Acepromazine is a phenothiazine tranquilizer that is used prior to anesthesia and surgery because of its sedative effects and its ability to prevent vomiting. It's also used as an aid in controlling excited animals during examinations, treatments, and grooming. Acepromazine requires a prescription from your veterinarian, and is sold per tablet.
For: Cats and Dogs
An effective tranquilizer
Controls overly excitable animals
Can prevent vomiting post-surgery
Sold affordably per tablet
How it works:
Acepromazine is classified as a phenothiazine neuroleptic, which means it modifies the chemicals in your pets brain to change their behavior. Its a tranquilizer that depresses the central nervous system. The mechanism of action is not exactly known, however, its thought to block receptors of dopamine in the brain, a chemical used for cell-to-cell communication.
Tell your veterinarian if your pet has liver disease, heart disease, seizure disorders, or if the pet is pregnant or lactating. You should also mention other CNS (Central Nervous System) medications such as clomipramine, fluoxetine, and Reconcile or monoamine oxidase inhibitors such as Anipryl, Selegiline, or Preventic Collar that you are giving or using on your pet.
Brand Name Aceproject (Vetus), Aceprotabs (Vetus), PromAce (Fort Dodge)
Generic Name Acepromazine (ace PRO ma zeen)
What is the most important information I should know about Acepromazine: Acepromazine is a prescription medicine FDA approved for veterinary use in dogs only; however it is a commonly accepted practice for veterinarians to use acepromazine in cats. Acepromazine is available as 10mg and 25mg tablets. Each tablet is quarter scored. The usual dose for dogs and cats is 0.25-1 mg/lb. Acepromazine may color the urine pink. Occasionally, this medication may have an opposite effect causing stimulation, therefore this medication should not be used to treat aggression.
What is Acepromazine: Acepromazine is a phenothiazine tranquilizer used by veterinarians as an aid in tranquilization and before using anesthesia. Acepromazine may also be used for purposes other than those listed.
What should I discuss with my veterinarian before giving acepromazine to my pet: Tell your veterinarian if your pet has liver disease, heart disease, seizure disorders or if the pet is pregnant or lactating. Also mention other CNS medications, such as Phenobarbital, that your pet may be taking.
How should this medication be given: Give this medication exactly as directed by your veterinarian. Acepromazine should be given 45 minutes to 1 hour prior to the procedure for the medication to take effect. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store acepromazine at room temperature, away from moisture and heat.
What happens if I miss giving a dose: Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.
What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include excess drowsiness, slow heart rate and breathing, unsteady movement, unconsciousness, low blood pressure or seizures.
What should I avoid while giving acepromazine to my pet: Do not give your pet epinephrine or CNS depressant medications such as Phenobarbital.
What are the possible side effects of acepromazine: Stop giving acepromazine and seek emergency veterinary medical care in the event of rare allergic reaction (difficulty breathing; swelling of the lips; tongue; or face; or hives). Other, less serious side effects that have been reported but may resolve with continued treatment. Continue to give acepromazine and notify your veterinarian if your pet show signs of sedation, depression, incoordination, low blood pressure, slower heart rate and breathing. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.
What other drugs will affect acepromazine: Before giving acepromazine, tell your veterinarian if your pet is being given phenytoin, antiarrhythmics such as quinidine and beta blockers such as propranolol. Antidiarrheal medications and antacids may reduce the effectiveness of acepromazine.
Where can I get more information: Your pharmacist has additional information about acepromazine written for health professionals that you may read.
Acepromazine is a prescription tranquilizer use by veterinarians in dogs and cats.
Acepromazine is typically used prior to anesthesia and surgery because of its sedative effects and because it can prevent vomiting.
It is also used as an aid in controlling excited animals during examination, treatment, and grooming.
Tip: Acepromazine may color the urine pink. Occasionally, this medication may have an opposite effect causing stimulation; therefore this medication should not be used to treat aggression.
Give 0.25–1 mg per pound of pet’s body weight by mouth. Should be given 45 minutes to 1 hour prior to the procedure
Storage: Should be stored at room temperature. Keep away from moisture and heat.
Active Ingredient (per tablet)
I have a very hyper dog that both knees had to have surgery. "Rupture anterior cruciate ligament with a torn medial meniscus". Before and after surgery he has to be in his crate for 24/7. Without Acepromazine not sure how he could cope with being in that crate. Does not get out of his crate until around August.
Yet Acpromazine does not slow him down when people come over or he is excite, other than that thank goodness he is sleeping . No side effect for this guy. Can't wait until he is back running around and off all of these meds that he has been taking since Jan. 2011
Great for flying
I gave my 6 lb., 8 month old puppy Kaity 2.5 mg. (1/4 tab) of Acepromazine 20 minutes prior to her first airline flight. She slept on my lap throughout most of the flight and was calm during our layover. The flight attendants on Southwest were great, and the other passengers on our row fell in love with her. They couldn't believe a puppy could be so well behaved. She had no side effects from the medication and once the sedation wore off she was her old playful self.
Product calmed her down.
Lulu is a Lab/pit mix and is approx. 65-70 lbs. She got frightened of having her nails clipped and she won't even let us touch her nails. We gave her two pills and were able to trim her nails without any problems. She acted drunk for awhile but came out of it her normal active self.
Great for surgery recovery
My six-month 25lb Border Collie puppy was spayed a few days ago and I was told to prevent her from running or jumping for at least one week. I had no idea how on earth I would possibly manage this, as she has hours and hours of full-speed dog park energy every day.
After research and talking with the vet I started with half of the lowest recommended dose. It worked like a charm for the first 48 hours, but then she started getting excited well before the six hour dose period was up. So I increased it from a quarter pill every six hours to a quarter pill every four hours. This worked great for a day, and then needed to up the dose to half a pill every six.
It has been two days on half a pill and while she will get up and try to play if the opportunity is there, as long as I keep the room quiet and keep her away from distractions she is still content to sleep for most of the duration of the dose. Eventually I may need to up the dose again, but it looks like she'll be fully healed long before we get to the point where we need the maximum dose.
Start low and slow, be patient and use this as an aid to a problem, not a cure-all.
p.s. For large breeds, herding dogs, and sight hounds - do some research first! Maybe get your dog tested for the MDR1 gene. And bigger dogs have a higher chance of blood pressure dropping too low.
My dog Rose petal was a puppy mill dog for six years.
She has been with me a year and has come a long way
learning to be a dog.
She becomes tramatized when I groom her.
This product is a God send-thank you
Acepromazine is a prescription medicine FDA approved for veterinary use in dogs only; however it is a commonly accepted practice for veterinarians to use acepromazine in cats. Please speak to your doctor for any of your medication needs.
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.