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Proin

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Starts $24.99 $17.99 
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25 mg Chewable 60 ct
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50 mg Chewable 180 ct
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50 mg Chewable 60 ct
$31.24
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75 mg Chewable 60 ct
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Proin?

Proin is an aid in the management of urinary incontinence in dogs. Proin requires a prescription from your veterinarian, and is considered a controlled substance in Arkansas, Iowa, Louisiana and Oregon.

Proin is unavailable to be shipped to Arkansas, Iowa, Louisiana, Oregon or Internationally.

For:

Dogs

Benefits:
  • Is a supplement for urinary incontinence in dogs
  • Ensures sustained phenylpropanolamine levels in the blood stream and may help reduce the conditions often associated with high levels of phenylpropanolamine such as: decreased appetite, changes in heart rate, increased blood pressure, hyperexcitability
How it Works:

Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage.

Cautions:

Don't give Proin with ephedrine or epinephrine, and don't give it within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar. Possible side effects can occur, including restlessness, or loss of appetite, difficulty breathing, hives, and swelling of the lips, tongue, or face. If these or any other side effects occur, contact your veterinarian immediately. Proin is unavailable to be shipped to Arkansas, Iowa, Louisiana, Oregon or Internationally.

Brand Name:

Proin (PRN Pharmacal)

Generic Name:

Phenylpropanolamine

What is the most important information I should know about Proin:

Proin is a prescription medication for veterinary use in dogs. Proin is available as 25mg, 50mg and 75mg chewable, liver flavor tablets. Proin may cause restlessness, irritability, or loss of appetite.

What is Proin:

Proin is an adrenergic agent used as a supplemental product for urinary incontinence in dogs. Proin may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving Proin to my pet:

Tell your veterinarian if your pet has ever had an allergic reaction to this medication. Tell your veterinarian if your pet has glaucoma, hyperthyroid disease, diabetes, heart problems or high blood pressure. Tell your veterinarian if your pet is pregnant or lactating.

How should this medication be given:

The usual dose for dogs is 0.4-0.8mg/pound every 12 hours. Give Proin exactly as directed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Proin at room temperature away from moisture and heat. Keep this medication away from children and pets. 

What happens if I miss giving a dose:

Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose the pet:

Seek emergency veterinary medical treatment. Symptoms of overdose may include increased blood pressure, increased heart rate, seizures or coma.

What should I avoid while giving Proin to my pet:

Do not give Proin with ephedrine or epinephrine and do not give within 2 weeks of using an MAOi such as selegiline or Preventic Collar.

What are the possible side effects of Proin:

Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.

What other drugs will affect Proin:

Before giving Proin, tell your veterinarian if your pet is being given digoxin, NSAIDs such as aspirin or Rimadyl, tricyclic antidepressants such as clomipramine, and beta blockers such as atenolol, or any other prescription or over the counter medications. 

Where can I get more information:

Your pharmacist has additional information about Proin written for health professionals that you may read.

How to Use
Directions:
  • Proin liver flavored chewable tablets are available by prescription for use in dogs to treat urinary incontinence.
  • Proin may cause restlessness, irritability, or loss of appetite.
  • Tell your veterinarian about any other medication you may be giving your pet.
Tip:

Give this medication exactly as directed by your veterinarian. Do not exceed 1.8mg/lb per day. The medication may be given with food.

Dosage:
Dogs:
Weight
Dosage
All weights
The usual dose for dogs is 0.4-0.8mg/pound every 12 hours.
Cats:
Do not use!
Horses:
Do not use!
Storage:

Should be stored at room temperature away from moisture and heat. Keep this medication away from children and pets.

