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Sulfamethoxazole and Trimethoprim Tablets Double Strength

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Sulfamethoxazole and Trimethoprim Tablets Double Strength?

Sulfamethoxazole and Trimethoprim (SMZ/TMP) Tablets Double Strength is a sulfonamide combination used to treat respiratory, urinary tract, skin, or gastrointestinal infections, and other conditions. Sulfamethoxazole and Trimethoprim Tablets Double Strength require a prescription from your veterinarian, and are sold per tablet.

For:

Cats and Dogs

Benefits:
  • Effective against a wide array of bacterial infections in dogs and cats
  • Simple once-a-day dosing
How it Works:

Sulfamethoxazole is a sulfonamide antibiotic that limits the growth of bacteria. Sulfonamides inhibit synthesis of folic acid, important to bacterial DNA synthesis. Trimethoprim works by starving the bacteria of nucleotides necessary for DNA replication.

Cautions:

Do not use in pregnant or nursing animals. Leave plenty of water for your pet to drink. Report any unusual side effects to your veterinarian.

Brand Name:

Bactrim, Bactrim DS (Roche), Septra, Septra DS (Monarch)

Generic Name:

Sulfamethoxazole (SMZ) and Trimethoprim (TMP) (sulfa-meth-ox'-ah-zole with tri-meth'-o-prim)

What is the most important information I should know about Sulfamethoxazole and Trimethoprim Tablets Double Strength:

Sulfamethoxadole and Trimethoprim Tablets Double Strength is a prescription medication that is not FDA-approved for veterinary use; but it is commonly accepted practice for veterinarians to prescribe this medication for dogs and cats. Sulfamethoxazole and Trimethoprim Tablets Double Strength are available as scored tablets. The usual initial dose for dogs and cats is 13mg/pound every 24 hours, which may be divided into two doses given 12 hours apart. Always follow the dosage instructions provided by your veterinarian. Do not give Sulfamethoxazole and Trimethoprim Tablets Double Strength to any pet other than the pet for whom it was prescribed. Sulfamethoxazole and Trimethoprim Tablets Double Strength is not for use in animals allergic to it or other sulfa drugs.

What is Sulfamethoxazole and Trimethoprim Tablets Double Strength:

Sulfamethoxazole and trimethoprim are both antibiotics that treat different types of bacterial infections in the body such as urinary tract and ear infections (otitis), bronchitis, and certain types of diarrhea. This medication may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving Sulfamethoxazole and Trimethoprim Tablets Double Strength to my pet:

Tell your veterinarian if your pet has liver or kidney disease, G6PD (glucose-6-phosphate dehydrogenase) deficiency, or if your pet is pregnant or lactating.

How should this medication be given:

Give this medication exactly as directed by your veterinarian. The dose and duration of therapy will depend on the type of infection and the response to the medication. Give all of the medication your veterinarian has prescribed. Symptoms may start to improve before the infection is completely treated. Give Sulfamethoxazole and Trimethoprim Tablets Double Strength by mouth. The tablets may be given with food, and they can be crushed and put in food if needed. Allow plenty of water for your pet to drink. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Sulfamethoxazole and Trimethoprim Tablets Double Strength at room temperature away from moisture and heat. Keep this medication away from children and pets.

What happens if I miss giving a dose:

Give the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose the pet:

Seek emergency veterinary medical treatment. Symptoms of overdose may include nausea, vomiting, decreased appetite, diarrhea, yellowing of the eyes, decreased urine production, bloody urine, and coma.

What should I avoid while giving Sulfamethoxazole and Trimethoprim Tablets Double Strength to my pet:

Do not give this medication to pets allergic to it or other sulfonamides (sulfa drugs). Avoid prolonged exposure to sunlight. This medication may increase sensitivity of the skin to sunlight.

What are the possible side effects of Sulfamethoxazole and Trimethoprim Tablets Double Strength:

Stop giving the medication and seek emergency veterinary medical attention if your pet experiences an allergic reaction (difficulty breathing, closing of the throat, swelling of the lips, tongue or face, or hives), unusual bleeding or bruising, or yellow skin or eyes. Other less serious side effects may also occur. Continue to give the medication and talk to your veterinarian if your pet experiences fatigue, dizziness, nausea, vomiting, decreased appetite, diarrhea, weakness, or increased sensitivity to the sun. Side effects other than those listed may occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What other drugs will affect Sulfamethoxazole and Trimethoprim Tablets Double Strength:

Before giving this medication to your pet, tell your veterinarian if your pet is being given warfarin, aspirin, glipizide, or phenytoin. Drugs other than those listed may also interact with sulfamethoxazole and trimethoprim. Talk to your veterinarian or pharmacist before giving prescription or over-the-counter medications.

Where can I get more information:

Your pharmacist has additional information about Sulfamethoxazole and Trimethoprim Tablets Double Strength written for health professionals that you may read.

