Clomipramine is used to treat separation anxiety. It is also used sometimes to treat obsessive compulsive disorders and aggression. Clomipramine requires a prescription from your veterinarian, and is sold per capsule.
For: Dogs & Cats
Benefits:
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Treats separation anxiety in pets
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Helps reduce symptoms caused by separation anxiety such as, excessive barking, inappropriate elimination, and other destructive tendencies
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Can sometimes be used to treat obsessive compulsive disorders and aggression
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It is not a tranquilizer or a sedative, and should not affect your pet's personality or memory
How it works:
Clomipramine is a tricyclic antidepressant and affects chemicals in the brain (serotonin) that may become unbalanced leading to behavioral problems in pets. Clomipramine treats separation anxiety in pets. Separation anxiety is in many cases the root cause of behaviors such as excessive barking, inappropriate elimination, and other destructive tendencies. When used in conjunction with a training program, Clomipramine may be used to help decrease or eliminate these behaviors by helping treat the root cause. In addition, it is sometimes used to treat obsessive compulsive disorders and aggression
Cautions:
Don't use Clomipramine if your pet is taking a monoamine oxidase inhibitor (MAOI) such as Anipryl, or selegiline, or has been using a Preventic Collar in the last 14 days. Clomipramine may increase the effects of other drugs and may cause drowsiness. Stop giving your pet Clomipramine and contact your vet if the pet displays any of the following reactions: difficulty breathing, hives, irregular heartbeat, difficulty urinating, seizures, fever with increased panting, muscle stiffness or weakness, or swelling of the lips, tongue, or face.
More Information:
Brand Name Anafranil (Novartis), Clomicalm (Novartis)
Generic Name Clomipramine (klo-mip’-ra-meen)
What is the most important information I should know about clomipramine: Clomipramine is a prescription medication FDA approved for veterinary use. Clomipramine is available as 20mg, 40mg and 80mg tablets. Clomipramine , FDA approved for human use, is also used in veterinary medicine and is available as 25mg, 50mg and 75mg capsules. The usual dose of clomipramine in dogs is 0.5-1.8mg per pound every 24 hours depending on the condition and the response to therapy. Clomipramine may also be useful in cats, but cats tend to be more sensitive to tricyclic antidepressant drugs. Dosing of cats may be difficult with the commercially available products. Clomipramine may not help symptoms right away. It may take a number of days before symptoms begin to lessen. Contact your veterinarian if symptoms get worse or if new symptoms develop while the pet is on this medication. Clomipramine may cause drowsiness or dizziness.
What is Clomipramine: Clomipramine is a Tricyclic antidepressant. Clomipramine affects chemicals in the brain that may become unbalanced leading to behavioral problems in pets. Clomipramine is used to treat separation anxiety. Clomipramine (Anafranil) is sometimes used to treat aggression and obsessive-compulsive disorders such as tail chasing. Clomipramine may also be used for purposes other than those listed in this guide.
What should I discuss with my veterinarian before giving clomipramine to my pet: Do not give this medication if your pet has taken or used a monoamine oxidase inhibitor (MAOI) such as selegiline, Mitaban Dip or Preventic Collar within the last 14 days. Tell your veterinarian if your pet has liver or kidney disease; asthma; thyroid disease; diabetes; stomach or intestinal problems; high blood pressure or heart disease; difficulty urinating, seizures, or glaucoma. Tell your veterinarian if the pet is pregnant or lactating.
How should this medication be given: Give this medication exactly as directed by your veterinarian. Allow pet to drink plenty of water. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store clomipramine at room temperature away from moisture and heat. Keep this medication away from children and pets.
What happens if I miss giving a dose: Give the missed dose as soon as you remember. However, if is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not give a double dose of the medication.
What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of clomipramine overdose include seizures, confusion, drowsiness, agitation, hallucinations and low blood pressure (dizziness, fatigue, fainting).
What should I avoid while giving Clomipramine to my pet: Clomipramine may cause dizziness or drowsiness. Do not stop giving clomipramine suddenly. This could cause symptoms such as nausea and malaise.
What are the possible side effects of Clomipramine: If any of the following serious side effects occur, stop giving clomipramine and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face, or hives); seizures; a fast or irregular heartbeat; high blood pressure; difficulty urinating; or fever with increased panting, muscle stiffness or muscle weakness. Other less serious side effects may occur. Continue giving clomipramine and talk to your veterinarian if your pet has drowsiness or dizziness; dry mouth and eyes; constipation; panting; mild agitation, weakness or headache; nausea or loss of weight or appetite. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.
What other drugs will affect Clomipramine: Do not give this medication if your pet has taken or used a monoamine oxidase inhibitor (MAOI) such as selegiline, Mitaban Dip or Preventic Collar within the last 14 days. Clomipramine may increase the effects of other drugs that may cause drowsiness, including other antidepressants, antihistamines, sedatives, pain relievers, anxiety medications, and muscle relaxants. Drugs other than those listed may also interact with clomipramine. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines including herbal products.
