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Advantage II

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Advantage II?

Advantage II is a monthly flea preventative for dogs and cats that offers comprehensive flea protection by killing adult fleas, larvae, and eggs. Plus, it kills fleas through contact, which means fleas don't have to bite your pet to die. Advantage II also treats, prevents, and controls lice on dogs. Advantage II does not kill ticks, so we recommend using the Preventic Tick Collar along with Advantage II (dogs only). Advantage II for small cats 5-9 lbs can also be used for ferrets weighing 1 lb or over and 10 weeks of age or older.

For:

Dogs (3 lbs or over and 7 weeks of age or older), Cats (2 lbs or over and 8 weeks of age or older), Ferrets (1 lb or over and 10 weeks of age or older)

Benefits:
  • Convenient, once-a-month application
  • Kills through contact - fleas don't have to bite to die
  • Kills fleas within 12 hours of application on cats and dogs
  • Kills fleas within 24 hours of application on ferrets
  • Kills all flea life stages including flea eggs and larvae to prevent infestation
  • Treats, prevents, and controls lice infestations (dogs only)
  • Safe and easy to apply
  • Waterproof - remains effective even if pet gets wet (use of a soap-free shampoo is recommended)
How it Works:

The first active ingredient is imidacloprid, which acts on the nervous system of the flea to cause paralysis and subsequent death. Within 12 hours of application on cats and dogs, 98-100 percent of fleas are dead. Advantage II Small Cat kills the existing fleas on ferrets within 24 hours. The second active ingredient, pyriproxyfen, is an insect growth regulator. Once a female flea lays her eggs, pyriproxyfen works to prevent the eggs from hatching, ending the flea life cycle. Also, the active ingredient in Advantage II kills through contact, which means that fleas don't have to bite your pet to die. Reinfesting fleas are killed with protection against further flea infestation lasting for up to 4 weeks. Pre-existing pupae in the environment may continue to emerge for 6 weeks or longer depending upon the climactic conditions.

Cautions:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become severe, consult a veterinarian immediately. Do not get this product in your pet's eyes or mouth.

Brand Name:

Advantage II (Bayer)

Active Ingredient(s):

Imidacloprid (9.1%), Pyriproxyfen (0.46%) Other ingredients (90.44%)

What is this product used for:

Advantage II Kitten, Advantage II Small Cat and Advantage II Large Cat are once a month topical flea prevention and treatment for cats and kittens over 8 weeks or older. Advantage II Small Cat may also be used for ferrets weighing 1 lb or over and 10 weeks of age or older. Advantage II Small Dog, Advantage II Medium Dog, Advantage II Large Dog, and Advantage II Extra Large Dog are once a month topical flea prevention and treatment for dogs and puppies 4 lbs or more and 7 weeks or older. Advantage II kills all flea life stages. Advantage II kills fleas within 12 hours of application. Advantage II for Dogs also treats, prevents, and controls lice infestations. Advantage II is waterproof and fragrance free.

Availability:

Advantage II for cats or ferrets and Advantage II for dogs are non-prescription (OTC) products.

How this product should be used:

Advantage II Kitten is available in 0.23 ml applicators for kittens 2-5 lbs (turquoise). Advantage II Small Cat is available in 0.4 ml applicators for cats 5-9 lbs or ferrets weighing 1 lb or over and 10 weeks of age or older (orange). Advantage II Large Cat is available in 0.8 ml applicators for cats 9 lbs & up (purple). Advantage II Small Dog is available in 0.4 ml applicators for dogs 3-10 lbs (green). Advantage II Medium Dog is available in 1.0 ml applicators for dogs 11-20 lbs (teal). Advantage II Large Dog is available in 2.5 ml applicators for dogs 21-55 lbs (red). Advantage II Extra Large Dog is available in 4.0 ml applicators for dogs over 55 lbs (blue). To apply, place the applicator tip through your pet's hair to the skin level. On cats and ferrets, apply to skin on neck at the base of the skull. For dogs up to 20 lbs, apply to skin on back between the shoulder blades. For dogs 21 lbs or over apply the contents of one tube to 3 or 4 spots along the skin on back from the shoulder to the tail. Do not get this product in the pet's eyes or mouth.

