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What is the most important information I should know about PZI VET: Diabetes mellitus
is a disease where the body produces insufficient insulin. The low insulin levels may result in
high blood glucose that could produce the following changes in a cat; increased thirst,
urination and appetite; weight loss; high levels of glucose in the urine. PZI VET is not a cure
for diabetes mellitus, it can control the levels of glucose in the blood to help alleviate the
clinical signs. Follow any diet or exercise plan developed by your Veterinarian. PZI VET
What is PZI VET: Insulin is a hormone naturally produced by the
pancreas. Insulin enables the body to use the sugar in food as a source of energy. When the
body does not produce enough insulin, or when the insulin produced by the body is not effective
enough, this condition is called diabetes mellitus. This condition allows sugar levels in the
body to become very high. PZI VET is a mixture of beef and pork insulin that is used to control
hyperglycemia in cats with diabetes mellitus. PZI VET is available by prescription as a white
to off-white sterile injectable suspension that contains 40 International Units (IU) of insulin
per ml and is given to cats by subcutaneous injection.
What should I discuss with my veterinarian before giving PZI
VET: Do not give PZI VET if your cat is allergic to insulin. Before using PZI VET, tell
your veterinarian if your cat has any other medical conditions, or if your cat takes any other
prescription or over the counter medications, including vitamins, minerals, and herbal
supplements. Tell your veterinarian if your cat has any liver or kidney disease; or if your cat
is pregnant, nursing, or if you plan to breed your cat.
How should this medication be given: PZI VET should be given
according to your veterinarian¿s instructions. PZI VET is given using a U-40 syringe only. Use
of a syringe other than a U-40 syringe will result in incorrect dosing. PZI VET should not be
shaken. Just prior to use, the vial should be mixed by rolling the vial between the palms of
your hands 10 times. Do not use PZI VET if it is discolored, has particles in it, or looks
different from previous vials. Do not reuse a syringe. Dispose of all syringes in an
appropriate puncture-resistant disposal container. Dosage regimens of PZI VET will vary among
patients. The recommended starting doe is 0.1 to 0.3 units per lb every 12 to 24 hours. This
dose should be adjusted based on changes in blood glucose levels and resolution of clinical
signs. Further adjustments may be necessary with changes in the cat¿s diet, body weight or
other medications, or if the cat develops an infection, inflammation, neoplasia or an
additional endocrine or other medical disorder. Store PZI VET in the refrigerator between
36º-46º F. Do not freeze. Do not expose to direct sunlight. Keep this medication out of the
reach of children and pets.
What happens if I miss giving a dose: Follow your veterinarian¿s
directions if you miss giving a dose of PZI VET. To prevent missed doses, be sure to always
have enough PZI VET on hand.
What happens if I overdose the pet: Contact your veterinarian
immediately if you inject more than the prescribed amount of PZI VET.
What should I avoid while giving PZI VET: PZI VET should be
given to cats only. PZI VET should not be administered to humans. Calla physician immediately
if you accidentally inject yourself with PZI VET. Do not give a dose of PZI VET to a cat
experiencing an episode of low blood glucose (hypoglycemia). Common causes for hypoglycemia
include excessive doses of insulin, failure to eat, accidental doubling of insulin dose,
strenuous exercise, correction of obesity or diabetes-inducing disease, drug effects. Do not
give a dose of PZI VET if the cat has not eaten for 12 to 24 hours.
What are the possible side effects of PZI VET: Rarely, allergic
reactions to insulin can occur. Seek emergency veterinary medical attention if an allergic
reaction is experienced (difficulty breathing, swelling of the lips, tongue, or face; or
hives). Other serious side effects can occur with or without warning. The most common
insulin-related side effect is low blood sugar (hypoglycemia) with symptoms that include;
lethargy, staggering gait, seizure or coma. Contact your veterinarian immediately if your cat
has a medical problem or side effect from PZI VET therapy. Other side effects may occur. Talk
to your veterinarian about any side effect that seems unusual or bothersome to the cat.
What other drugs will affect PZI VET: PZI VET can be given with
other medications, but the dose may need to be adjusted due to the medication resulting in
either increased or decreased insulin requirements. Do not give any other prescription or over
the counter medications, including vitamins, minerals and herbal products, without first
talking to your veterinarian or pharmacist during treatment with PZI VET.
Where can I get more information: Your pharmacist has additional
information about PZI VET written for health professionals that you can read.
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