Know the Side Effects of Diuretics
Diuretics are generally safe, when used as directed. However, they do have some side effects. Side effects or signs of toxicity or overdose may include dehydration accompanied by excess thirst and decreased urination, or electrolyte imbalance accompanied by weakness, drowsiness, restlessness, dizziness, stumbling, and muscle pain or cramping. If any of these side effects occur, contact your veterinarian right away.
HCTZ and Furosemide should not be given to animals allergic to sulfa drugs such as SMZ/TMP, Albon, or Primor. Spironolactone should not be given to animals with Cushing's disease treated with mitotane (Lysodren), or animals that are being treated for Addison's disease.
Your pet needs to eat and drink well to reduce the risk of side effects. Furosemide should not be used in animals that don't produce urine, have progressive kidney disease, electrolyte imbalances, liver disease, diabetes mellitus, vomiting, or diarrhea. Diuretics should not be used in pregnant animals, or nursing animals. Your veterinarian should be consulted before giving your pet any other medications, including vitamins and supplements, since interactions may occur.