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Proin

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Proin?

Proin is an aid in the management of urinary incontinence in dogs. Proin requires a prescription from your veterinarian, and is considered a controlled substance in Arkansas, Iowa, Louisiana and Oregon.

Proin is unavailable to be shipped to Arkansas, Iowa, Louisiana, Oregon or Internationally.

For:

Dogs

Benefits:
  • Is a supplement for urinary incontinence in dogs
  • Ensures sustained phenylpropanolamine levels in the blood stream and may help reduce the conditions often associated with high levels of phenylpropanolamine such as: decreased appetite, changes in heart rate, increased blood pressure, hyperexcitability
How it Works:

Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage.

Cautions:

Don't give Proin with ephedrine or epinephrine, and don't give it within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar. Possible side effects can occur, including restlessness, or loss of appetite, difficulty breathing, hives, and swelling of the lips, tongue, or face. If these or any other side effects occur, contact your veterinarian immediately. Proin is unavailable to be shipped to Arkansas, Iowa, Louisiana, Oregon or Internationally.

Brand Name:

Proin (PRN Pharmacal)

Generic Name:

Phenylpropanolamine

What is the most important information I should know about Proin:

Proin is a prescription medication for veterinary use in dogs. Proin is available as 25mg, 50mg and 75mg chewable, liver flavor tablets. Proin may cause restlessness, irritability, or loss of appetite.

What is Proin:

Proin is an adrenergic agent used as a supplemental product for urinary incontinence in dogs. Proin may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving Proin to my pet:

Tell your veterinarian if your pet has ever had an allergic reaction to this medication. Tell your veterinarian if your pet has glaucoma, hyperthyroid disease, diabetes, heart problems or high blood pressure. Tell your veterinarian if your pet is pregnant or lactating.

How should this medication be given:

The usual dose for dogs is 0.4-0.8mg/pound every 12 hours. Give Proin exactly as directed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Proin at room temperature away from moisture and heat. Keep this medication away from children and pets. 

What happens if I miss giving a dose:

Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose the pet:

Seek emergency veterinary medical treatment. Symptoms of overdose may include increased blood pressure, increased heart rate, seizures or coma.

What should I avoid while giving Proin to my pet:

Do not give Proin with ephedrine or epinephrine and do not give within 2 weeks of using an MAOi such as selegiline or Preventic Collar.

What are the possible side effects of Proin:

Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.

What other drugs will affect Proin:

Before giving Proin, tell your veterinarian if your pet is being given digoxin, NSAIDs such as aspirin or Rimadyl, tricyclic antidepressants such as clomipramine, and beta blockers such as atenolol, or any other prescription or over the counter medications. 

Where can I get more information:

Your pharmacist has additional information about Proin written for health professionals that you may read.

How to Use

Proin Directions:

  • Proin liver flavored chewable tablets are available by prescription for use in dogs to treat urinary incontinence.
  • Proin may cause restlessness, irritability, or loss of appetite.
  • Tell your veterinarian about any other medication you may be giving your pet.
Tip:

Give this medication exactly as directed by your veterinarian. Do not exceed 1.8mg/lb per day. The medication may be given with food.

Proin Dosage for Dogs:

Dogs:
WeightDosage
All weightsThe usual dose for dogs is 0.4-0.8mg/pound every 12 hours.
Proin Dosage for Cats:
Cats
Do not use!
Proin Dosage for Horses:
Horses
Do not use!
Storage:

Should be stored at room temperature away from moisture and heat. Keep this medication away from children and pets.

Ingredients

Proin Ingredients:

