registered trademark of Merial.

Cautions:

Do not use Flea5X Plus for Dogs on cats. Do not use Flea5X Plus for Cats on dogs. Keep pets away from other treated pets for 24 hours. Contact your veterinarian immediately if Flea5X Plus for Dogs is applied to your cat or ingested by your cat, or if Flea5X Plus for Cats is applied to your dog or ingested by your dog. Your pet may experience some temporary irritation at the site of application. If signs persist or become more severe within a few days of application, consult your veterinarian immediately.

Brand Name:

1-800-PetMeds Flea5X Plus

Generic Name:

fipronil & (S)-methoprene

Active Ingredients:

Fipronil & (S)-methoprene

What is Flea5X Plus used for:

Flea5X Plus kills fleas, ticks, and chewing lice, and controls mites that may cause sarcoptic mange in dogs. It is a long-lasting, fast-acting and waterproof formula containing the same active ingredients as Frontline Plus.

Availability of Flea5X Plus:

Flea5X Plus for Dogs is a non-prescription (OTC) product. Flea5X Plus for Cats is a non-prescription (OTC) product.

How should Flea5X Plus be used:

Use Flea5X Plus for Dogs on dogs and puppies weighing over 4 lbs and 8 weeks of age or older. Use Flea5X Plus for Cats on cats and kittens weighing over 1.5 lbs and 8 weeks of age or older. It is available as 0.50 mL applicators for cats, 0.67 mL applicators for dogs 4-22 lbs, 1.34 mL applicators for dogs 23-44 lbs, 2.68 mL applicators for dogs 45-88 lbs and 4.02 mL applicators for dogs 89-132 lbs. Wait 24 hours for product to dry before allowing your pet to go swimming or bathing your pet. Do not reapply for 30 days.

To apply Flea5X Plus:

Remove tubes from packaging and separate one tube from the rest of the pack. Hold with the notched end pointing up and away from your face. Cut off the end at the notch along the lines. With one hand, spread the fur on your pet's back between the shoulder blades and invert the tube over your pet. Use the open end of the tube to part the fur completely and squeeze the tube firmly to apply all the contents onto that one spot. Wash hands after application.

What are the side effects of Flea5X Plus:

Pets may experience some temporary irritation at the site of product application. If signs persist, consult a veterinarian immediately.

What special precautions are there with Flea5X Plus:

DO NOT USE FLEA5X FOR DOGS ON CATS. DO NOT USE FLEA5X FOR CATS ON DOGS. Do not use on cats or kittens under 1.5 lbs or under 8 weeks of age. Do not use on dogs or puppies under 4 lbs or under 8 weeks of age. Use the entire contents on each pet. Do not split one tube between pets. Do not use multiple tubes on one pet. Weigh your dog to ensure you are applying the right dose formulated for the weight of your dog. Consult your vet before using on debilitated, aged, or medicated pets. Also consult your vet before using on pregnant or nursing dogs. Flea5X Plus for Cats can be used on breeding, pregnant, or lactating cats. Consult a veterinarian before using on pets with known organ dysfunction. Pets may experience temporary irritation at application site. Certain medications can interact with pesticides. Sensitivities may occur after using ANY pesticide product on pets. If signs of sensitivity occur, bathe your pet with soap and rinse with large amounts of water. If signs continue, contact your veterinarian immediately. Do not allow children to apply this product.

Harmful if swallowed. Causes eye irritation. Avoid contact with skin, eyes, or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet.

If swallowed:

Call a poison control center or a doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything by mouth to an unconscious person.

If in eyes:

Flush eyes with plenty of water. Call a doctor if irritation persists.

If on skin:

Wash with plenty of soap and water. Get medical attention if irritation persists.

Hot Line Number:

Have the product container or label with you when calling a poison control center or doctor, or going for treatment. You may also contact 1-866-307-9795 for emergency medical treatment information.

In the event of overdose:

Contact your veterinarian or veterinary emergency room.

How should I store Flea5X Plus:

Keep out of reach of children. Do not remove the tube from the package until you are ready to use it. Store in a cool (below 77°F/25°C) dry place inaccessible to children and pets. Do not refrigerate. Protect from direct sunlight.

How to Use
Directions:
  • Remove the Flea5X Plus product tubes from the package. Separate one tube from the others.
  • Hold the Flea5X Plus tube with notched end pointing up and away from your face and body. Use scissors to cut off the narrow end at the notches along the line.
  • Invert the tube over the back of your pet's neck and use the open end to part your pet's hair.
  • Squeeze the tube firmly to apply all of the solution to your pet's skin, as a spot to your pet's back between the shoulder blades.
  • Do not apply more often than once every 30 days.
Tip:

Wait until application site is fully dry (usually 24 hours) before bathing your pet or letting your pet go swimming.

