Infected dogs may be lethargic, have a poor/loss of appetite, or a fever (103° - 105° F). Lameness, shifting from one joint to another, fatigue, aggression, confusion, overeating, and seizures are all signs of Lyme disease in your dog. Like cats, some dogs can be infected but not exhibit any noticeable symptoms.
Frontline Plus is effective in preventing Lyme Disease by warding off ticks, but it does not treat a dog infected with Lyme Disease. If you suspect your pet has Lyme disease, you should bring your pet to a veterinarian for medical attention.