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Frontline Plus

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Frontline Plus?

Frontline Plus is a monthly topical flea and tick preventative for dogs and cats. Frontline Plus kills 100% of adult fleas on your pet within 12 hours and 100% of all ticks and chewing lice within 48 hours. Frontline Plus contains an insect growth regulator, S-methoprene, which kills flea eggs and larvae. It's effective against all stages of the brown dog tick, the American dog tick, the lone star tick and the deer tick (the major carrier of Lyme disease). (3 Pack = 3 doses which lasts 3 months.)

For:

Cats/Kittens and Dogs/Puppies (8 weeks of age and older)

Benefits:
  • Kills all existing fleas on your pet within 12 hours
  • Each application provides a full month of protection
  • Also aids in the control of sarcoptic mange infections in dogs
  • Great for pets that swim since it's waterproof
  • Kills ticks and chewing lice
How it Works:

Frontline Plus contains fipronil, a broad-spectrum insecticide and slow-acting poison that disrupts the central nervous system of fleas and ticks and S-Methoprene, an insect growth regulator that kills flea eggs and larvae. The active ingredients are stored in the sebaceous glands and are wicked out of the hair follicles and continuously re-applied to the coat for long-lasting, waterproof protection.

Cautions:

Your pet may experience some temporary irritation at the site of application. If signs persist or become severe within a few days of application, consult your veterinarian immediately.

Brand Name:

Frontline Plus (Merial)

Generic Name:

Fipronil, S-methoprene

What is Frontline Plus used for:

Frontline Plus provides convenient and effective flea and tick control in dogs and cats, puppies and kittens. It is effective against all stages of the brown dog tick, the American dog tick, lone star tick and deer ticks (the major carrier of Lyme disease). It also kills flea eggs and flea larvae. Frontline Plus rapidly eliminates infestations with chewing lice. Frontline Plus for Dogs and Puppies also aids in the control of sarcoptic mange infections.

Availability of Frontline Plus:

Frontline Plus is a non-prescription (OTC) product.

How Frontline Plus should be used:

Use Frontline Plus for Dogs (fipronil 9.8% and S-methoprene 8.8%) on dogs and puppies 8 weeks or older. Frontline Plus for Dogs is available as 0.67 ml applicators for use on dogs and puppies up to 22 lbs, 1.34 ml applicators for dogs 23-44 lbs, 2.68 ml applicators for dogs 45-88 lbs and 4.02 ml applicators for dogs 89-132 lbs. Wait 24 hours to fully dry before swimming or bathing. Do not reapply for 30 days. Use Frontline Plus for Cats (fipronil 9.8% and S-methoprene 11.8%), available as 0.5 ml applicators, on cats and kittens 8 weeks or older. Place the applicator tip through the animal's hair to the skin level between the shoulder blades. Apply the entire contents of the applicator in a single spot to the animal's skin. Use only one applicator per treatment.

What are the side effects of Frontline Plus:

Pets may experience some temporary irritation at the site of product application. If signs persist or become more severe within a few days of application, consult a veterinarian immediately.

What special precautions are there for Frontline Plus:

This product is for external use on dogs and puppies, cats and kittens 8 weeks or older. Frontline Plus is approved for use on breeding, pregnant, or nursing animals. Consult a veterinarian before using on medicated animals, animals using this product with other pesticides, and debilitated, or aged animals. This product is flammable. Keep away from heat and open flame. This product is harmful to humans if swallowed. Call a physician or poison control center for advice. Have patient sip water do not induce vomiting unless advised to and patient is conscious. This product can cause eye injury. Flush eyes with plenty of water. Call a physician if irritation persists. Avoid contact with skin, eyes or clothing. Wash thoroughly with soap and water after handling.

In the event of a Frontline Plus overdose:

Contact your veterinarian or veterinary emergency room.

How should I store Frontline Plus:

Store this product at room temperature. Store in the original container only. To dispose wrap original container in several layers of newspaper and discard in trash. Keep out of the reach of children and pets.

How to Use
Directions:
  • Remove the Frontline Plus applicator from the child-resistant package. You can use scissors to snip the foil, or pull the tab to remove the applicator.
  • Snap open the tip of the Frontline applicator - away from your body and face.
  • Part your pet's hair between the shoulder blades until you can see the skin, and place the tip of the applicator on the skin.
Tip:

Wait until application site is fully dry (usually 24 hours) before bathing your pet or letting your pet go swimming.

Dosage:
Dogs/Puppies: (8 weeks of age or older)
Weight
Dosage
Up to 22 lbs
Apply contents of 1 applicator once a month (0.67 ml)
23-44 lbs
Apply contents of 1 applicator once a month (1.34 ml)
45-88 lbs
Apply contents of 1 applicator once a month (2.68 ml)
89-132 lbs
Apply contents of 1 applicator once a month (4.02 ml)
Cats/Kittens: (8 weeks of age or older)
Weight
Dosage
All weights
Apply contents of 1 applicator once a month (0.5 ml)
Horses:
Do not use!
Storage:

Should be stored at room temperature.

