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Frontline Plus

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Frontline Plus?

Frontline Plus is a monthly topical flea and tick preventative for dogs and cats. Frontline Plus kills 100% of adult fleas on your pet within 12 hours and 100% of all ticks and chewing lice within 48 hours. Frontline Plus contains an insect growth regulator, S-methoprene, which kills flea eggs and larvae. It's effective against all stages of the brown dog tick, the American dog tick, the lone star tick and the deer tick (the major carrier of Lyme disease). (3 Pack = 3 doses which lasts 3 months.)

For:

Cats/Kittens and Dogs/Puppies (8 weeks of age and older)

Benefits:
  • Kills all existing fleas on your pet within 12 hours
  • Each application provides a full month of protection
  • Also aids in the control of sarcoptic mange infections in dogs
  • Great for pets that swim since it's waterproof
  • Kills ticks and chewing lice
How it Works:

Frontline Plus contains fipronil, a broad-spectrum insecticide and slow-acting poison that disrupts the central nervous system of fleas and ticks and S-Methoprene, an insect growth regulator that kills flea eggs and larvae. The active ingredients are stored in the sebaceous glands and are wicked out of the hair follicles and continuously re-applied to the coat for long-lasting, waterproof protection.

Cautions:

Your pet may experience some temporary irritation at the site of application. If signs persist or become severe within a few days of application, consult your veterinarian immediately.

Brand Name:

Frontline Plus (Merial)

Generic Name:

Fipronil, S-methoprene

What is Frontline Plus used for:

Frontline Plus provides convenient and effective flea and tick control in dogs and cats, puppies and kittens. It is effective against all stages of the brown dog tick, the American dog tick, lone star tick and deer ticks (the major carrier of Lyme disease). It also kills flea eggs and flea larvae. Frontline Plus rapidly eliminates infestations with chewing lice. Frontline Plus for Dogs and Puppies also aids in the control of sarcoptic mange infections.

Availability of Frontline Plus:

Frontline Plus is a non-prescription (OTC) product.

How Frontline Plus should be used:

Use Frontline Plus for Dogs (fipronil 9.8% and S-methoprene 8.8%) on dogs and puppies 8 weeks or older. Frontline Plus for Dogs is available as 0.67 ml applicators for use on dogs and puppies up to 22 lbs, 1.34 ml applicators for dogs 23-44 lbs, 2.68 ml applicators for dogs 45-88 lbs and 4.02 ml applicators for dogs 89-132 lbs. Wait 24 hours to fully dry before swimming or bathing. Do not reapply for 30 days. Use Frontline Plus for Cats (fipronil 9.8% and S-methoprene 11.8%), available as 0.5 ml applicators, on cats and kittens 8 weeks or older. Place the applicator tip through the animal's hair to the skin level between the shoulder blades. Apply the entire contents of the applicator in a single spot to the animal's skin. Use only one applicator per treatment.

What are the side effects of Frontline Plus:

Pets may experience some temporary irritation at the site of product application. If signs persist or become more severe within a few days of application, consult a veterinarian immediately.

What special precautions are there for Frontline Plus:

This product is for external use on dogs and puppies, cats and kittens 8 weeks or older. Frontline Plus is approved for use on breeding, pregnant, or nursing animals. Consult a veterinarian before using on medicated animals, animals using this product with other pesticides, and debilitated, or aged animals. This product is flammable. Keep away from heat and open flame. This product is harmful to humans if swallowed. Call a physician or poison control center for advice. Have patient sip water do not induce vomiting unless advised to and patient is conscious. This product can cause eye injury. Flush eyes with plenty of water. Call a physician if irritation persists. Avoid contact with skin, eyes or clothing. Wash thoroughly with soap and water after handling.

In the event of a Frontline Plus overdose:

Contact your veterinarian or veterinary emergency room.

How should I store Frontline Plus:

Store this product at room temperature. Store in the original container only. To dispose wrap original container in several layers of newspaper and discard in trash. Keep out of the reach of children and pets.

How to Use
Directions:
  • Remove the Frontline Plus applicator from the child-resistant package. You can use scissors to snip the foil, or pull the tab to remove the applicator.
  • Snap open the tip of the Frontline applicator - away from your body and face.
  • Part your pet's hair between the shoulder blades until you can see the skin, and place the tip of the applicator on the skin.
Tip:

Wait until application site is fully dry (usually 24 hours) before bathing your pet or letting your pet go swimming.

Dosage:
Dogs/Puppies: (8 weeks of age or older)
Weight
Dosage
Up to 22 lbs
Apply contents of 1 applicator once a month (0.67 ml)
23-44 lbs
Apply contents of 1 applicator once a month (1.34 ml)
45-88 lbs
Apply contents of 1 applicator once a month (2.68 ml)
89-132 lbs
Apply contents of 1 applicator once a month (4.02 ml)
Cats/Kittens: (8 weeks of age or older)
Weight
Dosage
All weights
Apply contents of 1 applicator once a month (0.5 ml)
Horses:
Do not use!
Storage:

Should be stored at room temperature.

