Especially good for breeds prone to blood flow abnormalities
How it works: Allopurinol belongs to a class of drugs called xanthine oxidase inhibitors which prevent the accumulation of uric acid. If uric acid accumulates in the body, crystals form in the urine which may congregate to produce kidney or bladder stones.
Cautions: Allopurinol should be given with meals. It should not be given to pregnant or nursing animals and should not be used in puppies.
More Information:
Brand Name Zyloprim (GlaxoSmithKline)
Generic Name Allopurinol
What is the most important information I should know about allopurinol: Allopurinol is a prescription medication not FDA approved for veterinary use; however, it is a commonly accepted practice for veterinarians to use this medication in dogs. Allopurinol is available as 100mg and 300mg scored tablets. The usual initial dose for dogs is 5mg/pound given with food once a day. Water should be kept available for the pet to drink. Allopurinol may cause drowsiness
What is Allopurinol:
Allopurinol reduces the production of uric acid in the body. Allopurinol helps prevent the formation of bladder stones in dogs that are caused by high levels of uric acid. Allopurinol may also be used for purposes other than those listed in this guide.
What should I discuss with my veterinarian before giving allopurinol to my pet:
Tell your veterinarian if your pet has liver or kidney disease or if the pet is pregnant or lactating. Inform your veterinarian of any other medications, including vitamins and supplements your pet may be taking while receiving Allopurinol.
How should this medication be given:
Give this medication exactly as directed by your veterinarian. Allopurinol should be given with food to lessen stomach upset. Allopurinol should be given with lots of water. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store allopurinol at room temperature away from moisture and heat. Keep this medication away from children and pets.
What happens if I miss giving a dose:
Give the missed dose as soon as you remember during the same day. However, if you don¿t remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.
What happens if I overdose the pet:
Seek emergency veterinary medical treatment. Symptoms of allopurinol overdose are not known.
What should I avoid while giving Allopurinol to my pet:
Allopurinol may cause drowsiness.
What are the possible side effects of Allopurinol:
If any of the following serious side effects occur, stop giving allopurinol and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips; tongue or face; hives), blood in the urine or pain when urinating, a rash, eye irritation, fever, chills or joint aches or severe nausea or vomiting. Other less serious side effects may occur. Continue giving allopurinol and talk to your veterinarian if your pet experiences upset stomach or diarrhea, dizziness or drowsiness or an acute attack of arthritis. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.
What other drugs will affect Allopurinol:
Ampicillin or amoxicillin may increase the risk that a rash may develop. Tell your veterinarian if your pet is being given a thiazide diuretic, azathioprine, drugs used to treat cancer, cyclosporine, warfarin or theophylline. Drugs other than those listed may also interact with allopurinol. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines.
Where can I get more information:
Your pharmacist has additional information about Allopurinol written for health professionals that you may read.
Call your veterinarian for medical advice about any side effects to your pet. You may report side effects to the FDA at 1-800-FDA-1088.
Directions:
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Allopurinol is a prescription medication used in dogs for the prevention of urate bladder stones.
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Allopurinol is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to prescribe this medication for dogs.
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Allopurinol should be used in adult dogs only. Do not use in puppies, kittens, or cats.
Tip: The medication should be given with meals. Water should be kept available for the pet. Allopurinol may cause drowsiness.
Dosage:
Pet
Weight
Dosage
Dogs:
All weights
Give 5mg per pound of pet’s body weight once a day with food
Cats/Kittens:
Horses:
Storage: Should be stored at room temperature, away from moisture and heat.
my app. 11 yr old heinz 57 dog that I have no history on has been vomiting yellow bile looking fluid last two-three days but is eating,urinating,bowels o.k. and every other aspect o.k. Any suggestions or just see our vet ?
My 5 lb. 11 year yorkie has suffered from stones all her life. Ultasounds showed that her kidneys contain many stones. The last stone she passed was a urate stone. However, I believe she may have had struvite stones in the past, but not sure.
Allopurinol is used in the treatment of urate stones. Struvite stones are dissolved by making the urine acidic. Methio-Form is a urinary acidifier available by prescription. There are diets available to treat struvite stones as well.
Calcium oxalate stones are usually removed surgically. However, with proper diet and drinking plenty of fluids the chance of formation is reduced. Calcium citrate (Urocit-K) is a prescription medication used to reduce formation of calcium oxalate stones.
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.