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Trifexis 388 392
Cocerned of the side effects The side effects of vomiting, excessive itching, licking and hyperactivity, immediately showed up in my Doberman. We only had her on it for 4 months then took her off. 06/01/2014
Dont waste your money! I was talked into trying this product by our ex-vet, who claimed it was the best product since the chew toy. We spent almost $500 on 6 month supply for our 4 dogs. We have never been so disappointed in a flea product. Fleas would be kinda controlled for a week or so after taking the pill, then they would continue as if nothing had happened. A waste of time and money. 05/31/2014
It Works! Great product but after my dog had some complications with abdominal issues, vomiting, diarrhea and gas pains, the Vet recommended we cut the pill in 1/2 and administer is w few days apart. This really helped. My dog is 16lbs. Half your pills everyone!! 05/29/2014
Nothing is working We had a flea infestation and the worst part is none of my pets are "outdoor" pets!! We have a screen enclosed pool/patio that is huge. Our Shi Tsu was on Sentinel and I was told this protected her against fleas, too. WRONG. Not from ADULT fleas anyway so we took her to the vet and they put her on Comfortis + Sentinel we bathed everybody (fun with the cats), bombed, powdered the rugs that couldn't be washed, sprayed and laundered everything, put Advantage II every week on the kitties and every two weeks for our Shi Tsu. She STILL got fleas again! Back to the vet this time Trifexis + Sentinel (you have to protect them from heart worm for 3 months until that action of Trifexis is adequate) then another flea shampoo and sprayed her down every time she stepped paw out of the house. The other day she was scratching her ear and sure enough there was a flea!! She is constantly scratching, chewing, biting, licking herself (probably flea dermatitis at this point). We cut back to bathing her to once a week so we don't wash the Advantage II off and have dosed the cats again but this time with the large volume. We have one spot on the pool deck that used to have Bromiliads growing but we dug that up last year and put rock. Now I am thinking we are going to have to cement that in too. I am wondering if she may weigh 10.1 lbs. now and may need the higher dose because NOTHING is working against these Florida fleas!! 05/14/2014
Happy but with a question We started on Trifexis yesterday - both of my dogs took it well, and had no vomiting or other problems. My question is about the warning to not use on breeding dogs. We have plans to breed our Whippet in a year or two. How early do we need to stop giving her Trifexis before we plan to breed? Is 1-3 months enough, or should we take her off the medicine before that? What are the problems found when used in breeding females? Something wrong with the puppies, or what? 04/23/2014
Great product I have been giving my American Bulldog Trifexis for a year and a half and am glad my vet recommended it. We had been using another heartworm med that required the use of topical flea and tick protection so the all in one aspect is great. My dog refused to eat the tablets even though I told him they had a nice beefy flavor. Smothering the tablet in peanut butter worked a few times, but he started licking it clean and spitting it out. I checked with the vet who told me that swallowing it whole would be okay, so now I give it like a pill, with no ill effects. 04/21/2014
Love It Love this product because Jojo has very sensitive skin. Uses to use the topical product each month and it would drive him crazy scratching and scratching. It drove me crazy watching him suffer itching and itching. With Trifexis, he ate the tablet with no problems and he did not have a bad reaction and no flees. 04/19/2014
feed before you give. thank goodness a product that prevents fleas and heartworms. i put a pill under some food, soft in a bowl and dog eats food and apparently loves pill. seems to like crunching it on back teeth. good stuff. 04/18/2014
Great Product Moved to LA about a year ago from Vegas. Vegas was too hot for fleas and mosquitoes. I didn't even think about it when I moved here. So first couple weeks after we arrive, fleas are everywhere!!! Tried everything topical and they just weren't working. Even cleaned my house every day, washed everything, couldn't keep the dang things out. The vet recommended Trifexis & BAM immediately they stopped scratching & the fleas stopped feeding off me too. (the dogs sleep in the bed). We haven't had any problems with side effects. I was worried since my girl dog has a really sensitive stomach. I give them the pill after dinner, which I include a little bit of wet food. They take it with no problem, they think it's a treat. Been using it for almost a year and neither dog has shown any side effects. Maybe just extra thirsty and extra trips outside, but that's normal. 04/14/2014
