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Trifexis
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
What is Trifexis?
Trifexis is a chewable tablet that kills fleas and prevents infestations, protects against heartworms, and treats and controls adult hookworm, roundworm, and whipworm infections. Trifexis requires a prescription from your veterinarian.
For:
Dogs (8 weeks of age and older and weighing at least 5 lbs)
Benefits:
- Begins killing biting fleas within 30 minutes
- Kills fleas before they can lay eggs
- Prevents heartworm disease
- Treats and controls roundworms, hookworms, and whipworms
- Artificial beef flavor made from pork liver and hydrolyzed soy
- Easy-to-administer chewable tablet
How it Works:
Spinosad, an active ingredient in Trifexis, starts to work within 30 minutes to kill fleas and has been proven to kill 100% of all biting fleas within 4 hours. Trifexis also kills flea eggs before they can mature, which helps to end the flea life cycle. Trifexis prevents heartworm disease by killing microfilariae and larvae from maturing into adult heartworms.
Cautions:
Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis chewable tablets. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy. Puppies less than 14 weeks of age may experience a higher rate of vomiting. Consult your veterinarian for pregnant or lactating dogs.
Brand Name:
Trifexis (Elanco Animal Health)
Generic Name:
Spinosad and Milbemycin oxime
What is the most important information I should know about Trifexis:
Trifexis is a prescription medication FDA approved for use in dogs 8 weeks of age or older and 5 lbs of body weight or more. Trifexis contains spinosad and milbemycin oxime and is indicated for the prevention of heartworm disease. Trifexis kills fleas and is indicated for the prevention and treatment of flea infestations, and the treatment and control of adult hookworm, adult roundworm, and adult whipworm infections. Trifexis is available in a pink box for dogs 5 to 10 lbs (140mg/2.3mg)), Orange box for dogs 10.1 to 20 lbs (270mg/4.5mg), Green box for dogs 20.1 to 40 lbs (560mg/9.3mg), Blue box for dogs 40.1 to 60 lbs (810mg/13.5mg), and Brown box for dogs 60.1 to 120 lbs (1620mg/27mg). For dogs over 120 lbs give the appropriate combination of tablets.
What is Trifexis:
Trifexis is a chewable, beef flavored tablet that is made out of pork liver and hydrolyzed soy and given to your dog once month to prevent heartworm, to prevent and treat flea infestations, and to treat and control adult hookworm, roundworm, and whipworm infections. Trifexis chewable tablets are for monthly use in dogs and puppies 8 weeks of age and older and 5 lbs of body weight or more.
What should I discuss with my veterinarian before giving Trifexis to my pet:
Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog has a history of seizures (epilepsy).
How should this medication be given:
Give Trifexis chewable tablets with food. Give Trifexis chewable tablets once a month. Trifexis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose the pet with another full dose. Store Trifexis at room temperature (68-77° F). Consult your veterinarian for pregnant or lactating dogs.
What happens if I miss a dose:
Give the missed dose with food as soon as you remember and resume a monthly dosing schedule.
What happens if I overdose the pet:
Overdose of this medication is unlikely. However, if an overdose is suspected, contact your veterinarian or veterinary emergency room. Symptoms of overdose that may occur include vomiting.
What should I avoid while giving Trifexis:
Your pet may maintain normal activities and interactions while being given Trifexis. The safe use of Trifexis chewable tablets in male dogs intended for breeding has not been established.
What are the possible side effects of Trifexis:
Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Trifexis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to the pet.
What other drugs will affect Trifexis:
Talk to your veterinarian before giving any prescription or over the counter medications.
Where can I get more information:
Your pharmacist has additional information about Trifexis written for health professionals that you may read.
Directions:
- Please view the chart below for the correct dosage of Trifexis for your dog.
Tip:
Trifexis does not protect against ticks. To help control ticks, try the Preventic Tick Collar.
Dosage:
Dogs (Over 8 weeks of age)
Weight
Dosage
5 - 10 lbs
Give one tablet (Pink label box)
10.1 - 20 lbs
Give one tablet (Orange label box)
20.1 - 40 lbs
Give one tablet (Green label box)
40.1 - 60 lbs
Give one tablet (Blue label box)
60.1 - 120 lbs
Give one tablet (Brown label box)
Over 120 lbs
Administer the appropriate combination of tablets
Cats:
Do not use!
Horses:
Do not use!
Storage:
Should be stored at room temperature. Keep away from pets and children.
Trifexis for Dogs 5 to 10 lbs:
Active Ingredients per tablet
Amount
Spinosad
140 mg
Milbemycin oxime
2.3 mg
Trifexis for Dogs 10.1 to 20 lbs:
Active Ingredients per tablet
Amount
Spinosad
270 mg
Milbemycin oxime
4.5 mg
Trifexis for Dogs 20.1 to 40 lbs:
Active Ingredients per tablet
Amount
Spinosad
560 mg
Milbemycin oxime
9.3 mg
Trifexis for Dogs 40.1 to 60 lbs:
Active Ingredients per tablet
Amount
Spinosad
810 mg
Milbemycin oxime
13.5 mg
Trifexis for Dogs 60.1 to 120 lbs:
Active Ingredients per tablet
Amount
Spinosad
1620 mg
Milbemycin oxime
27 mg
Trifexis is rated
out of
5 by
440.
