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1-800-PetMeds EXCLUSIVEFlea5X Plus - Generic to Frontline Plus

Starts $39.35 $27.62 
Ships in one business day or less

Step 1. Select Pet's Weight:

Dog
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3 pack
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$34.52
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6 pack
$71.22
$62.48
$49.98
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12 pack
$135.34
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$94.98
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Starts $39.35 $27.62 
Ships in one business day or less

Step 1. Select Pet's Weight:

Dog
Cat

Step 2. Select a Supply:

3 pack
$39.35
$34.52
$27.62
Price w/coupon SAVE20
6 pack
$71.22
$62.48
$49.98
Price w/coupon SAVE20
Free Shipping
Save $5 over 3 pk
12 pack
$135.34
$118.72
$94.98
Price w/coupon SAVE20
Free Shipping
Save $15 over 3 pk

Step 3. Select a Quantity:

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Product Info

What is Flea5X Plus - Generic to Frontline Plus?

Flea5X Plus is a monthly topical flea and tick preventative for dogs and cats over 8 weeks of age. It contains the same active ingredients as Frontline Plus. Flea5X Plus contains fipronil to quickly kill adult fleas, ticks and chewing lice on your pet. Flea5X Plus also contains (S)-methoprene, an insect growth regulator that kills flea eggs and larvae to help end the flea life cycle. In addition to killing adult fleas and preventing reinfestation, Flea5X Plus is effective against ticks such as the brown dog tick, the American dog tick, the lone star tick and the deer tick, including those that may transmit Lyme disease. Choose Flea5X Plus for a great savings over leading comparable brands and get the same effective protection for your pet.

For:

Cats/Kittens over 1.5 lbs (8 weeks or older), Dogs/Puppies over 4 lbs (8 weeks or older)

Benefits:

  • Each application protects your pet from multiple pests for a full month
  • Helps control sarcoptic mange infections in dogs
  • Kills fleas that may cause skin allergies
  • Waterproof formula won't wash off during swimming or bathing
  • Kills fleas, flea eggs, flea larvae, ticks (including those that may transmit Lyme disease and other tickborne diseases), and chewing lice
  • Compare to Frontline Plus, containing the same active ingredients
  • Prevents and controls infestations for 30 days

How does Flea5X Plus work?

Flea5X Plus contains fipronil, a slow-acting, broad-spectrum insecticide that disrupts the central nervous system of fleas and ticks. It also contains (S)-Methoprene, an insect growth regulator that helps to stop the flea life cycle by killing flea eggs and larvae. The waterproof formula means your pet will be protected even after swimming or bathing.

Please note: This product is not manufactured or distributed by Merial, the makers of FRONTLINE® Plus. FRONTLINE® is a registered trademark of Merial.

Cautions:

Do not use Flea5X Plus for Dogs on cats. Do not use Flea5X Plus for Cats on dogs. Keep pets away from other treated pets for 24 hours. Contact your veterinarian immediately if Flea5X Plus for Dogs is applied to your cat or ingested by your cat, or if Flea5X Plus for Cats is applied to your dog or ingested by your dog. Your pet may experience some temporary irritation at the site of application. If signs persist or become more severe within a few days of application, consult your veterinarian immediately. Harmful if swallowed. Causes eye irritation. Avoid contact with skin, eyes, or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet. If swallowed, call a poison control center or a doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything by mouth to an unconscious person. If in eyes, flush eyes with plenty of water. Call a doctor if irritation persists. If on skin, wash with plenty of soap and water. Get medical attention if irritation persists.

Brand Name:

1-800-PetMeds Flea5X Plus

Generic Name:

fipronil & (S)-methoprene

What is the most important thing I should know about Flea5X Plus?

Flea5X Plus kills fleas, ticks, and chewing lice, and controls mites that may cause sarcoptic mange in dogs. It is a long-lasting, fast-acting and waterproof formula containing the same active ingredients as Frontline Plus. The active ingredients are Fipronil & (S)-methoprene. Flea5X Plus for Dogs is a non-prescription (OTC) product. Flea5X Plus for Cats is a non-prescription (OTC) product.

What should I discuss with my veterinarian before giving Flea5X Plus to my pet?

Consult your vet before using on debilitated, aged, or medicated pets. Also consult your vet before using on pregnant or nursing dogs. Flea5X Plus for Cats can be used on breeding, pregnant, or lactating cats. Consult a veterinarian before using on pets with known organ dysfunction. Pets may experience temporary irritation at application site.

How should Flea5X Plus be applied?

