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Monthly heartworm and flea prevention in one easy topical application.
 
  • Prevents heartworm disease
  • Kills fleas and treats flea infestations
  • Treats and controls hookworms and roundworms
  • Treats and controls whipworms (Dogs)
  • Treats and controls ear mite infestations (Cats)
  •  
     
     

    Advantage Multi

     
    Q & A
    Starts at $92.99 Ships in one business day or less
    1_Select a Weight
      Dogs:





      Cats:


     
     
     
      Product Info   How to use   Ingredients   Customer Reviews   Q & A  

    What is Advantage Multi for Dogs and Cats?

    Advantage Multi for is a once a month topical application that contains a combination of the insecticide (imidacloprid) and the parasiticide (moxidectin). Advantage Multi for Dogs is used for the prevention of heartworm and the treatment and control of flea infestations, hookworms, roundworms and whipworms. Advantage Multi for Cats is used for the prevention of heartworm and the treatment and control of fleas infestations, roundworms, hookworms and ear mites. Adavantage Multi for Cats is also the first and only approved product to to kill adult fleas, treat flea infestations and prevent heartworm disease in ferrets. Advantage Multi requires a prescription from your veterinarian.
    Advantage Multi for Dogs and Cats

    For:
    Dogs (7 weeks of age or older and weighing at least 3 lbs)
    Cats (9 weeks of age or older and weighing at least 3 lbs)
    Ferrets (weighing at least 2 lbs)

    Benefits:
    Prevents heartworms, roundworms, hookworms in dogs and cats as well as whipworms in dogs and ear mites in cats
    Prevents heartworm disease, kills adult fleas and treats flea infestations in ferrets
    Easy, once a month, application
    Canine customers often purchase Preventic collars (sold separately) for tick protection

    How it works:
    The active ingredient moxidectin is used for the prevention and control of heartworms and intestinal worms by disrupting nerve transmission resulting in the paralysis and death of the parasite. The active ingredient imidacloprid, acts on the nervous system of the flea to cause paralysis and subsequent death.

    Cautions:
    Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become more severe, consult a veterinarian immediately. Safety has not been established in breeding, pregnant, or lactating dogs.


    More Information:
    Brand Name
    Advantage Multi (Bayer)
    Generic Name
    Imidacloprid, Moxidectin

    What is the most important information I should know about Advantage Multi for Dogs and Cats:
    Advantage Multi for Dogs is available in the following concentrations; Advantage Multi 9 containing imidacloprid 40mg and moxidectin 10mg in 0.4ml tubes for dogs 3-9 lbs, Advantage Multi 20 containing imidacloprid 100mg and moxidectin 25mg in 1 ml tubes for dogs 9.1 to 20 lbs, Advantage Multi 55 containing imidacloprid 250mg and moxidectin 62.5mg in 2.5ml tubes for dogs 20.1-55 lbs, Advantage Multi 88 containing imidacloprid 400mg and moxidectin 100mg in 4 ml tubes for dogs 55.1 to 88 lbs, and Advantage Multi 110 containing imidacloprid 500mg and moxidectin 125mg in 5 ml tubes for dogs 88.1 to 110 lbs. For dogs over 110 lbs use the appropriate combination of Advantage Multi for dogs tubes. Advantage Multi for Cats is available in the following concentrations; Advantage Multi 5 containing imidacloprid 23mg and moxidectin 2.3mg in 0.23ml tubes for cats 2 to 5 lbs, Advantage Multi 9 containing imidacloprid 40mg and moxidectin 4mg in 0.4ml tubes for cats 5.1 to 9 lbs, and Advantage Multi 18 containing imidacloprid 80mg and moxidectin 8mg in 0.8ml tubes for cats 9.1 to 18 lbs. For cats over 18 lbs use the appropriate combination. Children should not come in contact with the application site for 30 minutes after application.
     
    What is Advantage Multi:
    Advantage Multi for Dogs and Advantage Multi for Cats contain a combination of insecticide (imidacloprid) and endectocide (moxidectin) used for the prevention of heartworm disease and the treatment and control of flea infestations, hookworms, roundworms and whipworms in dogs and for the prevention of heartworm disease and the treatment and control of flea infestations, roundworms, hookworms, and ear mites in cats. Advantage Multi for Cats is now the first and only product indicated to kill adult fleas, treat flea infestations and prevent heartworm disease in ferrets.
     
