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Advantage II - Frontline Plus - Seresto| Kills Fleas |
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| Repels Fleas |
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| Kills Flea eggs and Larvae |
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| Kills Ticks |
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| Repels Ticks |
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| Kills and/or Repels Mosquitoes |
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| Prevents Heartworm |
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| Other Parasites Information | Treats, Prevents, and Controls Lice Infestations | Eliminates infestations with chewing lice, aids in the control of sarcoptic mange infestation | Kills biting lice plus aids in the treatment & control of sarcoptic mange on dogs. |
| Waterproof (shampooing once a week can reduce effectiveness) |
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| Safe for pregnant or nursing Pets | Consult your veterinarian |
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Consult veterinarian before use. |
| How long does it take to work | Kills fleas in 12 hours | Kills Fleas within 12 hours and Ticks within 48 hours | Kills fleas within 24 hours, and reinfesting fleas are killed in 2 hours. Reinfesting ticks are repelled and/or killed in 6 hours. |
| Taste | Applied to Skin | Applied to Skin | Collar |
| Active Ingredient(s) | Imidacloprid/Pyriproxyfen | Fipronil/(S)-Methoprene | Flumethrin, Imidacloprid |
| RX Required |
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| Video | /images/products/video/petmeds-flea-preventative-advantage.flv | /images/products/video/petmeds-flea-preventative-frontline-plus.flv | |
| Vet Review | The non-greasy, non-odor formulation is a definite plus when used on sensitive patients, especially cats. I find that advantage kills fleas and larvae more quickly than some of the other products out there, often resulting in quicker relief of flea allergy dermatitis symptoms in dogs and cats. Overall I have found it quite safe and have seen the fewest topical or rare systemic reactions in my practice over the years. The main disadvantage I have found is that in heavy flea infestations that the efficacy may wear off in less than one month, necessitating some vets to recommend more frequent off label use of this product every few weeks. It also does not control ticks as well on dogs and cats. I find that advantage works most effectively when combined with good environmental flea control at home. | I find that the effective combination of an ingredient like fipronil, along with the insect growth regulator methoprene, provides the best spectrum of activity and protection against all stages of the flea life cycle from egg through larval stage on to adult. Because of these two main ingredients and their method of action, I find that clients don't have to treat the environment as much. I find that this product tends to be safer in smaller breed animals when compared to its competition. I find its tick efficacy quite good. The fact that it is waterproof also allows clients, whose pets swim frequently, to confidently use this product during the swimming months. I also find that this product works the longest for fleas, while some of the competitive products have to be reapplied before the end of the month. The lack of label efficacy against mosquitoes and flies, as well as the fact that this product does not repel fleas or ticks are the two main disadvantages. As with any insecticidal products, I find that every pet is an individual, in terms of which of the products works best on them. When I am dealing with more of a flea issue in a patient, this is the product I will likely reach for first. | In recent years, the company Bayer has developed a revolutionary flea/tick collar for both dogs and cats that is highly effective, especially in flea control, as well as providing moderately effective tick control. The most exciting aspect of this product is that it provides BOTH repelling and killing of fleas and ticks for up to 8 months!! While it is somewhat expensive, it is actually cheaper than purchasing 8 months of Revolution, Advantage or Frontline. In many areas of the country, this protection will last the entire flea and tick season, by just properly applying the collar. Another major advantage over collars developed in prior years (i.e. Preventic collar) is that Seresto is water resistant, and can be worn with confidence, even by dogs who frequently swim. The collar also has no odor, as well as a powdery, soft feel, in addition to leaving no greasy topical residue, like many of the other topical flea and tick products available. The collar is safe if chewed and/or even eaten by the pet, which was a problem with the old Amitraz based collars such as the Preventic collar. The Bayer company has also made it radioopaque, in case an overzealous pet did ingest the collar, so as to allow radiographic tracing and/or location should it possibly get caught up in the intestinal tract. The collar also has unique technology, in that the release of the active ingredients is triggered by friction of the movement of the pet's hair and body heat. The cat collar even has a break-away apparatus to allow for the pet to safely detach from the collar should it get caught on something outside. The reflectors on the dog product also allow the dog to be seen during the hours of darkness. While the collar is very safe for most pets, I have occasionally and rarely seen reactions in sensitive, geriatric or chronically ill pets. These typically involve transient itching, redness and hair loss at the site of adherence to the skin. While most of the time this will resolve on its own in a week or two, occasionally pets will develop enough irritation where the collar may need to be removed. The major rare systemic reactions seen in sensitive pets are mild lethargy and decrease in energy, but even more rare is the development of neurological symptoms, including weakness and/or seizures. I don't recommend that it be used in pets with a history of seizures and/or neurological sensitivity or reactions. While it is amazing for killing and repelling all stages of the flea life cycle quite quickly, it can sometimes take up to several days for the maximal effects to be seen with tick control and prevention. I, therefore, give this product an overall rating of a 4 out of 5, with an ease of compliance and efficacy of a 4.5 out of 5. |
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors.
The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies.
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