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Product Info
How to Use
Customer Reviews
Product Info
What is Amlodipine?

Amlodipine besylate is used in cats for the treatment of systemic hypertension (high blood pressure). Although Amlodipine besylate is not FDA-approved for use in veterinary medicine, it is a commonly accepted practice for veterinarians to prescribe this medication for cats. Amlodipine requires a prescription from your veterinarian, and is sold per tablet.



  • Treats high blood pressure in cats
  • Relaxes the arterial muscles to help decrease blood pressure
How it Works:

Amlodipine is known as a calcium-channel blocker. It works by blocking the calcium needed for muscle contraction. Amlodipine works primarily on the arterial muscles to relax them so they can dilate and the blood pressure decreases.


Notify your doctor if your cat has liver problems before administering this medication. Amlodipine should not be used in pregnant or lactating animals. In rare instances, Amlodipine is used in dogs. If used in a dog, this medication may also cause the blood to take longer to clot.

Brand Name:


Generic Name:

amlodipine besylate

What is the most important information I should know about amlodipine besylate:

Amlodipine besylate is a prescription medication not FDA approved for veterinary use; however, it is a commonly accepted practice for veterinarians to use this medication in cats. Amlodipine besylate is available as 2.5mg tablets. The usual dose to treat systemic hypertension is 0.625mg (1/4 of a 2.5mg tablet) by mouth once a day.

What is Amlodipine besylate:

Amlodipine besylate is a calcium channel blocker. Calcium channel blockers affect the heart and blood vessels. Amlodipine besylate is used to treat certain high blood pressure especially in cats with kidney disease. Amlodipine besylate may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving amlodipine besylate to my pet:

Tell your veterinarian if your pet has heart disease, or liver disease. Tell your veterinarian if your pet is pregnant or nursing.

How should this medication be given:

Give this medication exactly as directed by your veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Amlodipine besylate can be given with food. Do not stop giving amlodipine besylate. A missed dose can result in a sudden rise in blood pressure which can lead to blindness, kidney damage, seizures, or collapse. Store amlodipine besylate at room temperature away from moisture and heat. Keep this medication away from children and pets.

What happens if I miss giving a dose:

Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose the pet:

Seek emergency veterinary medical treatment. Symptoms of amlodipine besylate overdose include staggering due to dizziness, collapse, or slow heart rate.

What should I avoid while giving Amlodipine besylate to my pet:

Amlodipine besylate should not be used in animals allergic to it. Use amlodipine besylate with caution in animals with heart failure or liver disease. Do not use in breeding, pregnant, or nursing females. Do not use in breeding males.

What are the possible side effects of Amlodipine besylate:

For dogs and cats, if any of the following serious side effects occur, stop giving amlodipine besylate and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips; tongue or face; hives). In cats side effects are rare but may include drowsiness, loss of appetite, weight loss, swelling of the gums, or rapid heart rate. In dogs, may also cause the blood to take longer to clot. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.

What other drugs will affect Amlodipine besylate:

Tell your veterinarian if your pet is being given aspirin, warfarin (Coumadin), diuretics (furosemide, Salix), beta blockers (atenolol), and other blood pressure medications. Drugs other than those listed may also interact with amlodipine besylate. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines including vitamins, and supplements.

Where can I get more information:

Your pharmacist has additional information about Amlodipine besylate written for health professionals that you may read. Call your veterinarian for medical advice about any side effects to your pet. You may report side effects to the FDA at 1-800-FDA-1088.

How to Use
  • Give Amlodipine to your cat exactly as your veterinarian prescribes.
  • If you miss giving your cat a dose of Amlodipine, give the next dose as soon as you remember or, if it is close to the next scheduled dose, return to the regular schedule. Do not double the dose to catch up.

The medication can be given with food.

All weights
0.625mg (1/4 of a 2.5 mg tablet) once a day.
Do not use!
Do not use!

Store this product at room temperature.

