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Proin

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Starts $24.99 $19.05 
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25 mg Chewable 60 ct
$24.99
$21.17
$19.05
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50 mg Chewable 180 ct
$74.99
$63.52
$57.17
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50 mg Chewable 60 ct
$31.24
$26.46
$23.81
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75 mg Chewable 60 ct
$37.49
$31.75
$28.58
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Proin?

Proin is an aid in the management of urinary incontinence in dogs. Proin requires a prescription from your veterinarian, and is considered a controlled substance in Arkansas, Iowa, Louisiana and Oregon.

Proin is unavailable to be shipped to Arkansas, Iowa, Louisiana, Oregon or Internationally.

For:

Dogs

Benefits:
  • Is a supplement for urinary incontinence in dogs
  • Ensures sustained phenylpropanolamine levels in the blood stream and may help reduce the conditions often associated with high levels of phenylpropanolamine such as: decreased appetite, changes in heart rate, increased blood pressure, hyperexcitability
How it Works:

Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage.

Cautions:

Don't give Proin with ephedrine or epinephrine, and don't give it within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar. Possible side effects can occur, including restlessness, or loss of appetite, difficulty breathing, hives, and swelling of the lips, tongue, or face. If these or any other side effects occur, contact your veterinarian immediately. Proin is unavailable to be shipped to Arkansas, Iowa, Louisiana, Oregon or Internationally.

Brand Name:

Proin (PRN Pharmacal)

Generic Name:

Phenylpropanolamine

What is the most important information I should know about Proin:

Proin is a prescription medication for veterinary use in dogs. Proin is available as 25mg, 50mg and 75mg chewable, liver flavor tablets. Proin may cause restlessness, irritability, or loss of appetite.

What is Proin:

Proin is an adrenergic agent used as a supplemental product for urinary incontinence in dogs. Proin may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving Proin to my pet:

Tell your veterinarian if your pet has ever had an allergic reaction to this medication. Tell your veterinarian if your pet has glaucoma, hyperthyroid disease, diabetes, heart problems or high blood pressure. Tell your veterinarian if your pet is pregnant or lactating.

How should this medication be given:

The usual dose for dogs is 0.4-0.8mg/pound every 12 hours. Give Proin exactly as directed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Proin at room temperature away from moisture and heat. Keep this medication away from children and pets. 

What happens if I miss giving a dose:

Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose the pet:

Seek emergency veterinary medical treatment. Symptoms of overdose may include increased blood pressure, increased heart rate, seizures or coma.

What should I avoid while giving Proin to my pet:

Do not give Proin with ephedrine or epinephrine and do not give within 2 weeks of using an MAOi such as selegiline or Preventic Collar.

What are the possible side effects of Proin:

Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.

What other drugs will affect Proin:

Before giving Proin, tell your veterinarian if your pet is being given digoxin, NSAIDs such as aspirin or Rimadyl, tricyclic antidepressants such as clomipramine, and beta blockers such as atenolol, or any other prescription or over the counter medications. 

Where can I get more information:

Your pharmacist has additional information about Proin written for health professionals that you may read.

How to Use
Directions:
  • Proin liver flavored chewable tablets are available by prescription for use in dogs to treat urinary incontinence.
  • Proin may cause restlessness, irritability, or loss of appetite.
  • Tell your veterinarian about any other medication you may be giving your pet.
Tip:

Give this medication exactly as directed by your veterinarian. Do not exceed 1.8mg/lb per day. The medication may be given with food.

Dosage:
Dogs:
Weight
Dosage
All weights
The usual dose for dogs is 0.4-0.8mg/pound every 12 hours.
Cats:
Do not use!
Horses:
Do not use!
Storage:

Should be stored at room temperature away from moisture and heat. Keep this medication away from children and pets.

