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Methigel Urinary Acidifier

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Product Info
How to Use
Customer Reviews
Product Info
What is Methigel Urinary Acidifier?

Methigel is a supplemental source of DL-Methionine and aids in maintaining a low urine pH. When combined with a proper diet, Methigel helps maintain a healthy, natural urinary tract.


Cats and Dogs (over one year of age)

  • Helps eliminate urinary tract infections
  • Treats bladder infections
  • Aids in controlling urine odors
  • Easy to administer
How it Works:

Methigel's active ingredient is DL-Methionine, an amino acid that acidifies your pet's urine. Since bacteria don't thrive in an acid environment, this helps fight infections.


Methigel should not be given to animals with severe liver, kidney or pancreatic disease. It should not be used with other urinary acidifying products. This product is not intended for use in pregnant or nursing pets. Give Methigel with food, since it may cause gastrointestinal upset when fed on an empty stomach.

Brand Name:


Generic Name:


Active ingredients per teaspoon (6 grams)


What is this product used for:

Methigel helps maintain normal urine pH, which may reduce the occurrence of crystal formation. It also helps control the odor from canine and feline urine residues.


Methigel is a non-prescription (OTC) product containing 480mg DL-Methionine per teaspoon (6 grams).

How this product should be used:

Administer orally. The usual dose in cats at least 1 year in age is teaspoonful daily. The usual dose in dogs at least 1 year in age is 1 teaspoonful daily. To stimulate taste interest, place a small amount of Methigel on your pet's nose or directly into the mouth.

What are the side effects:

Large doses of Methigel may cause gastrointestinal upset when fed on an empty stomach.

What special precautions are there:

Safe use in pregnant pets or pets intended for breeding has not been proven. If your pet's condition worsens or does not improve, stop product administration and consult your veterinarian. Administer during feeding or after your pet has eaten to reduce the incidence of gastrointestinal upset. This medication should not be given to pets with severe liver, kidney or pancreatic disease.

In the event of overdose:

Contact your veterinarian or veterinary emergency room.

How should I store this product:

Store this medication in a cool, dry place. Throw away any medication that is outdated or no longer needed. Keep this medication out of the reach of children and pets.

How to Use
  • Methigel is an extremely palatable supplemental substance. It can be given directly by mouth (see dosage below) or placed on your pet's nose to stimulate interest.

Large doses may cause gastrointestinal upset when fed on an empty stomach, so give this to your pet during or after feeding.

All weights
1 teaspoon daily
All weights
½ teaspoon daily
Do not use!

Store in a cool place.

