Advantage Multi

3.7 out of 5 Customer Rating
Advantage Multi is rated 4.3 out of 5 by 366.
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Starts $81.40 $56.98
Most orders ship the same day

Advantage Multi

3.7 out of 5 Customer Rating
Advantage Multi is rated 4.3 out of 5 by 366.
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Starts $81.40 $56.98
Most orders ship the same day
Dog
Cat

Reviews

Rated 5 out of 5 by from Good Product Our canine cardio vet specialist recommended this product to treat our new Great Pyrenees (mix) rescue who just arrived Heartworm and Hookworm positive. A safe product by all account. The only drawback is the application on a dog who has incredibly thick, long, healthy fur coat. It tends to draw the oil up to the surface, even when carefully applied on the skin.
Date published: 2020-06-07
Rated 5 out of 5 by from Good product for my babies!! Thanks 1800 petmeds.com !! The shipping was fast and the product is good for keep my babies healthy. I always recommended you guys.
Date published: 2020-06-01
Rated 5 out of 5 by from Treats multiple pests Was easy to apply. Cost less than another name brand.
Date published: 2020-05-30
Rated 5 out of 5 by from Advantage Multi and 1-800-PetMeds I highly recommend Advantage Multi. We've used it for years and it's the BEST. And, we're completely satisfied with 1-800-PetMeds. Great service. Thanks.
Date published: 2020-05-18
Rated 5 out of 5 by from Great prudouct we have tried different products none has worked as well as this! Would recommend to others!
Date published: 2020-05-14
Rated 4 out of 5 by from Never had a problem I love this monthly medication, it prevents against 7 different “bugs”. We take our dog hiking and walking multiple times a week and we have not ever had a problem (she is 4.5 yrs old and we have only ever used this product). I only gave it 4 stars bc it is a topical treatment so there are restrictions on how long it has to dry before she can get wet, and although it dries overnight, it leaves a residue for about a week. Still not enough to deter us from using. Great Product.
Date published: 2020-05-05
Rated 5 out of 5 by from Very easy to apply and LuLu thinks i'm petting her Having had dogs my whole life and living in many states always worried about dogs catching fleas and ticks. When our vet told us about your product it was a so easy and safe. Have used this on Pepi, Pepper, Copper, Chipper and now Lu Lu, don't worry we have owned more then one dog at a time and all from shelters and all live spoiled lives until age 15 to 18 when they cross the Rainbow bridge
Date published: 2020-05-04
Rated 4 out of 5 by from No Heartworm or Fleas for 4+ Years We chose this product over chewables because, after reading dozens of articles and speaking to our vet, we feel better about how the medicine is delivered. It's worked great for 4+ years. It would be a 5-star product if it hadn't DOUBLED in price by our third year, and if it also protected against ticks—which it does not (at all). It should be noted that it can be a messy/challenging application process for people who have long-haired dogs; I think a syringe type of delivery might work better there. Luckily for us we've a short-haired dog. Good product that we'll continue to use so long as it doesn't double again in price any time soon.
Date published: 2020-04-22
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Questions

I have 8 refills on a sticker on my box can I use it to get a refill?

Asked by: Resxwni01
Thank you for your question. If the prescription was last filled with us the refills would be valid and once you place an order we can fill the order without contacting your vet. If the refills indicated were from a previous order with your vet we would contact your vet directly or Pharmacy you purchased with to have the refills transferred to our Pharmacy. Please give us a call at 1-800-738-6337 so we may better assist you.
Answered by: Crystal RPTechnician
Date published: 2020-07-06

I’m from Mexico and I have a prescription for advantage multi from my Mexican Vet, can it work to keep my dog protected until we are able to fly back because of the Covid crisis?

Asked by: Moonkey
I'm so sorry, we can only accept a prescription authorization from a veterinarian licensed in the United States.
Answered by: Cherley Petmeds Pro
Date published: 2020-05-21

I'm trying to get the $20 rebate for the multi advantage I bought 4/6/20 at my vet's office. I can't find this on the web site.

