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Monthly heartworm and flea prevention in the convenience of a tablet.
 
  • Prevents heartworm disease
  • Controls flea population
  • Controls hookworms
  • Removes and controls roundworms
  • Removes and controls whipworms
  • Beef flavor tablet
  • For dogs only
  •  
     
     

    Sentinel

     
    Q & A
    Starts at $42.99 Ships in one business day or less
    1_Select a Weight
      Dogs:




       
     
     
      Product Info   How to use   Ingredients   Customer Reviews   Q & A  

    What is Sentinel?

     

    Sentinel is the only monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. Sentinel requires a prescription from your veterinarian.

    For:
    Dogs
     
    Benefits:
    Comes in palatable flavored tabs
    Easy to administer just once a month

    How it works:
    Milbemycin oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm, roundworm, and whipworm infestations. Lufenuron, the other active ingredient, is an insect development inhibitor that breaks the flea life cycle by inhibiting egg development. Lufenuron prevents most flea eggs from hatching or maturing into adults and thus prevents and controls flea populations by breaking the life cycle.

    Sentinel may be given along with Capstar, which treats flea infestation.

    Cautions:
    Side effects are rare, though some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, or seizures. If these or other symptoms develop contact your veterinarian. Its important to maintain good personal hygiene, since humans can contract hookworms and roundworms. Its also important to eliminate fleas and to not feed your pet uncooked meat or fish. To prevent re-infection, clean up stools on a daily basis. Consult your veterinarian for pregnant or lactating dogs.


    More Information:
    Brand Name
    Sentinel (Novartis)
    Generic Name
    Milbemycin Oxime (milí-beh-myí-sin oxí-eem) and Lufenuron (lew-fení-your-on)

    What is the most important information I should know about Sentinel: Sentinel is a prescription medication FDA-approved for use in dogs. Sentinel is available as artificial beef flavored (derived from pork and soy protein) chewable tablets. This medication should be given once a month year-round.

    What is Sentinel: Sentinel is given once a month for the prevention of heartworm disease in dogs. Sentinel also protects against hookworms, roundworms, and whipworms. Sentinel is also used to control fleas by preventing the development of flea eggs. Sentinel does not kill adult fleas. The American Heartworm Society recommends that heartworm prevention be used year-round. Sentinel may also be used for purposes other than those listed in this guide.

    What should I discuss with my veterinarian before giving Sentinel to my pet: Tell your veterinarian if your pet has ever had an allergic reaction to the medication.

    How should this medication be given: Give Sentinel exactly as directed by the veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. The usual dose of Sentinel for dogs 2 to 10 pounds is 2.3mg/46mg, 11 to 25 pounds is 5.75mg/115mg, 26 to 50 pounds is 11.5mg/230mg and 51 to 100 pounds is 23mg/460mg given once a month year-round. For dogs over 100 pounds give the appropriate combination of tablets. Heartworm testing should be performed prior to the start of prevention therapy. If your pet is off Sentinel for 6 months or less, re-start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Sentinel at room temperature. Do not remove the tablet from its wrapper until ready to give the medicine. Keep this medication away from children and pets. Consult your veterinarian for pregnant or lactating dogs.  

    What happens if I miss giving a dose: Give the missed dose as soon as you remember. Do not give a double dose of the medication.

    What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include depression, drowsiness, vomiting, loss of appetite, diarrhea, hypersalivation, seizures, and weakness.

    What should I avoid while giving Sentinel to my pet: Because humans can contract hookworms and roundworms from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household and to not feed your pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.

    What are the possible side effects of Sentinel: Side effects of Sentinel are rare although some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, hypersalivation, seizures, and weakness. If these or other symptoms develop contact your veterinarian.

    What other drugs will affect Sentinel: While Sentinel is safe to use in dogs at risk for MDRI-allele mutation (Australian Shepherds, Collies, Shelties,etc.), unless tested normal, caution is advised if the pet is also being given amiodarone (Cordarone), azole antifungals such as ketoconazole, carvedilol (Coreg), cyclosporine (Atopica), diltiazem (Cardizem), erthromycin (Ery-Tabs) or clarithromycin (Biaxin), quinidine, spironolactone (Adlactone), tamoxifen, and verapamil (Calan). Do not give Sentinel to your pet if already giving an alternate heartworm medication.

    Where can I get more information: Your pharmacist has additional information about Sentinel written for health professionals that you may read.

