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Advantage II - Frontline Plus - Vectra for Cats
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Advantage II
Frontline Plus
Vectra for Cats
Kills Fleas checkmark checkmark checkmark
Repels Fleas X mark X mark X mark
Kills Flea eggs and Larvae checkmark checkmark checkmark
Kills Ticks X mark checkmark X mark
Repels Ticks X mark X mark X mark
Kills and/or Repels Mosquitoes X mark checkmark X mark
Prevents Heartworm X mark X mark X mark
Other Parasites Information Treats, Prevents, and Controls Lice Infestations Eliminates infestations with chewing lice, aids in the control of sarcoptic mange infestation N/A
Waterproof (shampooing once a week can reduce effectiveness) checkmark checkmark checkmark
Safe for pregnant or nursing Pets Consult your veterinarian checkmark X mark
How long does it take to work Kills fleas in 12 hours Kills Fleas within 12 hours and Ticks within 48 hours Kills fleas withing 6 hours
Taste Applied to Skin Applied to Skin N/A
Active Ingredient(s) Imidacloprid/Pyriproxyfen Fipronil/(S)-Methoprene dinotefuran, pyriproxyfen
RX Required X mark X mark X mark
Dosage
Usage Advantage II Usage Frontline Plus Usage Vectra for Cats Usage
Video /images/products/video/petmeds-flea-preventative-advantage.flv /images/products/video/petmeds-flea-preventative-frontline-plus.flv Coming soon
Vet Review The non-greasy, non-odor formulation is a definite plus when used on sensitive patients, especially cats. I find that advantage kills fleas and larvae more quickly than some of the other products out there,  often resulting in quicker relief of flea allergy dermatitis symptoms in dogs and cats. Overall I have found it quite safe and have seen the fewest topical or rare systemic reactions in my practice over the years.  The main disadvantage I have found is that in heavy flea infestations that the efficacy may wear off in less than one month, necessitating some vets to recommend more frequent off label use of this product every few weeks.  It also does not control ticks as well on dogs and cats.  I find that advantage works most effectively when combined with good environmental flea control at home. I find that the effective combination of an ingredient like fipronil, along with the insect growth regulator methoprene, provides the best spectrum of activity and protection against all stages of the flea life cycle from egg through larval stage on to adult. Because of these two main ingredients and their method of action, I find that clients don't have to treat the environment as much. I find that this product tends to be safer in smaller breed animals when compared to its competition. I find its tick efficacy quite good. The fact that it is waterproof also allows clients, whose pets swim frequently, to confidently use this product during the swimming months. I also find that this product works the longest for fleas, while some of the competitive products have to be reapplied before the end of the month. The lack of label efficacy against mosquitoes and flies, as well as the fact that this product does not repel fleas or ticks are the two main disadvantages. As with any insecticidal products, I find that every pet is an individual, in terms of which of the products works best on them. When I am dealing with more of a flea issue in a patient, this is the product I will likely reach for first. Coming soon
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.

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