Heartgard Plus Chewables - Simparica TRIO - Trifexis
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Heartgard Plus Chewables
Simparica TRIO
Prevents Heartworm Disease checkmark checkmark checkmark
Roundworms X mark checkmark X mark
Hookworms checkmark checkmark checkmark
Whipworms X mark X mark checkmark
Tapeworms X mark X mark X mark
Fleas X mark checkmark checkmark
Other Parasites X mark Protects against 5 types of ticks X mark
Safe for Breeding, Pregnant or Nursing Pets Has shown a wide margin of safety at the recommended dose level in dogs, including pregnant or breeding bitches, stud dogs and puppies aged 6 or more weeks. The safe use of Simparica TRIO has not been evaluated in breeding, pregnant, or lactating dogs. Consult your veterinarian about the use in breeding females. The safe use in male dogs intended for breeding has not yet been evaluated.
Age/Weight Requirements 6 weeks of age or older and no weight requirement 8 weeks of age or older, weighing 2.8 lbs or more 8 weeks of age and older and weighing at least 5 lbs
Rx Prescription Required checkmark checkmark checkmark
Dosage Monthly
Usage Heartgard Plus Chewables Usage Simparica TRIO Usage Trifexis Usage
Video Video coming soon Video coming soon Video coming soon
Veterinarian Review (Michael Dym, VMD) In my experience and opinion, the main ingredient ivermectin in this once monthly heartworm preventative is the most effective preventative for canine heartworm. Under veterinary supervision, it can even be an alternative TREATMENT in treating active heartworm infections when used monthly in those dogs who are either too old for the expensive conventional immiticide drug treatment, or where risks of immiticide treatment outweigh the benefits. This should be discussed with your pets veterinarian. Pets can often clear heartworm infection after 12-24 months of consecutive use, again best done under veterinary guidance. With its other main ingredient, pyrantel, heartguard plus is the most effective preventative in controlling/treating/preventing roundworm and hookworm infection in dogs. Dogs also seem to prefer the taste of this beef flavored chewable tablet. The main disadvantage is of this product is in those situations where pets have tested positive for whipworms on stool checks. This preventative does NOT prevent or control whipworm infections, which can cause inflammation of the colon/diarrhea, and be difficult to control in affected dogs. Coming soon Currently under review
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.

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