Asked by: Susan
We do not deal with any rebates. Please contact customer service by calling 1-800-738-6337 or by emailing us at customerservice@1800petmeds.com so we can apply the amount as a merchandise credit for you.
Answered by: Cherley Petmeds Pro
Date published: 2020-04-15

I have one cat that is always chewing on himself and making bald spots everywhere, his belly his sides his tail like he's got little lice or something. And what kind of worms do they get from fleas chewing and eating them. How to get rid of them.

Asked by: David
You may want to consult with your veterinarian to rule out what is causing your furry baby to chew on himself. Your veterinarian can also prescribe the correct de wormer for you depending on the types of worms your furry baby contracted.
Answered by: Cherley Petmeds Pro
Date published: 2020-04-19

How soon after application may I bathe my dog?  May I bathe my dog after application?

Asked by: Wishedon
24 hours
Answered by: Katherine Ward
Date published: 2020-04-04

Do I have to have a prescription for advantage multi flea and tick drops ?

Asked by: Ann83
Yes
Answered by: Shari PetMed Pro
Date published: 2020-02-20

Is there an expiration date?

Asked by: v1j2j3
Advantage Multi normally has about a 2 to 3 year shelf life.
Answered by: Cherley Petmeds Pro
Date published: 2020-01-23

Do I need a prescription for ghis

Asked by: Scruffs
Yes, this does require a prescription.
Answered by: Kelly Paterson PharmD
Date published: 2020-01-11
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What is Advantage Multi?

Advantage Multi is an effective, convenient monthly topical solution for dogs and cats. It offers broad spectrum parasite protection in one easy application.

Advantage Multi for Dogs offers heartworm disease prevention that forgives if you forget. We all know how busy life can be and remembering to give heartworm protection on the same day every month can be a challenge. With Advantage Multi for Dogs, if you forget and go over 30 days between applications, just treat immediately and resume your monthly schedule. Advantage Multi for Dogs also kills adult fleas through contact, meaning they dont have to bite your dog to die. Additionally, the product treats flea infestations as well as 3 common intestinal parasites that infect and harm dogs (roundworms, hookworms, and whipworms). It also treats a very itchy skin mite called sarcoptes, which can infect people.

Advantage Multi for Cats kills adult fleas through contact meaning they don't have to bite and feed on your cat to die. It treats flea infestations as well as treats and controls the common occurring ear mite and intestinal parasites roundworms and hookworms. Advantage Multi for Cats prevents also heartworm disease, an often overlooked concern in cats. Additionally, Advantage Multi for Cats is also the first and only FDA-approved product to kill adult fleas, treat flea infestations, and prevent heartworm disease in ferrets.

NOTE: Advantage Multi does not protect against ticks. For additional 8 months of protection against fleas and ticks in dogs and cats, use the Seresto Collar.

For:

Dogs (7 weeks of age or older, weighing 3+ lbs), Cats (9 weeks of age or older, weighing 2+ lbs), Ferrets (weighing 2+ lbs)

Benefits:

  • Easy, once a month topical application
  • Heartworm prevention for dogs that fits your life style. If you forget and go over 30 days between applications, just apply immediately and resume your monthly treatment schedule.
  • Treats and controls circulating microfilaria found in heartworm positive dogs.
  • Kills adult fleas through contact. Fleas dont have to bite your dog or cat to die. Also treats fleas infestations.
  • Treats AND controls roundworms, hookworms, and whipworms in dogs and roundworms and hookworms in cats.
  • Treats AND controls infective ear mites in cats
  • Treats and controls sarcoptic mange in dogs
  • Advantage Multi for Cats is the only FDA-approved flea and heartworm disease prevention product for ferrets
  • Use the Seresto Collar (sold separately) for 8 months of additional protection against fleas, flea eggs, flea larvae, and ticks

How does Advantage Multi work?

