What is Clomicalm?

Clomicalm (clomipramine) is used to treat separation anxiety in dogs in connection with behavior modification and training. Clomicalm requires a prescription from your veterinarian.

Due to manufacturer production issues, please see our alternatives to Clomicalm: Alternatives to Clomicalm

Benefits:
•	Treats separation anxiety in dogs
•	Helps reduce symptoms caused by separation anxiety such as, excessive barking, inappropriate elimination, and other destructive tendencies
•	It is not a tranquilizer or a sedative, and should not affect your dog's personality or memory

How it works:
Clomicalm (clomipramine) is a tricyclic antidepressant and affects chemicals in the brain (serotonin) that may become unbalanced leading to behavioral problems in dogs. Clomicalm Tablets treat separation anxiety in dogs. Separation anxiety is in many cases the root cause of behaviors such as excessive barking, inappropriate elimination, and other destructive tendencies. When used in conjunction with a training program, Clomicalm may be used to help decrease or eliminate these behaviors by helping treat the root cause.

Cautions:
Don't use Clomicalm if your pet is taking a monoamine oxidase inhibitor (MAOI) such as Anipryl, or selegiline, or has been using a Preventic Collar in the last 14 days. Clomicalm may increase the effects of other drugs and may cause drowsiness. Stop giving your pet Clomicalm and contact your vet if the pet displays any of the following reactions: difficulty breathing, hives, irregular heartbeat, difficulty urinating, seizures, fever with increased panting, muscle stiffness or weakness, or swelling of the lips, tongue, or face.

What is the most important information I should know about Clomicalm: Clomicalm is a prescription medication FDA approved for veterinary use in dogs. Clomicalm is available as 20mg, 40mg and 80mg tablets. The usual dose for dogs is 0.9-1.8mg per pound every 24 hours. Clomipramine FDA approved for human use, is also used in veterinary medicine. Clomipramine is available as 25mg, 50mg and 75mg capsules. The usual dose of Clomicalm in dogs is 0.5-1.5mg per pound every 24 hours. Clomicalm may also be useful in cats, but cats tend to be more sensitive to tricyclic antidepressant drugs. Dosing of cats may be difficult with the commercially available products. Clomicalm may not help symptoms right away. It may take a number of days before symptoms begin to lessen. Contact your veterinarian if symptoms get worse or if new symptoms develop while the pet is on this medication. Clomicalm may cause drowsiness or dizziness.

What is Clomicalm: Clomicalm (clomipramine) is a tricyclic antidepressant. Clomicalm affects chemicals in the brain that may become unbalanced leading to behavioral problems in dogs. Clomicalm is used in dogs to treat separation anxiety.

What should I discuss with my veterinarian before giving Clomicalm to my pet: Do not give this medication if your pet has taken or used a monoamine oxidase inhibitor (MAOI) such as selegiline, Mitaban Dip or Preventic Collar within the last 14 days. Tell your veterinarian if your pet has liver or kidney disease; asthma; thyroid disease; diabetes; stomach or intestinal problems; high blood pressure or heart disease; difficulty urinating, seizures, or glaucoma. Tell your veterinarian if the pet is pregnant or lactating.

How should this medication be given: Give this medication exactly as directed by your veterinarian. Allow pet to drink plenty of water. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Clomicalm at room temperature away from moisture and heat. Keep this medication away from children and pets.

What happens if I miss giving a dose: Give the missed dose as soon as you remember. However, if is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not give a double dose of the medication.

What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of Clomicalm overdose include seizures, confusion, drowsiness, agitation, hallucinations and low blood pressure (dizziness, fatigue, fainting).

What should I avoid while giving Clomicalm to my pet: Clomicalm may cause dizziness or drowsiness. Do not stop giving Clomicalm suddenly. This could cause symptoms such as nausea and malaise.

What are the possible side effects of Clomicalm: If any of the following serious side effects occur, stop giving Clomicalm and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face, or hives); seizures; a fast or irregular heartbeat; high blood pressure; difficulty urinating; or fever with increased panting, muscle stiffness or muscle weakness. Other less serious side effects may occur. Continue giving Clomicalm and talk to your veterinarian if your pet has drowsiness or dizziness; dry mouth and eyes; constipation; panting; mild agitation, weakness or headache; nausea or loss of weight or appetite. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.

What other drugs will affect Clomicalm: Do not give this medication if your pet has taken or used a monoamine oxidase inhibitor (MAOI) such as selegiline, Mitaban Dip or Preventic Collar within the last 14 days. Clomicalm may increase the effects of other drugs that may cause drowsiness, including other antidepressants, antihistamines, sedatives, pain relievers, anxiety medications, and muscle relaxants. Drugs other than those listed may also interact with Clomicalm. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines including herbal products.

Where can I get more information: Your pharmacist has additional information about Clomicalm written for health professionals that you may read.

Directions:

•	Clomicalm tablets are a prescription medication used in dogs to treat separation anxiety.
•	Clomicalm tablets are not for cats.
•	Clomicalm tablets are classified as a tricyclic antidepressant. Clomicalm tablets affect chemicals in the brain that may become unbalanced leading to behavioral problems in dogs.
•	Clomicalm tablets can be administered as a single daily dose or twice daily based on pets response. To minimize side effects, you may want to initiate treatment in divided doses.