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Sentinel

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Starts $53.74 $39.85 
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Dog
02-10 lbs
11-25 lbs
26-50 lbs
51-100 lbs
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Sentinel?

Sentinel is the only monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. Sentinel requires a prescription from your veterinarian.

For:

Dogs

Benefits:
  • Comes in palatable flavored tabs
  • Easy to administer just once a month
How it Works:

Milbemycin oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm, roundworm, and whipworm infestations. Lufenuron, the other active ingredient, is an insect development inhibitor that breaks the flea life cycle by inhibiting egg development. Lufenuron prevents most flea eggs from hatching or maturing into adults and thus prevents and controls flea populations by breaking the life cycle. Sentinel may be given along with Capstar, which treats flea infestation.

Cautions:

Side effects are rare, though some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, or seizures. If these or other symptoms develop contact your veterinarian. It's important to maintain good personal hygiene, since humans can contract hookworms and roundworms. It's also important to eliminate fleas and to not feed your pet uncooked meat or fish. To prevent re-infection, clean up stools on a daily basis. Consult your veterinarian for pregnant or lactating dogs.

Brand Name:

Sentinel (Novartis)

Generic Name:

Milbemycin Oxime (mil-beh-my-sin ox-eem) and Lufenuron (lew-fen-your-on)

What is Sentinel:

Sentinel is given once a month for the prevention of heartworm disease in dogs. Sentinel also protects against hookworms, roundworms, and whipworms. Sentinel is also used to control fleas by preventing the development of flea eggs. Sentinel does not kill adult fleas. The American Heartworm Society recommends that heartworm prevention be used year-round. Sentinel may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving Sentinel to my pet:

Tell your veterinarian if your pet has ever had an allergic reaction to the medication.

What is the most important information I should know about Sentinel:

Sentinel is a prescription medication FDA-approved for use in dogs. Sentinel is available as artificial beef flavored (derived from pork and soy protein) chewable tablets. This medication should be given once a month year-round.

How should this medication be given:

Give Sentinel exactly as directed by the veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. The usual dose of Sentinel for dogs 2 to 10 pounds is 2.3mg/46mg, 11 to 25 pounds is 5.75mg/115mg, 26 to 50 pounds is 11.5mg/230mg and 51 to 100 pounds is 23mg/460mg given once a month year-round. For dogs over 100 pounds give the appropriate combination of tablets. Heartworm testing should be performed prior to the start of prevention therapy. If your pet is off Sentinel for 6 months or less, re-start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Sentinel at room temperature. Do not remove the tablet from its wrapper until ready to give the medicine. Keep this medication away from children and pets. Consult your veterinarian for pregnant or lactating dogs.

What happens if I miss giving a dose:

Give the missed dose as soon as you remember. Do not give a double dose of the medication.

What should I avoid while giving Sentinel to my pet:

Because humans can contract hookworms and roundworms from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household and to not feed your pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.

What are the possible side effects of Sentinel:

Side effects of Sentinel are rare although some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, hypersalivation, seizures, and weakness. If these or other symptoms develop contact your veterinarian.

What other drugs will affect Sentinel:

While Sentinel is safe to use in dogs at risk for MDRI-allele mutation (Australian Shepherds, Collies, Shelties, etc.), unless tested normal, caution is advised if your pet is also being given amiodarone (Cordarone), azole antifungals such as ketoconazole, carvedilol (Coreg), cyclosporine (Atopica), diltiazem (Cardizem), erythromycin (Ery-Tabs) or clarithromycin (Biaxin), quinidine, spironolactone (Aldactone), tamoxifen, and verapamil (Calan). Do not give Sentinel to your pet if already giving an alternate heartworm medication.

How to Use
Directions:
  • Give Sentinel Flavor Tabs once a month on the same day of each month year-round.
  • Sentinel Flavor Tabs is for use in dogs only. Do not give to cats.
  • Watch your dog closely following dosing to be sure the entire dose has been swallowed. If it is not completely swallowed, give one more full recommended dose as soon as possible.
Tip:

Do not remove Sentinel from its wrapper until ready to give to your pet.

Dosage:
Dogs/puppies: (4 weeks of age or older)
Weight
Dosage
2-10 lbs
Give 1 Flavor Tab every month (Brown Box)
11-25 lbs
Give 1 Flavor Tab every month (Green Box)
26-50 lbs
Give 1 Flavor Tab every month (Yellow Box)
51-100 lbs
Give 1 Flavor Tab every month (White Box)
Over 100 lbs
Give combination of Flavor Tabs based on weight
Cats:
Do not use!
Horses:
Do not use!
Storage:

Should be stored at room temperature between 59° and 77° F.

