What is Proin ER?

Proin ER is a safe and effective FDA-approved once-a-day tablet that controls urinary incontinence in dogs due to urethral sphincter hypotonus. It works by increasing urethral sphincter tone to help prevent urinary accidents. It's easy to administer. The liver-flavored tablets are given with food in a single dose per day. The patented release technology provides controlled release that ensures steady absorption. Proin ER provides the same proven efficacy as Proin in extended-release tablets. Proin ER requires a prescription from your veterinarian.

For:

Dogs

Benefits:

• Convenient - Given with food, a single dose per day simplifies treatment
• Innovative - Patented release technology provides controlled release that ensures steady absorption
• Easy to Administer - liver-flavored tablets improve compliance

How does Proin ER work?

Proin ER works by increasing urethral sphincter muscle tone to help prevent urinary leakage.

Cautions:

Not for human use. Keep out of reach of children. Consult a physician in case of accidental ingestion by humans. Keep Proin ER in a secured location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Proin ER may mask signs of incontinence due to urinary tract infection. Proin ER is not effective in dogs with incontinence due to neurologic disease or malformations. Proin ER may cause hypertension; therefore, use with caution in dogs with pre-existing heart disease, hypertension, liver disease, kidney insufficiency, diabetes, glaucoma, and conditions with a predilection for hypertension. Proin ER may cause increased thirst; therefore, provide dogs with ample fresh water. The safe use of Proin ER has not been evaluated in dogs that are intended for breeding, or that are pregnant or lactating.

Brand Name:

Proin ER (Pharmacal)

Generic Name:

Phenylpropanolamine hydrochloride extended-release tablets

What is the most important thing I should know about Proin ER?

Proin ER is indicated for the control of urinary incontinence due to urethral sphincter hypotonus in dogs. It requires a prescription from your veterinarian. Proin ER provides the same proven efficacy as Proin in extended-release tablets. The patented extended-release technology provides a controlled release mechanism that achieves steady absorption.

What should I discuss with my veterinarian before giving Proin ER to my pet?

Let your vet know if your dog is pregnant or lactating, or if they are taking any other medications.

How should Proin ER be given?

Proin ER should be given once daily with food. Give Proin ER exactly as directed by your veterinarian. If you do not understand the directions, ask the pharmacist or veterinarian to explain them to you.

What are the potential side effects of Proin ER?

The most commonly reported side effects were vomiting, loss of appetite, diarrhea, excessive salivation, agitation, tiredness, vocalization, confusion, increased water consumption, weight loss, weakness, fever, panting, and reversible changes in skin color (flushing or bright pink). Abnormal gait, seizures or tremors, as well as liver enzyme elevations, kidney failure, blood in urine and urine retention have been reported. Contact your veterinarian if you notice restlessness, irritability, loss of appetite, the incontinence persists or worsens, or any other unusual signs. Proin ER may cause increased thirst; therefore, provide dogs with ample fresh water.

What happens if I miss giving a dose of Proin ER?

If you forget to give your dog a dose, give the missed dose as soon as you remember. If it is close to the next dose, skip the missed dose and resume dosing at the next scheduled dose.

What happens if I overdose my pet on Proin ER?

Contact your veterinarian immediately if your dog ingests more tablets than prescribed or if other pets ingest Proin ER.

What other drugs will affect Proin ER?

Use with caution in dogs receiving sympathomimetic drugs, tricyclic antidepressants, or monoamine oxidase inhibitors as increased toxicity may result. Use with caution in dogs administered halogenated gaseous anesthetics as this may increase the risk of cardiac arrhythmias.