NexGard COMBO Topical Flea & Tick Protection plus Heartworm Disease Preventive for Cats

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What is NexGard® COMBO for Cats?

NexGard® COMBO for Cats kills fleas and ticks, prevents heartworm disease, and treats and controls hookworms, roundworms and tapeworms. NexGard® COMBO topical solution is parasite protection for cats from the maker of vet-recommended NexGard® (afoxolaner) and HEARTGARD® Plus (ivermectin/pyrantel). All cats need parasite protection, even indoor cats. Applied monthly, NexGard® COMBO is designed to deliver parasite protection to your cat year-round with an easy-to-use applicator. And it’s the first and only broad-spectrum solution that treats and kills tapeworms. NexGard® COMBO topical solution is one-and-done monthly protection formulated specifically for cats. It is safe and approved for cats and kittens as young as 8 weeks old, weighing 1.8 pounds or more. NexGard® COMBO requires a prescription from your veterinarian.

Suitable for:

Cats and kittens as young as 8 weeks old, weighing 1.8 pounds or more

Benefits:

  • Year-round protection from harmful parasites when applied monthly
  • Convenient one-and-done dosing that lasts for a full month
  • First and only feline broad spectrum parasite protection that kills tapeworms.
  • Kills adult fleas before they can lay eggs
  • Kills black-legged ticks and lone star ticks
  • Effectively prevents heartworm disease
  • Treats and controls hookworms, roundworms, and tapeworms

How does NexGard® COMBO for Cats work?

NexGard® COMBO topical solution contains three active ingredients (esafoxolaner, eprinomectin and praziquantel) to protect against fleas, ticks, heartworm disease, roundworms, hookworms and tapeworms in cats and kittens 8 weeks of age and older and weighing 1.8 lbs. or greater.

Caution:

NexGard® COMBO is for topical use only in cats. Use with caution in cats with a history of seizures or neurologic disorders. Not for human use. Keep this and all drugs out of sight and reach of children. Avoid direct contact with the application site for 4 hours or until visibly dry. This product may act as a mild to moderate eye irritant. Keep product in the original packaging until use. Wash hands after product administration. For more information, refer to the full prescribing information.

How should I store this product?

Store at 59°–86°F (15°–30° C). Brief periods up to 104°F (40°C) are permitted. Protect from light.

Brand Name:

NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution)

What is the most important information I should know about NexGard® COMBO for Cats?

NexGard® COMBO is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (fourth stage larval and adult Toxocara cati), hookworm (fourth stage larval and adult Ancylostoma tubaeforme; adult Ancylostoma braziliense), and tapeworm (Dipylidium caninum) infections. NexGard® COMBO kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations and the treatment and control of Ixodes scapularis (black-legged tick) and Amblyomma americanum (lone star tick) infestations for one month in cats and kittens 8 weeks of age and older, and weighing 1.8 lbs or greater.

What should I discuss with my veterinarian before giving NexGard® COMBO for Cats to my pet?

Tell your veterinarian if your cat is pregnant, lactating or has a history of seizures. The safety of NexGard® COMBO has not been tested in breeding, pregnant, or lactating cats. Esafoxolaner, one of the ingredients in NexGard® COMBO, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in cats receiving isoxazoline class drugs, even in cats without a history of seizures. Use with caution in cats with a history of seizures or neurologic disorders.

How should NexGard® COMBO for Cats be given/administered?

Use NexGard® COMBO topical solution by following the instructions and dosage guidelines provided by your veterinarian or refer to the full prescribing information. Each dose provides protection from fleas and ticks, heartworm disease, roundworms, hookworms, and tapeworms. NexGard® COMBO topical solution is intended for topical application only. Do not inject, do not administer orally or via any other route.

What are the potential side effects of NexGard® COMBO for Cats?

The most frequently reported adverse reactions include vomiting, application site reactions, and anorexia

What happens if I miss giving a dose of NexGard® COMBO for Cats?

If a dose is missed and a 30-day interval between doses is exceeded, administer NexGard® COMBO immediately and resume the monthly dosing schedule.

What happens if I overdose my pet on NexGard® COMBO for Cats?

Contact your veterinarian immediately.

What special precautions are there?