Advantage Multi utilizes two effective ingredients, imidacloprid and moxidectin. Moxidectin kills baby heartworms that have been deposited in your dog or cat through the bite of a mosquito, preventing them from growing into adults, migrating to the heart, and causing disease. Moxidectin also kills common intestinal worms by intestinal worms by disrupting nerve transmission resulting in the paralysis and death. Imidacloprid kills fleas through contact. As fleas come in contact with your treated pet, imidacloprid is absorbed through the fleas skin where it acts on the nervous system resulting in spasm and death. Fleas do not need to bite and ingest it through the blood to die like oral treatments require.

Cautions:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become severe, consult a veterinarian immediately. Safety has not been established in breeding, pregnant, or lactating dogs. Not for human use. Keep out of the reach of children. Children should not come in contact with application sites for two (2) hours after application. Causes eye irritation. Harmful if swallowed. Do not get in eyes or on clothing. Avoid contact with skin. Exposure to the product has been reported to cause headache; dizziness; and redness, burning, tingling, or numbness of the skin. Wash hands thoroughly with soap and warm water after handling. If contact with eyes occurs, hold eyelids open and flush with copious amounts of water for 15 minutes. If eye irritation develops or persists, contact a physician. If swallowed, call a poison control center or physician immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by the poison control center or physician. People with known hypersensitivity to benzyl alcohol, imidacloprid or moxidectin should administer the product with caution. In case of allergic reaction, contact a physician. If contact with skin or clothing occurs, take off contaminated clothing. Wash skin immediately with plenty of soap and water. Call a poison control center or physician for treatment advice.

Brand Name:

Advantage Multi (Bayer)

Generic Name:

Imidacloprid, Moxidectin

What is the most important information I should know about Advantage Multi?

Advantage Multi for Dogs is available in the following concentrations; Advantage Multi 9 containing imidacloprid 40 mg and moxidectin 10 mg in 0.4 ml tubes for dogs 3-9 lbs, Advantage Multi 20 containing imidacloprid 100 mg and moxidectin 25 mg in 1 ml tubes for dogs 9.1 to 20 lbs, Advantage Multi 55 containing imidacloprid 250 mg and moxidectin 62.5 mg in 2.5 ml tubes for dogs 20.1-55 lbs, Advantage Multi 88 containing imidacloprid 400 mg and moxidectin 100 mg in 4 ml tubes for dogs 55.1 to 88 lbs, and Advantage Multi 110 containing imidacloprid 500 mg and moxidectin 125 mg in 5 ml tubes for dogs 88.1 to 110 lbs. For dogs over 110 lbs, use the appropriate combination of Advantage Multi for Dogs tubes. Advantage Multi for Cats is available in the following concentrations; Advantage Multi containing imidacloprid 23 mg and moxidectin 2.3 mg in 0.23 ml tubes for cats 2-5 lbs, Advantage Multi 9 containing imidacloprid 40 mg and moxidectin 4 mg in 0.4 ml tubes for cats 5.1 to 9 lbs, and Advantage Multi 18 containing imidacloprid 80 mg and moxidectin 8 mg in 0.8 ml tubes for cats 9.1 to 18 lbs. For cats over 18 lbs, use the appropriate combination. Children should not come in contact with the application site for two (2) hours after application.

What should I discuss with my veterinarian before applying Advantage Multi?

Tell your veterinarian if your pet is breeding, pregnant or lactating since safe use of this product in these cases has not been determined. Do not use in pets that are allergic to Advantage Multi or either of the individual ingredients, imidacloprid (Advantage II, K9 Advantix II) or moxidectin.

How should Advantage Multi be applied?

Advantage Multi is applied topically to the skin. It is not given by mouth. Follow the manufacturer's directions for application. Do not apply to irritated skin. Apply each dose once a month, every 30 days. If you do not understand the directions, or if you have difficulty applying the medication, contact your pharmacist or veterinarian. Store Advantage Multi at temperatures between 39 F and 77 F, avoiding excess heat or cold.

