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Topical Spray 120 ml
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Product Info
How to Use
Customer Reviews
Product Info
What is Betagen?

Betagen is a topical spray used on dogs for the treatment of infected superficial lesions caused by bacteria. It contains gentamicin, an antibiotic, and betamethasone, an anti-inflammatory. Betagen requires a prescription from your veterinarian.



  • Great for hot spots, rashes
  • Can speed up healing of skin infections
  • Effective treatment for dogs with sensitive skin and allergies
  • Customers rave about how easy it is to use
How it Works:

Betagen is a combination of an antibiotic to treat bacterial infections and a corticosteroid to treat any accompanying inflammation or itching.


Betagen should not be used for than 7 days unless otherwise directed by your veterinarian. Do not use if your pet has a viral or fungal infection. Tell your veterinarian if your pet is pregnant or lactating.

Brand Name:

Betagen Topical Spray (Med-Pharmex)

Generic Name:

Gentamicin Sulfate with Betamethasone Valerate Topical Spray (jen-ta-my'-sin, beta-meth'-a-zone)

What is the most important information I should know about Betagen Topical Spray:

Betagen Topical Spray is a prescription medicine FDA approved for veterinary use in dogs. Betagen Topical Spray is available in a 120 ml plastic spray bottle. Each ml contains gentamicin sulfate equivalent to 0.57mg gentamicin base and betamethasone valerate equivalent to 0.284mg betamethasone.

What is Betagen Topical Spray:

Betagen Topical Spray is an antimicrobial and corticosteroid combination used on dogs for the treatment of superficial lesions caused by susceptible bacteria. Betagen Topical Spray may also be used for purposes other than those listed.

What should I discuss with my veterinarian before using Betagen Topical Spray on my pet:

Do not use Betagen Topical Spray if the pet has a viral or fungal infection. Tell your veterinarian if your pet is pregnant or lactating.

How should this medication be used:

Use this medication exactly as directed by your veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. The usual dose for dogs is 2 sprays administered 2-4 times a day for 7 days. Hold the spray bottle upright and 3-6 inches from the affected area. Store Betagen Topical Spray at room temperature, away from moisture and heat. Keep out of the reach of children or pets.

What happens if I miss applying a dose:

Apply the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not give a double dose of the medication.

What happens if I overdose the pet:

An overdose of this medication is unlikely. If an overdose is suspected, seek emergency veterinary medical treatment.

What should I avoid while using Betagen Topical Spray on my pet:

Do not use this medication in pets allergic to it or any of the individual ingredients. Treatment beyond 7 days may lead to prolonged wound healing.

What are the possible side effects of Betagen Topical Spray:

Serious side effects are not expected. Prolonged use of this medication may give rise to the overgrowth of nonsusceptible organisms such as fungi and yeasts. Weight loss, increased thirst and urination, vomiting and diarrhea have occurred in animals following the use of synthetic corticosteroids. Continue the medication and talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.

What other drugs will affect Betagen Topical Spray:

Before using Betagen Topical Spray, tell your veterinarian if your pet is using other antibiotic or corticosteroid medications either topically or by mouth. Talk to the veterinarian or pharmacist before giving any prescription or over the counter medicines.

Where can I get more information:

Your pharmacist has additional information about Betagen Topical Spray written for health professionals that you may read.

How to Use
  • Betagen Topical Spray is an antimicrobial and corticosteroid combination available by prescription used on dogs for the treatment of superficial lesions cause by susceptible bacteria.
  • Treatment beyond 7 days may result in prolonged wound healing.
  • Prior to treatment, remove excessive hair and clean the lesion and adjacent area.
  • Betagen Topical Spray is for topical use on dogs only.

Do not use Betagen Topical Spray if your pet has a viral or fungal infection.

All weights
Hold the spray bottle upright and 3-6 inches away from the affected area. The usual dose for dogs is 2 sprays administered 2-4 times a day for 7 days.
Do not use!
Do not use!

Store this product at room temperature, away from moisture and heat.

