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Simplicef


 
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  Product Info   How to use   Ingredients   Customer Reviews   Q & A  

What is Simplicef?

Simplicef is a once-a-day cephalosporin antibiotic used to treat skin infections (wounds and abscesses) caused by susceptible strains of bacteria. Simplicef requires a prescription from your veterinarian, and is sold per tablet.
For: Dogs

Benefits:
FDA-approved for treating canine bacterial skin infections
Simple once-a-day dosing
Can be given with or without food
Comes in a film-coated tablet for easy administration

How it works:
Simplicef is effective against most gram-positive and gram-negative bacteria. Cephalosporin antibiotics suppress the growth of micro-organisms such as bacteria, fungi, or protozoa.

Cautions:
Contact your veterinarian in the event of an allergic reaction (such as shortness of breath, hives, swelling, rash, fainting, vomiting, diarrhea, muous or blood in the stool, unusual bleeding, or bruising). Do not give Simplicef at the same time as antacids such as Maalox or other stomach acid-reducers, like Tagamet.


More Information:
 
Brand Name
Simplicef (Pfizer Animal Health), Vantin (Pharmacia and Upjohn)
Generic Name
Cefpodoxime proxetil

What is the most important information I should know about Simplicef: Simplicef is a prescription medication FDA-approved for use in dogs. Simplicef is available as 100mg elliptical scored tablets and 200mg tablets that can either be elliptical, unscored tablets marked 5229 or capsule-shaped, scored tablets marked 5229. The usual dose of Simplicef in dogs is 2.3-4.5mg/pound, given by mouth, once a day for 5 to 7 days or 2 to 3 days beyond the cessation of clinical signs, up to a maximum of 28 days. Simplicef should be given with food to increase absorption by the body. Give all of the Simplicef that is prescribed for your pet. Symptoms may begin to improve before the infection is completely treated.

What is Simplicef: Simplicef is an antibiotic belonging to a class of drugs called cephalosporins that fight bacteria in the body. Simplicef can be used to treat many different types of infections such as bronchitis or pneumonia as well as ear, skin, and urinary tract infections. Simplicef may also be used for purposes other than those listed.

What should I discuss with my veterinarian before giving Simplicef to my pet: Tell your veterinarian if your pet has ever had an allergic reaction to another penicillin or to a cephalosporin. Tell your veterinarian if your pet has kidney disease or stomach or intestinal disease. Tell your veterinarian if your pet is pregnant or lactating.

How should this medication be given: Give this medication exactly as directed by your veterinarian. Simplicef should be given with food to increase absorption in the body. Keep plenty of water available for your pet to drink. Do not give Simplicef at the same time as giving antacids such as Maalox or other stomach acid reducers such as Tagamet as this may decrease the absorption of Simplicef. Give all of the Simplicef even if your pet appears to be better. Symptoms may improve before the infection is completely treated. Store tablets at room temperature away from moisture or heat. 

What happens if I miss giving a dose: Give the missed dose as soon as you remember. Do not give a double dose unless otherwise directed by your veterinarian.

What happens if I overdose the pet: Seek emergency veterinary medical treatment if an overdose is suspected. Symptoms of overdose may include nausea, vomiting, diarrhea, and abdominal cramps.

What should I avoid while giving Simplicef to my pet: Do not give Simplicef at the same time as giving antacids such as Maalox or other stomach acid reducers such as Tagamet.

What are the possible side effects of Simplicef: Stop giving Simplicef and seek emergency veterinary medical care in the event of an allergic reaction (shortness of breath; hives; swelling of the lips, tongue, or face; rash; or fainting), severe nausea, vomiting or diarrhea, mucus or blood in the stool, and unusual bleeding or bruising. Other, less serious side effects such as mild nausea, diarrhea, or yeast infection may be more likely to occur.  Continue to give Simplicef and notify your veterinarian if these symptoms occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What other drugs will affect Simplicef: Before giving Simplicef, tell your veterinarian if your pet is being given another antibiotic (for the same or a different infection), probenecid, a loop diuretic such as furosemide, or warfarin. You may need to have the dosage adjusted. Drugs other than those listed here may also interact with Simplicef. Talk to your veterinarian or pharmacist before giving any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information: Your pharmacist has additional information about Simplicef written for health professionals that you may read.

 

Directions:
Simplicef is an antibiotic belonging to a class of drugs called cephalosporins that fight bacteria in the body.
Simplicef can be used to treat many different types of infections such as bronchitis and pneumonia as well as ear, skin, and urinary tract infections.
Tip: Simplicef should be given with food to increase absorption by the body.
Dosage:
Pet Weight Dosage
Dogs: All weights Give this medication exactly as directed by your veterinarian. The usual dose of Simplicef in dogs is 2.3-4.5mg/pound, given by mouth, once a day for 5 to 7 days or 2 to 3 days beyond the cessation of clinical signs, up to a maximum of 28 days.
Cats
Horses:
Storage: Should be stored in a cool dry place.
Simplicef 100 mg:
Ingredient Strength
Cefpodoxime proxetil 100 mg