Call your veterinarian for medical advice about any side effects to your pet. You may report side effects to the FDA at 1-800-FDA-1088.

How to Use
Directions:
  • Sulfamethoxazole and Trimethoprim Tablets Double Strength are a broad-spectrum prescription antibiotic that is used in dogs and cats to treat respiratory infections such as bronchitis, urinary tract infections, skin infections, ear infections, gastrointestinal infections, and certain types of diarrhea.
  • Sulfamethoxazole and Trimethoprim Tablets Double Strength are not FDA-approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to prescribe this medication for dogs and cats.
  • Give this medication exactly as directed by your veterinarian.
Tip:

The dose and duration of therapy will depend on the type of infection and the response to the Sulfamethoxazole and Trimethoprim Tablets Double Strength.

Dosage:
Dogs/Cats:
Weight
Dosage
All weights
Give 13mg per pound of pet's body weight by mouth every 24 hours, which may be divided into two doses given 12 hours apart. You may crush the tablets and put them in food if needed. Allow plenty of water for your pet to drink.
Horses:
Do not use!
Storage:

Store at room temperature away from moisture and heat.

Ingredients
Sulfamethoxazole and Trimethoprim Tablets Double Strength:
Active Ingredients (per tablet)
Strength
Sulfamethoxazole
800 mg
Trimethoprim
160 mg
Customer Reviews
Sulfamethoxazole and Trimethoprim Tablets Double Strength is rated 2.875 out of 5 by 8.
Rated 3 out of 5 by from Decent job We actually had this prescribed for our horse. It worked well only problem was she hated eating it. (she hates needles and its safer for everyone in pills).
Date published: 2012-10-12
Rated 5 out of 5 by from SULFA/TRIM A Great Antibiotic! My 7 yr old G. Shep has cancer and developed a respiratory infection that would not go away. Tried Amoxicillin no real effect, Cipro stopped the infection from spreading but would not get rid of it and FINALLY Sulfa/Trim is working!!! can be given once or twice a day depending on dogs tolerance. 100 lb dog taking 1300 mg per day. Scooby did have vomiting on the 2nd day, Initial dose was given at night, he vomited food prior to 2nd dose. This is a powerful antibiotic and should be given with caution. For Scooby this drug is a life saver.
Date published: 2012-03-14
Rated 4 out of 5 by from It works, but use correct dosage After surgery for an aural hematoma, the vet prescribed SMZ/TMP, 960 mg twice per day. After 6 days on it, our 87-lb female experienced extreme fatigue, vomitng, and complete loss of appetite. She can barely stand up with a lot of help from us. The PetMeds dosage page recommends 13 mg per pound of body weight every 24 hours, for a dosage of 1131 mg. We were giving her 1920 mg each day, or 70% too much! I've nothing against SMZ/TMP (by coincidence, my wife is taking it now), but the vet neglected to adjust the dosage to our dog's weight. Yesterday the vet had me stop givng the drug to our dog, and she appears to be improving. Buyer beware: compare the prescription from the vet to the recommended dosage.
Date published: 2011-11-30
Rated 5 out of 5 by from You guys w/ the 1 stars are a bunch of idiots Ok first off, this drug is a highly effective antibiotic, and deserves at least 4 stars. Second, don't give an effective drug a bad review just because YOUR dog had an allergic reaction to it.(The vet prescribed it, not the drug companies, so go give your vet a bad review for bad judgment) The vast majority of dogs use this medication with success. Finally, drugs have side effects, EVERY SINGLE ONE. Know there are risks, and I'm sorry if your dog suffered or passed away, but coming on here telling everyone to "beware" of bactrim like it's the freaking anti-Christ is just plain ignorant. Guys, this is an effective antibiotic. It's the same deal with humans that are allergic to sulfa, but bactrim is still widely used. Why? because it's good!
Date published: 2011-05-03
Rated 1 out of 5 by from DANGER This drug was administered to my beautiful dog after he underwent knee surgery for a torn ACL. The photo attached was take the day we brought him home from his surgery. This drug evidently can cause severe reaction causing immune disease which can lead to death, 2 weeks after his surgery he was fighting for his life, a battle in which he lost. Please be aware of the danger of using this drug and ask your vet for alternitive medication for your beloved pet. You have to be your pets advocate, do not just assume the vet knows best.
Date published: 2009-07-13
Rated 3 out of 5 by from sulfamethoxazole/trimethoprim product review Sulfamethoxazole/trimethoprim product review: This long term and still widely used antibiotic has been prescribed by veterinarians and MD/s for decades. It was one of the earlier and more effective antibiotics used to treat infections of the prostate, skin, urinary tract and airways. However with the development of newer and safer antibiotics, I have found that I have used this antibiotic much less in my veterinary practice, because of both safer and more effective newer alternatives. In certain breeds like Dobermans and Labrador retrievers(although these can occur rarely in any breed), we can see immune mediated reactions leading to joint problems, and bone marrow suppression, which can result in fevers, secondary super infections and joint pain. Use of this drug can also lower thyroid measurements in treated dogs, thus sometimes leading vets to mistakingly diagnose low thyroid levels or hypothyroidism, which is a disease that pets are treated for life. A major advantage of this antibiotic still in modern veterinary medicine is in treating neurologic or brain infections, where this drug often reaches higher therapeutic levels than many other drugs. In years past, this drug was also the first choice in treating cats affected with an infection called toxoplasmosis, however newer drugs like clindamycin are now more widely used for this purpose in feline medicine. A big major advantage of this drug is that it is still relatively inexpensive compared to many other antibiotics . However, given the potential reactions and newer and safer alternatives in many case situations , I give this prescription antibiotic an overall rating/efficacy of a 2.5 with a taste/ease of use of a 4.
Date published: 2009-05-05
Rated 1 out of 5 by from If your pet has any problems after starting this drug make sure your vet considers allergies to the drug. My dog's doctors kept on saying his symptoms where from his cancer and never considered he maybe allergic to the sulfa, now I wonder and I will never know the truth because we had him euthansized.
Date published: 2009-04-10
Rated 1 out of 5 by from This ABX is killing my dog As I type this, my dog is in ICU and quarantine due to toxicity from this drug. It completely wiped out his immune system, and affected his liver. He is fighting for his life right now. He was not overdosed, the drug itself did this to him.
Date published: 2008-12-14
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Q&A