Ingredients
Sentinel Brown for Dogs 2-10 lbs:
Active Ingredient (per tablet)
Amount
Milbemycin Oxime
2.3 mg
Lufenuron
46 mg
Sentinel Green for Dogs 11-25 lbs:
Active Ingredient (per tablet)
Amount
Milbemycin Oxime
5.75 mg
Lufenuron
115 mg
Sentinel Yellow for Dogs 26-50 lbs:
Active Ingredient (per tablet)
Amount
Milbemycin Oxime
11.5 mg
Lufenuron
230 mg
Sentinel White for Dogs 51-100 lbs:
Active Ingredient (per tablet)
Amount
Milbemycin Oxime
23 mg
Lufenuron
460 mg
Customer Reviews
Sentinel is rated 4.4347 out of 5 by 697.
Rated 5 out of 5 by from Fast shipping. Easy shopping. Friendly Buying RX on line was easy. Worked with my Vet quickly preventing me from bad weather driving. Product keep my dogs free from heart worms and many other pesky parasites. Easy to use. Palatable they think they are treats. Can't think of another product that offers better protection. Thanks Pet Meds.
Date published: 2016-12-05
Rated 5 out of 5 by from I have been using Sentinel for over a year now. Our Marley does great with it. When we got her she had heart worm and had to be treated for it, she is has been heart worm free. I strongly suggest that you have your furry one on Sentinel. 1800petmed is great in keeping you updated when renewal is needed. Sincerely The Merrills
Date published: 2016-12-03
Rated 5 out of 5 by from Sentinel and 1800 Pet Meds Bruce has always been on Sentinel, so I know no different, but my vet recommended it and Bruce hasn't had any issues since. We're happy!
Date published: 2016-12-03
Rated 5 out of 5 by from Izzy They don't carry this at our vets in Beaufort, SC. So we get it off line.
Date published: 2016-11-26
Rated 5 out of 5 by from Great product! My dog loves it! It works great and using 800-Pet-Meds makes it so affordable! I will recommend it to all my friends.
Date published: 2016-11-16
Rated 5 out of 5 by from Easy ordering and way better prices! My dogs have never had any problems with worms because they take this. Quick and reliable service! Prices are better than the vets office and fast shipping. They also stay on it when needing the vets prescription!
Date published: 2016-11-13
Rated 5 out of 5 by from Flea free I have used Sentinal on my two Schnauzers for 3 to 4 years now. It works great to prevent heartworms & keeps them & our home flea free. If you have a flea 'infestation,' you will need a different approach.
Date published: 2016-11-11
Rated 5 out of 5 by from Easy Ordering Process and Fast Shipping First time ordering for PetMeds. Mailed in my prescription, and item was packaged and shipped the day it arrived. I also received it several days earlier than expected. The kicker is I payed almost $15 dollars less than it would have cost me at the vet.
Date published: 2016-11-05
  • 2016-12-07T06:04CST
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Q&A

I see where I will save 10% with the code. I received a letter that stated on my next purchase I would get a discount od 6.18 from my last purchase Will I get both on this purchase

Asked by: shuber5410
Please contact our sales department for pricing and special discounts
Answered by: S Duesler PharmD MBA
Date published: 2016-11-17

my puppy weighs 10.5 pounds, which box should I get him?

Asked by: Vanessa
This would depend on what your veterinarian recommends, however if a pet is on the boarder of the weight range it is recommended to dose with the higher size, so 11 to 25 for your pet.
Answered by: S Duesler PharmD MBA
Date published: 2016-11-17

Can my 10 lb dog take the 11 to 25 lb dose and is my 11 lb dog getting too much at the 11 to 25 dose

Asked by: Just me
Your doctor will recommend the appropriate size for each pet. However, normally if a pet is on the boarder of the weight range, it is recommended to give the next size up for appropriate coverage. The is usually not a concern about "overdose" if your pet is one pound under.
Answered by: S Duesler PharmD MBA
Date published: 2016-11-17

 When does this medication expire

Asked by: Trudy
You will need to call our customer care department to verify this with our shipping department. Expiration dates will vary depending on our current stock.
Answered by: S Duesler PharmD MBA
Date published: 2016-11-17

My dog is over 100 pounds, what can i use that prevents heartworm, hook worm, etc.

Asked by: Freddy
You may use Sentinel, however you will be giving two tablets monthly. One of the large size up to 100 pounds and one smaller size to cover the additional weight
Answered by: S Duesler PharmD MBA
Date published: 2016-11-17

My dog is currently on heartguard and flea and tick medication. Is it safe to administer Sentinel and her flea and tick medication?

Asked by: lfrigon83
Sentinel may be administered with some flea and tick medications. Consult your veterinarian for the best choices for your pet.
Answered by: Lisa M
Date published: 2016-11-10

Does this do worms an flea prevention. Can u tell me the one that does both. She only weighs 8pd. ShihTzue 12yrold

Asked by: chub456
Sentinel is a monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs.
Answered by: Lisa M
Date published: 2016-11-10

If I am already giving my dog a heartworm pill monthly, should i steer clear of this brand since it appears to already have heartworm prevention in it? If i were to purchase this pill, would this protect fully against flea, tick and heatworm all together

Asked by: EAD21
Sentinel does not protect your pet against ticks. If you are looking for something that protects against fleas, ticks, and heartworm, you may want to look into Revolution. If you are going to use Sentinel, you should not use any other heartworm preventative with it. However, your pet will not be protected from ticks.
Answered by: Christine
Date published: 2016-10-19
  • 2016-12-07T06:05CST
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