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Relieves allergy symptoms, insect stings, motion sickness and anxiety in cats & dogs.
 
  • Antihistamine
  • Relieves coughing
  • Sedative
  •  
     

    Diphenhydramine (Generic Benadryl)


     
    Q & A
     
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      Product Info   How to use   Ingredients   Customer Reviews   Q & A  

    What is Diphenhydramine?

    Diphenhydramine is an antihistamine used to relieve allergy symptoms, insect stings, motion sickness, travel anxiety, and other conditions.
     
    For: Cats and Dogs
     
    Benefits:
    Effectively relieves allergy symptoms and itching caused by insect bites
    Can be used as a sedative to treat motion sickness or travel anxiety
    Relieves coughing

    How it works:
    Diphenhydramine comes in 25mg minitabs or 50mg capsules, and is a generic version of Benadryl. As an antihistamine, it counteracts the effect of histamine, which causes symptoms like itching and sneezing.

    Cautions:
    This medication should not be used in pregnant or nursing animals. Do not use the diphenhydramine available in combination with sinus or cold medicines in your pet.

    Diphenhydramine
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      Diphenhydramine 50mg Capsules
      Diphenhydramine 25mg Minitabs

    More Information:
    Brand Name
    Benadryl (Warner Lambert), Histacalm (Virbac)
    Generic Name
    Diphenhydramine (dye-fen-hy¿-dra-meen)

    Manufacturer:
    Various

    What is this medication used for:
    Diphenhydramine is an antihistamine used to relieve allergy symptoms, insect bites or stings and other causes of itching. It is also used for its sedative and antiemetic effects in the treatment of motion sickness and travel anxiety. It is also used for its antitussive effect.

    Availability:
    Diphenhydramine is a non-prescription (OTC) product available as 25mg tablets and 50mg capsules.

    How this medicine should be used:
    Oral diphenhydramine is not FDA-approved for use in veterinary medicine; however, it is a commonly accepted practice to use this medication in dogs and cats. The usual dose in dogs and cats is 0.5-2mg/pound every 8-12 hours. The slow release capsule should not be mixed or dissolved in food. Do not give sinus or cold medicines containing diphenhydramine to your pet.

    What are the side effects:
    Side effects of diphenhydramine include drowsiness, dry mouth and urinary retention. Rarely, vomiting and diarrhea can occur.

    What special precautions are there:
    Do not use this medication in animals that are allergic to it or other antihistamines. Do not use in animals with glaucoma, prostate disease, urinary obstruction, and high blood pressure. Do not use in pregnant or nursing animals. Use with caution when given with other CNS (central nervous system)-depressant drugs such as tranquilizers or barbiturates. Always tell your veterinarian and pharmacist what other medications your pet is taking.

    In the event of an overdose:
    Contact your veterinarian or veterinary emergency room. Symptoms of overdose can include seizures, extreme drowsiness, coma, respiratory depression, and death.

    How should I store this medication:
    Keep this medication in the container it came in, tightly closed. Store this medication at room temperature, away from excess heat, light, and moisture. Do not store in the bathroom. Throw away any medication that is outdated or no longer needed. Keep medication away from children and pets.

    Directions:

    Diphenhydramine is an antihistamine used to relieve allergy symptoms, insect stings, motion sickness, travel anxiety and other conditions.
    It is available over-the-counter (OTC) as 25mg tablets and 50mg capsules.
    Diphenhydramine should not be used in dogs or cats that are pregnant or nursing.
    Tip: The slow release capsule should NOT be mixed or dissolved in food. Do not use sinus or cold medications containing diphenydramine in your pet.
    Dosage:

    Pet Weight Dosage
    Dogs/Cats: All weights Give 0.5 - 2mg per lb of pets body weight every 8 -12 hours
    Horses:

    Storage: Store this medication at room temperature, away from excess heat, light and moisture.