Where can I get more information: Your pharmacist has additional information about clomipramine written for health professionals that you may read.
Call your veterinarian for medical advice about any side effects to your pet. You may report side effects to the FDA at 1-800-FDA-1088.
Directions:
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Clomipramine capsules are a prescription medication used in dogs and cats to treat separation anxiety. It is also sometimes used to treat obsessive compulsive disorders and aggression.
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Clomipramine capsules are FDA approved for human use. However, it is not uncommon for veterinarians to prescribe clomipramine capsules for use in dogs and cats.
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Clomipramine capsules are classified as tricyclic antidepressants. Clomipramine capsules affect chemicals in the ;brain that may become unbalanced leading to behavioral problems in dogs and cats.
Tip: Clomicalm tablets may not help alleviate symptoms right away. It may take a number of days before symptoms begin to lessen.
Dosage:
Pet
Weight
Dosage
Dogs:
All weights
Give 0.9-1.8mg per pound of pets body weight once daily with food. Allow pet to have plenty of water to drink. Actual dosage depends on the condition being treated and the pets response to therapy
Cats:
All weights
Give 0.5mg per pound of pets body weight once daily with food. Allow pet to have plenty of water to drink. Actual dosage depends on the condition being treated and the pets response to therapy
Horses:
Storage: Store Clomipramine at room temperature away from moisture and heat.
Clomipramine has been a very helpful product that I have seen wonderful results with. I tend not to like to give medications to my pets but my dog seemed to be getting worse as the years have gone by and herbal medication for this kind of problem can have mixed results. The change in my dog is such a difference, he is relaxed, not stressed in situations that he used to be, not aggressive like he was with my younger, smaller dog like he was and is like he was when he was younger. I feel like I have my baby back.
Cllomipramine has changed my Shasta's life. She is over 13 years old now, getting blind and hard of hearing. She was getting so anxious she started running away and could not find her way home. If I locked her in the house she would climb into the claw foot bath tub and then could not get out, it was so very sad. Now we give her one pill in the morning, while I am at work she rests without looking for a place to hide and has the energy to play when I get home, Thank You
My husband passed away last year and this was his dog. I wasn't sure I would be able to keep her because she was so hyperactive. She is 12years old now. My husband claimed that her energy level would lessen as she aged - well, needless to say, it didn't. She has been taking this medication for over a year and it has helped lessen her anxiety. Except for thunderstorms and fireworks when I give her 1/2 pill of another medication (??). The addtional medication gives her some relief from shaking uncontrollably. I keep her close to me during these events and physically try to calm her but she is still nervous. With no trauma history and a very quiet environment I am sure her problem is organic.
This medicine is literally a godsend. Without it, at least one of our beagles would have been dead and I'd be a huge basketcase..
Our spayed mommy beagle has been dog aggressive with our other beagles for years. I've had some severe bites and blood would routinely flow. We couldn't tell what would set her off and I finally got fed up with her aggression when she started attacking our show puppy instead of her previous targets, our older beagles.
I'd break up the fights, I'd want to literally kill her, and I've come pretty close to snapping off one of my teeth during these events. I talked to the vet, they recommended Clomipramine, we tried it, and the aggression stopped almost immediately. I love this medicine, but like other reviewers, couldn't afford my vet's price.
So...1-800-PetMeds, you've not only saved my sanity, all of our beagles' health, and our pocket book.
Our 3.5 year old wheaten terrier has EXTREME stalking/separation anxiety. We're not sure of his previous situation, but in the two years we've had him, he's been spinning/thrashing/attacking whenever you try to go through a door, even the bathroom. My husband and I have been bitten too many times to count, but we can't give up on him. He also barks constantly in the car and if we try to leave him in the car for two seconds to drop something in a mail box, he rips apart the car. We work with a trainer, we tried an e-collar but he was conditioned to know someone was going to move when it went off, we've tried every game in the book. Even if he's dead tired, he's out to get you.
He's been attacking my husband while he's sitting on the couch or when his back is turned to him since we started this medication three months ago. We tried the name brand as well and nothing. Although, this is the medication recommended by our trainer, we're switching back to Reconcile. It made him sick at night, but it worked a little better.
the vet had given her different looking clomipramine pills than what I got here & didnt have an issue with her throwing up but now she has been & was wondering if its because of the pills.
Nausea is a common side effect with clomipramine. Vomiting associated with the nausea can result regardless of the brand of clomipramine. The first thing I would suggest is to make sure the strength you are using is the exact same strength as the previous medication. A higher dose can increase the likelihood of side effects. I would also suggest you discuss your pet's vomiting with your veterinarian.
Clomipramine is metabolized in the liver and excreted through the kidneys. Because of this, and especially in older pets, your veterinarian will most likely require periodic liver and kidney function blood tests.
My 8 lb Pomeranian only needs to take .04 ml twice a day. He was on .05 twice a day but he was losing weight. When we lowered the dosage he started eating. Since he is so small the capsules doesn't work. Please help
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.
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