Simplicef 200 mg:
Ingredient Strength
Cefpodoxime proxetil 200 mg

Simplicef 4.6 5 27 27
great product we had done everything for our dog and her severe allergies, nothing worked. she was unhappy.she has been on simplicef 100 mg 1/1/2 tablet with food a dy for over 3 years on this drug. her allergies, fallen hair, red bumps, scratching etc stop a few days after she started drug. she is almost 13 healthy, coat is shinny and full, no red bumps, no scratching, nothing. she is happy. this is a miracle drug and very expensive. she is worth it. 05/16/2011
Simplicef Product Review One of the most frustrating problems I have faced as a veterinarian of 18 plus years experience is in client compliance in treating various infections at the appropriate dosing frequency and length of time. Many commonly used veterinary antibiotics either are very large to administer, often being in large capsule form, or have very poor palatability thereby frustrating animal guardians who will then be more likely not to follow the prescribed course of antibiotics, if there is too much of a struggle in administering a prescribed medication.. When Pfizer came out with this wonderful, easy to administer ONCE daily antibiotic, the compliance rate and clinical success rate in treated dogs improved dramatically for my clients. From its coated formulation and small size, this antibiotic is much easier to administer and use by my clients. Unlike other cephalosporins, like cephalexin, that often have to be given twice or three times daily, this small caplet reaches therapeutic concentrations in the blood for prolonged periods with only once daily administration. In particular this is most useful when treating the common staph skin infections in dogs , where length of therapy is sometimes 4-6 weeks or longer. With the development and efficacy of simplicef, I have seen much better case outcomes, especially with these skin cases, as well as other soft tissue infections including those of the urinary tract and lungs. I find that giving it with a small amount of food cuts down on any small chance at digestive upset. Of course like other antibiotics administered orally to our animals, a written prescription is necessary from your veterinarian. It is slightly more expensive, however in my opinion, the extra cost is certainly worth it, given the improved compliance and clinical outcome of my cases. I therefore give this product an overall rating and efficacy of a 5 with a taste and ease of use a 5 as well. 05/04/2009
This works great, all sores gone. We had our little guy on the two week, or 20 day plan whenever the sores started. We read about someone giving their dog the Simplicef only on weekends and this kept it clean. We started Zorro on this plan and it has been 100% effective for him. When he was on the one a day 1/2 pill regiment he seemed to gain weight. Now he has lost a few pounds and is back to his "bossy" self with lots of energy. 02/03/2014
Very good product My Ali suffers from bacteria around his chin and lips because he is a Boxer and they tend to slobber. His bumps are more like acne and when ruptured by scratching they bleed and become more irritating. Simplicef, after three days he is cured. Of course if I want to avoid future breakouts I give him a pill a day. This gives me peace of mind and a happy pet. 01/20/2014
Excellent! My dog gets really dry skin, and when I say really, I mean REALLY BAD. It was getting to the point where I was giving him baths every day just so he would stop itchy. After a nice week wait to get an appointment, when the vet finally saw me, she gave my sheltie these pills. That was over a year ago. Now, when the whether is bad, which sets off the dryness/raw spots on my dog, I call in, and they give me a refill. It is the ONLY thing that I have found to work for my dog's dry skin. 08/02/2013
48 Questions · 60 Answers

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she is 70 # and has taken a 200mg tablet for a bacterial infection. she is also taking 350mg aspirin for fever. puppies are 4 weeks old and eating puppy chow as well as nursing
3 months, 3 weeks ago
by
lorraine
new castle, pa
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Answer: 
Your veterinarian is aware that your dog is lactating ? At times veterinarians have to decide
benefits versus risks. As long as your vet is monitoring the situation , chances are that all will be ok.
There is some risk with any medication, however the infection in the mother dog has to be
addressed quickly. If anything seems not right to you....trouble breathing, oversedation...then call your vet immediately
.
3 months, 3 weeks ago
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Linda M 1800petmeds pharmacist
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Her third eye is drifting out to cover her left eye. This has never happened before.
6 months ago
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Anonymous
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Answer: 
Meant to type third eyelid.
6 months ago
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Ella
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11 months ago
by
Anonymous
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Answer: 
Please contact your veterinarian as soon as possible.
11 months ago
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Stephanie Duesler, Pharm. D, MBA
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1 year, 10 months ago
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Kim
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Answer: 
If a human took this by accident, they should call their physician for advice and tell them that they took cefpodoxime, which is the generic name that a medical doctor would recognize.
1 year, 10 months ago
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Kelly P
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Recently picked up a dog from the shelter to get her shots and get her spayed. My new foster was given Simplicef for a skin infection the vet noticed. Directions are 1tablet per day (looks to be about 2 weeks worth of pills). Also we are almost positive she has a UTI (found out after the vet trip). I will call the vet on Monday but would like a second opinion in the meantime.
1 year, 11 months ago
by
Anonymous
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Answer: 
Hello,

Yes, Simplicef (cefpodoxime proxetil) is indicated for UTI treatment (involving the bacterial species E. coli, K. pneumoniae, P. mirdbilis, or S. saprophyticus); symptoms typically resolve 7-10 days after the first dose. Definitely be sure to consult your veterinarian, becaue the dosing schedule for a skin infection may vary from that of a UTI. Thank you.
1 year, 11 months ago
by
Rich - Student Pharmacist
Pompano
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This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies.
 
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