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Advantage II

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Advantage II?

Advantage II is a monthly flea preventative for dogs and cats that offers comprehensive flea protection by killing adult fleas, larvae, and eggs. Plus, it kills fleas through contact, which means fleas don't have to bite your pet to die. Advantage II also treats, prevents, and controls lice on dogs. Advantage II does not kill ticks, so we recommend using the Preventic Tick Collar along with Advantage II (dogs only). Advantage II for small cats 5-9 lbs can also be used for ferrets weighing 1 lb or over and 10 weeks of age or older.

For:

Dogs (3 lbs or over and 7 weeks of age or older), Cats (2 lbs or over and 8 weeks of age or older), Ferrets (1 lb or over and 10 weeks of age or older)

Benefits:
  • Convenient, once-a-month application
  • Kills through contact - fleas don't have to bite to die
  • Kills fleas within 12 hours of application on cats and dogs
  • Kills fleas within 24 hours of application on ferrets
  • Kills all flea life stages including flea eggs and larvae to prevent infestation
  • Treats, prevents, and controls lice infestations (dogs only)
  • Safe and easy to apply
  • Waterproof - remains effective even if pet gets wet (use of a soap-free shampoo is recommended)
How it Works:

The first active ingredient is imidacloprid, which acts on the nervous system of the flea to cause paralysis and subsequent death. Within 12 hours of application on cats and dogs, 98-100 percent of fleas are dead. Advantage II Small Cat kills the existing fleas on ferrets within 24 hours. The second active ingredient, pyriproxyfen, is an insect growth regulator. Once a female flea lays her eggs, pyriproxyfen works to prevent the eggs from hatching, ending the flea life cycle. Also, the active ingredient in Advantage II kills through contact, which means that fleas don't have to bite your pet to die. Reinfesting fleas are killed with protection against further flea infestation lasting for up to 4 weeks. Pre-existing pupae in the environment may continue to emerge for 6 weeks or longer depending upon the climactic conditions.

Cautions:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become severe, consult a veterinarian immediately. Do not get this product in your pet's eyes or mouth.

Brand Name:

Advantage II (Bayer)

Active Ingredient(s):

Imidacloprid (9.1%), Pyriproxyfen (0.46%) Other ingredients (90.44%)

What is this product used for:

Advantage II Kitten, Advantage II Small Cat and Advantage II Large Cat are once a month topical flea prevention and treatment for cats and kittens over 8 weeks or older. Advantage II Small Cat may also be used for ferrets weighing 1 lb or over and 10 weeks of age or older. Advantage II Small Dog, Advantage II Medium Dog, Advantage II Large Dog, and Advantage II Extra Large Dog are once a month topical flea prevention and treatment for dogs and puppies 4 lbs or more and 7 weeks or older. Advantage II kills all flea life stages. Advantage II kills fleas within 12 hours of application. Advantage II for Dogs also treats, prevents, and controls lice infestations. Advantage II is waterproof and fragrance free.

Availability:

Advantage II for cats or ferrets and Advantage II for dogs are non-prescription (OTC) products.

How this product should be used:

Advantage II Kitten is available in 0.23 ml applicators for kittens 2-5 lbs (turquoise). Advantage II Small Cat is available in 0.4 ml applicators for cats 5-9 lbs or ferrets weighing 1 lb or over and 10 weeks of age or older (orange). Advantage II Large Cat is available in 0.8 ml applicators for cats 9 lbs & up (purple). Advantage II Small Dog is available in 0.4 ml applicators for dogs 3-10 lbs (green). Advantage II Medium Dog is available in 1.0 ml applicators for dogs 11-20 lbs (teal). Advantage II Large Dog is available in 2.5 ml applicators for dogs 21-55 lbs (red). Advantage II Extra Large Dog is available in 4.0 ml applicators for dogs over 55 lbs (blue). To apply, place the applicator tip through your pet's hair to the skin level. On cats and ferrets, apply to skin on neck at the base of the skull. For dogs up to 20 lbs, apply to skin on back between the shoulder blades. For dogs 21 lbs or over apply the contents of one tube to 3 or 4 spots along the skin on back from the shoulder to the tail. Do not get this product in the pet's eyes or mouth.

What are the side effects:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become more severe, consult a veterinarian immediately.