Ingredients
Proin Chewable Flavor Tabs 25 mg:
Active Ingredients
Strength
Phenylpropanolamine
25 mg
Proin Chewable Flavor Tabs 50 mg:
Active Ingredients
Strength
Phenylpropanolamine
50 mg
Proin Chewable Flavor Tabs 75 mg:
Active Ingredients
Strength
Phenylpropanolamine
75 mg
Customer Reviews
Proin is rated 4.7 out of 5 by 623.
Rated 5 out of 5 by from It's inexpensive and works great! My german shepherd needs this med and it was quite expensive buying it from our vet. Buying it through this site cuts our monthly cost in half!
Date published: 2017-02-24
Rated 5 out of 5 by from Great Product! 2 of my females take Proin and it works!!! My Pit mix has been taking it for over 4 years and my bully mix just recently started taking it. Proin is a life saver for us all--LOVE the product and highly recommend it!!
Date published: 2017-02-24
Rated 5 out of 5 by from Proin is,a life saver My Dog not only loves the taste, Proin has made my life and hers much more comfortable. She never had accidents even as a puppy until recently. She's 12 yrs old & jus started having incontinence problems. In the early mornings, I was surprised to find her bed wet & she was too. I was washing her bedding everyday for a week until my Vet prescribed & gave me Proin that I started 2 pills in the morning & 2 at night. Honestly, these chewable meds are a miracle because by the 3rd morning, there was no wet bed and has not been since. The price of PetMeds was a plus and definitely lower than my vets with double the amount. I've told many people about how great this medication is. Thank you PetMeds for your fair pricing & discounts as well:))
Date published: 2017-02-11
Rated 5 out of 5 by from Resolved issues and dog doesn't mind flavor This was prescribed for my elderly old lady, it started working within a few days. She can "hold it" for 8 hours now if she needs to and she happily eats it, no issues with her spitting it out. I just drop half a tab in with her kibbles and she snarfs it right down. Quite happy with this medication.
Date published: 2017-02-10
Rated 5 out of 5 by from Finally! Proin at a 25mg dose 2xs a day effectively halted my puppy's incontinence, almost immediately. She had 2 hernias as a puppy that were repaired during her spay operation at 4 months old. We hoped the surgery would fix her incontinence but it didn't. She continued to have up to 4-5 accidents a day. Proin was prescribed by our vet and it's been a life saver. She is more confident and we are both relieved!
Date published: 2017-02-08
Rated 5 out of 5 by from No more leaking Our spayed westie developed sleep incontinence at age 6 and Proin took care of it. Our vet said it would have an immediate effect (within a couple of hours) and that was the case with us. Dosage is based on weight. I wonder if some of the reviewers who indicate it took a while to "work" were initially giving a high enough dose, but it is also a good idea to start low and increase the dose to what works and no more. I would also recommend asking your vet to check your dog's blood pressure before beginning Proin if there is any chance your dog could be hypertensive. It is also very palatable to dogs so make sure to keep the bottle out of their reach so they don't overdose.
Date published: 2017-02-03
Rated 5 out of 5 by from Works great My dog has been taking Proin for a while now and we could'nt be more pleased with the results.
Date published: 2017-02-03
Rated 5 out of 5 by from Really works! Took a little bit to fully kick in, but has made a significant difference in my basenji's incontinence problem!
Date published: 2017-02-02
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Q&A

Do I need a vet prescription to buy meds?

Asked by: Jorge
Yes, Proin requires a veterinarian's prescription.
Answered by: SuzyCVT
Date published: 2017-01-19

Can proin tablet be swallowed even if it's chewable

Asked by: diane
Yes, it will still be effective even if swallowed whole.
Answered by: SuzyCVT
Date published: 2017-01-12

I have a 4 month old Doberman who pees on couch, stairs, while she is just walking awAy. But she can hold it thru the night from 11pm-7am and when she is crated nothing! She was on antibiotics twice. No UTI is she old enough to try Proin???

Asked by: Tray
Proin may not be the solution you need as your dog does not seem to have urinary incontinence. Give her more time to grow up and to become fully housebroken. The urination may be a submissive behavior which she will hopefully outgrow.
Answered by: SuzyCVT
Date published: 2017-01-12

Does proin cause sleeplessness or change in behavior?

Asked by: Ellie may
Side effects of Proin include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite.
Answered by: Christine
Date published: 2017-02-24

Can I cut the chewable tablets? I currently have a prescription from the vet but they are 50 mg pills that I break in half. It's much cheaper to order here but I'm worried the chewable may he different than what I currently have.

Asked by: Britney
Yes, the chewable tablets are scored and can be easily cut in half.
Answered by: Christine
Date published: 2016-10-31

What are side effects of this medication

Asked by: Donna
Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.
Answered by: Christine
Date published: 2016-10-31

How much is the large size of Proin 50?

Asked by: Annie
Pricing depends on both the size and the strength of medication. 60-count of the 25 mg pills cost $17.99 with our "TOPTEN" coupon. Our 50 mg chewable tablets are available in 180-count and 60-count. The 180-count costs $53.99 with our "TOPTEN" coupon. 60-count of the 75 mg chewable tablets costs $26.99 with our "TOPTEN" coupon.
Answered by: Christine
Date published: 2016-10-12

Can nexgard be taken with proin 

Asked by: Jr1289
Yes, NexGard can be taken with Proin.
Answered by: Christine
Date published: 2016-10-10
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