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Advantage II

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Advantage II?

Advantage II is a monthly flea preventative for dogs and cats that offers comprehensive flea protection by killing adult fleas, larvae, and eggs. Plus, it kills fleas through contact, which means fleas don't have to bite your pet to die. Advantage II also treats, prevents, and controls lice on dogs. Advantage II does not kill ticks, so we recommend using the Preventic Tick Collar along with Advantage II (dogs only). Advantage II for small cats 5-9 lbs can also be used for ferrets weighing 1 lb or over and 10 weeks of age or older.

For:

Dogs (3 lbs or over and 7 weeks of age or older), Cats (2 lbs or over and 8 weeks of age or older), Ferrets (1 lb or over and 10 weeks of age or older)

Benefits:
  • Convenient, once-a-month application
  • Kills through contact - fleas don't have to bite to die
  • Kills fleas within 12 hours of application on cats and dogs
  • Kills fleas within 24 hours of application on ferrets
  • Kills all flea life stages including flea eggs and larvae to prevent infestation
  • Treats, prevents, and controls lice infestations (dogs only)
  • Safe and easy to apply
  • Waterproof - remains effective even if pet gets wet (use of a soap-free shampoo is recommended)
How it Works:

The first active ingredient is imidacloprid, which acts on the nervous system of the flea to cause paralysis and subsequent death. Within 12 hours of application on cats and dogs, 98-100 percent of fleas are dead. Advantage II Small Cat kills the existing fleas on ferrets within 24 hours. The second active ingredient, pyriproxyfen, is an insect growth regulator. Once a female flea lays her eggs, pyriproxyfen works to prevent the eggs from hatching, ending the flea life cycle. Also, the active ingredient in Advantage II kills through contact, which means that fleas don't have to bite your pet to die. Reinfesting fleas are killed with protection against further flea infestation lasting for up to 4 weeks. Pre-existing pupae in the environment may continue to emerge for 6 weeks or longer depending upon the climactic conditions.

Cautions:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become severe, consult a veterinarian immediately. Do not get this product in your pet's eyes or mouth.

Brand Name:

Advantage II (Bayer)

Active Ingredient(s):

Imidacloprid (9.1%), Pyriproxyfen (0.46%) Other ingredients (90.44%)

What is this product used for:

Advantage II Kitten, Advantage II Small Cat and Advantage II Large Cat are once a month topical flea prevention and treatment for cats and kittens over 8 weeks or older. Advantage II Small Cat may also be used for ferrets weighing 1 lb or over and 10 weeks of age or older. Advantage II Small Dog, Advantage II Medium Dog, Advantage II Large Dog, and Advantage II Extra Large Dog are once a month topical flea prevention and treatment for dogs and puppies 4 lbs or more and 7 weeks or older. Advantage II kills all flea life stages. Advantage II kills fleas within 12 hours of application. Advantage II for Dogs also treats, prevents, and controls lice infestations. Advantage II is waterproof and fragrance free.

Availability:

Advantage II for cats or ferrets and Advantage II for dogs are non-prescription (OTC) products.

How this product should be used:

Advantage II Kitten is available in 0.23 ml applicators for kittens 2-5 lbs (turquoise). Advantage II Small Cat is available in 0.4 ml applicators for cats 5-9 lbs or ferrets weighing 1 lb or over and 10 weeks of age or older (orange). Advantage II Large Cat is available in 0.8 ml applicators for cats 9 lbs & up (purple). Advantage II Small Dog is available in 0.4 ml applicators for dogs 3-10 lbs (green). Advantage II Medium Dog is available in 1.0 ml applicators for dogs 11-20 lbs (teal). Advantage II Large Dog is available in 2.5 ml applicators for dogs 21-55 lbs (red). Advantage II Extra Large Dog is available in 4.0 ml applicators for dogs over 55 lbs (blue). To apply, place the applicator tip through your pet's hair to the skin level. On cats and ferrets, apply to skin on neck at the base of the skull. For dogs up to 20 lbs, apply to skin on back between the shoulder blades. For dogs 21 lbs or over apply the contents of one tube to 3 or 4 spots along the skin on back from the shoulder to the tail. Do not get this product in the pet's eyes or mouth.

What are the side effects:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become more severe, consult a veterinarian immediately.

What special precautions are there:

Advantage II is for external use on dogs and puppies 3 lbs or more and 7 weeks or older, cats and kittens 2 lbs or more and 8 weeks or older, or ferrets weighing 1 lb or over and 10 weeks of age or older. Consult a veterinarian before using on medicated pets, if the pet is being given this product along with other pesticides, and debilitated, aged, pregnant or nursing pets. This product causes eye irritation in humans and is harmful if swallowed. Avoid contact with skin. Call poison control center if swallowed. If on skin, wash with plenty of soap and water. If in eyes, flush with plenty of water.

