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Chlorpheniramine 4 Mg Tabs

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Chlorpheniramine 4 mg Tabs 100 ct
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Product Info
How to Use
Customer Reviews
Product Info
What is Chlorpheniramine 4mg?

Chlorpheniramine is an antihistamine meant to be used for the temporary relief of allergy symptoms in pets.


Cats and Dogs

  • Begins to work within 1 hour
How it Works:

This medication works to remedy contact, inhaled, or drug-induced allergies in dogs and cats by blocking the effects of histamine in the body.


While in 4mg strength it's over-the-counter, there are possible negative interactions with other medications. Consult with your veterinarian. Side effects may include drowsiness, vomiting, diarrhea, lack of appetite, dry mouth, and urinary retention. Do not store in the bathroom, as it's sensitive to moisture.

Brand Name:

Chlor-Trimeton (Schering-Plough)

Generic Name:




What is this medication used for:

Chlorpheniramine is an antihistamine used in the treatment of contact, inhaled or drug-induced allergies in dogs and cats. It is also used to treat miliary dermatitis in cats.


Chlorpheniramine is available as tablets; long-acting capsules and tablets; and syrup.

How this medicine should be used:

Chlorpheniramine is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice to use this medication in dogs and cats. The usual dose for dogs is 2-8mg every 8-12 hours. For cats the usual dose is 1-2mg every 8-12 hours. Do not open or crush the long-acting capsules.

What are the side effects:

Side effects may include drowsiness, vomiting, diarrhea, and lack of appetite. Dry mouth and urinary retention can also occur.

What special precautions are there:

This medication should not be used in animals allergic to chlorpheniramine or similar antihistamines. Do not use chlorpheniramine when it is in combination with other medications such as acetaminophen or caffeine such as found in various cold and sinus products. Do not use in pregnant or lactating animals. Do not use in patients with glaucoma, prostate disease or urinary obstruction, stomach or intestinal obstruction, high blood pressure or hyperthyroidism. Use caution when given with phenothiazines such as acepromazine and other central nervous system (CNS) depressant medications. Chlorpheniramine should not be used with monoamine oxidase inhibitors (MAOIs) such as selegiline and Preventic tick collar. Use caution when given with metoclopramide. Always tell your veterinarian and pharmacist what other medications your pet is taking.

In the event of an overdose:

Contact your veterinarian or veterinary emergency room. Symptoms of overdose may include excitement or seizure, drowsiness, coma, respiratory depression and death.

How should I store this medication:

Keep this medication in the container it came in, tightly closed. Store at room temperature, away from excess heat, light, and moisture. Do not store in the bathroom. Throw away any medication that is outdated or no longer needed. Keep out of the reach of children and pets.

How to Use
  • Chlorpheniramine 4mg tablets are an over-the-counter (OTC) product.
  • Chlorpheniramine 4mg tablets are an antihistamine used to treat allergies.

Chlorpheniramine can interact with other medications. Check with your pharmacist or veterinarian before giving this medication to pets taking other medications.

All weights
1/2 - 2 tablets every 8-12 hours
All weights
1/4 - 1/2 tablet every 8-12 hours
Do not use!

Should be stored at room temperature.

