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Monthly heartworm and flea prevention in the convenience of a tablet.
 
  • Prevents heartworm disease
  • Controls flea population
  • Controls hookworms
  • Removes and controls roundworms
  • Removes and controls whipworms
  • Beef flavor tablet
  • For dogs only
  •  
     
     

    Sentinel

     
    Q & A
    Starts at $42.99 Ships in one business day or less
    1_Select a Weight
      Dogs:




       
     
     
      Product Info   How to use   Ingredients   Customer Reviews   Q & A  

    What is Sentinel?

     

    Sentinel is the only monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. Sentinel requires a prescription from your veterinarian.

    For:
    Dogs
     
    Benefits:
    Comes in palatable flavored tabs
    Easy to administer just once a month

    How it works:
    Milbemycin oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm, roundworm, and whipworm infestations. Lufenuron, the other active ingredient, is an insect development inhibitor that breaks the flea life cycle by inhibiting egg development. Lufenuron prevents most flea eggs from hatching or maturing into adults and thus prevents and controls flea populations by breaking the life cycle.

    Sentinel may be given along with Capstar, which treats flea infestation.

    Cautions:
    Side effects are rare, though some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, or seizures. If these or other symptoms develop contact your veterinarian. Its important to maintain good personal hygiene, since humans can contract hookworms and roundworms. Its also important to eliminate fleas and to not feed your pet uncooked meat or fish. To prevent re-infection, clean up stools on a daily basis. Consult your veterinarian for pregnant or lactating dogs.


    More Information:
    Brand Name
    Sentinel (Novartis)
    Generic Name
    Milbemycin Oxime (milí-beh-myí-sin oxí-eem) and Lufenuron (lew-fení-your-on)

    What is the most important information I should know about Sentinel: Sentinel is a prescription medication FDA-approved for use in dogs. Sentinel is available as artificial beef flavored (derived from pork and soy protein) chewable tablets. This medication should be given once a month year-round.

    What is Sentinel: Sentinel is given once a month for the prevention of heartworm disease in dogs. Sentinel also protects against hookworms, roundworms, and whipworms. Sentinel is also used to control fleas by preventing the development of flea eggs. Sentinel does not kill adult fleas. The American Heartworm Society recommends that heartworm prevention be used year-round. Sentinel may also be used for purposes other than those listed in this guide.

    What should I discuss with my veterinarian before giving Sentinel to my pet: Tell your veterinarian if your pet has ever had an allergic reaction to the medication.

    How should this medication be given: Give Sentinel exactly as directed by the veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. The usual dose of Sentinel for dogs 2 to 10 pounds is 2.3mg/46mg, 11 to 25 pounds is 5.75mg/115mg, 26 to 50 pounds is 11.5mg/230mg and 51 to 100 pounds is 23mg/460mg given once a month year-round. For dogs over 100 pounds give the appropriate combination of tablets. Heartworm testing should be performed prior to the start of prevention therapy. If your pet is off Sentinel for 6 months or less, re-start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Sentinel at room temperature. Do not remove the tablet from its wrapper until ready to give the medicine. Keep this medication away from children and pets. Consult your veterinarian for pregnant or lactating dogs.  

    What happens if I miss giving a dose: Give the missed dose as soon as you remember. Do not give a double dose of the medication.

    What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include depression, drowsiness, vomiting, loss of appetite, diarrhea, hypersalivation, seizures, and weakness.

    What should I avoid while giving Sentinel to my pet: Because humans can contract hookworms and roundworms from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household and to not feed your pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.

    What are the possible side effects of Sentinel: Side effects of Sentinel are rare although some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, hypersalivation, seizures, and weakness. If these or other symptoms develop contact your veterinarian.

    What other drugs will affect Sentinel: While Sentinel is safe to use in dogs at risk for MDRI-allele mutation (Australian Shepherds, Collies, Shelties,etc.), unless tested normal, caution is advised if the pet is also being given amiodarone (Cordarone), azole antifungals such as ketoconazole, carvedilol (Coreg), cyclosporine (Atopica), diltiazem (Cardizem), erthromycin (Ery-Tabs) or clarithromycin (Biaxin), quinidine, spironolactone (Adlactone), tamoxifen, and verapamil (Calan). Do not give Sentinel to your pet if already giving an alternate heartworm medication.

    Where can I get more information: Your pharmacist has additional information about Sentinel written for health professionals that you may read.

     

    Directions:
    Give Sentinel Flavor Tabs once a month on the same day of each month year-round.
    Sentinel Flavor Tabs is for use in dogs only. Do not give to cats.
    Watch your dog closely following dosing to be sure the entire dose has been swallowed. If it is not completely swallowed, give one more full recommended dose as soon as possible.
    Tip: Do not remove Sentinel from its wrapper until ready to give to your pet.
    Dosage:
    Pet Weight Dosage
    Dogs/puppies: (4 weeks of age or older)
    2-10 lbs Give 1 Flavor Tab every month
    (Brown Box)

    11-25 lbs Give 1 Flavor Tab every month
    (Green Box)

    26-50 lbs Give 1 Flavor Tab every month
    (Yellow Box)
      51-100 lbs Give 1 Flavor Tab every month
    (White Box)

    Over 100 lbs Give combination of Flavor Tabs based on weight
    Cats:
    Horses:
    Storage: Should be stored at room temperature between 59° and 77° F.
    Sentinel Brown for Dogs 2-10 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 2.3 mg
    Lufenuron 46 mg

    Sentinel Green for Dogs 11-25 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 5.75 mg
    Lufenuron 115 mg

    Sentinel Yellow for Dogs 26-50 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 11.5 mg
    Lufenuron 230 mg

