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Monthly heartworm and flea prevention in the convenience of a tablet.
 
  • Prevents heartworm disease
  • Controls flea population
  • Controls hookworms
  • Removes and controls roundworms
  • Removes and controls whipworms
  • Beef flavor tablet
  • For dogs only
  •  
     
     

    Sentinel

     
    Q & A
    Starts at $38.69 Ships in one business day or less
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      Dogs:




       
     
     
      Product Info   How to use   Ingredients   Customer Reviews   Q & A  

    What is Sentinel?

     

    Sentinel is the only monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. Sentinel requires a prescription from your veterinarian.

    For:
    Dogs
     
    Benefits:
    Comes in palatable flavored tabs
    Easy to administer just once a month

    How it works:
    Milbemycin oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm, roundworm, and whipworm infestations. Lufenuron, the other active ingredient, is an insect development inhibitor that breaks the flea life cycle by inhibiting egg development. Lufenuron prevents most flea eggs from hatching or maturing into adults and thus prevents and controls flea populations by breaking the life cycle.

    Sentinel may be given along with Capstar, which treats flea infestation.

    Cautions:
    Side effects are rare, though some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, or seizures. If these or other symptoms develop contact your veterinarian. Its important to maintain good personal hygiene, since humans can contract hookworms and roundworms. Its also important to eliminate fleas and to not feed your pet uncooked meat or fish. To prevent re-infection, clean up stools on a daily basis. Consult your veterinarian for pregnant or lactating dogs.


    More Information:
    Brand Name
    Sentinel (Novartis)
    Generic Name
    Milbemycin Oxime (mil¿-beh-my¿-sin ox¿-eem) and Lufenuron (lew-fen¿-your-on)

    What is the most important information I should know about Sentinel: Sentinel is a prescription medication FDA-approved for use in dogs. Sentinel is available as artificial beef flavored (derived from pork and soy protein) chewable tablets. This medication should be given once a month year-round.

    What is Sentinel: Sentinel is given once a month for the prevention of heartworm disease in dogs. Sentinel also protects against hookworms, roundworms, and whipworms. Sentinel is also used to control fleas by preventing the development of flea eggs. Sentinel does not kill adult fleas. The American Heartworm Society recommends that heartworm prevention be used year-round. Sentinel may also be used for purposes other than those listed in this guide.

    What should I discuss with my veterinarian before giving Sentinel to my pet: Tell your veterinarian if your pet has ever had an allergic reaction to the medication.

    How should this medication be given: Give Sentinel exactly as directed by the veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. The usual dose of Sentinel for dogs 2 to 10 pounds is 2.3mg/46mg, 11 to 25 pounds is 5.75mg/115mg, 26 to 50 pounds is 11.5mg/230mg and 51 to 100 pounds is 23mg/460mg given once a month year-round. For dogs over 100 pounds give the appropriate combination of tablets. Heartworm testing should be performed prior to the start of prevention therapy. If your pet is off Sentinel for 6 months or less, re-start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Sentinel at room temperature. Do not remove the tablet from its wrapper until ready to give the medicine. Keep this medication away from children and pets. Consult your veterinarian for pregnant or lactating dogs.  

    What happens if I miss giving a dose: Give the missed dose as soon as you remember. Do not give a double dose of the medication.

    What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include depression, drowsiness, vomiting, loss of appetite, diarrhea, hypersalivation, seizures, and weakness.

    What should I avoid while giving Sentinel to my pet: Because humans can contract hookworms and roundworms from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household and to not feed your pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.

    What are the possible side effects of Sentinel: Side effects of Sentinel are rare although some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, hypersalivation, seizures, and weakness. If these or other symptoms develop contact your veterinarian.

    What other drugs will affect Sentinel: While Sentinel is safe to use in dogs at risk for MDRI-allele mutation (Australian Shepherds, Collies, Shelties,etc.), unless tested normal, caution is advised if the pet is also being given amiodarone (Cordarone), azole antifungals such as ketoconazole, carvedilol (Coreg), cyclosporine (Atopica), diltiazem (Cardizem), erthromycin (Ery-Tabs) or clarithromycin (Biaxin), quinidine, spironolactone (Adlactone), tamoxifen, and verapamil (Calan). Do not give Sentinel to your pet if already giving an alternate heartworm medication.

    Where can I get more information: Your pharmacist has additional information about Sentinel written for health professionals that you may read.

     

    Directions:
    Give Sentinel Flavor Tabs once a month on the same day of each month year-round.
    Sentinel Flavor Tabs is for use in dogs only. Do not give to cats.
    Watch your dog closely following dosing to be sure the entire dose has been swallowed. If it is not completely swallowed, give one more full recommended dose as soon as possible.
    Tip: Do not remove Sentinel from its wrapper until ready to give to your pet.
    Dosage:
    Pet Weight Dosage
    Dogs/puppies: (4 weeks of age or older)
    2-10 lbs Give 1 Flavor Tab every month
    (Brown Box)

    11-25 lbs Give 1 Flavor Tab every month
    (Green Box)

    26-50 lbs Give 1 Flavor Tab every month
    (Yellow Box)
      51-100 lbs Give 1 Flavor Tab every month
    (White Box)

    Over 100 lbs Give combination of Flavor Tabs based on weight
    Cats:
    Horses:
    Storage: Should be stored at room temperature between 59° and 77° F.
    Sentinel Brown for Dogs 2-10 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 2.3 mg
    Lufenuron 46 mg

