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Simplicef

Starts $2.64 $2.11 per tablet
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100mg Tablet #10738
$2.64
$2.11
200mg Tablet #10739
$5.49
$4.39
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Starts $2.64 $2.11 per tablet
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Simplicef?

Simplicef is a once-a-day cephalosporin antibiotic used to treat skin infections (wounds and abscesses) caused by susceptible strains of bacteria. Simplicef requires a prescription from your veterinarian, and is sold per tablet.

For:

Dogs

Benefits:
  • FDA-approved for treating canine bacterial skin infections
  • Simple once-a-day dosing
  • Can be given with or without food
  • Comes in a film-coated tablet for easy administration
How it Works:

Simplicef is effective against most gram-positive and gram-negative bacteria. Cephalosporin antibiotics suppress the growth of micro-organisms such as bacteria, fungi, or protozoa.

Cautions:

Contact your veterinarian in the event of an allergic reaction (such as shortness of breath, hives, swelling, rash, fainting, vomiting, diarrhea, mucus or blood in the stool, unusual bleeding, or bruising). Do not give Simplicef at the same time as antacids such as Maalox or other stomach acid-reducers, like Tagamet.

Brand Name:

Simplicef (Pfizer Animal Health), Vantin (Pharmacia and Upjohn)

Generic Name:

Cefpodoxime proxetil

What is the most important information I should know about Simplicef:

Simplicef is a prescription medication FDA-approved for use in dogs. Simplicef is available as 100mg elliptical scored tablets and 200mg tablets that can either be elliptical, unscored tablets marked 5229 or capsule-shaped, scored tablets marked 5229. The usual dose of Simplicef in dogs is 2.3-4.5mg/pound, given by mouth, once a day for 5 to 7 days or 2 to 3 days beyond the cessation of clinical signs, up to a maximum of 28 days. Simplicef should be given with food to increase absorption by the body. Give all of the Simplicef that is prescribed for your pet. Symptoms may begin to improve before the infection is completely treated.

What is Simplicef:

Simplicef is an antibiotic belonging to a class of drugs called cephalosporins that fight bacteria in the body. Simplicef can be used to treat many different types of infections such as bronchitis or pneumonia as well as ear, skin, and urinary tract infections. Simplicef may also be used for purposes other than those listed.

What should I discuss with my veterinarian before giving Simplicef to my pet:

Tell your veterinarian if your pet has ever had an allergic reaction to another penicillin or to a cephalosporin. Tell your veterinarian if your pet has kidney disease or stomach or intestinal disease. Tell your veterinarian if your pet is pregnant or lactating.

How should this medication be given:

Give this medication exactly as directed by your veterinarian. Simplicef should be given with food to increase absorption in the body. Keep plenty of water available for your pet to drink. Do not give Simplicef at the same time as giving antacids such as Maalox or other stomach acid reducers such as Tagamet as this may decrease the absorption of Simplicef. Give all of the Simplicef even if your pet appears to be better. Symptoms may improve before the infection is completely treated. Store tablets at room temperature away from moisture or heat. 

What happens if I miss giving a dose:

Give the missed dose as soon as you remember. Do not give a double dose unless otherwise directed by your veterinarian.

What happens if I overdose the pet:

Seek emergency veterinary medical treatment if an overdose is suspected. Symptoms of overdose may include nausea, vomiting, diarrhea, and abdominal cramps.

What should I avoid while giving Simplicef to my pet:

Do not give Simplicef at the same time as giving antacids such as Maalox or other stomach acid reducers such as Tagamet.

What are the possible side effects of Simplicef:

Stop giving Simplicef and seek emergency veterinary medical care in the event of an allergic reaction (shortness of breath; hives; swelling of the lips, tongue, or face; rash; or fainting), severe nausea, vomiting or diarrhea, mucus or blood in the stool, and unusual bleeding or bruising. Other, less serious side effects such as mild nausea, diarrhea, or yeast infection may be more likely to occur.  Continue to give Simplicef and notify your veterinarian if these symptoms occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What other drugs will affect Simplicef:

Before giving Simplicef, tell your veterinarian if your pet is being given another antibiotic (for the same or a different infection), probenecid, a loop diuretic such as furosemide, or warfarin. You may need to have the dosage adjusted. Drugs other than those listed here may also interact with Simplicef. Talk to your veterinarian or pharmacist before giving any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information:

Your pharmacist has additional information about Simplicef written for health professionals that you may read.

How to Use
Directions:
  • Simplicef is an antibiotic belonging to a class of drugs called cephalosporins that fight bacteria in the body.
  • Simplicef can be used to treat many different types of infections such as bronchitis and pneumonia as well as ear, skin, and urinary tract infections.
Tip:

Simplicef should be given with food to increase absorption by the body.

Dosage:
Dogs:
Weight
Dosage
All weights
Give this medication exactly as directed by your veterinarian. The usual dose of Simplicef in dogs is 2.3-4.5mg/pound, given by mouth, once a day for 5 to 7 days or 2 to 3 days beyond the cessation of clinical signs, up to a maximum of 28 days.
Cats
Do not use!
Horses:
Do not use!
Storage:

Should be stored in a cool dry place.

Ingredients
Simplicef 100 mg:
Ingredient
Strength
Cefpodoxime proxetil
100 mg
Simplicef 200 mg:
Ingredient
Strength
Cefpodoxime proxetil
200 mg
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