When liver function is compromised, the exact cause can often be difficult to determine. Support of the liver, regardless of the cause, is essential if function is to be improved. Denosyl has been shown to markedly increase glutathione levels in the liver of dogs and cats. Denosyl activity goes far beyond just increasing glutathione levels. It has been shown to protect liver cells from cell death and may be useful in cell repair and healing. Denosyl contains a stable salt of S-Adenosylmethionine.
Denosyl is a daily supplement that helps support proper liver function. Its main ingredient is S-Adenosylmethionine (SAMe). By increasing the levels of a key antioxidant, Denosyl may help protect and repair liver cells.
For: Cats and Dogs
Benefits:
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Increases glutathione levels, an important antioxidant that protects your pet’s cells from dangerous toxins
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Improves a pet’s liver health
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No reported side effects
How it works: Denosyl has been shown to increase the level of glutathione, an antioxidant that can fight deadly toxins in your pet’s body. For optimal absorption, it should be taken on an empty stomach.
Cautions: Denosyl tablets must be given to your pet whole. Store this product in a cool and dry place. Keep tablets in the original blister pack until they are used.
More Information:
Brand Name Denosyl (Nutramax)
Active Ingredient(s): S-Adenosylmethionine
What is this product used for: Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidant that protects liver cells from toxins and death. Denosyl is recommended to improve hepatic glutathione levels in compromised animals to help maintain and protect liver function.
Availability: Denosyl is a non-prescription (OTC) product available as 90mg, 225mg and 425mg stabilized tablets.
How this product should be used: The tablets should be given on an empty stomach at least one hour before feeding. Research shows that, if possible, a fasting period of 8-12 hours before giving this product is optimal. The usual dose in cats and dogs is based on weight. For pets up to 12 lbs give 1 tablet of the 90mg strength, for pets 13 to 34 lbs give 1 tablet of the 225mg strength, for pets 35 to 65 lbs give 1 tablet of the 425mg strength, for pets 66 to 120 lbs give 2 tablets of the 425mg strength and for pets over 120 lbs give 3 tablets of the 425mg strength. When giving more than 1 tablet the total number of tablets may be divided into morning and evening. For example, a dose of 3 tablets could be divided into 2 tablets in the morning and 1 tablet in the evening.
What are the side effects: There are no reported side effects.
What special precautions are there: Tablets must be given whole. Do not break or split. Research shows that this product may be of benefit to pets that are also taking primidone, Phenobarbital, prednisone, azathioprine, cyclosporine and certain anti-depressants.
In the event of overdose: Contact a veterinarian or veterinary emergency room.
How should I store this product: Store this product in a cool, dry, place. Keep tablets in the original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled. Keep out of the reach of children.
Directions:
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Denosyl is a Liver Support Formula.
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Denosyl is available for small dogs and cats, medium dogs, and large dogs.
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Do not crush or break the tablet as this will damage the tablet’s enteric coat and inhibit absorption.
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Do not remove tablets from blister pack until ready to use.
Tip: Denosyl should be given on an empty stomach at least one hour before feeding. If giving more than 1 tablet divide the daily dose between morning and evening.
Dosage:
Pet
Weight
Dosage
Small Dogs and Cats – Denosyl (90 mg)
Up to 12 lbs
Give 1 tablet daily
Medium Dogs – Denosyl (225 mg)
13-34 lbs
Give 1 tablet daily
Large Dogs – Densoyl (425 mg)
35-65 lbs
Give 1 tablet daily
66-120 lbs
Give 2 tablets daily
121 lbs and over
Give 3 tablets daily
Horses:
Storage: Should be stored in a cool dry place. Do not refrigerate.
Denosyl for Cats and Small Dogs:
Active Ingredients (up to 12 lbs)
Amount
S-Adenosylmethionine
90 mg
Denosyl for Medium Dogs:
Active Ingredients (13-34 lbs)
Amount
S-Adenosylmethionine
25 mg
Denosyl for Larger Dogs:
Active Ingredients (35 lbs and over)
Amount
S-Adenosylmethionine
425 mg
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.