Esafoxolaner, one of the ingredients in NexGard® COMBO, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in cats receiving isoxazoline class drugs, even in cats without a history of seizures. Use with caution in cats with a history of seizures or neurologic disorders. Do not administer orally. Cats may salivate excessively if NexGard® COMBO is accidentally administered orally or is ingested through licking/grooming the application site. The safety of NexGard® COMBO has not been tested in breeding, pregnant, or lactating cats. The safety of NexGard® COMBO has not been tested in kittens less than 8 weeks of age or weighing less than 1.8 lbs. (0.8 kg)

What should I avoid while giving NexGard® COMBO for Cats to my pet?

There are no known contraindications for the use of NexGard® COMBO.

NexGard® COMBO for Cats Directions:

  • Administer the entire contents of a NexGard® COMBO unit applicator topically once a month.
  • For heartworm disease prevention, apply once monthly for at least three months after last exposure to mosquitoes.
  • 1. Use scissors to cut the blister along the dotted line.
  • 2. Then pull the lid away.
  • 3. Remove the applicator from the package and hold it upright. Pull back the plunger slightly.
  • 4. Twist and pull off the cap.
  • 5. Part the hair on the midline of the neck, between the base of the skull and the shoulder blades until the skin is visible. Place the tip of the applicator on the skin and apply the entire contents directly onto the skin in one spot. The product should be applied to dry skin on an area where the cat cannot lick it off. If the weight of the cat requires a second application, apply the contents in the same manner as described above in the same location.
  • 6. Wash hands after use with soap and water.
Tip:

Carefully follow the application instructions on the packaging label for best results.

NexGard® COMBO for Cats Dosage:

Cats and Kittens (8 weeks of age and older, and weighing 1.8 lbs or greater)
Cat Weight Dosage (Once a Month)
1.8-5.5 lbs 1 (0.3 ml) applicator
5.6-16.5 lbs 1 (0.9 ml) applicator
16.6-22 lbs 1 (0.3 ml) + 1 (0.9 ml) applicator
22.1-33 lbs 1 (0.9 ml) + 1 (0.9 ml) applicator
NexGard® COMBO for Cats Dosage for Dogs
Dogs
Do not use!
NexGard® COMBO for Cats Dosage for Horses
Horses
Do not use!

NexGard® COMBO for Cats Ingredients:

NexGard® COMBO for Cats 1.8-5.5 lbs. (Purple Box)
Active Ingredient Amount (per applicator)
Esafoxolaner 3.6 mg
Eprinomectin 1.2 mg
Praziquantel 24.9 mg
NexGard® COMBO for Cats 5.6-16.5 lbs. (Yellow Box)
Active Ingredient Amount (per applicator)
Esafoxolaner 10.8 mg
Eprinomectin 3.6 mg
Praziquantel 74.7 mg
Product Details Product Details

What is NexGard® COMBO for Cats?

NexGard® COMBO for Cats kills fleas and ticks, prevents heartworm disease, and treats and controls hookworms, roundworms and tapeworms. NexGard® COMBO topical solution is parasite protection for cats from the maker of vet-recommended NexGard® (afoxolaner) and HEARTGARD® Plus (ivermectin/pyrantel). All cats need parasite protection, even indoor cats. Applied monthly, NexGard® COMBO is designed to deliver parasite protection to your cat year-round with an easy-to-use applicator. And it’s the first and only broad-spectrum solution that treats and kills tapeworms. NexGard® COMBO topical solution is one-and-done monthly protection formulated specifically for cats. It is safe and approved for cats and kittens as young as 8 weeks old, weighing 1.8 pounds or more. NexGard® COMBO requires a prescription from your veterinarian.

Suitable for:

Cats and kittens as young as 8 weeks old, weighing 1.8 pounds or more

Benefits:

  • Year-round protection from harmful parasites when applied monthly
  • Convenient one-and-done dosing that lasts for a full month
  • First and only feline broad spectrum parasite protection that kills tapeworms.
  • Kills adult fleas before they can lay eggs
  • Kills black-legged ticks and lone star ticks
  • Effectively prevents heartworm disease
  • Treats and controls hookworms, roundworms, and tapeworms

How does NexGard® COMBO for Cats work?

