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What is the most important information I should know about Ursodiol: Ursodiol is a
prescription medication not FDA approved for use in animals; however, it is a commonly accepted
practice for veterinarians to use this medication in dogs and cats. Ursodiol is available as
300mg capsules. The usual dose for dogs and cats depends on the condition and the severity of
symptoms. Do not give over the counter antacids that contain aluminum, such as Maalox or
Mylanta unless your veterinarian approves. Aluminum may decrease the effectiveness of this
medication. Ursodiol may need to be taken for a long period of time. Do not stop giving
ursodiol to your pet unless told to by your veterinarian.
What is Ursodiol: Ursodiol decreases the amount of cholesterol
in bile and bile stones, by reducing the amount of cholesterol the liver produces. Ursodiol
reduces the amount of cholesterol that is absorbed from food and also increases the breakdown
of cholesterol, especially cholesterol that has formed into gallbladder stones. Ursodiol is not
used to treat gallstones that are calcified. Ursodiol may also be used for purposes other than
those listed in this guide.
What should I discuss with my veterinarian before giving Ursodiol to
my pet: Tell your veterinarian if your pet has cholecystitis, biliary obstruction,
gallstone pancreatitis or biliary-gastrointestinal fistula. Also tell your veterinarian if your
pet has any other medical conditions, especially heart, liver or kidney disease. Tell your
veterinarian if your pet is pregnant or lactating.
How should this medication be given: Give this medication
exactly as directed by your veterinarian. If you do not understand the directions ask the
pharmacist or veterinarian to explain them to you. Allow pet to drink plenty of water. Store
Ursodiol at room temperature, away from moisture and heat. Keep this medication away from
children and pets.
What happens if I miss giving a dose: Give the missed dose as
soon as you remember. However, if is almost time for the next regularly scheduled dose, skip
the missed dose and take the next one as directed. Do not give a double dose of the
medication.
What happens if I overdose the pet: Seek emergency veterinary
medical treatment. Symptoms of ursodiol overdose are unknown but may include diarrhea.
What should I avoid while giving Ursodiol to my pet: You should
avoid giving your pet any over the counter antacids that contain aluminum. Examples include
Maalox or Mylanta.
What are the possible side effects of Ursodiol: If any of the
following serious side effects occur, stop giving ursodiol and seek emergency veterinary
medical attention; an allergic reaction (difficulty breathing; swelling of the lips; tongue or
face; hives). Other less serious side effects may occur. Continue giving ursodiol and talk to
your veterinarian if your pet experiences nausea or upset stomach, diarrhea or headache. Other
side effects may also occur. Talk to your veterinarian about any side effect that seems unusual
or bothersome to the animal.
What other drugs will affect Ursodiol: Tell your veterinarian if
your pet is being given an antacid containing aluminum as this may decrease the amount of
ursodiol being absorbed. Estrogens (D.E.S. or diethylstilbesterol) may increase the amount of
cholesterol in the body which would decrease the effectiveness of Ursodiol. Drugs other than
those listed may also interact with Ursodiol. Talk to your veterinarian before giving your pet
any prescription or over the counter medicines.
Where can I get more information: Your pharmacist has additional
information about Ursodiol written for health professionals that you may read.
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