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Comfortis

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Comfortis?

Comfortis is the first FDA-approved, chewable beef-flavored tablet that kills fleas and prevents flea infestations on dogs and cats for a full month. Comfortis for Dogs & Cats requires a prescription from your veterinarian.

For:

Dogs & Cats (14 weeks of age or older)

Benefits:
  • Starts killing fleas within 30 minutes
  • Lasts a full month
  • Kills fleas before they can lay eggs
  • Comes in a convenient chewable, beef-flavored tablet
  • Spinosad, the active ingredient in Comfortis, is environmentally friendly
How it Works:

Spinosad kills fleas by causing excitation of the insect's nervous system, leading to paralysis and rapid death.

Cautions:

Side effects may occur, including vomiting. If your pet is experiencing loss of appetite, lethargy, or any other difference in behavior, contact your veterinarian. The FDA has received reports of adverse reactions in dogs receiving the drug Comfortis (spinosad) concurrently with high, extra-label doses of ivermectin. Dogs receiving extra-label doses of ivermectin to treat non-responsive demodectic mange and other conditions have developed signs of ivermectin toxicity. Ivermectin is an ingredient found in heartworm preventatives such as Heartgard Plus, Heartgard, Iverhart Plus and Ivomec. In cats, the most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin.

Brand Name:

Comfortis (Lilly)

Generic Name:

Spinosad

What is Comfortis:

Comfortis is a chewable, synthetic beef flavored tablet (derived from pork protein and hydrolyzed soy) that is given to a dog or cat to kill fleas and prevent flea infestations for one month. Comfortis chewable tablets are for monthly use in dogs and puppies or cats and kittens 14 weeks of age and older.

What should I discuss with my veterinarian before giving Comfortis to my pet:

Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog or cat has a history of seizures (epilepsy).

What is the most important information I should know about Comfortis:

Comfortis is a prescription medication FDA approved for use in dogs and puppies and cats and kittens 14 weeks of age or older to kill fleas and prevent flea infestations for one month. Comfortis is available in a Yellow box for dogs 3.3 to 4.9 lbs and cats 2-4 lbs (90mg), Pink box for dogs 5 to 10 lbs and cats 4-6 lbs (140mg), Orange box for dogs 10.1 to 20 lbs and cats 6.1-12 lbs (270mg), Green box for dogs 20.1 to 40 lbs and cats 12.1-24 (560mg), Blue box for dogs 40.1 to 60 lbs (810mg), and Brown box for dogs 60.1 to 120 lbs (1620mg). Please note: Cats over 24 lbs should be administered the appropriate combination of tablets.

How should this medication be given:

Give Comfortis chewable tablets with food. Give Comfortis chewable tablets once a month. Comfortis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose the pet with another full dose. Store Comfortis at room temperature (68-77° F)

What should I avoid while giving Comfortis:

Your pet may maintain normal activities and interactions while being given Comfortis. The safe use of Comfortis in breeding, pregnant, or lactating cats and dogs has not been evaluated.

What are the possible side effects of Comfortis:

Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Comfortis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to the pet.

What other drugs will affect Comfortis:

Talk to your veterinarian before giving any prescription or over the counter medications.

How to Use
Directions:
  • Comfortis is a prescription medication used in dogs to kill fleas and prevent flea infestations for 1 month.
  • Comfortis chewable tablets are beef flavored.
  • Comfortis can be given to dogs at least 14 weeks of age, weighing at least 3.3 lbs, and cats 14 weeks of age, weighing at least 2 lbs.
Tip:

If vomiting occurs within 1 hour of administration, redose the pet with another tablet.

Dosage:
Dogs/Puppies: (14 weeks of age or older)
Weight
Dosage
3.3-4.9 lbs (Yellow Box)
Give one 90mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
5-10 lbs (Pink Box)
Give one 140mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
10.1-20 lbs (Orange Box)
Give one 270mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
20.1-40 lbs (Green Box)
Give one 560mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
40.1-60 lbs (Blue Box)
Give one 810mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
60.1-120 lbs (Brown Box)
Give one 1620mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
Over 120 lbs
Give the appropriate combination of tablets
Cats/Kittens: (14 weeks of age or older)
Weight
Dosage
2-4 lbs (Yellow Box)
Give one 90mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
4-6 lbs (Pink Box)
Give one 140mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
6.1-12 lbs (Orange Box)
Give one 270mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
12.1-24* lbs (Green Box)
Give one 560mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
Horses:
Do not use!
Storage:

Store Comfortis at room temperature (68°-77° F).