NexGard® COMBO topical solution contains three active ingredients (esafoxolaner, eprinomectin and praziquantel) to protect against fleas, ticks, heartworm disease, roundworms, hookworms and tapeworms in cats and kittens 8 weeks of age and older and weighing 1.8 lbs. or greater.

Caution:

NexGard® COMBO is for topical use only in cats. Use with caution in cats with a history of seizures or neurologic disorders. Not for human use. Keep this and all drugs out of sight and reach of children. Avoid direct contact with the application site for 4 hours or until visibly dry. This product may act as a mild to moderate eye irritant. Keep product in the original packaging until use. Wash hands after product administration. For more information, refer to the full prescribing information.

How should I store this product?

Store at 59°–86°F (15°–30° C). Brief periods up to 104°F (40°C) are permitted. Protect from light.

Brand Name:

NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution)

What is the most important information I should know about NexGard® COMBO for Cats?

NexGard® COMBO is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (fourth stage larval and adult Toxocara cati), hookworm (fourth stage larval and adult Ancylostoma tubaeforme; adult Ancylostoma braziliense), and tapeworm (Dipylidium caninum) infections. NexGard® COMBO kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations and the treatment and control of Ixodes scapularis (black-legged tick) and Amblyomma americanum (lone star tick) infestations for one month in cats and kittens 8 weeks of age and older, and weighing 1.8 lbs or greater.

What should I discuss with my veterinarian before giving NexGard® COMBO for Cats to my pet?

Tell your veterinarian if your cat is pregnant, lactating or has a history of seizures. The safety of NexGard® COMBO has not been tested in breeding, pregnant, or lactating cats. Esafoxolaner, one of the ingredients in NexGard® COMBO, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in cats receiving isoxazoline class drugs, even in cats without a history of seizures. Use with caution in cats with a history of seizures or neurologic disorders.

How should NexGard® COMBO for Cats be given/administered?

Use NexGard® COMBO topical solution by following the instructions and dosage guidelines provided by your veterinarian or refer to the full prescribing information. Each dose provides protection from fleas and ticks, heartworm disease, roundworms, hookworms, and tapeworms. NexGard® COMBO topical solution is intended for topical application only. Do not inject, do not administer orally or via any other route.

What are the potential side effects of NexGard® COMBO for Cats?

The most frequently reported adverse reactions include vomiting, application site reactions, and anorexia

What happens if I miss giving a dose of NexGard® COMBO for Cats?

If a dose is missed and a 30-day interval between doses is exceeded, administer NexGard® COMBO immediately and resume the monthly dosing schedule.

What happens if I overdose my pet on NexGard® COMBO for Cats?

Contact your veterinarian immediately.

What special precautions are there?

Esafoxolaner, one of the ingredients in NexGard® COMBO, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in cats receiving isoxazoline class drugs, even in cats without a history of seizures. Use with caution in cats with a history of seizures or neurologic disorders. Do not administer orally. Cats may salivate excessively if NexGard® COMBO is accidentally administered orally or is ingested through licking/grooming the application site. The safety of NexGard® COMBO has not been tested in breeding, pregnant, or lactating cats. The safety of NexGard® COMBO has not been tested in kittens less than 8 weeks of age or weighing less than 1.8 lbs. (0.8 kg)

What should I avoid while giving NexGard® COMBO for Cats to my pet?

There are no known contraindications for the use of NexGard® COMBO.

NexGard® COMBO for Cats Directions:

  • Administer the entire contents of a NexGard® COMBO unit applicator topically once a month.
  • For heartworm disease prevention, apply once monthly for at least three months after last exposure to mosquitoes.
  • 1. Use scissors to cut the blister along the dotted line.
  • 2. Then pull the lid away.
  • 3. Remove the applicator from the package and hold it upright. Pull back the plunger slightly.
  • 4. Twist and pull off the cap.
  • 5. Part the hair on the midline of the neck, between the base of the skull and the shoulder blades until the skin is visible. Place the tip of the applicator on the skin and apply the entire contents directly onto the skin in one spot. The product should be applied to dry skin on an area where the cat cannot lick it off. If the weight of the cat requires a second application, apply the contents in the same manner as described above in the same location.
  • 6. Wash hands after use with soap and water.
Tip:

Carefully follow the application instructions on the packaging label for best results.

