Sentinel is the only monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. Sentinel requires a prescription from your veterinarian.
Due to manufacturer production issues, we are offering alternatives to Sentinel.Alternatives to Sentinel
For: Dogs (4 weeks of age or older and weighing over 2 lbs)
Benefits:
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Comes in palatable flavored tabs
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Easy to administer just once a month
How it works:
Milbemycin oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm, roundworm, and whipworm infestations. Lufenuron, the other active ingredient, is an insect development inhibitor that breaks the flea life cycle by inhibiting egg development. Lufenuron prevents most flea eggs from hatching or maturing into adults and thus prevents and controls flea populations by breaking the life cycle.
Sentinel may be given along with Capstar, which treats flea infestation.
Cautions:
Side effects are rare, though some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, or seizures. If these or other symptoms develop contact your veterinarian. Its important to maintain good personal hygiene, since humans can contract hookworms and roundworms. Its also important to eliminate fleas and to not feed your pet uncooked meat or fish. To prevent re-infection, clean up stools on a daily basis. Consult your veterinarian for pregnant or lactating dogs.
Generic Name Milbemycin Oxime (mil’-beh-my’-sin ox’-eem) and Lufenuron (lew-fen’-your-on)
What is the most important information I should know about Sentinel: Sentinel is a prescription medication FDA-approved for use in dogs. Sentinel is available as artificial beef flavored (derived from pork and soy protein) chewable tablets. This medication should be given once a month year-round.
What is Sentinel: Sentinel is given once a month for the prevention of heartworm disease in dogs. Sentinel also protects against hookworms, roundworms, and whipworms. Sentinel is also used to control fleas by preventing the development of flea eggs. Sentinel does not kill adult fleas. The American Heartworm Society recommends that heartworm prevention be used year-round. Sentinel may also be used for purposes other than those listed in this guide.
What should I discuss with my veterinarian before giving Sentinel to my pet: Tell your veterinarian if your pet has ever had an allergic reaction to the medication.
How should this medication be given: Give Sentinel exactly as directed by the veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. The usual dose of Sentinel for dogs 2 to 10 pounds is 2.3mg/46mg, 11 to 25 pounds is 5.75mg/115mg, 26 to 50 pounds is 11.5mg/230mg and 51 to 100 pounds is 23mg/460mg given once a month year-round. For dogs over 100 pounds give the appropriate combination of tablets. Heartworm testing should be performed prior to the start of prevention therapy. If your pet is off Sentinel for 6 months or less, re-start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Sentinel at room temperature. Do not remove the tablet from its wrapper until ready to give the medicine. Keep this medication away from children and pets. Consult your veterinarian for pregnant or lactating dogs.
What happens if I miss giving a dose: Give the missed dose as soon as you remember. Do not give a double dose of the medication.
What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include depression, drowsiness, vomiting, loss of appetite, diarrhea, hypersalivation, seizures, and weakness.
What should I avoid while giving Sentinel to my pet: Because humans can contract hookworms and roundworms from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household and to not feed your pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.
What are the possible side effects of Sentinel: Side effects of Sentinel are rare although some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, hypersalivation, seizures, and weakness. If these or other symptoms develop contact your veterinarian.
What other drugs will affect Sentinel:While Sentinel is safe to use in dogs at risk for MDRI-allele mutation (Australian Shepherds, Collies, Shelties,etc.), unless tested normal, caution is advised if the pet is also being given amiodarone (Cordarone), azole antifungals such as ketoconazole, carvedilol (Coreg), cyclosporine (Atopica), diltiazem (Cardizem), erthromycin (Ery-Tabs) or clarithromycin (Biaxin), quinidine, spironolactone (Adlactone), tamoxifen, and verapamil (Calan). Do not give Sentinel to your pet if already giving an alternate heartworm medication.
Where can I get more information: Your pharmacist has additional information about Sentinel written for health professionals that you may read.
Directions:
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Give Sentinel Flavor Tabs once a month on the same day of each month year-round.
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Sentinel Flavor Tabs is for use in dogs only. Do not give to cats.
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Watch your dog closely following dosing to be sure the entire dose has been swallowed. If it is not completely swallowed, give one more full recommended dose as soon as possible.
Tip: Do not remove Sentinel from its wrapper until ready to give to your pet.
Dosage:
Pet
Weight
Dosage
Dogs/puppies: (4 weeks of age or older)
2-10 lbs
Give 1 Flavor Tab every month (Brown Box)
11-25 lbs
Give 1 Flavor Tab every month (Green Box)
26-50 lbs
Give 1 Flavor Tab every month (Yellow Box)
51-100 lbs
Give 1 Flavor Tab every month (White Box)
Over 100 lbs
Give combination of Flavor Tabs based on weight
Cats:
Horses:
Storage: Should be stored at room temperature between 59° and 77° F.
Stella takes her Sentinel via a pill pocket and gulps it right down versus having to grind it up and put it in her food. She has not had any reactions to her medication and passes all her tests at the vet.
Sentinel works wonderful for my 16 month old lab. I give it to her with a piece of cheese and I know she is completely protected. No fleas for this baby girl.Also thank you pet meds for a wonderful price and fast free delivery. Lacy said thank you to for the bone you gave her in the box.Thank you .
I rescued a mini long haired dachshaund in Dec. She was given Atvantage by the shelter. I went to the vet yesterday and was given a sample of Sentinel. I gave her the dose last night. She has been lethargic, scratchy and has cried a few times. This normally very upbeat perky dog is not herself! I will go back to Advantage and get Heartguard for the heart worms. So sad to see her like this,. Hope the side effects wear off
My dog has flea dermatitis, and was miserable! We could not get rid of these fleas, and I have used shampoos, sprays, spot ons, yard spray, carpet powder, house bombs (all at the same time, even!) - everything to get rid of these fleas and NOTHING worked. Sentinel not only gave us a huge advantage in getting rid of these fleas - but it gave us our happy pooch back:) Thank you!!!
There are other heartworm preventative products that your veterinarian can prescribe, such as Revolution applied to the skin, or Heartgard Plus given by mouth.
I am not familiar with diarrhea being one of the side effects of Sentinel. However, the fact that it happens every time you give this to your pet means your pet probably has a sensitivity to Sentinel. I would suggest you discuss this with your veterinarian. It may be necessary to use a different heartworm preventative.
yes.you can order it yourself,and pet meds will call your vet.also your vet can give you a refill, then you can just call or order on line and get it.i have been using sentinel for a long time ,its great and my dogs dont have fleas. try it and you will be happy.
That's a question for your veterinarian. Most veterinarians do require an annual heartworm test. However, there are some veterinarians who require it every 2 years depending on how compliant the client is in giving the pet the medication.
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.
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