    Sentinel Green for Dogs 11-25 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 5.75 mg
    Lufenuron 115 mg

    Sentinel Yellow for Dogs 26-50 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 11.5 mg
    Lufenuron 230 mg

    Sentinel White for Dogs 51-100 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 23 mg
    Lufenuron 460 mg

    Sentinel 4.4 5 595 602
    Excellent product Have used this product for several years on my three dogs. It keeps the flea and ticks controlled in our household. Through using this product, we have stopped spraying for indoor fleas, and/or hiring to have a professional spray for fleas. Our dogs are comfortable all year long. We also are assured of the heartworm protection, as our vet test's show As far as heartworm and flea protection, I highly recommend Sentinel. 04/08/2015
    Awesome Product I have used Sentinel since I got my 45 lbs mix. It has worked great and while my dog won't eat it out right if I put it in a little bit of peanut butter he doesn't even notice. I would like to point out that Sentinel does not kill adult fleas and should not be your only source of flea protection. It keeps flea eggs from developing so if you are not using a topical treatment as well your dog will likely get fleas they just won't be able to reproduce. my dog has a very sensitive stomach and has never had a bad reaction to this product. 04/06/2015
    excellent product I use Sentinel for both of my Shelties. In Florida, we have to use heartworm protection year round. My Shelties have never had fleas or heartworm problems. 04/04/2015
    Mini Aussie approved Despite reassurance from the veterinarian, I was just too paranoid giving my 12 week-old Mini Australian Shepherd the Tri-Heart she prescribed as his heartworm preventative. Thankfully she was understanding of my hesitance with ivermectin (as I'm unsure of the presence of an MDR1 mutation) and approved him for Sentinel instead. My pup didn't exactly gobble it down, but he did eat the flavor tab with little fuss, and I'm happy to report, NO SIDE EFFECTS! Very thankful. I'm unable to gauge it's effectiveness at this time, but so far, so good. 04/04/2015
    My dog hated to eat it I usually buy heart guard and my dog would chew them up like candy. I recently bought Sentinel because i needed something to prevent fleas. HATE the liquid that goes on the back. It stains my couch. I gave the pill to my dog and i found it broken up on the floor. I then mixed it up with her food. I found the broken pieces picked out of her food. She is so sneaky! Ill have to try something else next time. Crush it up i guess. 04/02/2015
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    351 Questions · 654 Answers

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    1 answer

    Sentinel

    I was told today by a Vet assistant that the product Sentinel is very hard to get, that at one time last year they stopped making it. I am know taking care of my Daughters Yorkie Poo, and that is what she has had him on since he was able to start taking it, Know that I am taking care of him, I went and tried to get him a prescription for the Sentinel, and they told me it was to hard to get, and was trying to push what they sell at me, I just wanted to find out if that is true about the product is hard to get, and the company is fixing to dissolve. Randy
    2 days ago
    by
    Anonymous
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    Answer: 
    Sentinel was unavailable for a period of time; however, we currently have it in stock.
    1 day ago
    by
    Cheryl-Pharmacist
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    Soyenka was taking Sentinal. After skin problem, Vet prescribed Comfortis. Vet also mentioned Trifexis. Can she finish the Sentinal before anything else, or can she take the Sentinal and the Comfortis. together?
    2 weeks, 3 days ago
    by
    Poppy
    Miami
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    Answer: 
    You would usually wait a month between any heartworm preventions, so if you finish the sentinel, you would wait a month before starting Trifexis. Sentinel and comfortis can be used together if the veterinarian has prescribed them both and has recommended that you use both. Trifexis and comfortis would not be used together, they have one active ingredient that is the same and therefore would not be used together.
    2 days ago
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    Kelly P
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    3 weeks, 2 days ago
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    Toby
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    Answer: 
    The difference between Sentinel and Sentinel Spectrum is that Sentinel Spectrum also deworms for tapeworms while Sentinel does not. Both prevent heartworms, controls fleas and treats for hookworms, roundworms and whipworms.
    3 weeks ago
    by
    SuzyCVT
    Florida
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    1 month, 4 weeks ago
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    Anonymous
    Hawaii
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    Answer: 
    Sentinel is safe to use on pups 8 weeks of age and older. However, if your pup has not been on any heartworm prevention, it will need a heartworm test before being put on any as it could already be infected.
    3 weeks ago
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    SuzyCVT
    Florida
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    1 answer

    Overdose ???

    We are away for 3 months this winter. I brought 3 months supply of Sentinel with us for our mixed breed 37 lb 3 year old dog. She gets car sick so I also brought Bonine per our vets recommendations.. A few days ago before taking her in the car I accidentally gave her Sentinel instead of Bonide. She threw up in the car but I just thought the Bonide wasn't working. Then I realized my mistake. I only have one Sentinel pill left and I should have two for dosing on Feb 15 and March 15. What should I do? .
    2 months ago
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    Anonymous
    Fkirida
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    Answer: 
    Don't be concerned about your dog getting 2 doses of Sentinel as it is very safe. Just purchase another dose for the missing treatment.
    3 weeks ago
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    SuzyCVT
    Florida
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    • 2015-04-12T07:29:32.667-05:00
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    This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
    Note: Any trademarks are the property of their respective companies.
     
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