    What should I discuss with my veterinarian before applying Advantage Multi for Dogs and Cats:
    Tell your veterinarian if your pet is breeding, pregnant or lactating since safe use of this product in these animals has not been determined. Do not use in animals allergic to Advantage Multi or either of the individual ingredients, imidacloprid (Advantage, K9 Advantix) or moxidectin (ProHeart).
     
    How should this medication be used:
    Advantage Multi is applied topically to the skin. It is not given by mouth. Follow the manufacturer's directions for application. Do not apply to irritated skin. Apply each dose once a month, every 30 days. If you do not understand the directions, or if you have difficulty applying the medication, contact your pharmacist or veterinarian. Store Advantage Multi for Cats at temperatures between 39ļ F and 86ļ F, avoiding excess heat or cold.
     
    What happens if I miss giving a dose:
    Apply the missed dose as soon as you remember. If it is almost time to apply the next dose, skip the missed dose and apply the next dose as directed. Do not apply 2 doses at once.
     
    What happens if I overdose the pet:
    Seek emergency veterinary medical treatment. Symptoms of overdose may include depression, increased salivation, tremors, or incoordination.
     
    What should I avoid when applying Advantage Multi for Dogs and Cats:
    Always follow the dosage instructions provided by your veterinarian. Do not use in dogs under 7 weeks of age or less than 3 lbs. Do not use in cats under 9 weeks of age or less than 2 lbs. Do not use Advantage Multi for Cats in ferrets under 2 lbs. Do not use on animals that are sick, debilitated, or underweight. Do not use Advantage Multi for Dogs on a cat. Do not use Advantage Multi for Cats on a dog. Do not allow any animal to lick the application site for 30 minutes. Separation of treated animals may be necessary. Children should not come in contact with the application site for 30 minutes after application. Advantage Multi can cause eye irritation and be harmful if swallowed. Wash hands thoroughly with soap and water after handling.
     
    What are the possible side effects of Advantage Multi Dogs and Cats:
    If any of the following serious side effects occur, stop using Advantage Multi and seek emergency veterinary medical attention; an allergic reaction (facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma). Contact your veterinarian if your dog shows scratching, rubbing, licking the application site; lethargy, decreased appetite, or hyperactivity. Contact your veterinarian if your cat shows lethargy and prolonged periods of sleep; behavioral changes including agitation, excessive grooming, hiding, pacing, etc.; discomfort at the application site (rubbing, scratching, etc.); increased salivation within 1 hour of treatment; increased drinking; or coughing. A medicinal odor and residue at the application site may also be seen. If the dog or cat ingests the product or licks the application site, serious adverse effects may occur including depression, salivation, incoordination, panting and tremors. Hair may appear stiff, matted oily, or damp after application. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.
     
    What other drugs will affect Advantage Multi for Dogs and Cats:
    Talk to your veterinarian or pharmacist regarding any other medications, including vitamins and supplements, and other flea and tick products your pet is using.

    Directions:
    Advantage Multi for Dogs and Advantage Multi for Cats are prescription medications used for the prevention of heartworm disease.
    Advantage Multi for Dogs is used in dogs for the treatment and control of flea infestation, hookworms, roundworms, and whipworms.
    •; Advantage Multi for Cats is used in cats for the treatment and control of flea infestation, roundworms, hookworms, and ear mites.
    •; Advantage Multi for Cats is also the first and only approved product to to kill adult fleas, treat flea infestations and prevent heartworm disease in ferrets.
    Tip: For the first 30 minutes after application ensure that dogs and cats cannot lick the product from the application sites. Separate treated pets from one another and from other pets to reduce the risk of accidental ingestion. Wash hands with soap and water after handling. Do not let children touch the treated pet's skin for at least 30 minutes after applying the product. Do not get these products in the pet's mouth or eyes.
    Dosage:

