Treatment of Fibrosarcoma in Dogs and Cats
The treatment of choice for most fibrosarcomas is attempting to surgically remove the mass; however, because of occasional incomplete removal, up to two-thirds of cases may recur. With vaccine-associated fibosarcomas, rates of recurrence may be over 90%. Therefore, it is recommended that initial wide surgical removal of vaccine-associated sarcoma be done by a surgical specialist who can remove as much surrounding tissue as possible. Given the large size and/or infiltration into surrounding tissue, a cure is much less likely in pets with oral fibrosarcomas and vaccine-associated sarcomas with surgery alone. In these cases, adjunctive radiation therapy is often utilized to enhance efficacy of treatment. Radiation therapy may even be used as primary therapy in pets with oral fibrosarcoma, where surgery is not possible. With vaccine-associated disease, radiation therapy should be scheduled within 10-14 days of surgery for maximal benefit and clinical results. Chemotherapy may be helpful in certain forms of skin fibrosarcoma in dogs with drugs such as Dacarbazine, Doxorubricin, Cyclophosphamide, and Carboplatin. For cats with vaccine-associated disease, however, chemotherapy has been much less helpful.
Prognosis of Fibrosarcoma in Dogs and Cats
The prognosis for fibrosarcoma treatment will depend on the location, size, grade, and if vaccinations are involved as causative agents. No matter where the location, without wide surgical resection, fibrosarcomas do have a high likelihood of recurrence. In cases not amenable to complete surgical removal, and in cases that have recurred, prognosis will depend on response to radiation therapy. Oral and vaccine-associated sarcomas tend not to spread to distant areas; however both are very aggressive with local invasion. Combination surgery and radiation therapy offer the best options in these cases.