Proin Chewable Flavor Tabs 25 mg
Active IngredientsStrength
Phenylpropanolamine25 mg
Proin Chewable Flavor Tabs 50 mg
Active IngredientsStrength
Phenylpropanolamine50 mg
Proin Chewable Flavor Tabs 75 mg
Active IngredientsStrength
Phenylpropanolamine75 mg
Customer Reviews
Proin is rated 4.7 out of 5 by 680.
Rated 5 out of 5 by from Starting working immediately Our 5 year old spayed boxer/lab mixed breed started having accidents in her bed while sleeping. After seeing my dog’s shame from wetting her bed and reassurance from my vet that it was safe, we started a twice daily regimen. Since starting Prion (about 5 months now), we have had no accidents and I have not noticed any visible side effects. She is as happy and active as she was before!
Date published: 2018-01-01
Rated 5 out of 5 by from The Perfect Combination: Proin & Incurin In the last year, my female spayed dog starting having problems with incontinence. Sometimes a trickle coming out of her while lying down and other times full bladder loss. With the help of my awesome vet, he has helped me find the perfect combination of dosing Incurin and Proin to now only 1 accident within a 2 week period of time! Instead of almost daily and/or multiple times per day bladder loss.
Date published: 2017-12-27
Rated 4 out of 5 by from Love this medication's effectiveness! Haylie has been taking Pronin for two years. It significantly reduces her incontinence,
Date published: 2017-12-23
Rated 5 out of 5 by from Good medication. This is a very good product. Lady has been on it for years with very good results. Glad I could get it through Petmeds.
Date published: 2017-12-19
Rated 5 out of 5 by from Proin My dear Bobbi has been on Proin for quite a few years and seems to be doing great on it.....We are thankful to have found something to help her.
Date published: 2017-12-17
Rated 5 out of 5 by from Does the trick! We adopted Sachi from our local shelter and had already been spayed & tattooed. I don't know if during the surgery her bladder or muscles were knicked but she would dribble. The vet suggested we try this as the dosage was adjustable to the degree of the problem. For Sachi a quarter of a tablet a day does the trick. No more dribble!
Date published: 2017-12-12
Rated 5 out of 5 by from Greatly product! Our dog has been on Proin for years and has kept her incontinent free. No side affects noted.
Date published: 2017-12-08
Rated 5 out of 5 by from No More Leaks Proin is doing the job. With that and hormone replacement, our girl has been leak free for two years now. It was pretty bad before the pills. I have cut back to 3/4 pill a day and it is working fine. Started at 2 pills/day. Also have cut back hormones from every 3 days to every 8. I am continuing to cut back on hormones, just doing it very gradually.
Date published: 2017-12-03
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Q&A

Do you need a prescription 

Asked by: Chopper
Thank you for your question. Proin does require a prescription.
Answered by: Crystal PetMed Pro
Date published: 2017-12-03

Dosage for a dog weighing 25lbs

Asked by: kelly
Thank you for your question. The usual dose for dogs is 0.4-0.8mg/pound every 12 hours. However as the medication is a prescription medication it should be given exactly as directed by your veterinarian.
Answered by: Crystal PetMed Pro
Date published: 2017-09-25

How long should my dog be on,proin,?

Asked by: Jazmain
Proin may be administerd on a maintenance basis. Your veterinarian will determine the appropriate treatment duration for your pet.
Answered by: Lisa M
Date published: 2017-09-20

Can I give my dog something other than proin with out scripts

Asked by: Cheryl
Thank you for your question. Please consult with your veterinarian for the best medication for your pet. You should always consult with them prior to administering any OTC/Rx medication for safety and efficacy.
Answered by: leanniejo
Date published: 2017-08-21

Can this be frozen when mixed with hamburger?

Asked by: Jjm21
Thank you for your question. Give Proin exactly as directed by the veterinarian. If you do not understand the directions, ask the veterinarian to explain them to you. Store Proin at room temperature away from moisture and heat.
Answered by: leanniejo
Date published: 2017-11-06

I have a hand written prescription from my vet Can I scan this to you?

Asked by: Shannon
Thank you for your question. Unfortunately due to pharmacy regulations we can only accept a fax or scan directly from your veterinarian. We can contact your vet directly for the prescription, your vet may also contact us directly or you may mail in the original written prescription if you have one.
Answered by: Crystal PetMed Pro
Date published: 2017-07-31

Are these tables scored to be broke in half? 

Asked by: Shelby
Thank you for your question. The tablets have a score on them.
Answered by: leanniejo
Date published: 2017-07-26

can proin be given to a dog that is taking prednisone? 

Asked by: larry v
Do not give any other over-the-counter or prescription medications, including herbal products, during treatment with prednisone without first talking to your veterinarian. Many other medications can interact with prednisone resulting in side effects or altered effectiveness.
Answered by: Crystal PetMed Pro
Date published: 2017-11-10
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