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K9 Advantix II

Starts $60.61 $43.64 
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is K9 Advantix II?

K9 Advantix II is a monthly preventative for dogs that offers comprehensive protection against ticks, fleas, mosquitoes, biting flies, and chewing lice. K9 Advantix II is a top veterinarian-recommended brand because it repels and kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks). K9 Advantix II kills 98-100 percent of fleas within 12 hours and continues working for one month to prevent infestations. Fleas and ticks are killed on contact with a treated dog, which means that fleas don't have to bite and ticks don't have to attach to die. This helps prevent transmission of flea-borne and tick-borne diseases such as tapeworms, Lyme disease, tick paralysis, ehrlichia, and Rocky Mountain spotted fever. Killing fleas before they bite may also help prevent skin allergies caused by flea saliva. As well, K9 Advantix II repels mosquitoes before they bite, which may help prevent transmission of heartworms. K9 Advantix II protects your pet before parasites have a chance to bite, not after.

For:

Dogs and Puppies (only over 4 lbs and 7 weeks of age or older)

Benefits:
  • Repels and kills disease-carrying fleas, ticks, and mosquitoes before they bite
  • Kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks)
  • Kills 98-100 percent of adult fleas within 12 hours
  • Ends flea life cycle by preventing flea offspring (eggs, pupae, and larvae) from maturing into adult fleas
  • Repels biting flies and kills chewing lice
  • Provides one month of protection against ticks, fleas, mosquitoes, biting flies
  • Waterproof - continues working even after your dog becomes wet
How it works:

K9 Advantix II combines imidacloprid and permethrin to repel and kill fleas, ticks, and mosquitoes. Both ingredients work on contact, attacking parasite nerve cells at different sites. Together these ingredients overwhelm the nervous system killing the parasite. Pyriproxyfen is an insect growth regulator. K9 Advantix II topical solution also repels biting flies and kills lice.

Cautions:

DO NOT USE ON CATS. Cats cannot metabolize the ingredients used in this product. Cats must be separated from dogs during treatment. Do not allow your cat to come in contact with a treated dog for 24 hours. Some small and medium dogs may have an adverse skin reaction.

Brand Name:

K9 Advantix II (Bayer)

Active Ingredient(s):

Imidacloprid (8.8%), Permethrin (44.0%), Pyriproxyfen (0.44%), Other ingredients (46.76%)

What is this product used for:

K9 Advantix II is for use on dogs and puppies 4 lbs or more and 7 weeks of age or older only. It is used for the topical prevention and treatment of ticks, fleas, mosquitoes, biting flies, and chewing lice on dogs. Repels and kills ticks including deer ticks (the major carrier of Lyme disease), American dog ticks, Brown dog ticks and lone star ticks. K9 Advantix II repels and kills all life stages of fleas, repels and kills mosquitoes, kills chewing lice, and repels biting flies.

Availability:

K9 Advantix II is a non-prescription (OTC) product available as 0.014 fl oz (0.4 ml) applicators for dogs 4-10 lbs (Green), 0.034 fl oz (1.0 ml) applicators for dogs 11-20 lbs (Teal), 0.084 fl oz (2.5 ml) applicators for dogs 21-55 lbs (Red), and 0.135 fl oz (4.0 ml) applicators for dogs over 55 lbs (Blue).

How this product should be used:

For use only on dogs. Do not use on cats or on other animals. Have the dog standing for easy application. Part the hair on the dog's back, between the shoulder blades, until the skin is visible. For dogs up to 20 lbs, apply the entire contents of the applicator tube to 2 or 3 spots on the top of the back from the shoulder to the base of the tail. For dogs 21 lbs and over, apply the entire contents of the applicator tube to 4 or 6 spots on the top of the back from the shoulder to the base of the tail. If the household has cats or other animals, separate from the treated dog for 24 hours.

What are the side effects:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. A small percentage of dogs have had adverse reactions to K9 Advantix II. A sensation of burning, tingling, itching, redness or numbness of the skin may occur after topical application. This sensation usually begins 1-2 hours after application. In addition, reactions have occurred in cats that have been exposed to a medicated dog. That is why it is important to separate your cat from a medicated dog for 24 hours. Bayer, the manufacturer of K9 Advantix II, indicates that some of these symptoms will dissipate within 48 hours; however, if your pet is experiencing adverse reactions, please complete the following steps:

  • Stop applying the medication
  • Wash your dog with a detergent based soap (Dawn or Palmolive dish detergents work best). Do not scrub the affected area, as this may cause more skin irritation. Please note: This process is applicable for both dogs and cats.
  • Call your veterinarian
  • Call Bayer Emergency Support Line at 1-800-422-9874. Let Bayer know your dog is having an adverse reaction to K9 Advantix by calling 1-800-422-9874. This line is staffed 24 hours a day, 7 days a week.
What special precautions are there:

