Comfortis is the first FDA-approved, chewable beef-flavored tablet that kills fleas and prevents flea infestations on dogs for a full month. Comfortis for Dogs requires a prescription from your veterinarian.
For: Dogs (14 weeks of age or older)
Benefits:
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Starts killing fleas within 30 minutes
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Lasts a full month
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Kills fleas before they can lay eggs
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Comes in a convenient chewable, beef-flavored tablet
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Spinosad, the active ingredient in Comfortis, is environmentally friendly
How it works: Spinosad kills fleas by causing excitation of the insect’s nervous system, leading to paralysis and rapid death.
Cautions: Side effects may occur, including vomiting. If your pet is experiencing loss of appetite, lethargy, or any other difference in behavior, contact your veterinarian. The FDA has received reports of adverse reactions in dogs receiving the drug Comfortis (spinosad) concurrently with high, extra-label doses of ivermectin. Dogs receiving extra-label doses of ivermectin to treat non-responsive demodectic mange and other conditions have developed signs of ivermectin toxicity. Ivermectin is an ingredient found in heartworm preventatives such as Heartgard Plus, Heartgard, Iverhart Plus and Ivomec.
More Information:
Brand Name Comfortis (Lilly)
Generic Name Spinosad
What is the most important information I should know about Comfortis: Comfortis is a prescription medication FDA approved for use in dogs and puppies 14 weeks of age or older to kill fleas and prevent flea infestations for one month. Comfortis is available in a Pink box for dogs 5 to 10 lbs (140mg), Orange box for dogs 10.1 to 20 lbs (270mg), Green box for dogs 20.1 to 40 lbs (560mg), Blue box for dogs 40.1 to 60 lbs (810mg), and Brown box for dogs 60.1 to 120 lbs (1620mg).
What is Comfortis: Comfortis is a chewable, synthetic beef flavored tablet (derived from pork protein and hydrolyzed soy) that is given to the dog to kill fleas and prevent flea infestations for one month. Comfortis chewable tablets are for monthly use in dogs and puppies 14 weeks of age and older.
What should I discuss with my veterinarian before giving Comfortis to my pet: Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog has a history of seizures (epilepsy).
How should this medication be given: Give Comfortis chewable tablets with food. Give Comfortis chewable tablets once a month. Comfortis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose the pet with another full dose. Store Comfortis at room temperature (68-77° F)
What happens if I miss a dose: Give the missed dose with food as soon as you remember and resume a monthly dosing schedule.
What happens if I overdose the pet: Overdose of this medication is unlikely. However, if an overdose is suspected, contact your veterinarian or veterinary emergency room. Symptoms of overdose that may occur include vomiting.
What should I avoid while giving Comfortis: Your pet may maintain normal activities and interactions while being given Comfortis. The safe use of Comfortis chewable tablets in male dogs intended for breeding has not been established.
What are the possible side effects of Comfortis: Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Comfortis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to the pet.
What other drugs will affect Comfortis: Talk to your veterinarian before giving any prescription or over the counter medications.
Where can I get more information: Your pharmacist has additional information about Comfortis written for health professionals that you may read.
Directions:
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Comfortis is a prescription medication used in dogs to kill fleas and prevent flea infestations for 1 month.
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Comfortis is not for cats.
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Comfortis chewable tablets are synthetic beef flavored.
Tip: If vomiting occurs within 1 hour of administration, redose the pet with another tablet.
Dosage:
Pet
Weight
Dosage
Dogs/Puppies: (14 weeks of age or older)
5-10 lbs (Pink Box)
Give one 140mg chewable tablet by mouth once a month with food. Comfortis may be chewed, offered in food, or administered like other tablet medications
10.1-20 lbs (Orange Box)
Give one 270mg chewable tablet by mouth once a month with food. Comfortis may be chewed, offered in food, or administered like other tablet medications
20.1-40 lbs (Green Box)
Give one 560mg chewable tablet by mouth once a month with food. Comfortis may be chewed, offered in food, or administered like other tablet medications
40.1-60 lbs (Blue Box)
Give one 810mg chewable tablet by mouth once a month with food. Comfortis may be chewed, offered in food, or administered like other tablet medications
60.1-120 lbs (Brown Box)
Give one 1620mg chewable tablet by mouth once a month with food. Comfortis may be chewed, offered in food, or administered like other tablet medications
Over 120 lbs
Give the appropriate combination of tablets
Cats:
Horses:
Storage: Store Comfortis at room temperature (68°-77° F).
I have used Comfortis on my dog "Lucky" for over 2 years now and found that by using it, he was so much more relieved & healthier. He never scratched, itched, or kept biting on himself. I would "highly" recommend Comfortis to any dog owner as this is the BEST. I have just recently run out and found Lucky Dog right back at the root of his problem. So, without his Comfortis, he suffers. He needs his once a month daily dose in order to maintain his flea problem, plus bring his relief.
We tried many different over the counter flea products for our Cocker Spaniel, but he kept being infested. Finally we asked the vet for an effective medicine. She recommended Comfortis. Within a week our dog was flea free! An added perk was we didn't have to chemically treat our home. I would strongly recommend this med for complete flea control. Just make sure to treat monthly.
I have tried everything and to date absolutely nothing works like Comfortis. I have an 8 yr. old Scottish Terrier, a 15 year old Doxie and a 5 month old Malti-poo. Flea problem, oh yeah. Get rid of them on one and next thing you know, the fleas are back. Now that all are on Comfortis, no fleas. Whoopee! Love the stuff.
This is truly a great product. I'm concerned about the owners giving this to their dogs that have a seizures. The precautions make it clear that it should not be given to dogs with a history of seizures. If your dog has any seizure history be careful. Vets should advise their clients.
Finally we found something that actually kills the fleas!!! Frontline caused seizures like most all of the topicals. Within an hour or so our dogs were itch free and were feeling so much better. i will continue to purchase Comfortis for my babies, no matter what the cost. Thank you 1800petmeds and Comfortis for loving my babies!!
Comfortis is a chewable tablet given every month to kill fleas and prevent flea infestations. Heartgard is given every month to prevent heartworms. While there can be an issue with using Comfortis at the same time as using high, extra-label doses of ivermectin, there should be no issue with using Comfortis and Heartgard together at the recommended monthly dose based on the pet's weight.
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.
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