    Pet Weight Dosage
    Dogs/Puppies:
    (7 weeks of age or older)
    3-9 lbs While your dog is standing, apply Advantage Multi-9 for Dogs topically by parting the hair on the back of the dog between the shoulder blades until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. Apply each dose once, every 30 days
    9.1-20 lbs While your dog is standing, apply Advantage Multi-20 for Dogs topically by parting the hair on the back of the dog between the shoulder blades until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. Apply each dose once, every 30 days
    20.1-55 lbs While your dog is standing, apply Advantage Multi-55 for Dogs topically by parting the hair on the back of the dog between the shoulder blades until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Apply each dose once, every 30 days
    55.1-88 lbs While your dog is standing, apply Advantage Multi-88 for Dogs topically by parting the hair on the back of the dog between the shoulder blades until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Apply each dose once, every 30 days
    88.1-110 lbs* While your dog is standing, apply Advantage Multi-110 for Dogs topically by parting the hair on the back of the dog between the shoulder blades until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Apply each dose once, every 30 days
    Cats/Kittens:
    (9 weeks of age or older)
    2-5 lbs Apply Advantage Multi-5 for Cats topically by parting the hair on the back of the cat's neck at the base of the head until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift the tube away from the skin before releasing pressure on the tube. Apply each dose once, every 30 days
    5.1-9 lbs Apply Advantage Multi-9 for Cats topically by parting the hair on the back of the cat's neck at the base of the head until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift the tube away from the skin before releasing pressure on the tube. Apply each dose once, every 30 days
    9.1-18 lbs** Apply Advantage Multi-18 for Cats topically by parting the hair on the back of the cat's neck at the base of the head until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift the tube away from the skin before releasing pressure on the tube. Apply each dose once, every 30 days
    Ferrets:

    2-4.4 lbs Apply Advantage Multi-9 for Cats topically by parting the hair on the back of the ferret's neck at the base of the head until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift the tube away from the skin before releasing pressure on the tube. Apply each dose once, every 30 days
    Horses:

    Storage: Should be stored at room temperature between 39 F and 86 F, avoiding excess heat or cold.
    *For dogs over 110 lbs use the appropriate combination.
    **For cats over 18 lbs use the appropriate combination.

    Advantage Multi 9 for Dogs 3-9 lbs:
    Active Ingredients Amount
    Imidacloprid 40 mg
    Moxidectin 10 mg

     

    Advantage Multi 20 for Dogs 9.1-20 lbs:
    Active Ingredients Amount
    Imidacloprid 100 mg
    Moxidectin 25 mg

     

    Advantage Multi 55 for Dogs 20.1-55 lbs:
    Active Ingredients Amount
    Imidacloprid 250 mg
    Moxidectin 62.5 mg

     

    Advantage Multi 88 for Dogs 55.1-88 lbs:
    Active Ingredients Amount
    Imidacloprid 400 mg
    Moxidectin 100 mg

     

    Advantage Multi 110 for Dogs 88.1-110 lbs:
    Active Ingredients Amount
    Imidacloprid 500 mg
    Moxidectin 125 mg

     

    Advantage Multi 5 for Cats 2-5 lbs:
    Active Ingredients Amount
    Imidacloprid 23 mg
    Moxidectin 2.3 mg

     

    Advantage Multi 9 for Cats 5.1-9 lbs:
    Active Ingredients Amount
    Imidacloprid 40 mg
    Moxidectin 4 mg

     