My dog has kennel cough and unfortunately I can't afford a vet so I read somewhere that dogs can take bactrim. Will it be safe for her to take 

Asked by: jlynn
It would depend on what caused the cough and also Bacrim requies a perscription. It would be best to contact a veterinarian to see what is causing the cough and prescribe a medication.
Answered by: paulpharmacistintern
Date published: 2016-08-06

What does H49 on sulfamethoxazole-TMP tablet mean?

the Rx does not have the mg dosage on the bottle. It only has H49. What is this?
Asked by: pom
That is the company's drug identifier that they have assigned to this particular medication.This is only for identification purposes .If the tablet was separated from the original prescription bottle it came in, then you could call the pharmacy where you purchased your pets medication and they would be able to identify the tablet by its color,shape and any markings on the tablet( in this case H49). Thanks for your question.
Answered by: Marty, Pharm. D.
Date published: 2015-11-18

smz-tmp, low platlets a side effect?

Being treated for UTI, has red spots all over.
Asked by: Kathy J
Definitely discuss this reaction with your veterinarian. Its hard to say if its a rash related to the drug, or other side effect, or possibly non related. Make sure to mention to your veterinarian if they ever prescribe it again. Another antibiotic may be a good idea just to be on the safe side if it was a reaction to this particular drug.
Answered by: Kelly P
Date published: 2015-04-09

How old or what weight is ok for a kitten?

I recently rescued 2 kittens who had a sister get diagnosed with coccidiosis. Her vet had her contact anyone who had part of the litter or the mother. I myself did not get to ask her what dosage for such a small kitten...
Asked by: rach
Even manipulated, it's very likely that these double-strength tablets would be too high of a dosage for those kittens. There is a liquid version available at a local community pharmacy (for humans) that is available in a lower dosage. Please consult with your veterinarian as to which treatment and dosage form of the medication is best for the kittens.
Answered by: Lilli Pharmacist
Date published: 2014-08-08

IS DRUG GOOD FOR COCCIDIA TREATMENT IN CATS & DOGS?

THE DRUG SULFAMETHOXAZOLE + TRIMETHOPRIM 480 MG.
Asked by: BMC
Yes. Some vets may prefer to prescribe ALBON. We carry that in both a liquid and tablet form.
Answered by: Linda M 1800petmeds pharmacist
Date published: 2014-03-06

Is the dose 13mg per pound of Bactrim 800mg/160mg tablets divided out from 960 or just the 800?

Asked by: anonymous
The dose is based on the total amount of drug, that is the 960mg.
Answered by: Pharmacist
Date published: 2014-03-01

can you give to a guinea pig?

Asked by: waatt
Waatt, Thank-you for your question! You cannot give the double Sulfamethoxazole and Trimethoprim tablets Double Strength to a guinea pig. The dosing in the tablets are much too strong for such a small animal. Veterinarians typically prescribe an oral suspension that is not as strong as the tablets if a guinea pig requires the antibiotic, which can be appropriately dosed based on their weight. Jessica A. Pharmacy Intern 1800PetMeds
Answered by: Dulcineas17
Date published: 2013-03-13

Is this medication need RX?

Asked by: Shely
Yes, this medication does require a prescription.
Answered by: Kelly P
Date published: 2012-09-29
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