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Proin

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2. We verify your prescription and ship your order!
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Starts $24.99 $17.99 
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Proin?

Proin is an aid in the management of urinary incontinence in dogs. Proin requires a prescription from your veterinarian, and is considered a controlled substance in Arkansas, Iowa, Louisiana and Oregon.

Proin is unavailable to be shipped to Arkansas, Iowa, Louisiana, Oregon or Internationally.

For:

Dogs

Benefits:
  • Is a supplement for urinary incontinence in dogs
  • Ensures sustained phenylpropanolamine levels in the blood stream and may help reduce the conditions often associated with high levels of phenylpropanolamine such as: decreased appetite, changes in heart rate, increased blood pressure, hyperexcitability
How it Works:

Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage.

Cautions:

Don't give Proin with ephedrine or epinephrine, and don't give it within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar. Possible side effects can occur, including restlessness, or loss of appetite, difficulty breathing, hives, and swelling of the lips, tongue, or face. If these or any other side effects occur, contact your veterinarian immediately. Proin is unavailable to be shipped to Arkansas, Iowa, Louisiana, Oregon or Internationally.

Brand Name:

Proin (PRN Pharmacal)

Generic Name:

Phenylpropanolamine

What is the most important information I should know about Proin:

Proin is a prescription medication for veterinary use in dogs. Proin is available as 25mg, 50mg and 75mg chewable, liver flavor tablets. Proin may cause restlessness, irritability, or loss of appetite.

What is Proin:

Proin is an adrenergic agent used as a supplemental product for urinary incontinence in dogs. Proin may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving Proin to my pet:

Tell your veterinarian if your pet has ever had an allergic reaction to this medication. Tell your veterinarian if your pet has glaucoma, hyperthyroid disease, diabetes, heart problems or high blood pressure. Tell your veterinarian if your pet is pregnant or lactating.

How should this medication be given:

The usual dose for dogs is 0.4-0.8mg/pound every 12 hours. Give Proin exactly as directed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Proin at room temperature away from moisture and heat. Keep this medication away from children and pets. 

What happens if I miss giving a dose:

Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose the pet:

Seek emergency veterinary medical treatment. Symptoms of overdose may include increased blood pressure, increased heart rate, seizures or coma.

What should I avoid while giving Proin to my pet:

Do not give Proin with ephedrine or epinephrine and do not give within 2 weeks of using an MAOi such as selegiline or Preventic Collar.

What are the possible side effects of Proin:

Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.

What other drugs will affect Proin:

Before giving Proin, tell your veterinarian if your pet is being given digoxin, NSAIDs such as aspirin or Rimadyl, tricyclic antidepressants such as clomipramine, and beta blockers such as atenolol, or any other prescription or over the counter medications. 

Where can I get more information:

Your pharmacist has additional information about Proin written for health professionals that you may read.

How to Use
Directions:
  • Proin liver flavored chewable tablets are available by prescription for use in dogs to treat urinary incontinence.
  • Proin may cause restlessness, irritability, or loss of appetite.
  • Tell your veterinarian about any other medication you may be giving your pet.
Tip:

Give this medication exactly as directed by your veterinarian. Do not exceed 1.8mg/lb per day. The medication may be given with food.

Dosage:
Dogs:
Weight
Dosage
All weights
The usual dose for dogs is 0.4-0.8mg/pound every 12 hours.
Cats:
Do not use!
Horses:
Do not use!
Storage:

Should be stored at room temperature away from moisture and heat. Keep this medication away from children and pets.