What are the side effects:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become more severe, consult a veterinarian immediately.

What special precautions are there:

Advantage II is for external use on dogs and puppies 3 lbs or more and 7 weeks or older, cats and kittens 2 lbs or more and 8 weeks or older, or ferrets weighing 1 lb or over and 10 weeks of age or older. Consult a veterinarian before using on medicated pets, if the pet is being given this product along with other pesticides, and debilitated, aged, pregnant or nursing pets. This product causes eye irritation in humans and is harmful if swallowed. Avoid contact with skin. Call poison control center if swallowed. If on skin, wash with plenty of soap and water. If in eyes, flush with plenty of water.

In the event of overdose:

Contact your veterinarian or veterinary emergency room.

How should I store this product:

Store this product in a cool dry place. Do not store in the refrigerator. Do not reuse empty container. Do not contaminate water, food or feed by storage or disposal. To dispose of empty container place in trash or offer for recycling if available. If container is partly filled call local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain. Keep out of reach of children and pets.

How to Use
Directions:
  • Only use Advantage II on dogs/puppies over 3 lbs and over 7 weeks of age, cats/kittens over 2 lbs and over 8 weeks of age, and ferrets 1 lb or over and 10 weeks of age or older.
  • Apply Advantage II once a month every month.
  • For dogs up to 20 lbs, part the pet's hair between the shoulder blades until you can see the skin. Place the tip of the applicator on the skin and release all of the tube's contents on a single spot directly on the skin.
  • For dogs 21 lbs and over, apply entire contents of the tube evenly in 3 or 4 spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the applicator on the skin and release a portion of the Advantage II solution directly on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog.
  • For kittens, cats and ferrets, place the applicator tip through the cat's hair to the skin on the neck at the base of the skull and release all of the tube's contents on a single spot directly on the skin.
  • Use only one applicator per treatment.
Tip:

Under normal conditions Advantage II is effective for a month. However, in case of severe flea infestation, retreatment may be necessary earlier than four weeks. Do not re-treat cats or dogs more often than once every 7 days. For ferrets, do not retreat more often than every 14 days. After flea control is obtained, return to a monthly treatment.

Dosage:
Dogs/Puppies: (7 weeks of age or older)
Weight
Dosage
3-10 lbs
Apply contents of 1 applicator once a month (Green Box)
11-20 lbs
Apply contents of 1 applicator once a month (Teal Box)
21-55 lbs
Apply contents of 1 applicator once a month (Red Box)
Over 55 lbs
Apply contents of 1 applicator once a month (Blue Box)
Kittens: (8 weeks of age or older)
Weight
Dosage
2-5 lbs
Apply contents of 1 applicator once a month (Turquoise Box)
Cats: (8 weeks of age or older)
Ferrets: (1 lb or over and 10 weeks of age or older)
Weight
Dosage
Ferrets 1+ lbs
Apply contents of 1 applicator once a month (Orange Box)
5-9 lbs
Apply contents of 1 applicator once a month (Orange Box)
9 lbs & up
Apply contents of 1 applicator once a month (Purple Box)
Horses:
Do not use!
Storage:

Should be stored in a cool dry place. Do not refrigerate.