What are the potential side effects of Advantage Multi?

If any of the following serious side effects occur, stop using Advantage Multi and seek emergency veterinary medical attention: an allergic reaction (facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma). Contact your veterinarian if your pet shows scratching, rubbing, licking the application site, lethargy, decreased appetite, or hyperactivity. Contact your veterinarian if your pet shows lethargy and prolonged periods of sleep, behavioral changes including agitation, excessive grooming, hiding, pacing, etc., discomfort at the application site (rubbing, scratching, etc.), increased salivation within 1 hour of treatment, increased drinking, or coughing. A medicinal odor and residue at the application site may also be noticed. Ingestion of this product by pets may cause serious adverse reactions including depression, salivation, dilated pupils, incoordination, panting, and generalized muscle tremors. In avermectin sensitive pets, the signs may be more severe and may include coma and death. Hair may appear stiff, matted oily, or damp after application. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of Advantage Multi?

Apply the missed dose as soon as you remember. If it is almost time to apply the next dose, skip the missed dose and apply the next dose as directed. Do not apply 2 doses at once.

What happens if I overdose my pet on Advantage Multi?

Seek emergency veterinary medical treatment. Symptoms of overdose may include depression, increased salivation, tremors, or incoordination.

What should I avoid when applying Advantage Multi?

Always follow the dosage instructions provided by your veterinarian. Do not use in dogs under 7 weeks of age or less than 3 lbs. Do not use in cats under 9 weeks of age or less than 2 lbs. Do not use Advantage Multi for Cats in ferrets under 2 lbs. Do not use on pets that are sick, debilitated, or underweight. Do not use Advantage Multi for Dogs on a cat. Do not use Advantage Multi for Cats on a dog. Do not allow any pet to lick the application site for 30 minutes. Separation of treated pets may be necessary. Children should not come in contact with the application site for 30 minutes after application. Advantage Multi can cause eye irritation and be harmful if swallowed. Wash hands thoroughly with soap and water after handling.

What other drugs will affect Advantage Multi?

Talk to your veterinarian or pharmacist regarding any other medications, including vitamins and supplements, as well as other flea and tick products your pet is using.

Advantage Multi Directions:

  • Advantage Multi for Dogs and Advantage Multi for Cats are prescription medications used for the prevention of heartworm disease.
  • Advantage Multi for Dogs is also used in dogs for the treatment and control of flea infestation, hookworms, roundworms, whipworms, and sarcoptic mange.
  • Advantage Multi for Cats is also used in cats for the treatment and control of flea infestation, roundworms, hookworms, and ear mites.
  • Advantage Multi for Cats is also the first and only approved product to kill adult fleas, treat flea infestations, and prevent heartworm disease in ferrets.
  • Do not use Advantage Multi for Dogs on cats or ferrets.
  • Do not use Advantage Multi for Cats on dogs.
  • Do not administer this product orally.

Application instructions for Advantage Multi for Dogs:

  1. Remove one dose applicator tube from the package. As specified below, administer the entire contents of the Advantage Multi for Dogs tube that correctly corresponds with the body weight of your dog.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. Your dog should be standing for application. Part the hair on the back of your dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of your dog.

Application instructions for Advantage Multi for Cats:

  1. Remove one dose applicator tube from the package. Administer the entire contents of the Advantage Multi for Cats tube.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. FOR CATS: Part the hair on the back of your cat's neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube. FOR FERRETS: Part the hair on the back of your ferret's neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube. NOTE: Only Advantage Multi 9 should be used on ferrets.
Tip:

For the first 30 minutes after application, ensure that dogs and cats cannot lick the product from the application sites on themselves or other treated pets. Separate treated pets from one another and from other pets to reduce the risk of accidental ingestion. Wash hands with soap and water after handling. Do not let children touch the treated pet's skin for at least 30 minutes after applying the product. Do not get these products in your pet's mouth or eyes.