    Sentinel White for Dogs 51-100 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 23 mg
    Lufenuron 460 mg

    Sentinel 4.5 5 550 557
    save your money this does not work I used to give my dogs Progam pills but they no longer make them so being a good mom I looked for another pill form flea treatment. I took my dogs to the vet so I could get a Rx to get them on Sentinal. This Summer my poor dogs have red bumps and they are always scratching. My husband said that he thinks that have fleas and of course I said that was impossible because they were on Sentinal pills. To my horror I found out that Sentinal DOES NOT WORK! 08/25/2014
    I bought this for my 7 Lbs pomeranian.It did not do anything.I actually felt like it acted more like a magnet than anything else.I bought a 6-pack and donot even know what to do with the rest. 08/25/2014
    Doesn't prevent fleas Totally useless in South Florida or anywhere where your dog can pick up a flea outside, because it doesn't kill them (only prevents their eggs from hatching). Was forced by the "clinic" to switch from Revolution to this garbage, it is totally useless. Took an entire week before my dog got fleas and is totally miserable. 08/20/2014
    SENTINEL IS NOT A FLEA/TICK TREATMENT!!! Seems to be a LOT of confusion over what meds for what issues. A summary from information collected from my vet: FLEA/TICK meds: CapStar-kills fleas for 24 hrs. Generally used as a quick kill for bad infestations, sold in single doses Comfortis-only kills adult fleas, NOT ticks Frontline Plus-kills fleas, ticks & has IGR (insect growth regulator). NexGard-kills fleas, ticks-most expensive I've seen probably because it's new(er) K9 Advantix II-kills fleas, ticks & has IGR. Repels mosquitoes, lice, biting flies, gnats, fleas. Drs. Foster & Smith claim to use on their dogs. Cheaper than Frontline Plus on their website & Frontline seems to have lost it's effectiveness on my dogs so I'm trying this since it sounds better for less money. These are the main, possibly ONLY once monthly meds that kill BOTH fleas/ticks. HEARTWORM meds: Heartgard-kills heart/round/hookworms. Doesn't kill whips so if your dog fancies eating feces, try Sentinel-kills heart/round/hook/whip worms & FLEA EGGS ONLY, not adults & not ticks! Trifexis-kills heart/round/hook/whip worms & adult fleas Interceptor-DISCONTINUED, replaced with Sentinel Hope this helps! I spent days researching, read lots of scary reviews for virtually all these products! CHECK WITH YOUR VET BEFORE USING ANYTHING AS SOME MEDS HAVE BREED SPECIFIC INTERACTIONS!!! My personal experience has been great with Sentinel, used for YEARS on my Heeler & Pom. Will post update after using K9 Advantix II. I used Frontline Plus for years also but as I said, not so good anymore. Had to Capstar my Pom last year even though I was using Frontline. 08/19/2014
    tastes awful We used to use heart guard and my dog was always excited for a tasty 'treat' but he refuses to eat sentinel and even in cheese, cream cheese, apple, ground into his dinner (not in pb, he can't eat that)… he can still smell/taste it enough that he refuses to eat any of those treats with it. No wonder it is on sale now nobody wants it. cannot rate effectiveness because I cannot get him to eat it 08/19/2014
    2 3 4 5 ... 20 Next
    337 Questions · 624 Answers

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    1 day ago
    by
    kathy
    sc
    Answer this question
    1 day ago
    by
    alice
    texas
    Answer this question
    Hello, hope you are doing well. Friends told me to reach out to you since you do such a great job in customer service. I have 2 labs to care for. What is the effectiveness of Sentinel (Lufenuron/Milbemycin oxime) versus Trifexis (Spinosad/Milbemycin Oxime). The ingredients are different but I don't have enough information on the second ingredient in Sentinel. Any help please. Thank you.
    1 week, 4 days ago
    by
    Anonymous
    Answer this question

    Answers

    Answer: 
    I don't know about Trifexis but save your money do not buy Sentinal! It does not work. I learned this the hard way.
    2 days ago
    by
    dog mom of 3
    California
    Vote as Best Answer
    Thanks for Voting

    Answer: 
    Both medications are effective to prevent Heartworms, roundworms, hookworms and whipworms. Their difference is the Spinosad ingredient in Trifexis kills adult fleas while the Lufenuron in Sentinel will only sterilize flea eggs instead of killing any adult fleas.
    1 week, 2 days ago
    by
    Lilli Pharmacist
    Pompano Beach, FL
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    Thanks for Voting
     
    2 answers

    Missed dose by a week

    Do we change the original,schedule to the new date
    1 month, 1 week ago
    by
    Anonymous
    Ontario, Canada
    Answer this question

    Answers

    Answer: 
    I try to stay on schedule. If you would like to switch to a new date it's not the end of the world but I would try to stay as close to the 30 days as possible.
    2 weeks, 1 day ago
    by
    Maemae
    Vote as Best Answer
    Thanks for Voting

    Answer: 
    schedule to the new date
    1 month, 1 week ago
    by
    Linda M 1800petmeds pharmacist
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    2 answers

    sentinel

    my poodle weighs 26 pounds. should i give her the 11-25# or the 26-50# sentinel tablet?
    1 month, 3 weeks ago
    by
    Anonymous
    Answer this question

    Answers

    Answer: 
    I would give the 26-50# just to be safe.
    1 month, 2 weeks ago
    by
    colliemom
    Concord, NC
    Vote as Best Answer
    Thanks for Voting

    Answer: 
    Thank you for your question. Please consult with your vet in regards to which weight range to purchase.
    1 month, 3 weeks ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    2 3 4 5 ... 13 Next
    2 3 4 5 ... 13 Next
    This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
    Note: Any trademarks are the property of their respective companies.
     
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