    Advantage Multi 18 for Cats 9.1-18 lbs:
    Active Ingredients Amount
    Imidacloprid 80 mg
    Moxidectin 8 mg
    Advantage Multi 4.1 5 204 204
    Multi Advantage By combining imidacloprid and moxidectin, advantage multi offers the wonderful benefit of broad protection against BOTH common internal and external parasites in dogs and cats. An important area of coverage includes not only adult stages, but the immature stages of roundworms and hookworms, two parasites that are a risk to people if not prevented in our pets. It also treats and controls, and prevents whipworms, which are difficult to eradicate in both dogs and the environment. When applied monthly, it is almost 100 percent effective in preventing heartworm disease in dogs and cats. Additional benefits of treating scabies and demodectic mange and ear mites make this a very attractive product. All of this with the wonderful flea control benefits of the product advantage. The greatest benefit I see with this versatile product is that it takes the labor out of administering a myriad of medications to dogs to control these varied internal and external parasites. I also find that it kills the larval stages of fleas in the home surroundings of treated pets, which is a wonderful added benefit. I have on rare occasions seen topical irritation and sensitivity at the site of application, and even more scarse neurological reactions in hypersensitive pets. The only other downside would be the potential high cost of this product, as well as the need for clients to obtain a prescription from their veterinarian. Overall, however, I have found this product to be an excellent and safe all around internal and external parasite control manager in our dogs and cats. 06/16/2008
    advantage multi this product is very effective , thank goodness as both Mommykitty and Slate sleep on the bed with me. my only problem is trying to outsmart my cats ability to read the calendar and know when it is time to apply the topical solution... They head for the hills as soon as they hear me open the cabinet door where all the pet meds are kept.. My vet tells me it is the very cold-like sensation that they do not like... Well , I guess it would be like an ice cube pressed to our neck.. 08/11/2014
    DOES NOT WORK! I live in SD and had my 4lb Chihuaha on a topical flea only product (I think it was Advantage). Then my vet suggested he go to this with the heartworm in it. I put one does on exactly on the 15th of the month and 10 days into this product I had over 15 flea bites on MY BODY and found 3 fleas on him in one day. The rep from Advantage INSISTED these were not fleas (DUH) that once a flea lands it doesn't have to bite to die....my dog never had a flea on him until I switched to this product. I called my new vet and they said topical flea meds are not working in the SD area. Only oral work I discontinued it's use. It is not a good product out here. 08/04/2014
    Seems to work I use this product for the heartworm prevention. My dog gets diarrhea when I give him heartguard and is sick for two days. He doesn't really like this either. Definite lethargy and seems pretty down as soon as I put it on him (2 months in a row now). However, its better than the reaction to heartguard. He's a 20 lb Pug/Boston Terrier mix. I supplement the Advantage multi with Frontline for tick prevention, so I can't attest to Advantage Multi's flea prevention capabilities. He gets AdMul on 1st of the month and Frontline on the 15th. While he doesn't enjoy the Frontline either, he doesn't get lethargic when I use it 07/02/2014
    not sure if this product is for me It has only been a couple of weeks since I applied the advantage multi. Since I have another dog, BayB I plan on using that for both. After application both dogs behaved as if they were ill. There was some vomiting and lethargy. The verdict is not yet in. Next month will provide a clearer picture. 06/23/2014
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    209 Questions · 270 Answers

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    2 weeks, 4 days ago
    by
    liza
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    Answer: 
    Yes, Advantage Multi comes in a 6 pack which is a 6 month supply.
    2 weeks, 3 days ago
    by
    Cheryl-Pharmacist
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    4 weeks, 1 day ago
    by
    Anonymous
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    Answer: 
    Seizures can be a possible side effect of Advantage Multi. Your veterinarian will determine if this product is appropriate for your pet. Medical treatment should be sought if your pet has experienced a seizure.
    3 weeks, 4 days ago
    by
    Lisa M
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    I have been using Advantage Multi for our dog and last administered 1 week ago. We are going to the mountains in a few days and I realized that tick prevention is not covered with this. Is it safe to use the Seresto collar in conjunction with Advantage Multi so he has tick protection?
    1 month ago
    by
    CharliesMom
    Murrieta, CA
    Answer this question

    Answers

    Answer: 
    Thank you for your question. Please consult with the vet as that would be a double dose of flea medication. We have a Preventic collar that protects only against ticks which you can definitely use.
    1 month ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    And have been consistent all along except this one - how protected is my dog ? She has come into contact with an infected dog with whip worm. I am praying that my dog is ok.....
    1 month ago
    by
    Jerrie
    Plano, Tx
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    Answer: 
    if you missed the dose by just a few days or even up to a week, there would be some protection.However if you missed an entire month, there is a chance of your dog being infected. I hope he is okay too :). I have to be honest with you though.....the veterinarian should be told and may want to test for whipworms.
    1 month ago
    by
    Linda M 1800petmeds pharmacist
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    My 14 pound shih tzu is being treated for allergies or infestation of yeast or a bacteria to stop his scratching and chewing his skin until he bleeds. The dermatologist gave him a perscription for Advantage Multi 9-20lbs and instructed us to apply it to him and our other two shih tzu every two weeks. Since it is normally applied once a month is every two weeks too often?
    1 month, 1 week ago
    by
    Mel
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    Answer: 
    I have a barely 4 lbs yorkie being treated for allergies, and he has to use this weekly. This is what the vet recommended.
    1 month ago
    by
    vtufo
    Houston
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    Answer: 
    There are times when using the product every 2 weeks must be done to clear up a problem. Hopefully your pets issue will clear up and you can go back to 1 time a month
    1 month ago
    by
    Linda M 1800petmeds pharmacist
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    This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
    Note: Any trademarks are the property of their respective companies.
     
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