Ingredients
Frontline Plus for Dogs & Puppies 8 weeks or older and up to 22 lbs:
Active ingredients (per 0.67 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 23-44 lbs:
Active ingredients (per 1.34 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 45-88 lbs:
Active ingredients (per 2.68 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 89-132 lbs:
Active ingredients (per 4.02 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Cats & Kittens 8 weeks or older:
Active ingredients (per 0.50 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
11.8%
Customer Reviews
Frontline Plus is rated 3.4331 out of 5 by 3,960.
Rated 1 out of 5 by from DOES NOT WORK!!!! I purchased Frontline Plus and it did not work at all! The fleas seem quite happy, active and my 2 dogs are scratching itching more that before I used the product! I actually see more fleas and flea debris on my dogs than before I applied the produt.
Date published: 2017-01-11
Rated 5 out of 5 by from Great flea/tick control product! No dog my family or I ever owned had a flea/tick problem as long as we used this product. I live in the Midwest, so I do not need to use it during winter months, but in milder climates, owners should use this year-round to prevent fleas/ticks.
Date published: 2017-01-08
Rated 1 out of 5 by from Waste of money! I started using this for my dogs and cat (trying to save money) and soon after I started seeing fleas on them. I spent several months trying all sorts of tricks and remedies and flea sprays on my dogs and my house thinking I had done something wrong, but none worked. Finally, I switched the flea treatment to Advantage II. NO MORE FLEAS!!!! Lesson: Frontline is a waste of money that doesn't work. Just spend the extra $$ to get quality flea prevention that works. I highly recommend any other brand.
Date published: 2017-01-08
Rated 5 out of 5 by from Works well for our Yorkie We used this product for years, then I tried the generic brand to save a little money. After finding fleas on our dog on two separate occasions I went back to Frontline. Hands down worth the extra money. No more fleas!
Date published: 2017-01-02
Rated 5 out of 5 by from Got the fleas fleeing! With 4 cats and a greyhound, you can imagine the problems with fleas. Frontline is a great product and we're all flealess.
Date published: 2016-12-30
Rated 5 out of 5 by from FRONTLINE PLUS is like insect armor for pets I have used many many different flea and tick products over the years on our pets. We've tried the different brand names and generic; topical and ingested controls. We have currently have 7 dogs and 2 cats, varying in ages and size... all flea & tick FREE thanks to Frontline Plus. I have not found any other product yet that seems to work as well for as long a time, and with no side effects yet experienced by any of my pets. It is more pricey than the competition, so I've had to settle for less protection for my fur babies from time to time when money is scarce. But when I'm able to afford it, this is the one I always choose.
Date published: 2016-12-21
Rated 5 out of 5 by from Great Products I have been using frontline plus for large dogs for a few years now. I have never found a flea on my dog since using. I amwell pleased with, i wouldn't use any thing else!!
Date published: 2016-12-16
Rated 2 out of 5 by from Not working anymore! Hi, I have a complaint about the past Frontline Plus I've purchased in the last couple of months. I have gotten the 3 pack, with one for my 10 lb dog and one for my 80 lb dog. Both the correct doses for their weight. But the product isn't doing its job at all! I have NEVER had an issue with fleas until now! It is NOT killing them or working at all that I can see. My dogs have fleas for the first time and they've always been on Frontline Plus! But these last packs I've purchased aren't doing anything to get rid of, or kill, or prevent fleas! Has something changed with Frontline?!? I'm very disappointed as we've never had an issue with fleas or Frontline Plus. And nothing has changed on our part to warrant having fleas.
Date published: 2016-12-08
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Q&A

My cat weighs 20lbs and it seems like only 1 dose doesn't work. Can i use 2 would it hurt him? I put it on him about 2 weeks ago

Asked by: Michelle
Adult fleas that are living ON your pet are the last 5% of the lifecycle and population of the flea. Seriously, if you find one adult flea on your pet and they spend any amount of time indoors, you have A LOT of fleas in your house (eggs, larvae, pupae). Hit them hard and go all out. Treat all pets at the same time. Vacuum everything. Throw the vacuum bags directly in a trash bag and close it. Bomb the whole house. Do the same thing in a month (and continue if needed). It sounds like a lot of work (and money), but trust me it will end up being 10x that if you don't.
Answered by: vernzimm
Date published: 2017-01-14

For what size dog is Frontlibe Plus Lot no. A48501?

Asked by: Robby
We are very sorry, we do not have a way of checking the size by the lot number. However if the application is still in the foil package the maximum size is printed on the back.
Answered by: Amy Petmed Pro
Date published: 2017-01-10

I lost the box and only have the applicators. what size is this for dog 88 0.091 fl oz lot no L60704

Asked by: kelly
Dogs 45-88lbs
Answered by: Amy Petmed Pro
Date published: 2016-12-29

Do I have this right? I have 2 Irish Wolfhounds. Our male is 154lbs & our female is 130-ish. She getssssst 1 dose and my male would get... 1 dose of the 89-132 AND one dose of 11 -22? So I have to buy multiple boxes. Seems excessive. Is there an easier wa

Asked by: Wolfhoundhairdontcare
Yes you have it correct! The manufacturer recommends to use 2 packages for your furry friend weighing over 132lbs to accommodate his weight.
Answered by: Amy Petmed Pro
Date published: 2016-12-20

Can this be used on pregnant dog close to due date of delivery

Asked by: Lottie
Frontline Plus is approved for use on breeding, pregnant, or nursing animals
Answered by: Amy Petmed Pro
Date published: 2016-12-20

I'd like to know about frontline plus for cats 

Asked by: Cooley bug
Frontline Plus for cats kills adult, egg, and larvae of fleas and also kills ticks. You will use 1 tube per month and have the option of getting 3 months, 6 months, or a 12 month supply.
Answered by: Carolyn Petmed Pro
Date published: 2016-12-02

When was Frontline first made? And when will it be updated so that the super fleas are not immune to it anymore?

Asked by: achilles
Merial, the company that makes Frontline Plus, is the best source for answers to your questions.
Answered by: Lisa M
Date published: 2016-11-22

Are these 3 packs?

Asked by: Lenny
The frontline plus is available in 3 packs, 6 packs, and 12 packs.
Answered by: Cherley Petmeds Pro
Date published: 2016-11-17
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