PETMED EXPRESS D/B/A 1-800-PETMEDS ANNOUNCES SECOND QUARTER FINANCIAL RESULTS – NET INCOME INCREASES 22%

Pompano Beach, Florida, October 23, 2006 - PetMed Express, Inc. (NASDAQ: PETS) today announced its financial results for the quarter ended September 30, 2006. Net income was $3.3 million, or $0.14 diluted per share, for the quarter ended September 30, 2006, compared to net income of $2.7 million, or $0.11 diluted per share, for the quarter ended September 30, 2005, an increase to net income of 22%. Net sales for the quarter ended September 30, 2006 were $43.8 million, compared to $38.7 million for the quarter ended September 30, 2005, an increase of 13%. Net income was $8.1 million, or $0.33 diluted per share, for the six months ended September 30, 2006, compared to net income of $6.3 million, or $0.26 diluted per share, for the six months ended September 30, 2005, an increase to net income of 29%. Net sales for the six months ended September 30, 2006 were $94.5 million, compared to $82.3 million for the six months ended September 30, 2005, an increase of 15%. Approximately 62% of all sales were placed on the Company’s website for the second quarter, compared to 55% for the same quarter in the prior year.

Menderes Akdag, CEO and President, commented: “We are pleased to report that our retail reorder sales increased by 23%, from $22.9 million to $28.1 million for the quarters ended September 30, 2005 and 2006, respectively. For the six months ended September 30, 2006 our retail reorder sales increased by 28% to $62.0 million from $48.6 million for the six months ended September 30, 2005. We are currently focused on optimizing our advertising campaigns and improving our current service levels to capture additional market share. We are also pleased to report that net cash provided by operating activities increased by $1.5 million, from $12.7 million for the six months ended September 30, 2005 to $14.2 million for the six months ended September 30, 2006.”

This morning at 8:30 A.M. Eastern Time, Mr. Akdag will host a conference call to review the quarter’s financial results. To access the call which is open to the public, dial (888) 455-1758 (toll free) or (312) 470-7365. Callers will be required to supply PETMEDS as the passcode. For those unable to participate in the live event, the call will be available for replay from 10 A.M. on October 23, 2006 until November 6, 2006 at 10:59 P.M. To access the replay, call (866) 422-8069 (toll free) or (203) 369-0828, and enter passcode 5500.

Founded in 1996, PetMed Express is America’s Largest Pet Pharmacy, delivering prescription and non-prescription pet medications and other health products for dogs, cats and horses at competitive prices direct to the consumer through its 1-800-PetMeds toll free number and on the Internet through its website at www.1800petmeds.com.

This press release may contain “forward-looking” statements, as defined in the Private Securities Litigation Reform Act of 1995 or by the Securities and Exchange Commission, that involve a number of risks and uncertainties, including the Company’s ability to meet the objectives included in its business plan. Important factors that could cause results to differ materially from those indicated by such “forward-looking” statements are set forth in Management’s Discussion and Analysis of Financial Condition and Results of Operations in the PetMed Express Annual Report on Form 10-K for the year ended March 31, 2006. The Company’s future results may also be impacted by other risk factors listed from time to time in its SEC filings, including, but not limited to, the Company's Form 10-Q and its Annual Report on Form 10-K.

For investment relations contact PetMed Express, Inc., Bruce S. Rosenbloom, CFO, 954-979-5995.