Guaranteed Analysis per teaspoon (6 grams)
480 mg
Other Ingredients: Cane Molasses, Citric Acid, Corn Syrup, Fish Oil, Gelatin By-Products, Malt Syrup, Silicon Dioxide, Sodium Propionate (a preservative), Soybean Oil, Water, Xantham Gum.
Customer Reviews
Methigel Urinary Acidifier is rated 3.5263 out of 5 by 19.
Rated 5 out of 5 by from This is a great product that I highly recommend. My dog has had urine blockages since, a puppy. Used another product, but upset his stomach. I used this and in two days my dog was much better, with pain relief. I only keep my dog on it until his blockage is gone. He loves, loves, loves, the taste. Gently, licks off my finger. If your dog squats and finds it hard to urinate do try this product!
Date published: 2014-03-25
Rated 1 out of 5 by from Methigel Urinary Acidfier My cat won't touch it..can't blame her because it smells so bad.
Date published: 2013-11-23
Rated 4 out of 5 by from My cat loves this product It seems to work well and my cat comes running for it. My only question is judging just how much to give and not over doing a good thing.
Date published: 2013-02-25
Rated 5 out of 5 by from Methigel Urinary Acidifer I total recommend this product for any animals with urinary infections. I give this to my cat who was suffering from kidney stones and it totally worked to help him go to the bathroom and keep the pain away!
Date published: 2012-12-28
Rated 2 out of 5 by from Im sorry to say that angel wasnt happy with the product at all, it actually made her sick, so that made me question the product. i did try it again but i got the same reaction from her so i stopped giving it to her. i dont know what else to say except that i wouldnt reccomend this product. very sorry.....
Date published: 2012-09-09
Rated 4 out of 5 by from My puppy loves it! My dog loves this he gets so excited when he sees it. My dogs Vet called it "Puppy Crack"... :-D
Date published: 2012-08-15
Rated 5 out of 5 by from "Sooo-Far--Sooo-Good" This has Done The Job for my female cat who had very severe UTI #urinary tract infection#. The Vet would put her on an Anti-biotic and as soon as the Prescription was empty, she would get the infection back, and just as Severe. "It has been over seven months, since she has seen a Vet, and she has Been taking the Methigel the whole time. (NO PROBLEMS). NOTE: I read the prescribed dosage and pre-cautions, and decided that i would only administer (2) twice a week. This has worked for her. I feared the Calcium precaution, so i cut dosage and upped the amount of Calcium in her diet (food). Yes Doc's * there is a "method to my madness" regarding this APPROACH. IF THEY FORM IT IN THE "LOWER" THEY NEED IT IN THE "UPPER", digestive tracts that is. NOTE: i did Change diet to 90% soft food, along with this medication, Reducing the hard food intake. THANKS !
Date published: 2012-02-06
Rated 5 out of 5 by from Methigel is terrific My 12 y/o neutered male cat was found on ultrasound to have a 2.0 mm stone in his bladder. He absolutely refused to eat CD wet or dry but loved the Methigel and licked it off a plate. The best part is that after 6 weeks, repeat x-rays showed the stone had dissolved and was GONE. Yes, it was a small stone and Methigel wouldn't help dissolve a larger stone but this was a huge relief for both of us and we'll continue it to ensure his bladder health.
Date published: 2012-01-31
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Can this be mixed with canned food for complete consumption?
Asked by: Sandi
Large doses may cause gastrointestinal upset when fed on an empty stomach, so give this to your pet during or after feeding so mixing with canned or dry food will be fine. If it is a (picky) cat after they are done eating you can put the jell on the back of their paw. Cats are very clensy so they will start to clean (lick) the back of the paw immediately.
Answered by: James PetMeds Pro
Date published: 2015-09-30

how many doses in a tube

Asked by: rq6040
If using one teaspoon daily there will be aprox 26 doses per tube.
Answered by: Chris H, PetMedPro
Date published: 2013-07-26

how long should i give methigel urinary acidifier to my 5 year old dog for urinary infection?

Asked by: carolina10
Methigel is not used to treat a urinary infection. It is used to promote a healthy urinary tract. However, if an infection occurs, the pet will require an antibiotic. You will need to have your pet examined by your veterinarian and he/she will determine the antibiotic to use.
Answered by: Gary, Dir. of Pharmacy Services
Date published: 2012-03-05

Is it OK to use this product long term?

Asked by: Kelly
Only under the supervision of a vetinarian. If the urine ph gets too low, it can create calcium oxilate stones so monitoring ph level while using this product is my advice and your vet can help you with that.
Answered by: Kat
Date published: 2011-03-01

What should I do if I think my cat has a UT infections?

Asked by: Anonymous
Get to the vet right away! I just went through this with my male cat...he is 8....was blocked, they had to put a catheter in him for 3 days...he had a large crystal in his bladder that had caused an infection...he was in the hospital for 4 days...poor thing, but he is better now....stick to a low PH and magnesium diet for him...special diet foods are for urinary tract health, ....don't delay, take him today!!!!
Answered by: Sharon
Date published: 2013-01-10

Why was methigel discontinued?

Our dog has shown improvement using methigel . We feel this is a very good product and were very disappointed that it was discontinued by petmeds.
Asked by: Peg
We now have it again!!!!
Answered by: jenn
Date published: 2016-01-13

Does this product help prevent a urinary tract infection?

Does it prevent or can you give it to your cat when they have a urinary tract infection.
Asked by: Li
Helps eliminate urinary tract infections. When combined with a proper diet, Methigel helps maintain a healthy, natural urinary tract.
Answered by: jenn
Date published: 2013-05-17

I need this product,,now where can I get it ?

Asked by: Dave
This product has been discontinued and is no longer orderable. Sorry for the inconvenience. The alternative is Methio-Form 500 Mg 150 Tab Btl #10486 $27.99 (rx required)
Answered by: jenn
Date published: 2008-08-28
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