Rated 5 out of
5 by
statseeker from
Does what it's supposed to
I've had 3 dogs on Trifexis and so far we haven't had any fleas on them after treatment. Even if 1 or 2 manage to stay on the dogs, they move slow, sickly and eventually die. I love it. The dogs aren't affected poorly by it. All in all 3 happy tails.
Date published: 2016-03-22
Rated 5 out of
5 by
Lady from
Fills the Need
We have been using Trifexis since we got our dog three years ago. She responds well to it and we've had not fleas, ticks, heartworms, etc. She is healthy and satisfied. She does not resist my giving her one pill on the 1st of each month. Our vet in Texas got us started and I requested the same product from our "new" vet in Bloomington, IN. Consult your own vet and read up on its benefits at the Trifexis web site.
Date published: 2016-03-18
Rated 5 out of
5 by
Jball from
Only one on the market that works on our yorkie
Date published: 2016-03-16
Rated 1 out of
5 by
selena from
never buy this heart worm pills for my dogs
My dog have been itching ,scrating and biting her body all day long since she took this pills. She got a bold spot and I took her to see the vet and gave her test. She got a positive heart worm disease. She shouldn't get a positive result . I can not believe it !
Date published: 2016-03-15
Rated 5 out of
5 by
J P P from
Work's as advertised.
Gretchen our GSD has been on trifexis for 18 months. Gretchen doesn't know what a flea is and is negative for all parasites, heart worm etc.
Date published: 2016-03-11
Rated 5 out of
5 by
Tootsie from
Works and super easy!!
This stuff works great. We have been giving it to our Australian Shepherd for years now and no fleas. You should give them this drug on a full stomach.
Date published: 2016-03-05
Rated 5 out of
5 by
Nuschler from
Trifexis is a superb drug!
I have been using Trifexis for 15 years for my service dog and for our military working dogs. These military dogs can parachute out of helicopters for special operations. NO seizures and NO heart worm, round worms, hook worms or fleas. Our working dogs MUST be healthy. We work with the Auburn University Vet college and they agree that Trifexis is the best at preventing these parasites. All drugs can cause side effects in humans and dogs. But the benefit of preventing these possible deadly parasites vs a few dogs developing seizures is overwhelming. And a seizure does NOT mean your dog will die. It just means you need to change meds. These drugs are potent--they MUST be potent to kill these awful parasites!
Keep your dogs safe. Auburn U has done extensive work with Trifexis and there is no better prevention drug! Keep your dogs healthy. Use Trifexis!
Date published: 2016-02-24
Rated 4 out of
5 by
AryasOwner from
Does the Job
So two years of using this product, I like the results because my dog has had no problems at all. The only issue I have is the product (Pill), my pet will not take willingly. I would say only the first time she took it she did so on her own. After that she would refuse to consume the pill. After that I had to physically force it down her throat and if that was too difficult to do I would attempt other methods. I have used Cheese, Peanut Butter and ground up the pill and mixed it into a small amount of ice cream.
I will be looking for a new product, hoping for the same results except the process of taking the pill.
Date published: 2016-02-21
I still have some but they are over a year old can I still use them
If your dog has not missed any monthly treatments, check the expiration date on your Trifexis to see if it is still good. Most product has an expiration date that is over a year from when our hospital purchases it from the manufacturer.
Date published: 2016-03-18
I have a 16 week old lab puppy who weighs 30 lbs. what size Trifkexus should I buy as he will go past the 40 lb within two months?
Please check with your Pet's Veterinarian as to what the proper medication and dosage should be based on your pets age and size.
Date published: 2016-03-12
How soon can I give my yorkie trifexis?
Trifexis is safe to administer in pets 8 weeks or older who weigh at least 5 pounds.
Date published: 2016-03-08
does this product also protect against ticks?
Trifexis does not provide protection against ticks.
Date published: 2016-03-22
I have had my local Vet prescribe Trifexis and now he wants $140 refill. Can I scan my last scrip and send it to you for filling?
We will contact your pet's clinic for the approval once you order Trifexis. We can only accept original prescription by mail or the vet may scan or email us the approval. We contact the vet for you once you place the order and most veterinarians respond within 24 hours and your pets prescription will ship out.
Date published: 2016-03-08
Will my dog need to be tested for heartworms yearly while on trifexis?
Since Trifexis is a prescription medication, your vet will need to perform a yearly exam and any required tests, including a heartworm test, depending upon your state's requirements. In Florida, an annual heartworm test is required.
Date published: 2016-03-22
is it ok to cut the trifexis pill in half or to quarter it but give
but give the full pill cut in half or quartered?
Some dogs tolerate the medication a little better if given it halved or quartered so long as the entire pill is given within an hour or two. Letting the pill "air out" for a couple of hours has been known to improve the palatability of the tablet for those very picky dogs.
Date published: 2016-01-09
How many pills total will I be receiving?
Is it 6 packs of 6 pills or 6 pills total?
A 6-pack always means one package of 6 tablets.
Date published: 2016-01-09
