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Comfortis - Credelio
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Comfortis
Credelio
Kills Fleas checkmark checkmark
Repels Fleas X mark X mark
Kills Flea eggs and Larvae X mark N/A
Kills Ticks X mark checkmark
Repels Ticks X mark X mark
Kills and/or Repels Mosquitoes X mark X mark
Prevents Heartworm X mark X mark
Other Parasites Information X mark N/A
Waterproof (shampooing once a week can reduce effectiveness) N/A N/A
Safe for pregnant or nursing Pets Consult your veterinarian The safe use of Credelio in breeding, pregnant or lactating dogs hasn't been evaluated.
How long does it take to work Kills fleas within 30 minutes. Credelio starts killing fleas within 4 hours of administration and kills over 99% of fleas within 8 hours of administration.
Taste Beef Flavor Beef-flavored chewable
Active Ingredient(s) Spinosad Lotilaner
RX Required checkmark checkmark
Dosage
Usage Comfortis Usage Credelio Usage
Video
Vet Review I have started to use this product over the past several months and have mixed feelings about it. A big advantage is the ease of administering the beef and pork flavored tablet but it should be administered on full stomach. And while it avoids the oily liquid pesticides on the back that many clients don ' t like, if a pet is allergic to beef or pork this is a big disadvantage. The best thing about this product (which is similar to Capstar) is the quick kill of adult fleas working within 30 minutes and being almost 100 percent effective against fleas within 4 hours of giving it, and lasting for a month!!! (much longer than a Capstar pill.) A big problem is not only the expense but it also has no tick coverage. In my experience and opinion, I have also seen several dogs vomit when given this pill and it is really not supposed to be used in patients with seizure disorders, which is also a concern of mine in terms of safety. Along the same line, it is not supposed to be used in pregnant or nursing females, as from what I understand when the product was tested there were supposed loss of litter during pregnancy, poor weight gain of puppies and vomiting, the latter symptom which I have seen in clinical practice. In general I am always a little worried about products not approved for young puppies, as the puppies have to be at least 14 weeks of old, according to the label use of this product. It is not a cheap product, and for the above reasons I don't use it often even though it is tremendously effective against fleas. For the reasons stated above, I therefore give this product an overall rating of 2 with effectiveness (for fleas) of 4, the ease of use a 5, and the taste a 4. I still prefer Front line, Advantage and K9 Advantix despite the oily spot because of the increased coverage of parasites, and my concerns about safety Belonging to the latest generation of flea/tick parasiticides(known as Isoxazoline medications), these palatable, beef flavored chewable tablets kills fleas quite effective, with most adult fleas being killed within 8 hours. One of the downsides, as compared with Vectra 3D is that Credilio does not repel either fleas or ticks, and has no effect on biting mosquitoes, which are the main vectors that transmit heartworms to dogs. Credilio and products of its class are one of the most effective products against several species of severe disease transmitting ticks, including ones that transmit Lyme Disease, Ehrlichiosis, Rocky Mountain Spotted Fever and Anaplasmosis, which have been increasing in incidence in recent years. As with other members of this drug class, we have also used this drug in treatment and prevention of both demedex mites and scabies mites, although this is an off label use. Giving with a full meal reduces risks of digestive reaction. Overall the tablet is well tolorated, but occasional diarrhea, vomiting or digestive upset is seen. I would look to one of the other products like Vectra 3D, if there is a history of significant neurologic disease or seizures. I give this product an overall rating of a 4 out of 5.
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.

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