This product is for external use only on dogs and puppies 4 lbs or more and 7 weeks or older. Consult a veterinarian before using on medicated animals and debilitated, aged, pregnant or nursing animals. Do not get this product in dog's eyes or mouth. Do not use this product on animals other than dogs. In households with cats, separate the treated dog for about 24 hours. Due to their unique physiology and inability to metabolize certain compounds, this product must not be used on cats. If applied to a cat, or ingested by a cat which actively grooms a recently treated dog, this product may have serious harmful effects. If this occurs, contact your veterinarian immediately. It is important to apply this product no more than once a month and to use the correct strength for the weight of the dog. This product is harmful to humans if swallowed. Call a physician or poison control center for advice. Have patient sip water. Do not induce vomiting unless advised to and the patient is conscious. This product can cause eye irritation. Flush eyes with plenty of water. Call a physician if irritation persists. Avoid contact with skin, eyes or clothing. Wash thoroughly with soap and water after handling.

In the event of overdose:

Contact your veterinarian or veterinary emergency room.

How should I store this product:

Store this product in a cool, dry place. Do not refrigerate. Store in the original container only. Do not reuse original container. If the container is empty place in trash or offer for recycling if available. If the container is partially filled, call for disposal instructions. Never place unused product down any indoor or outdoor drain.

How to Use
Directions:
  • Use only on dogs over 4 lbs and over 7 weeks of age. Do not use on cats or on other animals.
  • Your dog should be standing for easy application.
  • The entire contents of K9 Advantix II tube should be applied evenly to the top of the back from the shoulder to the base of the tail.
  • At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin.
  • Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of your dog.
  • For dogs up to 20 lbs, apply the entire contents of the applicator tube to 2 or 3 spots on the top of the back from the shoulder to the base of the tail.
  • For dogs 21 lbs and over, apply the entire contents of the applicator tube to 4 or 6 spots on the top of the back from the shoulder to the base of the tail.
  • Use only one applicator per treatment.
Tip:

In households with cats, separate the treated dog for 24 hours until the product is thoroughly dry. Visit K9 Advantix II Adverse Reactions if your pet has been experiencing adverse reactions to K9 Advantix II.

Dosage:
Dogs/Puppies:(7 weeks of age and older)
Weight
Dosage
1-3 lbs
Do not use.
4-10 lbs
Apply contents of 1 applicator once a month (Green Box)
11-20 lbs
Apply contents of 1 applicator once a month (Teal Box)
21-55 lbs
Apply contents of 1 applicator once a month (Red Box)
Over 55 lbs
Apply contents of 1 applicator once a month (Blue Box)
Cats:
Do not use!
Horses:
Do not use!
Storage:

Should be stored in a cool dry place. Do not refrigerate.