Ingredients
Frontline Plus for Dogs & Puppies 8 weeks or older and up to 22lbs:
Active ingredients (per 0.67 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 23-44 lbs:
Active ingredients (per 1.34 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 45-88 lbs:
Active ingredients (per 2.68 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 89-132 lbs:
Active ingredients (per 4.02 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Cats & Kittens 8 weeks or older:
Active ingredients (per 0.50 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
11.8%
Customer Reviews
Frontline Plus is rated 3.4327 out of 5 by 3,952.
Rated 5 out of 5 by from Easy to apply and works great I have used this product on 6 dachshunds over the past 40 years and never had a problem with it. I have never had fleas using this product and use it as directed, once a month.
Date published: 2016-11-29
Rated 5 out of 5 by from Best product for addressing ticks and fleas! I used other, less expensive products that weren't as strong and pets got fleas, a problem which ended up costing more to address.
Date published: 2016-11-24
Rated 1 out of 5 by from Does not work Applied this to my kitty and she still has fleas. Checked box for expiration date and found none, so I'm wondering if I was sold an expired product:( I've bought frontline in the past from my veterinarian and never had a problem and there was always an expiration date on package. Guess I'll go back to my vet. Very disappointed
Date published: 2016-11-24
Rated 5 out of 5 by from I needed medicine my vet did not have They were so helpful and quick to deliver the medicine
Date published: 2016-11-22
Rated 5 out of 5 by from Frontline Flea & Tick We have been using Frontline for our PWD since she was a puppy. She has a sensitive body so we apply only 1/2 of the tube for 2 weeks & the remaining 1/2 at 2 weeks. It just keeps her covered with not the harsh chemical affect. It has worked great for 9 1/2 years.
Date published: 2016-11-17
Rated 5 out of 5 by from They make taking care of my best friend so easy. . I purchased Frontline Plus for the first time this year and was really pleased with the price and the results. . when the time came for a new three pack I was messing around. .PetMeds kept reminding me, and so I said no big deal, and ordered my Frontline for my dog, Maggie, a rescue who will be 12 in January, and my cat Nikki. They made sure my fur kids are safe and taken care of. They also sent a special bone which Maggie for the FIRST TIME EVER. . buried in her bed??? Yes, she did. She loved that bone, a gift from PetMeds, so when I placed my order I ordered a box for her. That is her "special treat". .she knows when I give her that, no more food and time for bed for both of us. . . Thank you PetMeds for making it so easy and affordable to take care of my fur kids. .
Date published: 2016-11-08
Rated 5 out of 5 by from Great product! I've been using this on my yellow lab every month since we got her @ 3 mos. old. She is now over 13 yrs. old. She's never had a problem with fleas or ticks. I've never tried any other brand, because this has always worked.
Date published: 2016-11-04
Rated 1 out of 5 by from Does not work Frontline Plus does not work anymore on my outdoor barn cats. The formula is not the same or the fleas have become immune to this product. Will try Adavantage ll next.
Date published: 2016-11-03
  • 2016-12-06T06:03CST
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Q&A

I'd like to know about frontline plus for cats 

Asked by: Cooley bug
Frontline Plus for cats kills adult, egg, and larvae of fleas and also kills ticks. You will use 1 tube per month and have the option of getting 3 months, 6 months, or a 12 month supply.
Answered by: Carolyn Petmed Pro
Date published: 2016-12-02

My cat weighs 20lbs and it seems like only 1 dose doesn't work. Can i use 2 would it hurt him? I put it on him about 2 weeks ago

Asked by: Michelle
Hi there, you have to wait a minimum of 3 weeks to dose your Furry Friends again (unless directed differently from your vet). Just a heads up, if you are dealing with a flea issue in the house or an issue outside, just treating the pets alone will not resolve this and you will constantly have an issue. So you may have to use a fogger in the house or treat the outside grass to help get the flea issue under control.
Answered by: James PetMeds Pro
Date published: 2016-12-01

When was Frontline first made? And when will it be updated so that the super fleas are not immune to it anymore?

Asked by: achilles
Merial, the company that makes Frontline Plus, is the best source for answers to your questions.
Answered by: Lisa M
Date published: 2016-11-22

Are these 3 packs?

Asked by: Lenny
The frontline plus is available in 3 packs, 6 packs, and 12 packs.
Answered by: Cherley Petmeds Pro
Date published: 2016-11-17

Do u take care credit

Asked by: Tami
We are sorry we do not accept Care Credit.
Answered by: Carolyn Petmed Pro
Date published: 2016-11-15

What if some of it get on your cats hair? 

Asked by: Momof2
Frontline Plus should be applied to the skin for maximal absorption, and not the hair. The medication needs to get absorbed through the skin to work to protect your pet.
Answered by: Christine
Date published: 2016-10-22

Does the retail box arrive in a sealed blister pack such as I would find it in at Walmart, Target, and most other brick & mortar stores? Thanks.

Asked by: Jim B
Yes, Frontline Plus comes in its original package.
Answered by: Christine
Date published: 2016-10-19

After applying how long does it take to start working 

Asked by: Kay 53
Frontline Plus kills 100% of adult fleas on your pet within 12 hours and 100% of all ticks and chewing lice within 48 hours.
Answered by: Christine
Date published: 2016-10-19
  • 2016-12-06T06:06CST
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