Dosage:
Dogs/Puppies (8 weeks of age or older):
Weight
Dosage
4 to 22 lbs
Apply contents of 1 applicator once a month (0.67 mL)
23-44 lbs
Apply contents of 1 applicator once a month (1.34 mL)
45-88 lbs
Apply contents of 1 applicator once a month (2.68 mL)
89-132 lbs
Apply contents of 1 applicator once a month (4.02 mL)
Cats/Kittens (8 weeks of age or older):
Weight
Dosage
Over 1.5 lbs
Apply contents of 1 applicator once a month (0.50 mL)
Horses:
Do not use!
Ingredients
Flea5X Plus for Dogs & Puppies 8 weeks or older, 4 to 22 lbs:
Active ingredients (per 0.67 ml applicator)
Amount
Fipronil
9.80%
(S)-methoprene
8.80%
Other ingredients
81.40%
Flea5X Plus for Dogs & Puppies 8 weeks or older, 23-44 lbs:
Active ingredients (per 1.34 ml applicator)
Amount
Fipronil
9.80%
(S)-methoprene
8.80%
Other ingredients
81.40%
Flea5X Plus for Dogs & Puppies 8 weeks or older, 45-88 lbs:
Active ingredients (per 2.68 ml applicator)
Amount
Fipronil
9.80%
(S)-methoprene
8.80%
Other ingredients
81.40%
Flea5X Plus for Dogs & Puppies 8 weeks or older, 89-132 lbs:
Active ingredients (per 4.02 ml applicator)
Amount
Fipronil
9.80%
(S)-methoprene
8.80%
Other ingredients
81.40%
Flea5X Plus for Cats & Kittens 8 weeks or older, over 1.5 lbs:
Active ingredients (per 0.50 ml applicator)
Amount
Fipronil
9.80%
(S)-methoprene
11.80%
Other ingredients
78.40%
Customer Reviews
Flea5X Plus - Generic to Frontline Plus is rated 2.9056 out of 5 by 233.
Rated 1 out of 5 by from Did not work and Smell like butterscotch I have a Shihtzu and unfortunately this product did not work on her. This was the first tiome we tried this product we normally use frontline. Our baby hasnt had fleas all summer but after using this product by the 2nd month she started scratching and we found fleas on her. Also, the butterscotch chemical smell is so strong it took almost a week for the smell to die down. We decided not to finish the medicine and went back to using frontline.
Date published: 2016-11-29
Rated 5 out of 5 by from Worked Great ! The Dog Had Fleas All Summer. I Tried Just About Everything Out There. This Worked ! Thanks !!!
Date published: 2016-11-29
Rated 1 out of 5 by from Bad Smell This product has a very, very, very bad smell to it. I had to give my dog 3 baths to remove the odor. I will never use it again.
Date published: 2016-11-20
Rated 5 out of 5 by from Effective! This product is effective, easy to use and costs less!
Date published: 2016-11-16
Rated 2 out of 5 by from Sudden Failure We have used this brand of flea prevention for our dog for years, and it was always perfectly effective, but in the past two months it has ceased to function. I don't know if it's a bad batch or something, but my dog suddenly got FIVE tick bites in the past six weeks, two of which required vet attention. There is no chance that I simply forgot to apply the medicine - I know for a fact that I did. Just a warning.
Date published: 2016-11-15
Rated 1 out of 5 by from Sorry this did not work for my dog My westie stayed with a sitter, when he came home we had a flea problem. ordered this and it arrived quickly and on time. Unfortunately this product didn't work for him, 24 hours later still no effect. Used a different medication and the results were great.
Date published: 2016-11-14
Rated 5 out of 5 by from No more Fleas!!! I am so very pleased with this product has the same ingredients just doesn't have the front line name put it on my girl no more fleas thank you pet meds you're awesome
Date published: 2016-11-14
Rated 5 out of 5 by from Works great My dog has not had a single flea since I've been using this flea and tick product.
Date published: 2016-11-10
  • 2016-12-06T06:02CST
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Q&A

How long after you give the meds do the fles die?

Asked by: Christina w
Flea5x Plus kills 100% of adult fleas on your pet within 24 hours of application.
Answered by: Carolyn Petmed Pro
Date published: 2016-12-02

What's the difference between the 5x (that i've used for years) and the pricey script oral meds that vet recommends? Thanks. 

Asked by: marcie
The biggest difference is that one product is taking orally so it needs to be monitored and approved by your vet and Flea5X Plus is not. Another difference is that the pills will only do the adult fleas and not the life cycle like the topical.
Answered by: Carolyn Petmed Pro
Date published: 2016-11-15

Does this kill fleas in 12 hours and ticks within 48 hours as frontline does?

Asked by: Ruth
Yes, this contains the same active ingredients as Frontline Plus; therefore, it should work the same to kill fleas and ticks.
Answered by: Christine
Date published: 2016-10-22

Does this protect against mosquitos?

The website claims it protects against mosquitos but this is not indicated anywhere on the box itself.
Asked by: lisalayne
Yes, Flea5X Plus does protect your pet against mosquitoes.
Answered by: Christine
Date published: 2016-10-21

I have two dogs will I need to separate them after application?

Asked by: Frandoon
Yes, it is ideal to separate them if they lick each other or play and may touch the application site.
Answered by: Christine
Date published: 2016-10-19

Is one application of the cat 1.5 lbs enough for a full grown cat weigh aprox 5 lbs it did not seem to work Its almost been 30 days

Asked by: Deb1
Yes, one application should be enough for all cats, regardless of weight. If your cat still has fleas, it may be due to fleas in the environment. Flea5X Plus does not prevent fleas from infecting your cat; it kills fleas after they bite your cat and ingest the medication. Therefore, it is important that you treat the surrounding environment for fleas as well, to prevent new fleas from attaching to your cat.
Answered by: Christine
Date published: 2016-10-18

I'm trying to order the 3pk Frontline for cats, but your message says choose all 3 options???????????

Asked by: LaVonne
You have to choose "All Weights" under cats for Pet's Weight, "3-pack" under supply, and then click add to cart.
Answered by: Christine
Date published: 2016-10-03

How many in a box ? For 30 bucks

Asked by: Sarge 0311
Flea5X Plus comes in three sizes: a 3-pack, a 6-pack, and a 12-pack. The 3-pack is currently $27.89 with our topten coupon.
Answered by: Christine
Date published: 2016-09-30
  • 2016-12-06T06:05CST
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