NexGard® COMBO for Cats Dosage:

Cats and Kittens (8 weeks of age and older, and weighing 1.8 lbs or greater)
Cat Weight Dosage (Once a Month)
1.8-5.5 lbs 1 (0.3 ml) applicator
5.6-16.5 lbs 1 (0.9 ml) applicator
16.6-22 lbs 1 (0.3 ml) + 1 (0.9 ml) applicator
22.1-33 lbs 1 (0.9 ml) + 1 (0.9 ml) applicator
NexGard® COMBO for Cats Dosage for Dogs
Dogs
Do not use!
NexGard® COMBO for Cats Dosage for Horses
Horses
Do not use!

NexGard® COMBO for Cats Ingredients:

NexGard® COMBO for Cats 1.8-5.5 lbs. (Purple Box)
Active Ingredient Amount (per applicator)
Esafoxolaner 3.6 mg
Eprinomectin 1.2 mg
Praziquantel 24.9 mg
NexGard® COMBO for Cats 5.6-16.5 lbs. (Yellow Box)
Active Ingredient Amount (per applicator)
Esafoxolaner 10.8 mg
Eprinomectin 3.6 mg
Praziquantel 74.7 mg
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Kills fleas & ticks fast, all month long
It's available with an easy-to-use applicator – for convenient monthly administration year-round.

NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) kills fleas and ticks, prevents heartworm
disease, treats and controls roundworms, hookworms, and tapeworms. It's available with an easy-to-use applicator – for
convenient monthly administration year-round. It’s safe and approved for cats and kittens
as young as 8 weeks old, weighing 1.8 lbs or more.

ALL CATS NEED PARASITE PROTECTION
Easy to apply

Easy to apply
topical solution

Kills tapeworms

First and only feline
broad-spectrum parasite
protection that kills tapeworms

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never miss a dose

Safe for kittens

Safe for cats & kittens as
young as 8 weeks old,
weighing 1.8 lbs or more

About NexGard® COMBO topical solution

About NexGard® COMBO topical solution

NexGard® COMBO topical solution is a convenient, one-and-done monthly treatment that kills fleas and ticks, prevents heartworms, treat and controls roundworms, hookworms, and tapeworms.

It is easy to apply, FDA-approved, and safe for cats and kittens as young as 8 weeks old, weighing 1.8 lbs or more.

All cats, even indoor cats, should be protected year-round from parasites. NexGard® COMBO topical solution is the only feline broad-spectrum parasite protection that treats and kills tapeworms.

Use with caution in cats with a history of seizures or neurologic disorders.

Prevents flea infestations

Prevents flea infestations

Whether your cat is a homebody or a neighborhood adventurer, there's a chance fleas will find a way onto your cat.

Fleas can be carried into your home by other pets or brought indoors by family members and guests on their skin or clothing.

Protects against ticks

Ticks are blood-sucking parasites that feed on cats and other animals. All cats should be protected, even indoor cats. Ticks are found year-round across the country and can carry harmful diseases.

Protects against ticks
Treats and controls roundworms, hookworms and tapeworms

Treats and controls roundworms, hookworms and tapeworms

These are all common parasites that are risks to your cat. Cats can pick up roundworms while grooming themselves after walking or digging through contaminated soil.

Cats can pick up hookworms by walking or digging up contaminated soil, then ingesting hookworm larvae while grooming, or from hunting and ingesting other hosts. And cats can contract tapeworms by ingesting infected fleas while grooming.

Effective heartworm prevention

While cats are not the ideal hosts for heartworms, they can still develop heartworm disease. Adult heartworms are a year-round threat and can cause illness and even death in cats.

Heartworms are transmitted by mosquitoes, and your cat can get heartworm disease from a single mosquito bite.

Effective heartworm prevention

NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is for topical use only in cats. Use with caution in cats with a history of seizures or neurologic disorders. The most frequently reported adverse reactions include vomiting, application site reactions, and anorexia. If ingested, hypersalivation may occur. Avoid direct contact with application site until visibly dry. For heartworm disease prevention, apply once monthly for at least 3 months after last exposure to mosquitoes. For more information, contact your veterinarian or refer to the full prescribing information.

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