In the event of overdose:

Contact your veterinarian or veterinary emergency room.

How should I store this product:

Store this product in a cool dry place. Do not store in the refrigerator. Do not reuse empty container. Do not contaminate water, food or feed by storage or disposal. To dispose of empty container place in trash or offer for recycling if available. If container is partly filled call local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain. Keep out of reach of children and pets.

How to Use
Directions:
  • Only use Advantage II on dogs/puppies over 3 lbs and over 7 weeks of age, cats/kittens over 2 lbs and over 8 weeks of age, and ferrets 1 lb or over and 10 weeks of age or older.
  • Apply Advantage II once a month every month.
  • For dogs up to 20 lbs, part the pet's hair between the shoulder blades until you can see the skin. Place the tip of the applicator on the skin and release all of the tube's contents on a single spot directly on the skin.
  • For dogs 21 lbs and over, apply entire contents of the tube evenly in 3 or 4 spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the applicator on the skin and release a portion of the Advantage II solution directly on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog.
  • For kittens, cats and ferrets, place the applicator tip through the cat's hair to the skin on the neck at the base of the skull and release all of the tube's contents on a single spot directly on the skin.
  • Use only one applicator per treatment.
Tip:

Under normal conditions Advantage II is effective for a month. However, in case of severe flea infestation, retreatment may be necessary earlier than four weeks. Do not re-treat cats or dogs more often than once every 7 days. For ferrets, do not retreat more often than every 14 days. After flea control is obtained, return to a monthly treatment.

Dosage:
Dogs/Puppies: (7 weeks of age or older)
Weight
Dosage
3-10 lbs
Apply contents of 1 applicator once a month (Green Box)
11-20 lbs
Apply contents of 1 applicator once a month (Teal Box)
21-55 lbs
Apply contents of 1 applicator once a month (Red Box)
Over 55 lbs
Apply contents of 1 applicator once a month (Blue Box)
Kittens: (8 weeks of age or older)
Weight
Dosage
2-5 lbs
Apply contents of 1 applicator once a month (Turquoise Box)
Cats: (8 weeks of age or older)
Ferrets: (1 lb or over and 10 weeks of age or older)
Weight
Dosage
Ferrets 1+ lbs
Apply contents of 1 applicator once a month (Orange Box)
5-9 lbs
Apply contents of 1 applicator once a month (Orange Box)
9 lbs & up
Apply contents of 1 applicator once a month (Purple Box)
Horses:
Do not use!
Storage:

Should be stored in a cool dry place. Do not refrigerate.

Ingredients
Advantage II for Kittens 2-5 lbs (Kitten - Turquoise Box) (0.23 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Cats 5- 9 lbs or Ferrets 1 lb or over and 10 weeks of age or older (Small Cat - Orange Box) (0.4 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Cats Over 9 lbs (Large Cat - Purple Box) (0.8 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 3 to 10 lbs (Small Dog - Green Box) (0.4 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 11 to 20 lbs (Medium Dog - Teal Box) (1.0 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 21 to 55 lbs (Large Dog - Red Box) (2.5 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 55 lbs and Over (Extra Large Dog - Blue Box) (4.0 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Customer Reviews
Advantage II is rated 4.242109038737446 out of 5 by 2,788.
Rated 4 out of 5 by from Same as from the vet This is the same product as the vet has only cheaper price. We have 3 cats & it works well.
Date published: 2016-09-19
Rated 5 out of 5 by from Gets rid of the fleas! I'm really happy with this particular brand. I did some research on flea treatments, and this had the best reviews. My cats seem happier, too, and I will continue to use Advantage II.
Date published: 2016-09-19
Rated 5 out of 5 by from Quick and easy Never seen a product work so fast and efficiently. In less than 15 hrs. the cat was just about flea free. Tried others and Advantage is by far tops in my book.
Date published: 2016-09-14
Rated 5 out of 5 by from Fleas gone! After having my dogs and cat on a generic Frontline Plus all summer, the fleas moved in. I was refunded for all the unopened Fleas5x Plus I had ordered (thanks PetMeds!). Advantage II knocked them right out. I could not be happier with PetMeds' service or Advantage II.
Date published: 2016-09-09
Rated 3 out of 5 by from not the best but not horrible My cats still get bit by fleas and one of them even ended up with worms after eating a flea, so it's not like it repels fleas, but it does greatly reduce infestations. It's not the best flea medicine in the world but it doesn't make them sick and it's affordable and allows for the infestations to be minimized and manageable.
Date published: 2016-09-04
Rated 5 out of 5 by from Peace at Last!! My cats and I had been miserable since April with the flea prevention med they were on...constant scratching, licking and chewing, the both had a horrible skin irritation and LOTS of hairballs, not to mention a couple of pretty mangy-looking cats! 2 weeks ago I put them on Advantage II at my neighbor's suggestion, and I can't believe it, in 2 weeks' time their skin irritation is gone, no hairballs in 1.5 weeks, and all the licking, scratching and chewing has stopped. Lucky and Yankee are very happy and grateful!
Date published: 2016-09-03
Rated 5 out of 5 by from This product works! After terrible flea problems this summer and wasted time and money on other products that didn't work ...Finally flea free on my small rat terrier! Within 12 hours of applying I'm not seeing one single live flea on my girl. A pile of dead fleas was on her bedding the next morning. The only noticeable side effect she had was mild lethargy the day after applying. Wish I would've tried Advantage to begin with. And petmeds.com was great!
Date published: 2016-09-03
Rated 5 out of 5 by from Best product for best price. I have a 5 month old chiweenie. He didn't really have fleas, but wanted to get him some of this just incase. I've looked at Walmart, Petsmart, Target and other local pet stores and pet meds has the best deal. No complaints at all. (Other than he didn't understand why I wouldn't pet him for an hour or two lol) Thanks for the milk bone you guys sent with it!
Date published: 2016-09-03
  • 2016-09-27T06:02CST
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Q&A

