Gentizol is an antibiotic, antifungal, and anti-inflammatory ear ointment for dogs that treats canine acute and chronic otitis externa (inflammation or infection of the external auditory canal (EAC), the auricle, or both). This topical medication is a soothing ointment and is easy to apply. For otic (relating to the ear) use in dogs only. Gentizol comes in both a tube and bottle and requires a prescription from your veterinarian.
Gentizol ointment for dogs contains gentamicin sulfate, USP (United States Pharmacopeia), Betamethasone Valerate, USP and Clotrimazole, USP. Gentamicin Sulfate acts by inhibiting normal protein synthesis in susceptible microorganisms. It is active against the following organisms isolated from canine ears: Staphylococcus aureus, other Staphylococcus species, Pseudomonas aeruginosa, Proteus species, and Escherichia coli. Betamethasone provides anti-inflammatory and anti-pruritic activity in otitis externa. Clotrimazole prevents organisms from dividing and growing. Together, the ingredients provide antibiotic, antifungal and anti-inflammatory treatment by reducing discomfort, redness, swelling, exudate, and odor.
FOR OTIC USE IN DOGS ONLY. The use of gentamicin-betamethasone-clotrimazole ointment has been associated with deafness or partial hearing loss in a small number of sensitive dogs (e.g., geriatric). The hearing deficit is usually temporary. If hearing or vestibular dysfunction is noted during the course of treatment, discontinue use of gentamicin-betamethasone-clotrimazole ointment immediately and flush the ear canal thoroughly with a non-ototoxic solution. Corticosteroids administered to dogs, rabbits, and rodents during pregnancy have resulted in cleft palate in offspring. Other congenital anomalies including deformed forelegs, phocomelia (congenital deformity in limbs), and anasarca (widespread swelling of the skin) have been reported in offspring of dogs who received corticosteroids during pregnancy.
Gentamicin Sulfate, USP, Betamethasone Valerate, USP and Clotrimazole, USP
Gentizol is a prescription medicine for veterinary use in dogs. It's available in a 15 gm tube and a 25 gm bottle. Each gram of Gentizol ointment contains Gentamicin sulfate, USP equivalent to 3 mg gentamicin base; betamethasone valerate, USP equivalent to 1 mg betamethasone; and 10 mg clotrimazole, USP in a mineral oil-based system containing a plasticized hydrocarbon gel. Before administering Gentizol ointment to your dog, make sure the external ear is cleansed and dried, any excessive hair is clipped from the treatment area, and the eardrum is intact. Gentizol is for otic use in dogs only.
Consult with your veterinarian if your pet is breeding, pregnant or nursing.
Follow your veterinarian's exact instructions when administering Gentizol to your pet. The usual dose for dogs weighing under 30 lbs is 4 drops of the solution into the ear canal twice a day. For dogs weighing 30 lbs or more, the usual dose is 8 drops of the solution into the ear canal twice a day.
Side effects of Gentizol are related to the individual ingredients. Possible side effects of Gentamicin may include reversible and irreversible vestibular, cochlear, and renal toxicity. Betamethasone side effects can include weight loss, anorexia, polydipsia (excessive thirst), polyuria (excessive urination), vomiting, and diarrhea. If your pet experiences any side effects or any irritations of the skin, discontinue the medication and talk to your veterinarian.
Give the next dose of Gentizol as soon as you remember. If the next dose is almost due, skip the missed dose and apply the next one as directed. Don't give a double dose of Gentizol.
Contact your veterinarian if an overdose of Gentizol is suspected.
Do not use in dogs with perforated eardrums. Avoid use in dogs that are breeding, pregnant or lactating.
Talk to your veterinarian if your pet is taking any other medications.
Prior to use, the veterinarian will generally make sure the eardrum is intact and that the treatment continues for at least 7 days. Using this medication for the length of time it was prescribed is important to reduce the risk of antibiotic drug resistance or treatment failure.
|Under 30 lbs||Instill 4 drops into the ear canal.|
|30 lbs or more||Instill 8 drops into the ear canal.|
|Cats||Do not use!|
|Horses||Do not use!|
Store between 36-77 degrees Fahrenheit, and keep away from children, light, and moisture.
|Active Ingredients (per gram): Gentamicin sulfate, USP equivalent to 3 mg gentamicin base; betamethasone valerate, USP equivalent to 1 mg betamethasone; and 10 mg clotrimazole, USP in a mineral oil-based system containing a plasticized hydrocarbon gel.|