Ingredients
Comfortis for Dogs: 3.3-4.9 lbs - Comfortis for Cats: 2-4 lbs (Yellow Box)
Active Ingredient
Amount
Spinosad
90 mg
Comfortis for Dogs: 5-10 lbs - Comfortis for Cats: 4-6 lbs (Pink Box)
Active Ingredient
Amount
Spinosad
140 mg
Comfortis for Dogs 10.1-20 lbs - Comfortis for Cats: 6.1-12 lbs (Orange Box)
Active Ingredient
Amount
Spinosad
270 mg
Comfortis for Dogs 20.1-40 lbs - Comfortis for Cats: 12.1-24 lbs (Green Box)
Active Ingredient
Amount
Spinosad
560 mg
Comfortis for Dogs 40.1-60 lbs (Blue Box)
Active Ingredient
Amount
Spinosad
810 mg
Comfortis for Dogs 60.1-120 lbs (Brown Box)
Active Ingredient
Amount
Spinosad
1,620 mg
Customer Reviews
Comfortis is rated 4.5349264705882355 out of 5 by 1,088.
Rated 5 out of 5 by from Great stuff! I have been using Comfortis for my dogs for years. It works great!
Date published: 2016-07-26
Rated 1 out of 5 by from Did not work. I turned to comfortis because it was one of the best flea medication. Everything else I have tried for flea killing and prevention never worked. The comfortis didn't either. I didn't know it wasn't working until I called my vet and symptoms showed that the medicine didn't work on my furbaby.
Date published: 2016-07-23
Rated 5 out of 5 by from Flee free at last Having a little dog that likes to play outside is amazing, but not when she is pure white and gets fleas like no other. I was trying everything, I was bathing her everyday, sometimes twice and all that was doing was making her lose her hair. So my grandmas dog has been using this pill for a while and I asked her about it. She ended up giving me one of the pills because she saw I was struggling so much. Well, within like 50 minutes, the fleas were literally just coming off of her, dead! I plan on buying some more of these pills when I can afford them but, I definitely recommend. I had a miserable fur baby and now she's back to her fun loving self and can run around outside as much as she wants!!
Date published: 2016-07-13
Rated 5 out of 5 by from Miracle for English Bulldogs With a crew of bullies , we were struggling with a horrible infestation of fleas ! Needed immediate results -- within a few hours , relief is on the way !! Hands down , the best choice thus far !!
Date published: 2016-07-12
Rated 5 out of 5 by from Best Flea Medicine Period! Hands down nothing compares to comfortis. It last a whole month and has no side effects on my Boston Terrier.
Date published: 2016-07-10
Rated 5 out of 5 by from Flea Free This product uses an insecticide that works as a systemic flea killer. Our cat is doing well and is free of fleas. For some cats the topical flea applications work well, but our cat had a skin reaction that made her hair fall out. She looked horrible. Comfortis is a good alternative and now her hair is growing back. I crumbled the pill into a can of her favorite canned pet food. Follow directions on the package for good results.
Date published: 2016-06-15
Rated 5 out of 5 by from Comfortis really works! I gave my pug his second dose about a week ago. I have not seen a single flea on him in over a month. I've tried other products which either didn't work or had unacceptable side effects. My parents also use Comfortis on their corgi and have had equally great results.
Date published: 2016-06-11
Rated 5 out of 5 by from No Skin Issues With This!!! English Bulldog This is the only product that I can give either of my English Bulldogs that doesn't make their hair fall out and sores on their skin!! We tried other products that have the "all in one pill" deal and the next day they started loosing clumps of hair!!! It was terrible! Comfortis is definitely the best thing for us!! No fleas and no problems!!
Date published: 2016-05-29
  • 2016-07-28T06:03CST
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Q&A

do i Need a prescription for it and is it save of a kittie

Asked by: Gema
Comfortis does require a prescription and it is safe to give to kittens/cats, but always talk to your veterinarian about any problems your pet has(i.e. seizures) before getting a prescription.
Answered by: paulpharmacistintern
Date published: 2016-07-27

When can I bathe my dog after giving comfortis?

Asked by: Mannie
You can bathe your dog anytime after giving the medication.
Answered by: paulpharmacistintern
Date published: 2016-07-26

After giving pill how long do I need to wait to bathe my dog ?

Asked by: Melanie
With Comfortis you can bathe your dog at any time.
Answered by: paulpharmacistintern
Date published: 2016-07-26

How long after the pill do I have to wait to Give my boy a bath felony melanie

Asked by: Felonymelanie
There is no wait time needed for a bath after giving Comfortis.
Answered by: paulpharmacistintern
Date published: 2016-07-26

Can I give this to my ferret?

Asked by: Susta31
Thank you for your question. This product is for cats or dogs.
Answered by: James PetMeds Pro
Date published: 2016-07-21

Is comfortis good to use for tick infestation 

Asked by: Dee dub
No tick prevention or coverage from ticks PERIOD! It's very unfortunate because it works like a flea/flea infestation miracle almost instantly!
Answered by: LuvmyEli
Date published: 2016-07-02

Do you start comfortis before fleas are seen

Asked by: mona
Comfortis is a once a month flea prevention that is given year round, please speak with your veterinarian and discuss if this medication is right for your pet.
Answered by: Pharmacy Manager
Date published: 2016-04-17

Will this product kill ticks on dogs?

Asked by: redboy
Comfortis is a chewable, synthetic beef flavored tablet that is given to a dog or cat to kill fleas and prevent flea infestations for one month. Comfortis is not effective against ticks. We do have Nexgard chewables available which is a brand new, revolutionary flea and tick preventative from the makers of Frontline®, the #1 choice of veterinarians. It's the first flea and tick killer of its kind because it comes in a yummy, beef-flavored soft chew that protects your dog from a flea and tick infestation for a full 30 days. You may click on the link below to view the Nexgard, Here is the link: http://www.1800petmeds.com/NexGard+Chewables-prod10356.html?q=nexgard
Answered by: Cherley Petmeds Pro
Date published: 2016-03-21
  • 2016-07-28T06:05CST
  • bvseo_cps, prod_bvqa, vn_cps_3.3.0
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