|Kills Flea eggs and Larvae||Prevents Development|
|Kills and/or Repels Mosquitoes||*|
|Other Parasites Information||Kills chewing lice in dogs and puppies and controls mites that may cause sarcoptic mange.||Controls adult hookworms and removes and controls adult roundworms & whipworms|
(shampooing once a week can reduce effectiveness)
|Safe for pregnant or nursing Pets||Consult your veterinarian|
|How long does it take to work||Kills fleas and ticks with the same efficacy as Frontline Top Spot.||1 day||Begins to work Immediately, However, pre-existing flea populations may continue to develop and emerge.|
|Taste||Applied to Skin||Applied to Skin||Beef Flavor|
|Active Ingredient(s)||Fipronil||Amitraz||Milbemycin Oxime/Lufenuron|
|Rx Prescription Required(Details)|
|Dosage||Monthly||Effects last for up to 3 Months||Monthly|
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(Michael Dym, VMD)
|This product is a wonderful economic alternative for clients who have used the Frontline product. It contains the same exact main ingredient as Frontline, Fipronil, which has been probably the number one used flea and tick preventative ingredient by veterinarians over decades now. Not only does it kill fleas and many species of ticks that carry Lyme and other diseases, but also can help in controlling scabies mange mites, as well, in those cases. It certainly is a much cheaper alternative to Frontline or Advantage products. Some excellent advantages include it being waterproof, as well as being safe to use in pets as young as 8 weeks of age. There may be a rare skin irritation side effect at the site of application, but other reactions are even more rare. I have occasionally seen digestive upset with this product. I would also not use it in dogs with a history of chronic seizure disorders. Because of its long-term reliability and safety, I give this product an overall rating of a 4.5, with an ease of application of 4.5.||This is one of my favorite and most effective products in preventing tick infestations on dogs of all sizes, as well as preventing the tick born diseases such as Lyme disease, Rocky Mountain Spotted Fever, Ehlrichia and Anaplasmosis. When some of the topical products have failed in some patients, I have found this collar quite valuable in significantly cutting down on tick burdens in these dogs. The effects are long lasting for up to 3 months preventing ticks from even attaching to dogs, and thus cutting down on tick exposure to humans as well. The only problems in terms of efficacy I have even seen with this product is when animal guardians apply the collar too loosely to their pets, which can cut down on its efficacy against ticks.. In order for this collar to work effectively, it must be fitted snugly against the pet's neck, where one is just able to get two fingers under the collar. If the collar is applied too loosely I have occasionally seen pets ingest this collar, leading to serious systemic reactions. The only other downside in using this collar is if the pet spends a significant time swimming during the warmer months. The collar's efficacy is cut down significantly if it is submerged in water or exposed to drenching rains. However when properly fitted to a dog's neck, this is one of the most effective products in preventing tick infestations on the market.||Sentinel is a wonderful combination of the heartworm prevention pill interceptor and the flea control product program both in this one pill. Many clients enjoy the convenience of having such broad acting internal and external parasites in one pill, without having to worry about giving two separate medicines. Lufenuron, which is the main flea control ingredient, stops the flea life cycle in its track at the egg and larval stage, thus being like a birth control pill for fleas who get on our pets. Given that the main problem of fleas is how rapidly they reproduce, this pill literally stops escalating growth of flea populations, before they can become established in our homes, where most of the flea life cycle occurs. The main disadvantage to this product is that it does not kill or repel adult fleas, so in situations with already established heavy infestations, it is best combined with a great topical product like advantage or front line or with the oral adulticide flea pill Capstar for maximal effect. The only other rare disadvantage I see is the slight increase in reactions when two products are combined into one like this, but fortunately this is not common in clinical practice. With milbemycin for prevention of heartworms and controlling and treating most common intestinal worms, I overall highly recommend this versatile product.|
*Claim approved by the US Environmental Protection Agency; not by California E.P.A.
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