Advantage Multi Dosage for Dogs/Puppies: (7 weeks of age or older)

Dogs/Puppies: (7 weeks of age or older)
WeightDosage
3-9 lbsWhile your dog is standing, apply Advantage Multi 9 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
9.1-20 lbsWhile your dog is standing, apply Advantage Multi 20 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
20.1-55 lbsWhile your dog is standing, apply Advantage Multi 55 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
55.1-88 lbsWhile your dog is standing, apply Advantage Multi 88 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
88.1-110 lbs*While your dog is standing, apply Advantage Multi 110 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
Cats/Kittens: (9 weeks of age or older)
WeightDosage
2.1-5 lbs Apply Advantage Multi for Cats 2.1-5 lbs topically according to the above instructions. Apply each dose once every 30 days.
5.1-9 lbsApply Advantage Multi 9 for Cats topically according to the above instructions. Apply each dose once every 30 days.
9.1-18 lbs**Apply Advantage Multi 18 for Cats topically according to the above instructions. Apply each dose once every 30 days.
Ferrets:
WeightDosage
2-4.4 lbsApply Advantage Multi 9 for Cats topically according to the above instructions. Apply each dose once every 30 days.
Advantage Multi Dosage for Horses:
Horses
Do not use!

Storage:

Should be stored at room temperature between 39° F and 77° F, avoiding excess heat or cold.

*For dogs over 110 lbs use the appropriate combination.

**For cats over 18 lbs use the appropriate combination.

Advantage Multi Ingredients:

Advantage Multi 9 for Dogs 3-9 lbs:
Active IngredientsAmount
Imidacloprid40 mg
Moxidectin10 mg
Advantage Multi 20 for Dogs 9.1-20 lbs:
Active IngredientsAmount
Imidacloprid100 mg
Moxidectin25 mg
Advantage Multi 55 for Dogs 20.1-55 lbs:
Active IngredientsAmount
Imidacloprid250 mg
Moxidectin62.5 mg
Advantage Multi 88 for Dogs 55.1-88 lbs:
Active IngredientsAmount
Imidacloprid400 mg
Moxidectin100 mg
Advantage Multi 110 for Dogs 88.1-110 lbs:
Active IngredientsAmount
Imidacloprid500 mg
Moxidectin125 mg
Advantage Multi for Cats 2.1-5 lbs:
Active IngredientsAmount
Imidacloprid 23 mg
Moxidectin 2.3 mg
Advantage Multi 9 for Cats 5.1-9 lbs:
Active IngredientsAmount
Imidacloprid40 mg
Moxidectin4 mg
Advantage Multi 18 for Cats 9.1-18 lbs:
Active IngredientsAmount
Imidacloprid80 mg
Moxidectin8 mg

What is Advantage Multi?

Advantage Multi is an effective, convenient monthly topical solution for dogs and cats. It offers broad spectrum parasite protection in one easy application.

Advantage Multi for Dogs offers heartworm disease prevention that forgives if you forget. We all know how busy life can be and remembering to give heartworm protection on the same day every month can be a challenge. With Advantage Multi for Dogs, if you forget and go over 30 days between applications, just treat immediately and resume your monthly schedule. Advantage Multi for Dogs also kills adult fleas through contact, meaning they dont have to bite your dog to die. Additionally, the product treats flea infestations as well as 3 common intestinal parasites that infect and harm dogs (roundworms, hookworms, and whipworms). It also treats a very itchy skin mite called sarcoptes, which can infect people.

Advantage Multi for Cats kills adult fleas through contact meaning they don't have to bite and feed on your cat to die. It treats flea infestations as well as treats and controls the common occurring ear mite and intestinal parasites roundworms and hookworms. Advantage Multi for Cats prevents also heartworm disease, an often overlooked concern in cats. Additionally, Advantage Multi for Cats is also the first and only FDA-approved product to kill adult fleas, treat flea infestations, and prevent heartworm disease in ferrets.