Trifexis works better than any other! I have a 3 year old pit bull and he has very sensitive skin. Mosquitos and fleas would make him break out all over before he started taking Trifexis. Since he's been using Trifexis (about 2 years), bugs stay away from him. Only downside is that I have to cut up the pill into 1/4 and give it to him in lots of peanut butter or he won't eat it. He does not have any side effects after he takes this pill. 03/31/2014
Seems to cause trouble for some I switched from Sentinel to Trifexis because we got it free from a relative who worked at a vet. We gave it to our dog (6-yr old lab mix) at the beginning of the month. Three weeks later, our dog got diarrhea and a couple days after that vomited while at home. After taking him to the vet, bloodwork came back for him being positive for roundworm. I can't say for a fact that Trifexis was the cause of all that, but after seeing some reviews on Trifexis (including here on 1800petmeds) about nausea, vomiting and diarrhea for some dogs (although nothing about roundworm), I've quickly decided to go back to Sentinel for treatments. If you do choose Trifexis, just monitor your dog and know ahead of time the possible side effects. 03/30/2014
It WORKS! I've been through it with him. Fleas, the scratching, the gnawing, persistent flea dirt , I finally cornered the vet, FIND SOMETHING THAT WILL WORK! Trifexis has done it. I cant say it's inexpensive, he's a big boy it takes double for him. But he is protected. No more fleas, scratching, gnawing, chasing his tail to get to them. This Mama is happy- 03/14/2014
great results I have used Trifexus for over a year now for my Malamute 96 lbs and my male German Shepard 1 1/2 years old have hav e had no problems with fleas or anything else and they get a HEALTHY report from the Vet on their annual visits. I strongly recommend it. 03/12/2014
Works great but horrible smell! We have two lab/shepherd mix, that are our children. Our Vet discontinued offering Sentinel and now only offers Trifexis. The pills smell horrible!! Our dogs refuse to take them, we've tried peanut butter, beef and chicken, but they can smell the chemicals in the pills, if we can smell it surely THEY can. We have to split the pills in half and shove them down their throats, not a very pleasant experience for our 15-year old. Going to see if our Vet will give us a prescription for Sentinel. 03/11/2014
I noticed my dog would just lay around for 2 days after her med. (trifexis). Seemed like she was not feeling good at all. One day I had the news on tv and the were discussing the side affects of trifexis. The report was some dogs had died due to the meds. So anyway I took my dog off it. Now I am so confused as what to do. I have read good reviews but also bads ones. 03/09/2014
My dog hates this I have tried month after month to give this to my mini poodle. I can't hide it in anything: cheese, peanut butter, steak, nothing. This stuff smells horrible and the pill is so large. I am telling my vet I refuse to keep shoving this down my dog's throat. I'll find something else or find another vet. 02/24/2014
Side effects Be very watchful of dog when first starting and each month after you give. I have two dogs both same age and one dog suffered seizure. When taking walk he just stopped walking and fell over. Quite frightening as I had to carry him home and in about 1/2 hour he was fine. Did not think it was Trifexis. Then the next month again it happened. so please be aware as the side effects can happen. Other dog is fine and product works so owners just need to be watchful 02/23/2014
Not so good Going back to Heartguard. 02/16/2014
Horrible Taste I have been using Trifexis for years but every month it is a terrible battle to try and get her to take the tablet. I don't blame her either. The tablet smells terrible!! It's supposed to be chewable but my dog runs from it. She won't take it. I've tried mixing it with peanut butter, cheese, her favorite food, etc. I've tried breaking it down into a powder and mixing it so she can't see it. But she still smells it!! She absolutely hates this pill. Why anyone would invent a necessary product that does not both smell and taste delicious to a dog is beyond me. That should be the #1 test that it has to pass in the Quality Assurance cycle. Well, maybe #2 if effectiveness is #1. Anyway, she hates this pill. I have tried everything. I don't blame her because to be honest it smells terrible even to me. I get it on my fingers and it's disgusting. So now both my dog and I both dread Trifexis day. So I'm looking around at other options now. Has to be something as effective but better tasting. 02/13/2014
I was using topical for fleas and ticks and no matter which one I used the fleas seemed to be immune to all of the topicals. After switching to Trifexis after the second dose I have not had any fleas on my dog or in the house. I will use Trifexis. Had no problems with vomiting usually give with a piece of cheese. 02/12/2014
Stop the vomitt Trifexis is a great product. I wanted to try again. It was suggested to me that I give a small can of wet dog food with the Trifexis. It worked like a charm. I am lucky to have a vet assistant (actually 2 of them) as very close friends. They sure gave me great advice. Glad I actually listened for once. (LOL) 02/02/2014