    Diphenhydramine

    Active Ingredients (per Minitab):

    Product Active Ingredients
    Diphenhydramine HCl 25 mg Minitab Diphenhydramine     25 mg
    Other Ingredients (per capsule):
    Corn starch, D&C red #27, Dicalcium Phosphate, Magnesium Stearate, Microcrystalline Cellulose, Polyethylene Glycol, Polyvinyl Alcohol, Silicon Dioxide, Stearic Acid, Talc, Titanium Dioxide.

    Active Ingredients (per capsule):

    Product Active Ingredients
    Diphenhydramine 50 mg Capsules Diphenhydramine Hydrochloride     50 mg
    Other Ingredients (per capsule):
    Colloidal Silicon Dioxide, Croscamellose Sodium, D&C Red #28, FD&C Blue #1, FD&C Red #3, FD&C Red #40, Gelatin, Lactose, Magnesium Stearate. May also contain Polysorbate 80 and iron oxide.
    Diphenhydramine (Generic Benadryl) 4.1 5 53 53
    DIPHENHYDRAMINE product review: One of the oldest antihistamines around(brand name benadryl), this economic generic version, has as much of a chance at providing symptomatic relief, as many of the newer and more expensive antihistamines that have emerged in recent years, in my experience and opinion. I usually will dose this medicine at anywhere between one half to 1 mg per pound once to twice daily for chronic cases. For those frustrating seasonal allergy cases that can often result in endless itching and secondary bacterial skin and ear infections, the mild sedative effect is also helpful in calming dogs down during difficult allergy seasons. It will help to some degree in 25% of cases in my experience, but when I combine its use with an essential omega 3 fatty acid supplement like Super pure Omega 3 or nordic naturals pet cod liver oil, the clinical response rate in terms of symptom relief certainly climbs in my practice. I also like to use at the same time the antioxidant supplement proanthozone as well, whose nonsedative antihistamine effect can also help when used with diphenhydramine. Keeping in mind that many of these allergy cases are due to contact allergens as well, regular shampooing once to twice weekly with the soothing 1800petmeds oatmeal and aloe shampoo can also be helpful in these pets, in addition to diphenhydramine, essential fatty acids and proanthozone. Another wonderful use of diphenhydramine in pets, which also makes it an indispensable part of an animal guardian's pet medicine cabinet, is in those pets prone to sudden allergic reactions such as spider bites or bee stings, especially during the warmer seasons. Animal guardians can often save lots of money on expensive vet visits when a pet comes in from the outside with a swollen muzzle by giving diphenhydramine at a dose of 1 mg per pound every 6-8 hours as needed for the first 24 hours after such an acute reaction. This would also apply for acute vaccination reactions as well. Of course if ever in doubt during these acute sudden reactions, veterinary exam and consultation is always recommended. For more long term skin allergy use, clients need to understand, however that sometimes one type of antihistamine will work in one dog or cat and not in another, so that if there is not adequate improvement with the protocol described here over 10-14 days, I will often try a different antihistamine like chlorphenirimine or clemastine, also available from the 1800petmeds website. My overall rating of this product is a 4. Its ease of use a 5, and efficacy a 3.5, particularly when combined with the other supportive measures described here. 01/13/2009
    This medication is not helpful in my dog's itching, so I have found big relief in Piriton and Zyrtec. 03/04/2015
    For cats, place it far back in throat Giving Benadryl to my dogs has always been easy---just hide it in a spoon of peanut butter, and it's gone down the hatch, easy peasy. But cats don't believe in gulping down a glob of peanut butter, and Benadryl apparently tastes pretty horrendous to a cat. After some trial and error, I have deduced that it is taste-induced nausea which leads to vomiting (and of course the foaming). So I experienced the same thing as many of the other cat owners here when giving Benadryl---the result is lots of foaming and vomiting. I switched to Zyrtec, since it doesn't seem to taste as bad to a cat, but after Zyrtec failed to help with her symptoms, and by this time having had lots of practice pilling my cat, I decided to give Benadryl another try. I have found that I CAN dose my cat with Benadryl without making her sick. The trick is to place the pill far back in the throat. With the cat's head back and the mouth open, drop the pill in---aiming for the back of the throat---while trying to avoid the tongue altogether. If it lands on the tongue (even the back part) rather than in the throat, quickly push the pill back with a finger. Getting it as far back as possible without ever hitting the tongue keeps the cat from being able to eject the pill back up into the mouth, and thus never tastes the pill. Now that I am preventing her from tasting the Benadryl, there has been no more vomiting, no more foaming, and best of all, no more chewiing off her fur and sneezing fits (at least so far). 01/04/2015
    very effective Buster takes one 50mg pill before bed. His sleep cycle had been disturbed but he now sleeps his regular hours and is more active when he wakes up. If I notice his breathing during the day indicates some congestion when the wind is blowing dust and pollen around, one pill relieves it within 30 minutes. His vet has examined him and agrees he has occasional allergies and diphenhydramine is the perfect solution. 12/23/2014
    Not as Effective As I Thought! When I purchased this product, I was hoping for it to be a little more effective. It really hasn't helped with his constant itching, but it stopped my dog from constantly biting on his paws. It does somewhat have a calming effect on him though, and I find that they help him sleep. 11/14/2014
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    134 Questions · 173 Answers