Ingredients
K9 Advantix II for Dogs 4-10 lbs (Small Dog - Green Box) (0.4 mL):
Active Ingredients (per applicator tube)
% By Weight
Imidacloprid
8.80%
Permethrin*
44.0%
Pyriproxyfen
0.44%
Other Ingredients (not specified)
46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 11-20 lbs (Medium Dog - Teal Box) (1.0 mL):
Active Ingredients (per applicator tube)
% By Weight
Imidacloprid
8.80%
Permethrin*
44.0%
Pyriproxyfen
0.44%
Other Ingredients (not specified)
46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 21-55 lbs (Large Dog - Red Box) (2.5 mL):
Active Ingredients (per applicator tube)
% By Weight
Imidacloprid
8.80%
Permethrin*
44.0%
Pyriproxyfen
0.44%
Other Ingredients (not specified)
46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs over 55 lbs (Extra Large Dog - Blue Box) (4.0 mL):
Active Ingredients (per applicator tube)
% By Weight
Imidacloprid
8.80%
Permethrin*
44.0%
Pyriproxyfen
0.44%
Other Ingredients (not specified)
46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
Customer Reviews
K9 Advantix II is rated 3.707021092169893 out of 5 by 3,461.
Rated 1 out of 5 by from Did not work for my pup After days of research, I settled on K9 Advantix II because of the (mostly) good reviews and reasonable price. Unfortunately, this topical treatment did not work for my dog. I purchased it because it said it repels AND kills fleas but it did neither, even after a second dose. I will be putting her on oral medication only in the future, as topical does not seem to be effective. I contacted customer service, however, and they were very understanding.
Date published: 2016-08-22
Rated 1 out of 5 by from Did not work My dogs were not infested and this product couldnt kill the few fleas they had. Frontline will be getting my money next time.
Date published: 2016-08-22
Rated 1 out of 5 by from Don't buy I've used this product on and off for the last two-three years. It has never worked for my dog.(the way the package claims). I've followed the directions on the package as well as asked my vet to show me how to properly use it. The instructions say to put product on multiple spots along the back but my vet told me to squeeze out the entire liquid on one spot. Neither method worked. I will NEVER buy this again. I might as blend my money and sprinkle that on the dog. To be fair my dog and I spend several hours per day outside. If you live in a heavily infested flea/tick area try an RX oral flea/tick. I tried an oral med and it was the first time my dog was flea/tick free for a full month. The oral med may be more expensive but it's worth the peace of mind.
Date published: 2016-08-21
Rated 5 out of 5 by from Only one that works! We have tried 3 other brands of flea and tick control for our hound mix. We recently moved from the city to the USA countryside and he got fleas 3 times since moving here. Obviously in the city Berlin, Germany We never had any issues. We finally decided to try K9 Advantix II and all the fleas died. Immediately. It is really the only one that does what it is supposed to do. Would definitely recommend to anyone. Our dog weighs 58 pounds so I was nervous putting this on him as it is for dogs 55 pounds and over so that is very much poisonous material to put in an animal. It doesn't bother him and we have no flea issues. Five stars.
Date published: 2016-08-20
Rated 4 out of 5 by from It makes my dog act strange It has been working pretty good against fleas and ticks, but every time I apply it on my 2 year old German Shepherd Husky Mix he starts acting weird. He is normally an overly affectionate dog to the point where it's annoying. He'll always sleep in your bed and he'll always wanna lay right next to you, but after each dose we've applied on him he becomes distant for a few days and prefers to sleep on the floor. After each dose is applied he does this for a few days and then one day he's back to normal. Granted this isn't an adverse reaction, but it's just really noticiable to us because he isn't acting like himself.
Date published: 2016-08-20
Rated 5 out of 5 by from Excellent Product I have been buying this Flea,Tick and mesquito product since it first came out. I have never had one bad issue with it what so ever and will continue to use this for as long as I own dogs.
Date published: 2016-08-09
Rated 4 out of 5 by from Shepherd puppy medication and price are great,but my puppy is growing so fast that only one out the 4 pack is will get used
Date published: 2016-08-05
Rated 5 out of 5 by from Works perfectly for our dog We've used this product since we got our dog, about 3 years. Our dog (70 pounds) has never had adverse reactions, even with her sensitive skin. We have ticks and mosquitoes in the area, but have only ever seen 1 tick on her and no mosquito bites. The tick we found we removed the shortly after it embedded, but it was dead (like the product advertises). It does not seem to work on flies, just for extra information. I would not consider switching flea/tick/mosquito products unless medically necessary.
Date published: 2016-08-02
  • 2016-08-24T06:05CST
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Q&A

Do you require a prescription for this item?

Asked by: Connie
No you do not need a prescription for Advantix II.
Answered by: paulpharmacistintern
Date published: 2016-08-18

hi I just bought k9 advantix ii I was wonder if I have to shower my dog before applying it 

Asked by: Rose
It's not necessary, but might make administering easier with a clean coat.
Answered by: paulpharmacistintern
Date published: 2016-08-17

I have been told it was not safe to use K9 Advantix II along with Heartguard...Is that true?

Asked by: Jmiller2010
These medications can be used together normally. Contact your veterinarian about concerns for your specific pet.
Answered by: paulpharmacistintern
Date published: 2016-08-11

My puppy is only 6 months. Is he too young, for this?

Asked by: henry
It can be used on your puppy. It can be started on dogs 7 weeks of age or older
Answered by: paulpharmacistintern
Date published: 2016-08-11

How long does the first application last

Asked by: Roland 58
Each application provides one month of protection against ticks, fleas, mosquitoes, biting flies.
Answered by: paulpharmacistintern
Date published: 2016-08-10

What can happen if dogs are double dosed with flea meds

Asked by: Susan
In the event of overdose: Contact your veterinarian or veterinary emergency room.
Answered by: Cherley Petmeds Pro
Date published: 2016-08-03

Can this be used with sentinel spectrum or nexguard?

Asked by: Brittany
Yes it can be used with either medication.
Answered by: paulpharmacistintern
Date published: 2016-08-03

How long after applying medication can I give my dog a bath?

Asked by: Crystal
Give it a good 24 hours before bathing your dog preferably with just soap and water.
Answered by: paulpharmacistintern
Date published: 2016-08-03
  • 2016-08-24T06:24CST
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