NOTE: Advantage Multi does not protect against ticks. For additional 8 months of protection against fleas and ticks in dogs and cats, use the Seresto Collar.

For:

Dogs (7 weeks of age or older, weighing 3+ lbs), Cats (9 weeks of age or older, weighing 2+ lbs), Ferrets (weighing 2+ lbs)

Benefits:

  • Easy, once a month topical application
  • Heartworm prevention for dogs that fits your life style. If you forget and go over 30 days between applications, just apply immediately and resume your monthly treatment schedule.
  • Treats and controls circulating microfilaria found in heartworm positive dogs.
  • Kills adult fleas through contact. Fleas dont have to bite your dog or cat to die. Also treats fleas infestations.
  • Treats AND controls roundworms, hookworms, and whipworms in dogs and roundworms and hookworms in cats.
  • Treats AND controls infective ear mites in cats
  • Treats and controls sarcoptic mange in dogs
  • Advantage Multi for Cats is the only FDA-approved flea and heartworm disease prevention product for ferrets
  • Use the Seresto Collar (sold separately) for 8 months of additional protection against fleas, flea eggs, flea larvae, and ticks

How does Advantage Multi work?

Advantage Multi utilizes two effective ingredients, imidacloprid and moxidectin. Moxidectin kills baby heartworms that have been deposited in your dog or cat through the bite of a mosquito, preventing them from growing into adults, migrating to the heart, and causing disease. Moxidectin also kills common intestinal worms by intestinal worms by disrupting nerve transmission resulting in the paralysis and death. Imidacloprid kills fleas through contact. As fleas come in contact with your treated pet, imidacloprid is absorbed through the fleas skin where it acts on the nervous system resulting in spasm and death. Fleas do not need to bite and ingest it through the blood to die like oral treatments require.

Cautions:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become severe, consult a veterinarian immediately. Safety has not been established in breeding, pregnant, or lactating dogs. Not for human use. Keep out of the reach of children. Children should not come in contact with application sites for two (2) hours after application. Causes eye irritation. Harmful if swallowed. Do not get in eyes or on clothing. Avoid contact with skin. Exposure to the product has been reported to cause headache; dizziness; and redness, burning, tingling, or numbness of the skin. Wash hands thoroughly with soap and warm water after handling. If contact with eyes occurs, hold eyelids open and flush with copious amounts of water for 15 minutes. If eye irritation develops or persists, contact a physician. If swallowed, call a poison control center or physician immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by the poison control center or physician. People with known hypersensitivity to benzyl alcohol, imidacloprid or moxidectin should administer the product with caution. In case of allergic reaction, contact a physician. If contact with skin or clothing occurs, take off contaminated clothing. Wash skin immediately with plenty of soap and water. Call a poison control center or physician for treatment advice.

Brand Name:

Advantage Multi (Bayer)

Generic Name:

Imidacloprid, Moxidectin

What is the most important information I should know about Advantage Multi?

Advantage Multi for Dogs is available in the following concentrations; Advantage Multi 9 containing imidacloprid 40 mg and moxidectin 10 mg in 0.4 ml tubes for dogs 3-9 lbs, Advantage Multi 20 containing imidacloprid 100 mg and moxidectin 25 mg in 1 ml tubes for dogs 9.1 to 20 lbs, Advantage Multi 55 containing imidacloprid 250 mg and moxidectin 62.5 mg in 2.5 ml tubes for dogs 20.1-55 lbs, Advantage Multi 88 containing imidacloprid 400 mg and moxidectin 100 mg in 4 ml tubes for dogs 55.1 to 88 lbs, and Advantage Multi 110 containing imidacloprid 500 mg and moxidectin 125 mg in 5 ml tubes for dogs 88.1 to 110 lbs. For dogs over 110 lbs, use the appropriate combination of Advantage Multi for Dogs tubes. Advantage Multi for Cats is available in the following concentrations; Advantage Multi containing imidacloprid 23 mg and moxidectin 2.3 mg in 0.23 ml tubes for cats 2-5 lbs, Advantage Multi 9 containing imidacloprid 40 mg and moxidectin 4 mg in 0.4 ml tubes for cats 5.1 to 9 lbs, and Advantage Multi 18 containing imidacloprid 80 mg and moxidectin 8 mg in 0.8 ml tubes for cats 9.1 to 18 lbs. For cats over 18 lbs, use the appropriate combination. Children should not come in contact with the application site for two (2) hours after application.