Active Ingredient (per tablet)
Chlorpheniramine maleate
4 mg
Other Ingredients: (per tablet) D&C Yellow #10, lactose, magnesium stearate, microcrystalline cellulose, pregelatinized starch.
Customer Reviews
Chlorpheniramine 4 Mg Tabs is rated 4.0 out of 5 by 88.
Rated 1 out of 5 by from WARNING! DO NOT BUY! The vet recommended this for my cat because of his sneezing and some coughing and she thought he had allergies. I gave the dose the vet recommended to him every day for three weeks. I stopped when I noticed his excessive scratching, clumps of fur on the floor and his now lethargic behavior. Before this product ALL my cat had was sneezing and coughing and NOW he is lethargic with a skin condition. Now it’s back to the vet in the hopes we can fix his scratching problem.
Date published: 2016-02-13
Rated 5 out of 5 by from Really helped my cat! I have a Sphynx cat who has been extremely itchy since day one. I found that just half a pill a day does wonders for him! He is no longer all scratched up and miserable.
Date published: 2016-02-01
Rated 5 out of 5 by from Gabrielle is a rescue and came with allergies galore! Not to sound gross but snot would go everywhere when she sneezed which was way to often. She is an older cat with very persnickety tastes... she doesn't know she is taking this medication. I crush it up and put it in her wet food at night... 1/2 a pill. What a difference! Amazing! Thank you!
Date published: 2016-01-30
Rated 5 out of 5 by from Worked for me Roxy our cat was scratching and pulling her hair out. Tried Benadryl, taste was bad but it did work but if pill didn't go right down she would foam at the mouth. So I tried this product which seems to work. I only give her half pill in morning and half at night with feeding. I crush and mix with wet food and she seems to take it no problem. I also added more fish to her diet which also seems to help with some dry skin. Overall very happy with results and hair is starting to grow back.
Date published: 2015-06-12
Rated 4 out of 5 by from Less sneezing My pug's nose is always running. One dose in the morning when the dripping is worst does the trick for four hours.
Date published: 2015-04-03
Rated 3 out of 5 by from Not Great My poor white boxer scratches so much. He has skin allergies and was getting prednisone shots from his vet and they did help for a little while. I wanted to try something else and thought this may help, but its just like benadryl. I guess he will be going back to the vet for something else.
Date published: 2014-11-30
Rated 3 out of 5 by from worried about giving it I bought this in the cat category... ...And got a free dog bone. Thanks for the gift but it was useless. This company should ask what type of pet it is before sending free items. My cat had been sneezing a lot (so was I) and I was going to give him this to help. There were dosage directions on this site so I ordered. Shipping was pretty quick and item was well packaged. I read the bottle and was a bit concerned when the label (directions for people) mentioned not to give it to children under age 6. Even over age 6, they recommended 1/2 a tablet. How can I feel comfortable giving that to a cat that's a bit over 1 year old. Fortunately, his symptoms went away so I did not use it. Any feedback on this?
Date published: 2014-06-19
Rated 5 out of 5 by from Excellent medicine. Poor Jerry (cat) was having an allergic problem for a long time, I took him to the vet, who said he was perfectly fine and that everything was just a grooming thing!!! Paid $75.00 to hear that. One of my daughters has a cat with the same problem and she told me the vet has given her cat an antihistaminic medicine that I thought my vet was going to suggest, at least, that for my cat. But nothing. For a long time I was thinking how to get the medicine without a prescription and voila, found it at Pet-Meds. Beautiful Jerry is now doing way better than weeks before, hardly any scratching and so far, I don't see any big side effect; I just see him calmer and happier without that constant scratching he was under for months (day & night). The only cons I see it that the pill is a bit too big and therefore not easy to put iin one pill pocket, I have to use at least 2 of them or give him only half of the pill which has been working good, too. Very happy with the results !!
Date published: 2014-06-09
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Can I crush this pill and mix it with water to use a syringe to get my cat to take it?

My cat is having a hard time taking pills. He fights so hard against taking it, it turns into a very stressful situation. I'd like to crush it up. mix it with water and syringe shoot it into his mouth. Is there any issues with getting it into him this way? He is an 18lb cat and the vet said to take an entire 4mg pill.
Asked by: Jenn
I got this from my veterinarian. They gave me a pill shooter. You put it inbetween their side teeth and the pill lands on the back of the tongue. It takes seconds and your cat won't know what happened. 
Answered by: Junet
Date published: 2016-05-01

Alermine 4mg

I have a Pomerian and she has had a bad cough I found some pills but not sure what they are I want to check before I give them to her. It's Alermine 4mg I want to make sure these are what I need to give her. they have a pyramin and 016 on them and yellow in color is this just a different pharmacy brand or something else.
Asked by: Chizzy
Please contact your local Poison Information Center to help identify the tablet in your possession.
Answered by: Lilli Pharmacist
Date published: 2014-10-27

How soon will side effects show?

I have a mini dachshund with allergies. I have been giving her .25 of a tablet twice a day for the past 5 days. She has vomited twice today and was wondering if this could be a side effect of the medicine. Could she begin to have side effects on her 5th day of taking the medication?
Asked by: Andrea
Side effects are usually seen sooner; however, it may be possible. Consult your veterinarian to rule out other causes.
Answered by: Lisa M
Date published: 2015-05-14

what is identifying number on pill

Asked by: Boo
Thank you for your question. The identifying number is 44 194.
Answered by: Maureen PetMeds Pro
Date published: 2014-06-29

Is chlorpheniramine safe to use with trifexis

Asked by: Daisy
Answered by: Linda M 1800petmeds pharmacist
Date published: 2014-01-18

how long can a dog stay on chlorpheniramine.?

Asked by: Anonymous
Before continuing medication you should see your vet first and have him evaluated before using long term. Long term use is not recommended without your vets consultation.
Answered by: James PetMeds Pro
Date published: 2015-05-28

atopy allergies in dogs

is it safe to use allergy meds while treating with frontline?
Asked by: Zoey
I use other flea control products and allergy meds because one is external and the other internal. The Frontline is topical and this is internal so shouldn't hurt. The combination was recommended to me by my veterinarian. I also use Hydrocortisone spray for allergy flare ups as recommended by my vet.
Answered by: Milosauburnam
Date published: 2013-09-29

Can you give your dog Chlorpheniramine HCL if they also use Comfortis for Flea control and Heartgard for Heartworms?

Asked by: Sarah N
Yes, you may give chlorpheniramine with Comfortis as there are no known drug interactions.
Answered by: Janine M./Pharmacist
Date published: 2013-09-20
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