Active Ingredients
Amlodipine besylate
2.5 mg
Customer Reviews
Amlodipine is rated 4.2 out of 5 by 5.
Rated 4 out of 5 by from Reduced calico cat's blood pressure My cat, Lexi, has hyperthyroidism for a few years. The meds manage her thyroid and keeps her weight up, but was not controlling her blood pressure. We have her checked every 6 months or so. One morning she had a bloody nose. We were distressed of course and took her to the vet. Her blood pressure was high. She was prescribed Amlodipine 2.5mg which I was getting from the local pharmacy. I was giving her 1/4 pill/day so the 7 pills I was getting each month was for approx. a month, 28 days. But, the price was $10.00 each time I filled the prescription. Was happy to be able to get Amlodipine here because the cost is so much better for a drug that is prolonging my 14 year old cat's life.
Date published: 2014-08-04
Rated 5 out of 5 by from Works for us! My 16 year old cat suddenly went blind, so I rushed her to the animal hospital. The vet said that her blood pressure was through the roof (220-250). We started with 1/4 tablet, but that wasn't doing the trick. So we upped it to 1 tablet. She was doing better, but not great, so we upped it to 2 tablets. She can now see, and has gained a bit of weight back since she is less timid and scared. Her blood pressure is about 180, which is still high. We are now up to 2 and a 1/4 tablets, so I'm hoping it's helping her even more. The pills are small and she tolerates my throwing them down her throat on a daily basis...
Date published: 2014-02-16
Rated 2 out of 5 by from My 20 year old cat has been on a low dose (6.25) of amlodipine for about 10days ...and she now hisses whenever I pick her up, put her down, pet her, etc. Is it possible this is a reaction to the drug?
Date published: 2013-11-04
Rated 5 out of 5 by from Reversed Blindness!! My 16 year old cat went blind. The vet said there was nothing that could be done. She said that the blindness was probably caused by a brain thing. My husband looked up on internet,"Sudden Blindness in Cats". An article said that blindness could be brought on by high blood pressure (causing detached retinas). My vet hadn't even checked my cat's blood pressure. We brought our cat back to the vet. My cat's blood pressure was borderline high. The vet prescribed amlodipine (1/4 pill, 2.5 mg) along with enalapril (2.5 mg). Both pills once a day. After two days, my cat can see!! It is like a miracle!!
Date published: 2012-10-15
Rated 5 out of 5 by from Helped my kitty so much!! In three short weeks, 1/2 a pill per day brought my cat's blood pressure down from over 200 to below 150. My cat seems very happy, and so am I. Putting it in a treat seems to work best for us, much better than the pill popper thing. I am glad her vet recommended this medicine for her. :)
Date published: 2011-01-30
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Any hints about how to split the 2.5 mg amlodipine tablets into 4 parts without shattering the tablet?

Asked by: flash
Tanya's CRF board suggests that you snap it in half with your fingers first and then - using tweezers to hold one half at exactly ITS half point - use your fingers to snap the fourth off.
Answered by: Melissa
Date published: 2015-08-06

is amlodipine a directic

Asked by: moosie
No, amlodipine is not a water pill or duiretic like for example furosemide (salix) is. Amlodipine controls blood pressure through a different mechanism. It is a calcium channel blocker. It relaxes arterial muscles to help decrease blood pressure.
Answered by: Linda M 1800petmeds pharmacist
Date published: 2015-06-30


can this pill upset my cats stomach
Asked by: doppy
It is possible this medication may cause loss of appetite in cats. Please be sure to contact your veterinarian if your pet is experiencing any side effects.
Answered by: Stephanie Duesler, Pharm. D, MBA
Date published: 2015-05-14

Can i buy this with a prescription from vet in UK

I am unable to buy this drug on prescription in the UK even though my Vet will write a script for it, is it possible to buy it from you and have it shipped to me?
Asked by: BSPM
We do accept international prescriptions from licensed veterinarians.
Answered by: Stephanie Duesler, Pharm. D, MBA
Date published: 2015-03-26

Is this medicine available in a smaller dose?

Smaller dose I mean 0.625mg(tiny tabs), This is the size my cat is taking.
Asked by: Cyndi
The smallest size tablets available for amlodipine is 2.5mg, otherwise you may have to see if you can get it compounded into the appropriate dose for your cat.
Answered by: Pharmacist
Date published: 2014-06-03

How hard is the pill

I have had trouble cutting these pills in quarters. If this is made by a different supplier perhaps it will be easier to cut in fourths.
Asked by: Ted
Pill cutter shattered THIS PILL. Even bits would not dissolve in water or oil. Pharmacy "compounded" it for me in liquid; will try now. It has sugar so if pet is diabetic, can't use this. Thyroid med for cat divided and dissolved well in water...???
Answered by: purplecat
Date published: 2013-08-14

Can this medicine be safely given to humans

Asked by: Tiny
Amlodipine is a medication with FDA approval for use in humans under the direct supervision of a licensed medical physician.
Answered by: Lilli Pharmacist
Date published: 2013-06-24


Amlodipine besylate is used in cats for the treatment of systemic hypertension (high blood pressure). i ask before about the size of this pill, if it is used a lot for treating cats and dogs , what about making the pill a small dose, or making the pill larger so we can cut it, like flatting it so it can be cut in size we need it.
Asked by: arbuck1
We do not manufacture the tablet; therefore, the size cannot be changed. We do not compound Amlodipine; however, your local compounding pharmacy may. Check with them to see if it can be compounded in the dose you need.
Answered by: Lisa M
Date published: 2013-02-19
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