What should I discuss with my veterinarian before applying Advantage Multi?

Tell your veterinarian if your pet is breeding, pregnant or lactating since safe use of this product in these cases has not been determined. Do not use in pets that are allergic to Advantage Multi or either of the individual ingredients, imidacloprid (Advantage II, K9 Advantix II) or moxidectin.

How should Advantage Multi be applied?

Advantage Multi is applied topically to the skin. It is not given by mouth. Follow the manufacturer's directions for application. Do not apply to irritated skin. Apply each dose once a month, every 30 days. If you do not understand the directions, or if you have difficulty applying the medication, contact your pharmacist or veterinarian. Store Advantage Multi at temperatures between 39 F and 77 F, avoiding excess heat or cold.

What are the potential side effects of Advantage Multi?

If any of the following serious side effects occur, stop using Advantage Multi and seek emergency veterinary medical attention: an allergic reaction (facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma). Contact your veterinarian if your pet shows scratching, rubbing, licking the application site, lethargy, decreased appetite, or hyperactivity. Contact your veterinarian if your pet shows lethargy and prolonged periods of sleep, behavioral changes including agitation, excessive grooming, hiding, pacing, etc., discomfort at the application site (rubbing, scratching, etc.), increased salivation within 1 hour of treatment, increased drinking, or coughing. A medicinal odor and residue at the application site may also be noticed. Ingestion of this product by pets may cause serious adverse reactions including depression, salivation, dilated pupils, incoordination, panting, and generalized muscle tremors. In avermectin sensitive pets, the signs may be more severe and may include coma and death. Hair may appear stiff, matted oily, or damp after application. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of Advantage Multi?

Apply the missed dose as soon as you remember. If it is almost time to apply the next dose, skip the missed dose and apply the next dose as directed. Do not apply 2 doses at once.

What happens if I overdose my pet on Advantage Multi?

Seek emergency veterinary medical treatment. Symptoms of overdose may include depression, increased salivation, tremors, or incoordination.

What should I avoid when applying Advantage Multi?

Always follow the dosage instructions provided by your veterinarian. Do not use in dogs under 7 weeks of age or less than 3 lbs. Do not use in cats under 9 weeks of age or less than 2 lbs. Do not use Advantage Multi for Cats in ferrets under 2 lbs. Do not use on pets that are sick, debilitated, or underweight. Do not use Advantage Multi for Dogs on a cat. Do not use Advantage Multi for Cats on a dog. Do not allow any pet to lick the application site for 30 minutes. Separation of treated pets may be necessary. Children should not come in contact with the application site for 30 minutes after application. Advantage Multi can cause eye irritation and be harmful if swallowed. Wash hands thoroughly with soap and water after handling.

What other drugs will affect Advantage Multi?

Talk to your veterinarian or pharmacist regarding any other medications, including vitamins and supplements, as well as other flea and tick products your pet is using.

Advantage Multi Directions:

  • Advantage Multi for Dogs and Advantage Multi for Cats are prescription medications used for the prevention of heartworm disease.
  • Advantage Multi for Dogs is also used in dogs for the treatment and control of flea infestation, hookworms, roundworms, whipworms, and sarcoptic mange.
  • Advantage Multi for Cats is also used in cats for the treatment and control of flea infestation, roundworms, hookworms, and ear mites.
  • Advantage Multi for Cats is also the first and only approved product to kill adult fleas, treat flea infestations, and prevent heartworm disease in ferrets.
  • Do not use Advantage Multi for Dogs on cats or ferrets.
  • Do not use Advantage Multi for Cats on dogs.
  • Do not administer this product orally.