Fantastic Product I have a 92 lb Boxer. I made sure I fed her first then I broke the tablet in half and smothered it in peanut butter. She ate the whole thing. Within the hour she stopped scratching and hasn't scratched since. It has been 3 weeks so far. Only thing, she did vomit once within a 24 hour period but has been fine since. I highly recommend this product. Some people complain the pill is too big, but I've given my dog biscuits bigger than this tablet. As I said, I broke it in half and put peanut butter on it. She loved it. And, no more fleas!!!!! 01/22/2014
It works great, but... I have not encountered a single problem with this product and I have been using it on all three of my dogs for the past six months... Except my dogs HATE the taste. I have to shove it down their throats. Other than that, it's a great all-in-one product and I will continue to use it as well as recommend it to all my fellow pet lovers! 01/10/2014
Works but allergic reaction I tried this because my mother-in-law was referred from her vet to give it to her dog and she told me to get it for my dog also. Yes, it does work great at killing and keeping away the fleas. BUT... both of are dogs had allergic reactions to the medicine. Hers more so than mine. My little one is broke out all over now from a allergic reaction to her skin from it. I know it is from the medicine and not fleas because we haven't had them since September. It did not start until I gave her the pill about a week or so ago. Now have to go to the vet to get her a shot to keep the itching and swelling down. If you are considering this for your dog, please please please go over it very well with your veterinarian to make sure this is the right medicine for him or her. 01/02/2014
sticktight fleas I bought this product from my vet as I liked the idea of all in one. However a couple of weeks after taking the first dose our golden mix started chewing and licking her tummy and the inside of her leg. She had little red spots on her which became inflamed due to her constant chewing. I took her in to see the vet and told him that the only change was to the trifexis. He treated her and the next month it returned again. Another vet noticed a sticktight flea in the inflamed area. Not sure where she picked up this flea (bird/chicken flea,) but they burry in the skin like a tick. Called the trifexis company and they do not cover that type of flea. I will now have to go back to the topical and heartworm separately to make sure our dogs do not get this nasty sticktight flea. 12/26/2013
urination? I have 3 frenchies and this product is awesome. However, my female urinated in her sleep for a few nights after giving it to her. She did it 3 out of the 4 months given to her. Anyone else have this issue? I don't know if its related but wanted to ask. She has never done that before and it happened about 3 nights after being given (for each night). Maybe just a coincidence? I thought she slept extra heavy ? 12/21/2013
Love its 2 pills in one We had been using different products for fleas and heartworm. The pill is large and we break it up and serve it with some peanut butter. 12/07/2013
works great My Welsh Corgi will NOT eat this pill! I have mixed it with everything: beef, chicken, lunchmeat, but every time he would separate the pill and spit it out. I bought a mortar and pestle to crush the pill and then soak it up with lunch meat and he readily gobbles it down. 12/01/2013
Great product My dog is extremely allergic to flea bites. The popular topical products work by killing the fleas AFTER they bite, this caused major problems for my Irish Setter. This product gets rid of the fleas without the biting and the results are immediate. Give with food as directed and see the results within 30 minutes. Pretty amazing and worth the additional cost. Finally some relief for our fury family member. 11/26/2013
Give Trifexis on a FULL stomach We gave our Shih-Tzu Trifexis and she threw up all over the place. We took her to the Vet and it was stressed to us to not give her the pill on an empty stomach. A lot like human pills, many of them you shouldn't take on an empty stomach. So, please always give your dog Trifexis on a full stomach. 11/10/2013
227 Questions · 348 Answers
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Talk to other pet lovers about this product.
My dog is 59.8lb, and will probably get bigger because he's 7 months old. Can I just purchase the 60.1-120lb range pack without it harming him?
will it still be effective if my pup vomits or gets diareha? or does it leave her system?
Answer:As long as your puppy does not vomit until 1-2 hours after giving the Trifexis, the medication is already in your puppy's system. However, if your puppy vomits under an hour after giving the Trifexis, you need to redose. Having diarrhea will have no affect on the effectiveness of the Trifexis.
The Trifexis box was on top of my toaster oven when my friend came over and heated a bagel. The encased pills inside were heated for about 15 minutes on top of the metal surface. Will this render them ineffective, or harmful to use?
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