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Bravecto Chews - Credelio - Trifexis
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Bravecto Chews
Credelio
Trifexis
Kills Fleas checkmark checkmark checkmark
Repels Fleas X mark X mark X mark
Kills Flea eggs and Larvae Bravecto also kills newly emerged fleas before they can lay eggs. N/A checkmark
Kills Ticks checkmark checkmark X mark
Repels Ticks X mark X mark X mark
Kills and/or Repels Mosquitoes X mark X mark X mark
Prevents Heartworm X mark X mark checkmark
Other Parasites Information X mark N/A Treats and controls hookworms, roundworms, and whipworms infections.
Waterproof (shampooing once a week can reduce effectiveness) N/A N/A N/A
Safe for pregnant or nursing Pets Safe for use in breeding, pregnant, and lactating dogs. The safe use of Credelio in breeding, pregnant or lactating dogs hasn't been evaluated. Consult your veterinarian
How long does it take to work Starts to kill fleas in 2 hours. Credelio starts killing fleas within 4 hours of administration and kills over 99% of fleas within 8 hours of administration. Starts to kill fleas within 30 minutes; kills 100% of fleas within 4 hours.
Taste Tasty Chew Beef-flavored chewable Beef Flavor
Active Ingredient(s) Fluralaner Lotilaner Spinosad/Milbemycin Oxime
RX Required checkmark checkmark checkmark
Dosage
Usage Bravecto Chews Usage Credelio Usage Trifexis Usage
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Vet Review An exciting new development in the fight against fleas and ticks is the long lasting chewable tablet called Bravecto, The active ingredient fluralaner, is a very effective ectoparasiticide, which acts on the nervous system of the parasite, without affecting the dog's nervous system. When given to dogs, this product starts killing fleas within 2 hours, and ticks a short time after that. Protection will last for approximately 12 weeks for fleas, and 8-12 weeks for ticks. In fact, clinical experience has shown it to be effective in treating and controlling 4 species of ticks, many of which are involved in transmitting disease to both dogs and people. It is even safe to use in pregnant and lactating animals, as well as most pets over the age of 6 months. I would use caution in using this or any other pesticide in sick, geriatric or pets with chronic immune mediated disease. Another minor drawback is that the fleas or tick must be ingesting a blood meal or feeding on your pet before becoming effective, thus there is still a remote possibility of transfer of certain tick born illnesses on rare occasion. Unlike most topical products that can potentially be washed or bathed off, the added benefit of giving a pill minimizes pesticide exposure for human family members, as well as being effective within a very short period of time. I give this product an overall rating of a 5 with an ease of use, and efficacy a 5 as well. Belonging to the latest generation of flea/tick parasiticides(known as Isoxazoline medications), these palatable, beef flavored chewable tablets kills fleas quite effective, with most adult fleas being killed within 8 hours. One of the downsides, as compared with Vectra 3D is that Credilio does not repel either fleas or ticks, and has no effect on biting mosquitoes, which are the main vectors that transmit heartworms to dogs. Credilio and products of its class are one of the most effective products against several species of severe disease transmitting ticks, including ones that transmit Lyme Disease, Ehrlichiosis, Rocky Mountain Spotted Fever and Anaplasmosis, which have been increasing in incidence in recent years. As with other members of this drug class, we have also used this drug in treatment and prevention of both demedex mites and scabies mites, although this is an off label use. Giving with a full meal reduces risks of digestive reaction. Overall the tablet is well tolorated, but occasional diarrhea, vomiting or digestive upset is seen. I would look to one of the other products like Vectra 3D, if there is a history of significant neurologic disease or seizures. I give this product an overall rating of a 4 out of 5. An exciting and brand new product now available combines the main ingredient of Interceptor milbemycin with a powerful flea insecticide known as spinosad.  Given as a once monthly heartworm preventative, this product also will control and prevent whipworms, hookworms and roundworms, in addition to preventing heartworms. The additional ingredient spinosad allows effective flea and these internal parasite control all in one pill,  making it quite convenient for clients.  As with any pesticide rare digestive tract and neurological side effects may occur but this has not been a major problem in clinical trials. Since it is relatively new I will have to see how this product performs on the fleas but it seems to have excellent potential. I give this product an overall rating of a 5 with an ease of administration a 5 as well, taste a 5.
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.

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