What special precautions are there:

Advantage II is for external use on dogs and puppies 3 lbs or more and 7 weeks or older, cats and kittens 2 lbs or more and 8 weeks or older, or ferrets weighing 1 lb or over and 10 weeks of age or older. Consult a veterinarian before using on medicated pets, if the pet is being given this product along with other pesticides, and debilitated, aged, pregnant or nursing pets. This product causes eye irritation in humans and is harmful if swallowed. Avoid contact with skin. Call poison control center if swallowed. If on skin, wash with plenty of soap and water. If in eyes, flush with plenty of water.

In the event of overdose:

Contact your veterinarian or veterinary emergency room.

How should I store this product:

Store this product in a cool dry place. Do not store in the refrigerator. Do not reuse empty container. Do not contaminate water, food or feed by storage or disposal. To dispose of empty container place in trash or offer for recycling if available. If container is partly filled call local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain. Keep out of reach of children and pets.

How to Use
Directions:
  • Only use Advantage II on dogs/puppies over 3 lbs and over 7 weeks of age, cats/kittens over 2 lbs and over 8 weeks of age, and ferrets 1 lb or over and 10 weeks of age or older.
  • Apply Advantage II once a month every month.
  • For dogs up to 20 lbs, part the pet's hair between the shoulder blades until you can see the skin. Place the tip of the applicator on the skin and release all of the tube's contents on a single spot directly on the skin.
  • For dogs 21 lbs and over, apply entire contents of the tube evenly in 3 or 4 spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the applicator on the skin and release a portion of the Advantage II solution directly on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog.
  • For kittens, cats and ferrets, place the applicator tip through the cat's hair to the skin on the neck at the base of the skull and release all of the tube's contents on a single spot directly on the skin.
  • Use only one applicator per treatment.
Tip:

Under normal conditions Advantage II is effective for a month. However, in case of severe flea infestation, retreatment may be necessary earlier than four weeks. Do not re-treat cats or dogs more often than once every 7 days. For ferrets, do not retreat more often than every 14 days. After flea control is obtained, return to a monthly treatment.

Dosage:
Dogs/Puppies: (7 weeks of age or older)
Weight
Dosage
3-10 lbs
Apply contents of 1 applicator once a month (Green Box)
11-20 lbs
Apply contents of 1 applicator once a month (Teal Box)
21-55 lbs
Apply contents of 1 applicator once a month (Red Box)
Over 55 lbs
Apply contents of 1 applicator once a month (Blue Box)
Kittens: (8 weeks of age or older)
Weight
Dosage
2-5 lbs
Apply contents of 1 applicator once a month (Turquoise Box)
Cats: (8 weeks of age or older)
Ferrets: (1 lb or over and 10 weeks of age or older)
Weight
Dosage
Ferrets 1+ lbs
Apply contents of 1 applicator once a month (Orange Box)
5-9 lbs
Apply contents of 1 applicator once a month (Orange Box)
9 lbs & up
Apply contents of 1 applicator once a month (Purple Box)
Horses:
Do not use!
Storage:

Should be stored in a cool dry place. Do not refrigerate.