Ingredients
Proin Chewable Flavor Tabs 25 mg:
Active Ingredients
Strength
Phenylpropanolamine
25 mg
Proin Chewable Flavor Tabs 50 mg:
Active Ingredients
Strength
Phenylpropanolamine
50 mg
Proin Chewable Flavor Tabs 75 mg:
Active Ingredients
Strength
Phenylpropanolamine
75 mg
Customer Reviews
Proin is rated 4.7 out of 5 by 632.
Rated 5 out of 5 by from Works great This has controlled our pup's incontinence after her spaying. I would highly recommend this drug. It had zero side effects for us.
Date published: 2017-03-16
Rated 5 out of 5 by from Very satisfied We are very satisfied with our order through 1-800 pet meds. They made this process so simple, handled everything for me and the shipment came very fast. They even included a big doggy treat in the box which made my pup very happy!
Date published: 2017-03-13
Rated 5 out of 5 by from My 11 year old German Shepherd Sheila was having incontinence problems every night when she would sleep and during the day when she would nap but since starting proin from day one he has had no issues.
Date published: 2017-03-06
Rated 5 out of 5 by from it works My dog has been on this medication about 6 months now. I couldn't be happier with the results. No more accidents while she sleeps!! She doesn't care for the tablet as a "treat" but I just put it in with her dry dog food, and since she always inhales her food, gobbles it right up with everything else.
Date published: 2017-03-06
Rated 4 out of 5 by from works pretty well. don't like "chewable" tab I adopted a 1 year old cattledog who developed incontinence after spaying... mostly in her sleep. We tried incurin first and still had a lot of accidents, so changed to 25mg of PROIN 2x a day. We still had a few accidents but that got better when we started being more disciplined about timing the dose closer to 12 hours apart. I wish it was not in "chewable" form. I have to wrap it in a huge piece of hotdog or cheese to get her to eat it, which would be easier if it was a small pill vs a huge chunk. If I don't put a big enough disguise around it, she just spits it out and if I don't see it... well, then I get a puddle
Date published: 2017-03-05
Rated 5 out of 5 by from It Works For Us Lulu came from a No Kill/ no frills shelter. House breaking seemed to be going well esp. BM's. We just thought her puddles were accidents until we noticed that she dripped urine and she didn't even notice. Improvement was almost immediate with Proin. Now we are all happy, this site and service and med pricing can't be beat!
Date published: 2017-03-04
Rated 5 out of 5 by from Immediate help After our vet tried hormone therapy which had no effect on our elderly lab's dribbling accidents, she recommended Proin. I wish we had tried it first! It worked right away. I no longer find little puddles where Triscuit fell asleep and had a leaky bladder. Works great and is not expensive. She's been on it for over two years now and takes it twice a day with her food.
Date published: 2017-03-03
Rated 5 out of 5 by from Wonder product!!! Proin has made an immediate and long term difference in our dog's bed wetting. It was not only in the night, but while she was laying down through the day. The problem was getting very discouraging before this medicine. Buying it through 1800petmeds is so much cheaper than through the vet. I'm definitely sold on this med and this on-line company!
Date published: 2017-02-25
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Q&A

So my girl is almost 3 years old and recently just started leaving puddles every few hours, she will let you know that she has to go but seems as if she can't hold it, at the end of her urinating there will be a few drops of blood. would this cure her

Asked by: Bonnie18
This product will help with urinary incontinence, which will stop her from urinating out of no where.
Answered by: Ben B
Date published: 2017-03-06

Do I need a vet prescription to buy meds?

Asked by: Jorge
Yes, Proin requires a veterinarian's prescription.
Answered by: SuzyCVT
Date published: 2017-01-19

Can proin tablet be swallowed even if it's chewable

Asked by: diane
Yes, it will still be effective even if swallowed whole.
Answered by: SuzyCVT
Date published: 2017-01-12

I have a 4 month old Doberman who pees on couch, stairs, while she is just walking awAy. But she can hold it thru the night from 11pm-7am and when she is crated nothing! She was on antibiotics twice. No UTI is she old enough to try Proin???

Asked by: Tray
Proin may not be the solution you need as your dog does not seem to have urinary incontinence. Give her more time to grow up and to become fully housebroken. The urination may be a submissive behavior which she will hopefully outgrow.
Answered by: SuzyCVT
Date published: 2017-01-12

Does proin cause sleeplessness or change in behavior?

Asked by: Ellie may
Side effects of Proin include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite.
Answered by: Christine
Date published: 2017-02-24

Can I cut the chewable tablets? I currently have a prescription from the vet but they are 50 mg pills that I break in half. It's much cheaper to order here but I'm worried the chewable may he different than what I currently have.

Asked by: Britney
Yes, the chewable tablets are scored and can be easily cut in half.
Answered by: Christine
Date published: 2016-10-31

What are side effects of this medication

Asked by: Donna
Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.
Answered by: Christine
Date published: 2016-10-31

How much is the large size of Proin 50?

Asked by: Annie
Pricing depends on both the size and the strength of medication. 60-count of the 25 mg pills cost $17.99 with our "TOPTEN" coupon. Our 50 mg chewable tablets are available in 180-count and 60-count. The 180-count costs $53.99 with our "TOPTEN" coupon. 60-count of the 75 mg chewable tablets costs $26.99 with our "TOPTEN" coupon.
Answered by: Christine
Date published: 2016-10-12
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