    Ask & Answer.

    Talk to other pet lovers about this product.

     
     
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    my dog is shedding alot of hair he is a mix of terrier/chiuhaha 14lbs and is itching alot wht should i do i usetreeoilskin relief but it does not help
    2 months, 3 weeks ago
    by
    chingee
    west palm
    Answer this question
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    Answers

    Answer: 
    Try Piriton or Zyrtec. I use either on my pug . When she is very itchy I will give her two Piriton at night wrapped in cheese or stuck in one of those little cocktail/Vienna sausages which come in those little tins. Or I will give her one Zyrtec in the day which makes her sleepy, but at least it stops her itching. I will bathe her with Malaseb which helps, but not for long.
    1 month, 1 week ago
    by
    Daisy
    Caribbean
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    Answer: 
    Please consult with your vet in regards to your furry pal's itching problem as it may be allergies and need prescription medication.
    2 months, 3 weeks ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    I will be moving soon, and its a 15 hour drive to our new home, my pom gets very nervous, anxiety, nausea, and just starts drooling/pacing within about 30 minutes of being in the car. Hes done it since hes been a baby and is almost 3 now. Will this help as a sedative to calm these issues even make him a little sleepy for the drive?
    Any tips would be helpful as well!!!
    Thank you!
    5 months, 2 weeks ago
    by
    pomlady0214
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    Answer: 
    Thank you for your question. This product is designed to help stop your pet from itching and scratching. One of the side effects is drowsiness.
    5 months, 1 week ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    8 months ago
    by
    Anonymous
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    Answer: 
    One50mg
    7 months ago
    by
    nance
    irving tx
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    Answer: 
    The recommended dose is 0.5 - 2mg per lb of pets body weight every 8 -12 hours. If your pet weighs
    25 pounds the dose is 12.5mg to 50mg every 8 to 12 hours. The medication may cause drowiness so it is better to start low and work the dose up to the desired effect like giving 1/2 of a 25mg tablet every
    12 hours.
    7 months ago
    by
    Lilli Pharmacist
    Pompano Beach, FL
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    8 months ago
    by
    Anonymous
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    Answer: 
    I use to give Benadryl to my dog and it worked fine but this product is a generic and I've been using it for 2 weeks now and it seems that it's not as efficient.
    7 months ago
    by
    Micky
    Chandler, AZ
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    Answer: 
    Benadryl can help with allergies however the symptoms your cat is experiencing are a concern as there may be a respiratory infection present. Please consult with your veterinarian prior giving the Benadryl in case your pet has an infection.
    8 months ago
    by
    Lilli Pharmacist
    Pompano Beach, FL
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    0
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    My 7 year old 100 lb Lab has seasonal allergies in spring and then in fall which cause him to scratch and irritate his skin. What product and dosage would you recommend?
    8 months ago
    by
    Karie
    Waco Texas
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    Answer: 
    Thank you for your question. Please consult with your vet in regards to the proper medication and dosage to use on your furry pal.
    8 months ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
    Note: Any trademarks are the property of their respective companies.
     
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