Ingredients
Advantage II for Kittens 2-5 lbs (Kitten - Turquoise Box) (0.23 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Cats 5- 9 lbs or Ferrets 1 lb or over and 10 weeks of age or older (Small Cat - Orange Box) (0.4 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Cats Over 9 lbs (Large Cat - Purple Box) (0.8 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 3 to 10 lbs (Small Dog - Green Box) (0.4 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 11 to 20 lbs (Medium Dog - Teal Box) (1.0 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 21 to 55 lbs (Large Dog - Red Box) (2.5 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 55 lbs and Over (Extra Large Dog - Blue Box) (4.0 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Customer Reviews
Advantage II is rated 4.239812477461233 out of 5 by 2,773.
Rated 5 out of 5 by from Let me telk you! This stuff works!! I put it on my three cats and after the first 3 hours there were fleas on the beds they laid on!! I recommend for good successful treatment to sweep everything and I mean EVERYTHING! not just rugs, couches, and hardwood I also mean stairs and legs of chairs!! Also wash all human bedding and pet bedding immediately after application. Those little boogers are sneaky. But this medicine helped so much and with daily sweeps I see nothing!
Date published: 2016-08-17
Rated 5 out of 5 by from love this product advantage ll i started using this product at the beginning of spring.. and this year i have been totally flea free,, what a blessing in the past nothing else has worked... this year no one is itching me or the cats.... try this product it is a sure relief for all....
Date published: 2016-08-17
Rated 5 out of 5 by from Great stuff... I use Advantage 11 on my 4 cats and it works wonderfully. I would and have recommended it to other people. Can't get it at the Vet anymore so I was so glad to find this Website. The prices are great and the flea drops work wonders...
Date published: 2016-08-13
Rated 5 out of 5 by from Worked like a charm Exceeded my expectations....my indoor cats already had fleas before I noticed the problem. We medicated them all with Advantage 2 and it worked quickly and thoroughly with no adverse side effects at all. I am finding dead fleas on their pet beds... I highly recommend this for your cats. Very pleased.
Date published: 2016-08-10
Rated 5 out of 5 by from Overwhelmingly good This Advantage II works when Nothing else did .
Date published: 2016-08-07
Rated 5 out of 5 by from I sugest you should read costumer reviews I strongly suggest a person should read "costumer reviews" before buying any pet care product. I have 7 cats & kittens & they have had no adverse reactions using Advantage 2. Be sure to buy the correct Advantage 2 product for the weight of your cat & carefully follow all directions.
Date published: 2016-07-23
Rated 5 out of 5 by from Execellent Flea Medicine Easy to apply and I think it works great on my cats and will get again if I need to
Date published: 2016-07-23
Rated 4 out of 5 by from SWITCH BACK I've used this for several years and then decided to go with a cheaper spot on. Well, as you can see I went back to old faithful. It'll probably take a couple a months for it to start controlling fleas like it used to.
Date published: 2016-07-18
  • 2016-08-23T06:02CST
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Q&A

My 4 month old, 4 lb kitten was treated last night at 10 pm but I'm still seeing live fleas. What do you recommend?

Asked by: Msnard
It will take about 12 hours for Advantage II to take full effect. If you are still seeing fleas after a day, contact your vet for a possible alternative.
Answered by: paulpharmacistintern
Date published: 2016-08-17

Due to a death in my cat family, I have 3 vials of small cat advantage and one 14# cat.  Is there a way I can use these meds

Asked by: Judy
Although there may be a way you could use those, it'd be better to get a new prescription for your 14 pound cat. Check with your veterinarian about the possibility, and to get a future script.
Answered by: paulpharmacistintern
Date published: 2016-08-10

Gave advantage to my cat flees are coming off him but he is itching badly

Asked by: kimb
Your cat may be scratching as the fleas die. If the scratching persists or live fleas are still present, call your veterinarian.
Answered by: paulpharmacistintern
Date published: 2016-08-10

Do you accept the animal care credit as payment

Asked by: lesa
I'm so sorry, we do not accept care credit for payment. However, we do accept credit cards, debit cards, check by phone, money orders and checks by mail.
Answered by: Cherley Petmeds Pro
Date published: 2016-08-06

I have indoor cat: treated house,  gave cat Capstan &  bathed him with Dawn. How soon can I treat him with Advantage II? Also, found out cat is allergic to fleas andand lost some hair, will it grow back? 

Asked by: Flyer
I do not know about the hairloss, but you can start Advantage II the same day, after your cat is fairly dry.
Answered by: paulpharmacistintern
Date published: 2016-08-03

My cat weights 8.5 lbs. I am thinking of purchasing advantage for large cats. is that dose ok?

Asked by: Mitzi
That is a judgment call with you and your veterinarian. If your cat is normally under 9 pounds it might be better to get the orange box.
Answered by: paulpharmacistintern
Date published: 2016-08-03

I need cat not dog advantage 

Asked by: Jill
We do have Advantage II available for cats and dogs. Once you click on the Advantage II box, it should allow you to select it for either a dog or cat and the weight range before adding it to your cart.
Answered by: Cherley Petmeds Pro
Date published: 2016-08-03

I have a English Mastiff who weighs 227 pounds. Generally large dog flea medication goes to around 140 pounds. So he gets a dose of large dog and a dose of medium dog to cover his weight. It doesn't seem right that I would put 4 applications on at once?

Asked by: alyssa
The Advantage II for extra large dogs 55 lbs and over is safe for dogs up to 200 lbs. One dose of 21-55 lbs and one dose for dogs 55 lbs and over should be enough coverage for your furry baby.
Answered by: Cherley Petmeds Pro
Date published: 2016-08-03
  • 2016-08-23T06:15CST
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