     

    Directions:
    Give Sentinel Flavor Tabs once a month on the same day of each month year-round.
    Sentinel Flavor Tabs is for use in dogs only. Do not give to cats.
    Watch your dog closely following dosing to be sure the entire dose has been swallowed. If it is not completely swallowed, give one more full recommended dose as soon as possible.
    Tip: Do not remove Sentinel from its wrapper until ready to give to your pet.
    Dosage:
    Pet Weight Dosage
    Dogs/puppies: (4 weeks of age or older)
    2-10 lbs Give 1 Flavor Tab every month
    (Brown Box)

    11-25 lbs Give 1 Flavor Tab every month
    (Green Box)

    26-50 lbs Give 1 Flavor Tab every month
    (Yellow Box)
      51-100 lbs Give 1 Flavor Tab every month
    (White Box)

    Over 100 lbs Give combination of Flavor Tabs based on weight
    Cats:
    Horses:
    Storage: Should be stored at room temperature between 59° and 77° F.
    Sentinel Brown for Dogs 2-10 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 2.3 mg
    Lufenuron 46 mg

    Sentinel Green for Dogs 11-25 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 5.75 mg
    Lufenuron 115 mg

    Sentinel Yellow for Dogs 26-50 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 11.5 mg
    Lufenuron 230 mg

    Sentinel White for Dogs 51-100 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 23 mg
    Lufenuron 460 mg

    Sentinel 4.4 5 577 584
    Works great - easy to use. We have had all our dogs on Sentinel. Right now we have two German Shepherds and on the first of the month they get what we call "your healthy pill". They think they are getting a treat and chew it right up. Never had any problems with any worms and best of all no fleas. We would highly recommend Sentinel. 12/14/2014
    This product is effective I have used this project in the past with no problems. Then my Vet changed and did not provide Sentinel anymore. During that time the product that we did use on my 65 pound shepherd made him sick. He never wanted to eat it even if I hid it in his food and he was lethargic after ingesting. With Sentinel we had none of that. He ate the tab and there were no issues. Once I found 1 800 PET MEDS sold Sentinel I went back to this product and my dog is happier. 12/13/2014
    Working well for my dog My beautiful 88lb GSD does well with this product. She has some sensitivities and allergies, but so far this has not been a problem for her on Sentinel. I take care to give the monthly dose alternating with Frontline Plus at 2 week intervals between each product so as not to overload her system. Been on it for almost a year, and so far so good. 12/12/2014
    Thumbs up for Sentinel and 1-800-petmeds We have used Sentinel for Noah for a long time with great satisfaction and now we have extended that satisfaction with 1-800-petmeds. Nothing more to say but we recommend both highly. 12/07/2014
    One Shih Tzu got diarrhea My two Shih Tzu 11- week -old pups had their first dose several weeks ago. One got diarrhea badly and I had to put him on digestive enzymes. The other didn't seem to be affected. 11/25/2014
    2 3 4 5 ... 21 Next
    342 Questions · 635 Answers

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    I keep my dog on this year round. She got her last monthly dose on 10/9/14. I would like to give it to her on 11/6/14 if it is safe to do so.
    1 month, 3 weeks ago
    by
    Anonymous
    Answer this question

    Answers

    Answer: 
    Yes, you can do that safely.
    1 month, 2 weeks ago
    by
    Linda M 1800petmeds pharmacist
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    2 months, 1 week ago
    by
    Paula
    Answer this question

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    Answer: 
    Our shepherd has gulp seizures and is taking phenobarbital to control the seizures. He has not had any problems, however, I recommend checking with your vet.
    5 days ago
    by
    Dogs Mom
    Abbottstown, PA
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    Answer: 
    Please consult with your veterinarian.
    2 months, 1 week ago
    by
    Lilli Pharmacist
    Pompano Beach, FL
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    2 months, 2 weeks ago
    by
    CollieMan
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    Answer: 
    Not that we are aware of. Sentinel may be used on the collie breed.
    2 months, 2 weeks ago
    by
    Lilli Pharmacist
    Pompano Beach, FL
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    2 months, 3 weeks ago
    by
    Gary
    Kathleen ga
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    Answer: 
    Comfortis and Sentinel are both preventatives ( think) I would do Capstar to kill the fleas and the next day either Comfortis or Sentinel to prevent new ones.
    2 months, 1 week ago
    by
    Lauren
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    Answer: 
    it is not uncommon to see Sentinel and Comfortis used together , However you may want to
    consider the product TRIFEXIS..which has the ingredients of comfortis in it but also covers
    heartworm. Ask your vet want they think. Good Luck with everything !
    2 months, 3 weeks ago
    by
    Linda M 1800petmeds pharmacist
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    3 months, 3 weeks ago
    by
    barb
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    Answers

    Answer: 
    Same thing happened to my Great Dane. She got her brother's pill (along with hers) before I could give it to him. She was fine. Just super flea free!
    2 months, 1 week ago
    by
    Lauren
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    Answer: 
    Please contact your veterinarian.
    3 months, 1 week ago
    by
    Stephanie Duesler, Pharm. D, MBA
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    2 3 4 5 ... 13 Next
    2 3 4 5 ... 13 Next
    This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
    Note: Any trademarks are the property of their respective companies.
     
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