Can I use it on my 10lb lop eared bunny? She is almost 2 years old

Asked by: Kelpie
This product is formulated for Dogs (3 lbs or over and 7 weeks of age or older), Cats (2 lbs or over and 8 weeks of age or older), Ferrets (1 lb or over and 10 weeks of age or older). Please consult with your vet to make sure it is safe to use on your furry baby.
Answered by: Cherley Petmeds Pro
Date published: 2016-09-26

Will you ship to canada

Asked by: Barbidrap
Yes, we do ship to Canada. Please note, there is a $14.99 shipping fee on orders shipped to Canada.
Answered by: Cherley Petmeds Pro
Date published: 2016-09-13

Does Advantage II for cats protect against ticks also?

Asked by: Julie
No, Advantage II is not effective against ticks. This product kills fleas within 12 hours of application on cats and dogs. Kills fleas within 24 hours of application on ferrets Kills all flea life stages including flea eggs and larvae to prevent infestation Treats, prevents, and controls lice infestations (dogs only) Safe and easy to apply Waterproof - remains effective even if pet gets wet (use of a soap-free shampoo is recommended)
Answered by: Cherley Petmeds Pro
Date published: 2016-09-08

I've been using cat advantage 2 and it's not killing all the fleas. I think he's immune to it. 

Asked by: Spooky
So sorry to hear that. Please email us at customerservice@1800petmeds.com or call us at 1-800-738-6337 so we can further assist you.
Answered by: Cherley Petmeds Pro
Date published: 2016-09-08

Can this be used on 4 month old puppy, 3 lbs?

Asked by: Rickles
Yes, this product is safe for Dogs (3 lbs or over and 7 weeks of age or older), Cats (2 lbs or over and 8 weeks of age or older), Ferrets (1 lb or over and 10 weeks of age or older)
Answered by: Cherley Petmeds Pro
Date published: 2016-09-08

Will I need a prescription for this medication?

Asked by: Charlie
No, this product is over the counter.
Answered by: Cherley Petmeds Pro
Date published: 2016-09-08

I'm buying for my puppy that is 8lb, but growing rapidly.  I would think she will outgrow the 2-10 lb dosage before we could use it all.  Should I purchase smaller or heavier weight dosage?

Asked by: Cocoloco
Since your furry baby is growing rapidly, we recommend purchasing a single dose of the smaller weight range from your veterinarian, since we do not sell single doses. You may purchase the higher dose with us so you can have that available for your furry baby when she gets to the heavier weight range.
Answered by: Cherley Petmeds Pro
Date published: 2016-08-27

My 4 month old, 4 lb kitten was treated last night at 10 pm but I'm still seeing live fleas. What do you recommend?

Asked by: Msnard
It will take about 12 hours for Advantage II to take full effect. If you are still seeing fleas after a day, contact your vet for a possible alternative.
Answered by: paulpharmacistintern
Date published: 2016-08-17
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