Betagen Topical Spray:
Active Ingredients (per ml)
Gentamicin Sulfate
0.57 mg
Betamethasone Valerate
0.284 mg
Isopropyl Alcohol
163 mg
Propylene Glycol
Methylparaben (a preservative)
Propylparaben (a preservative)
Purified Water
* Hydrochloric acid may be added to adjust pH.
Customer Reviews
Betagen is rated 4.7 out of 5 by 34.
Rated 5 out of 5 by from Very effective for dogs with allergy breakouts This topical spray has helped heal my dogs' allergy breakouts. It is easy to use and if effective right away. Great for "hot spots"
Date published: 2016-01-03
Rated 5 out of 5 by from Betagen Bacterial Topical Spray I use the Betagen Bacterial Topical Spray on my 12 YAO Doxie who had developed numerous skin infections. His vet was issuing antibiotics in a tablet form when this started which cleared the skin infections, but within a short amount of time the infections returned. The vet then suggested trying a bacterial spray which I purchased from the vets office. This appeared to correct the skin infection also. When the skin infection returned the vet didn't like the idea of another issue of antibiotic tablets as the vet was worried that my Doxies Immune System might build up a tolerance to them, so it was suggested that the topical spray should be tried due to the fact it's external vice internal. Within two weeks of twice a day dosage the skin infection has totally cleared. Also it appears that for some unknown reason my Doxies Immune System has problems fighting off external infections, the Batagen Bacterial Topical Spray has corrected this problem for the time being.
Date published: 2015-05-30
Rated 2 out of 5 by from Im sure this product would work on the right skin irritation but for my Golden I bathed her and put the Betagen daily 1wk and ran out she is 131 lbs ordered another bottle this time a120ml and she seems to have new sores since then. Help! Vet said could be low Thyroid, test came out ok not low enough for oral meds, and not safe for oral antibiotics not he said. also shampooing with Melaseb
Date published: 2014-09-15
Rated 5 out of 5 by from Boston-Pug (Bug) My boy had a cone put around his head since his lesion needed healing after scratching it to oozing blood. After his finished powder to stop the bleeding and antibiotic, we sprayed this on him twice daily. A few days later we already see VAST improvement! Thank you, Betagen for saving our pup's life!
Date published: 2014-08-04
Rated 5 out of 5 by from Works awesome on hot spots! Love this stuff
Date published: 2014-06-21
Rated 4 out of 5 by from Great product! My dog suffers from allegies and Betagen gives my dog on contact relief. My vet prescribed a smaller bottle so I was pleased that PetMed offers a bottle with more ounces.
Date published: 2014-01-18
Rated 5 out of 5 by from Awsome Healing This Product is from heaven, it heals in min. the sensitive Skin, Foot allergies, all kind of irritation. Thank you!! and 1-800-PetMets is always very helpful to, because the vets are stubborn.
Date published: 2013-12-23
Rated 5 out of 5 by from Best product we have used Our 7 year old Cairn has been miserable with allergies for the last 6 years. 4 to 5 vet trips a year and hundreds of $$$'s on shots, pills and salves and she was getting no better. Plus I hated giving her steroids. Tried Betagen and voila a miracle!!! All redness and soreness is gone within 2 days. I check her every day and don't hesitate to give her a spritz whenever I discover a red area. I believe in this product completely.
Date published: 2013-09-12
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Is there a shelf life, expiration date on this product ?

Asked by: S Wolf
Yes, there is an expiration date for Betagen. It varies based on when the product was manufactured, and should be on the bottle.
Answered by: Christine
Date published: 2016-10-18

Can it be used in cats also ?

Asked by: Kitty
Currently, betagen is only FDA approved for use in dogs. Speak with your cats vet before using betagen on it.
Answered by: Christine
Date published: 2016-09-28

can this be used on cats?

Asked by: Anonymous
Hi there, this medication is for dogs only.
Answered by: James PetMeds Pro
Date published: 2015-10-03

IS there something close to Betagen available over the counter?

We've used Betagen successfully before on our Airedale's Hot Spots. He just got another one, we only have one does left and the Vet won't write a prescription without seeing him The soonest they can do that is 5 days from now. Is there something available over the counter that might work?
Asked by: Anonymous
There are some over-the-counter products such as Excel Hydrocortisone Spray With Aloe Vera and Be Soothed. Tea Tree Oil Skin Relief that may provide temporary relief of itching from minor skin irritation, inflammation, insect bites and seborrheic dermatitis. However speak to your veterinarian to determine if these are appropriate. Your pet should be seen to determine your pet should be treated for an infection.
Answered by: Anonymous
Date published: 2014-09-05

Can this be used around the genital area?

Asked by: Anonymous
It depends. A veterinarian would have to determine if its the best choice based on an examination The veterinarian may determine that a cream or ointment may be more gentle for that area.
Answered by: Linda petmeds pharmacist
Date published: 2014-07-30

Does it work on fatty lumps found on the skin of my lab?

My lab is about 6 years old and developed a red lump on his belly. I took him to see the vet and they tested and told me its nothing to be concerned of and it could just be fatty skin that is normal for labs. He said to just watch out for it to see if it grows. Its been bout two months now and it may have grown a little if not at all. I wanted to find a skin medication that could reduce the size and possible remove the lump. Could someone recommend the best option for me? Thank you!
Asked by: Anonymous
This medication is indicated for superficial bacterial infections of the skin. Consult with your veterinarian of appropriate options for your pet.
Answered by: Anonymous
Date published: 2014-06-13

can I use betagen on my dogs paw, small puncture from other dog bite

Asked by: Anonymous
I personnel would use a healing cream also what has a antiseptic purpose.
Answered by: Anonymous
Date published: 2015-03-09

cortizon spray

my vet gave this to me for my cats bad reaction to some sort of insect bite. Inside cat no fleas. It was healing but after 3 days, he scratched it raw again. Can I use cortisone with this?
Asked by: Anonymous
it is not advised on an open wound unless your vet determines that it is safe to use. Please check with your vet......He may instruct you to clean the area first and may want you to use something without a steroid in it.
Answered by: Linda petmeds pharmacist
Date published: 2013-12-04
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