Ingredients
Advantage II for Kittens 2-5 lbs (Kitten - Turquoise Box) (0.23 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Cats 5- 9 lbs or Ferrets 1 lb or over and 10 weeks of age or older (Small Cat - Orange Box) (0.4 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Cats Over 9 lbs (Large Cat - Purple Box) (0.8 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 3 to 10 lbs (Small Dog - Green Box) (0.4 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 11 to 20 lbs (Medium Dog - Teal Box) (1.0 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 21 to 55 lbs (Large Dog - Red Box) (2.5 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Advantage II for Dogs 55 lbs and Over (Extra Large Dog - Blue Box) (4.0 mL):
Active Ingredients
% By Weight
Imidacloprid
9.10%
Pyriproxyfen
0.46%
Other Ingredients (not specified)
90.44%
Customer Reviews
Advantage II is rated 4.2427 out of 5 by 2,826.
Rated 5 out of 5 by from Great Product Purchased this for my 4 cats, great product, after 1 day I noticed no more fleas or flea droppings on my two 8 month olds and the 1 cat I have outside quit scratching after a few days, will definitely be purchasing again. Cats didn't have any side effects to the medicine, the product does spread a little in the area so it's best to place a little higher up where the cat cannot lick the medicine.
Date published: 2017-01-11
Rated 5 out of 5 by from works i have been using advantage for years on my dog and cats it is well worth the price
Date published: 2016-12-31
Rated 5 out of 5 by from Great stuff This is a great product that works !
Date published: 2016-12-29
Rated 5 out of 5 by from Works Great I have been using Advantage II for years and it works wonderfully....
Date published: 2016-12-28
Rated 5 out of 5 by from After treating my kitty cat Soffie with Advantage ll the vary next morning all her flea's were gone. I'm not joking " they were gone " . Thank you, 1-800-PetMed
Date published: 2016-12-19
Rated 5 out of 5 by from No fleas ever! I have been isomer Advantage II with my yellow labs for several years and have never had a problem with fleas. I thank you for preventive scratching and aggravation to my pups.
Date published: 2016-12-17
Rated 5 out of 5 by from BEST EVER All 6 of my cats have used this product for over 7 years....FANTASTIC....NO FLEAS...All year long...my cats go in and out...no adverse effects either....please consider purchasing this product...
Date published: 2016-12-17
Rated 5 out of 5 by from great product vet approved my vet says this was the best and it is.. I put on my lab every two weeks due to us living in hot climate, Louisiana.. and my dog has not seen a flea since doing this as well as treating my yard and home after the massive flood we just had .. I will order here all the time. Janet Lentz
Date published: 2016-12-05
  • 2017-01-16T06:08CST
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Q&A

Why can't I get a 6 pack

Asked by: Donna
The 6pk of this product is currently in stock. If you need assistance placing your order please let us know.
Answered by: Amy Petmed Pro
Date published: 2017-01-13

How long shelf life if unopened?

Asked by: Kiki
The Advantage II does not expire.
Answered by: Cherley Petmeds Pro
Date published: 2017-01-06

What's the difference between advantage & advantage II?

Asked by: Debbie
Advantage II contains an insect growth regulator (Pyriproxyfen) to kill all life stages of fleas.
Answered by: Amy Petmed Pro
Date published: 2017-01-03

I have 2 large cats over 9lbs, what's the difference between advantage & advantage II?

Asked by: Debbie
Advantage II contains an insect growth regulator (Pyriproxyfen) to kill all life stages of fleas.
Answered by: Amy Petmed Pro
Date published: 2017-01-03

I have 4 cats...2 weigh 6lbs and 2 are 15lbs...if i buy the 3 pack can I use one tube for my two small cats?

Asked by: Auntifrances
Each cat should use the weight specific medication. It is difficult to measure out the proper dose from the tubes.
Answered by: 1800Petmeds Pharmacist
Date published: 2016-12-21

I use this on my dog. I just got a cat. Is it ok for the cat to be around this medication?

Asked by: Nancy
This product is also sold for cats, so it is not harmful to them. However since the Advantage II is pet specific, I would advise to make sure the product is completely dry before allowing them to interact.
Answered by: Amy Petmed Pro
Date published: 2016-12-20

Is the product Advantage II FDA approved?

Asked by: morty6
Yes, it is approved to sell in the US.
Answered by: Carolyn Petmed Pro
Date published: 2016-12-15

I have a dog that weighs over 100 pounds. he is closer to150lbs. does that mean I use 3 applications of the advantage II ? Thank you in advance. :)

Asked by: stasia1067
You may use one dose for dogs 55 lbs and over. This dose covers pets up to 200 lbs.
Answered by: Cherley Petmeds Pro
Date published: 2016-12-15
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