Application instructions for Advantage Multi for Dogs:

  1. Remove one dose applicator tube from the package. As specified below, administer the entire contents of the Advantage Multi for Dogs tube that correctly corresponds with the body weight of your dog.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. Your dog should be standing for application. Part the hair on the back of your dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of your dog.

Application instructions for Advantage Multi for Cats:

  1. Remove one dose applicator tube from the package. Administer the entire contents of the Advantage Multi for Cats tube.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. FOR CATS: Part the hair on the back of your cat's neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube. FOR FERRETS: Part the hair on the back of your ferret's neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube. NOTE: Only Advantage Multi 9 should be used on ferrets.
Tip:

For the first 30 minutes after application, ensure that dogs and cats cannot lick the product from the application sites on themselves or other treated pets. Separate treated pets from one another and from other pets to reduce the risk of accidental ingestion. Wash hands with soap and water after handling. Do not let children touch the treated pet's skin for at least 30 minutes after applying the product. Do not get these products in your pet's mouth or eyes.

Advantage Multi Dosage for Dogs/Puppies: (7 weeks of age or older)

Dogs/Puppies: (7 weeks of age or older)
WeightDosage
3-9 lbsWhile your dog is standing, apply Advantage Multi 9 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
9.1-20 lbsWhile your dog is standing, apply Advantage Multi 20 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
20.1-55 lbsWhile your dog is standing, apply Advantage Multi 55 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
55.1-88 lbsWhile your dog is standing, apply Advantage Multi 88 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
88.1-110 lbs*While your dog is standing, apply Advantage Multi 110 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
Cats/Kittens: (9 weeks of age or older)
WeightDosage
2.1-5 lbs Apply Advantage Multi for Cats 2.1-5 lbs topically according to the above instructions. Apply each dose once every 30 days.
5.1-9 lbsApply Advantage Multi 9 for Cats topically according to the above instructions. Apply each dose once every 30 days.
9.1-18 lbs**Apply Advantage Multi 18 for Cats topically according to the above instructions. Apply each dose once every 30 days.
Ferrets:
WeightDosage
2-4.4 lbsApply Advantage Multi 9 for Cats topically according to the above instructions. Apply each dose once every 30 days.
Advantage Multi Dosage for Horses:
Horses
Do not use!

Storage:

Should be stored at room temperature between 39° F and 77° F, avoiding excess heat or cold.

*For dogs over 110 lbs use the appropriate combination.

**For cats over 18 lbs use the appropriate combination.

Advantage Multi Ingredients:

Advantage Multi 9 for Dogs 3-9 lbs:
Active IngredientsAmount
Imidacloprid40 mg
Moxidectin10 mg
Advantage Multi 20 for Dogs 9.1-20 lbs:
Active IngredientsAmount
Imidacloprid100 mg
Moxidectin25 mg
Advantage Multi 55 for Dogs 20.1-55 lbs:
Active IngredientsAmount
Imidacloprid250 mg
Moxidectin62.5 mg
Advantage Multi 88 for Dogs 55.1-88 lbs:
Active IngredientsAmount
Imidacloprid400 mg
Moxidectin100 mg
Advantage Multi 110 for Dogs 88.1-110 lbs:
Active IngredientsAmount
Imidacloprid500 mg
Moxidectin125 mg
Advantage Multi for Cats 2.1-5 lbs:
Active IngredientsAmount
Imidacloprid 23 mg
Moxidectin 2.3 mg
Advantage Multi 9 for Cats 5.1-9 lbs:
Active IngredientsAmount
Imidacloprid40 mg
Moxidectin4 mg
Advantage Multi 18 for Cats 9.1-18 lbs:
Active IngredientsAmount
Imidacloprid80 mg
Moxidectin8 mg