Ingredients
Proin Chewable Flavor Tabs 25 mg:
Active Ingredients
Strength
Phenylpropanolamine
25 mg
Proin Chewable Flavor Tabs 50 mg:
Active Ingredients
Strength
Phenylpropanolamine
50 mg
Proin Chewable Flavor Tabs 75 mg:
Active Ingredients
Strength
Phenylpropanolamine
75 mg
Customer Reviews
Proin is rated 4.6567 out of 5 by 603.
Rated 5 out of 5 by from Great results! Copper is fifteen and was waking up twice a night to go outside and was leaking inside our home during the day. After one month of taking Proin, she is sleeping and we are too!
Date published: 2016-12-02
Rated 5 out of 5 by from No more leaky britches I have had my older dog on this for awhile now with good results. She is on prednisone for other issues, which causes her to drink a lot as well as urinate a lot. She would leak while resting or sleeping. Now that she has been on Proin for a while, the problem has resolved.
Date published: 2016-11-11
Rated 5 out of 5 by from Works great...and fast! My dog has and incontinence problem. There, I've set it. And pro and really works well for her. We tried another product but it didn't make a difference so we started her on prone. After taking it for just a few days, the issue cleared up. We've even been able to reduce her dosage and it still works great. We've seen no side effects either, thank goodness. And the best part about buying this product on 1800petmeds is that the price is so much better. Instead of a one month supply from our vet, I was able to buy a six-month supply on 1800petmeds.com. You just can't beat that!
Date published: 2016-11-10
Rated 5 out of 5 by from Noticeable difference!! Definitely seems to have helped, I actually noticed a change within 2-3 days!! My dog would suddenly begin whine, drop to the floor(no matter what she was in the process of doing), and begin to lick at her vaginal area what seemed like multiple times a day. It became a real issue, as she would begin to urinate when simply jumping on or off the couch, and ACCIDENTALLY(I know this because of the remorse she would show after the fact, knowing it was wrong) wet the bed nearly every night. So. To the vet we went(this time a second opinion). She was extremely helpful, and we eventually came to the conclusion that, I'm assuming because of shelter regulations, my dog had been spayed too young. Therefore, leaving her without the hormones she needed to develop correctly. After a round of antibiotics to treat for bacteria, she suggested Proin. What a huge difference!! If recommended by your vet, I'd definitely say it's worth a try. My girl seems to be much happier overall, and that's what matters to me. As for 1800petmeds, no complaints here! They kept me updated on my order, and after approval from my vet, let me know when it was shipped... it was here within a couple of days. Very happy with the product, and the company.
Date published: 2016-10-30
Rated 5 out of 5 by from Works great! This med is a miracle. We just had our area rugs cleaned in anticipation of a new baby, and didn't want to have to call them back for more wet spots. We have a 6yr old female boxer, and Proin has all but stopped her incontinence. (1 accident in 1mo vs usually 1-2x daily) Thank you to 1800PetMeds for the easy interface w/ my vet and for fast delivery!
Date published: 2016-10-24
Rated 5 out of 5 by from Works wonderfully!!! Started buying directly from my vet, but found them on here for a discount. Been buyong from PetMeds every since!!!
Date published: 2016-10-17
Rated 5 out of 5 by from Finally a solution! Shipped the day after we ordered even though it was right at 5. We got them 4 days later, and saw results right away. We have been looking for a solution for our daughter dog for far too long. So happy to have these, and for them to be affordable! Right to our door!
Date published: 2016-10-09
Rated 5 out of 5 by from amazing My 9 year old Jack Russell Terrier mix developed horrible problem with bladder control issues when sleeping/relaxed this year. It got so bad that she had to wear doggie dippers any time she slept or we would wake up huge wet spots soaked through. After just a week on this, she hasn't had any more issues. So happy because we love our little cuddle bug in bed with us at night. Highly recommend
Date published: 2016-10-03
  • 2016-12-05T06:03CST
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Q&A

Does proin cause sleeplessness or change in behavior?

Asked by: Ellie may
Side effects of Proin include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite.
Answered by: Christine
Date published: 2016-10-18

Can I cut the chewable tablets? I currently have a prescription from the vet but they are 50 mg pills that I break in half. It's much cheaper to order here but I'm worried the chewable may he different than what I currently have.

Asked by: Britney
Yes, the chewable tablets are scored and can be easily cut in half.
Answered by: Christine
Date published: 2016-10-18

What are side effects of this medication

Asked by: Donna
Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.
Answered by: Christine
Date published: 2016-10-13

How much is the large size of Proin 50?

Asked by: Annie
Pricing depends on both the size and the strength of medication. 60-count of the 25 mg pills cost $17.99 with our "TOPTEN" coupon. Our 50 mg chewable tablets are available in 180-count and 60-count. The 180-count costs $53.99 with our "TOPTEN" coupon. 60-count of the 75 mg chewable tablets costs $26.99 with our "TOPTEN" coupon.
Answered by: Christine
Date published: 2016-10-12

Can nexgard be taken with proin 

Asked by: Jr1289
Yes, NexGard can be taken with Proin.
Answered by: Christine
Date published: 2016-10-10

Great Dane is on this for weak sphincter. She now has excessive thirst. How much water should she be allowed to drink?

Asked by: Kleenix
You should give your cat as much water as she needs. You do not want to dehydrate her. This medication should help with her weak sphincter and hopefully her excess water drinking will not cause excess accidents.
Answered by: Christine
Date published: 2016-10-04

I was asked if the 50 mg PROIN is immediate release or a controlled release, where can I find this information?

Asked by: APetOwner
The 50 mg chewable tablets are immediate release.
Answered by: Christine
Date published: 2016-10-04

Can I give proin with next guard and hepato support

Asked by: Vmlps10
Yes, you can give Proin with NexGard and Hepato Support.
Answered by: Christine
Date published: 2016-10-03
  • 2016-12-05T06:24CST
  • bvseo_cps, prod_bvqa, vn_cps_3.4.0
  • cp_1, bvpage1
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  • loc_en_US, sid_prod10304, PRD, sort_recentAnswersFirst
  • clientName_1800petmeds
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