Use Flea5X Plus for Dogs on dogs and puppies weighing over 4 lbs and 8 weeks of age or older. Use Flea5X Plus for Cats on cats and kittens weighing over 1.5 lbs and 8 weeks of age or older. It is available as 0.50 ml applicators for cats, 0.67 ml applicators for dogs 4-22 lbs, 1.34 ml applicators for dogs 23-44 lbs, 2.68 ml applicators for dogs 45-88 lbs and 4.02 ml applicators for dogs 89-132 lbs. Wait 24 hours for product to dry before allowing your pet to go swimming or bathing your pet. Do not reapply for 30 days. To apply, remove tubes from packaging and separate one tube from the rest of the pack. Hold with the notched end pointing up and away from your face. Cut off the end at the notch along the lines. With one hand, spread the fur on your pet's back between the shoulder blades and invert the tube over your pet. Use the open end of the tube to part the fur completely and squeeze the tube firmly to apply all the contents onto that one spot. Wash hands after application.

What are the potential side effects of Flea5X Plus?

Pets may experience some temporary irritation at the site of product application. If signs persist, consult a veterinarian immediately. If signs of sensitivity occur, bathe your pet with soap and rinse with large amounts of water. If signs continue, contact your veterinarian immediately. Do not allow children to apply this product.

What happens if I miss giving a dose of Flea5X Plus?

Apply the dose as soon as you remember and resume a regular monthly schedule thereafter.

What happens if I overdose my pet on Flea5X Plus?

Contact your veterinarian or veterinary emergency room.

What should I avoid while giving Flea5X Plus to my pet?

DO NOT USE FLEA5X FOR DOGS ON CATS. DO NOT USE FLEA5X FOR CATS ON DOGS. Do not use on cats or kittens under 1.5 lbs or under 8 weeks of age. Do not use on dogs or puppies under 4 lbs or under 8 weeks of age. Use the entire contents on each pet. Do not split one tube between pets. Do not use multiple tubes on one pet. Weigh your dog to ensure you are applying the right dose formulated for the weight of your dog.

What other drugs will affect Flea5X Plus?

Certain medications can interact with pesticides. Sensitivities may occur after using ANY pesticide product on pets.

How to Use

Flea5X Plus Directions:

  • Remove the Flea5X Plus product tubes from the package. Separate one tube from the others.
  • Hold the Flea5X Plus tube with notched end pointing up and away from your face and body. Use scissors to cut off the narrow end at the notches along the line.
  • Invert the tube over the back of your pet's neck and use the open end to part your pet's hair.
  • Squeeze the tube firmly to apply all of the solution to your pet's skin, as a spot to your pet's back between the shoulder blades.
  • Do not apply more often than once every 30 days.
Tip:

Wait until application site is fully dry (usually 24 hours) before bathing your pet or letting your pet go swimming.

Flea5X Plus - Generic to Frontline Plus Dosage for Dogs/Puppies (8 weeks of age or older):

Dogs/Puppies (8 weeks of age or older):
WeightDosage
4 to 22 lbsApply contents of 1 applicator once a month (0.67 mL)
23-44 lbsApply contents of 1 applicator once a month (1.34 mL)
45-88 lbsApply contents of 1 applicator once a month (2.68 mL)
89-132 lbsApply contents of 1 applicator once a month (4.02 mL)
Over 1.5 lbsApply contents of 1 applicator once a month (0.50 mL)
Flea5X Plus - Generic to Frontline Plus Dosage for Horses:
Horses
Do not use!
Ingredients

Flea5X Plus Ingredients:

Flea5X Plus for Dogs & Puppies 8 weeks or older, 4 to 22 lbs:
Active ingredients (per 0.67 ml applicator)Amount
Fipronil9.80%
(S)-methoprene8.80%
Other Ingredients81.40%
Flea5X Plus for Dogs & Puppies 8 weeks or older, 23-44 lbs:
Active ingredients (per 1.34 ml applicator)Amount
Fipronil9.80%
(S)-methoprene8.80%
Other ingredients81.40%
Flea5X Plus for Dogs & Puppies 8 weeks or older, 45-88 lbs:
Active Ingredients (per 2.68 ml applicator)Amount
Fipronil9.80%
(S)-methoprene8.80%
Other Ingredients81.40%
Flea5X Plus for Dogs & Puppies 8 weeks or older, 89-132 lbs:
Active Ingredients (per 4.02 ml applicator)Amount
Fipronil9.80%
(S)-methoprene8.80%
Other Ingredients81.40%
Flea5X Plus for Cats & Kittens 8 weeks or older, over 1.5 lbs:
Active ingredients (per 0.50 ml applicator)Amount
Fipronil9.80%
(S)-methoprene11.80%
Other Ingredients78.40%
Customer Reviews
Flea5X Plus - Generic to Frontline Plus is rated 2.9 out of 5 by 375.
Rated 5 out of 5 by from Very effective. As effective as any of the name brands. We do 4 dogs (three middle sized and one very large) as well as living Florida, where fleas don't die but hibernate during our brief cold spells (I know but it seems like that.) We are very happy with FleaX Plus.
Date published: 2017-12-29
Rated 2 out of 5 by from Worked Sort Of Used 3 of the six doses and my English Setter was flea free however within a week after dose 4 she had fleas and she’s mostly an indoor dog. Will be trying another product and not going generic. you Cannot reapply for 30 days so i have a wasted dose since I need to find a solution now.
Date published: 2017-12-08
Rated 3 out of 5 by from Unpleasant feel and odor but works This product does the job on my 11 pound shorthaired Dachshund but I have stopped using it because it is so nasty to deal with. I came to dread the monthly application because the liquid was sticky, kind of greasy, and really smelly. Everything she touched for several days afterward ended up with an unpleasant residue, including me! At least I won't have fleas or ticks, either. I didn't have that problem with other topicals.
Date published: 2017-12-08
Rated 5 out of 5 by from As effective as Frontline We'd been using Frontline brand for our indoor-outdoor Russian Blue cat and switched to this generic product and has been equally as effective. No fleas or flea bites. No skin issues or irritation to our kitty either. We use the product year-round.
Date published: 2017-12-02
Rated 2 out of 5 by from Did Not work for Ticks I bought this for my cocker spaniel. It seemed to work for fleas, but we live near a wooded area. cockers are hunting dogs, and mine likes to hunt scents in the grass. I found 4 ticks fully bloated on him after using this product. I will not use the other 2 dises and will switch to Advantage.
Date published: 2017-12-01
Rated 1 out of 5 by from Did not work I used fro 3 months straight and it did not work. Pay for the real frontline...
Date published: 2017-11-29
Rated 5 out of 5 by from Good Product I had a good experience with this product. All 3 of my dogs got fleas and we showered them and applied the flea medicine. Their itch and bites stopped within the week.
Date published: 2017-11-21
Rated 1 out of 5 by from Didn’t work I bought this to try and save some money. It didn’t work and now my dogs have fleas and ticks. Guess it’s true you get what you pay for.
Date published: 2017-11-20
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Q&A

Do you have to have prescription for meds

Asked by: Lonesome2
Thank you for your question. Flea 5x Plus does not require a veterinarians prescription.
Answered by: Crystal PetMed Pro
Date published: 2018-01-09

What country is this product manufactured in?

Asked by: Abbys Mom
This product is manufactured in the U.S.
Answered by: Cherley Petmeds Pro
Date published: 2017-11-07

How well does this work I have a big dog 

Asked by: Pibb
Thank you for your question. Flea5X Plus contains fipronil to quickly kill adult fleas, ticks and chewing lice on your pet. Flea5X Plus also contains (S)-methoprene, an insect growth regulator that kills flea eggs and larvae to help end the flea life cycle. In addition to killing adult fleas and preventing reinfestation, Flea5X Plus is effective against ticks such as the brown dog tick, the American dog tick, the lone star tick and the deer tick, including those that may transmit Lyme disease. Choose Flea5X Plus for a great savings over leading comparable brands and get the same effective protection for your pet.
Answered by: Crystal PetMed Pro
Date published: 2018-01-07

Will this product eliminate ear mites like Revolution does?

Asked by: debgbrick
Thank you for your question. This product does not eliminate, treat or prevent ear mites.
Answered by: Crystal PetMed Pro
Date published: 2017-10-19

Is there an oral monthly pill for flea and tick that can be used on dogs without a prescription from the Vet

Asked by: Terry
The oral flea and tick preventatives currently available require a prescription from your veterinarian.
Answered by: Lisa M
Date published: 2017-10-30

Yes i need to know if i can get flea medicine for kttens 3weeks old  thank you

Asked by: carolyn
We give our kittens a warm bath with a tiny amount of dawn then get a cup with hot water and dawn dish soap and use a cat flea comb with a tweasers to remove all the fleas and drop them inside the cup. Takes a little bit of time but worth it since fleas are dangerous on kittens.
Answered by: Tammy
Date published: 2017-10-07

I mistakenly ordered the wrong weight on my last order which I received on Saturday. I have been using the Flea 5X Plus for a long time. What shall I do? I ordered the largest weight one when my largest dog is 70 lbs. & my other two are 50 lbs.

Asked by: Dede
Thank you for your question. We would be more than happy to process an exchange so you can have the correct dose for your furry pals. Please give us a call at 1-800-738-6337 for further assistance.
Answered by: Crystal PetMed Pro
Date published: 2017-10-30

Why can't the dog formula be used on cats?

Asked by: Kgust312
We do carry Flea 5x Plus for cats. Please see the link below. https://www.1800petmeds.com/Flea5X+Plus+++Generic+to+Frontline+Plus-prod11480.html?Ntt=flea+5x
Answered by: Cherley Petmeds Pro
Date published: 2017-09-05
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