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Monthly heartworm prevention in a chewable tablet.
  • Prevents heartworm disease
  • Prevents development of adult stage heartworms
  • Treats and controls roundworms
  • Treats and controls hookworms
  • Beef flavor chewable
  • For dogs only

    Heartgard Plus Chewables

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      Product Info   How to use   Ingredients   Customer Reviews   Q & A  

    What is Heartgard Plus?

    Heartgard Plus is a real-beef chewable tablet for dogs that provides protection against heartworms, and treats and controls roundworms and hookworms. Heartgard Plus is given monthly and requires a prescription from your veterinarian.
    For: Dogs (6 weeks of age or older and no weight requirement)
    Considered the most tasty heartworm chewable tablet (beef flavor)
    Effectively controls heartworms, roundworms & hookworms
    Only given once a month

    How it works:
    Heartgard Plus contains ivermectin, a broad-spectrum antiparasitic medication used to prevent heartworms. Heartgard Plus also contains Pyrantel Pamoate, an anthelminthic, used to prevent roundworms and hookworms.

    Studies have indicated that certain dogs of the herding breeds are more sensitive to the effects of ivermectin administered at elevated dose levels due to the MDR1 gene. For a full list of dog breeds that may be affected, click here.

    Can cause sensitivities in herding dog breeds. Heartgard Plus chewable tablets should be chewed, not swallowed whole. The tablets may be broken into pieces and fed to dogs that normally swallow treats whole. Make sure that your dog eats the entire dose. It is important to give your dog Heartgard Plus every month year-round. Do not skip winter months as your dog may become infected. If you miss more than two months of dosage, please consult with your veterinarian as to whether to continue medication.

    More Information:
    Brand Name
    Heartgard Plus (Merial), Iverhart Plus (Virbac), Tri-Heart Plus (Intervet)
    Generic Name
    Ivermectin, Pyrantel pamoate

    What is the most important information I should know about Heartgard Plus: Heartgard Plus is a prescription medication available as beef flavored chewable tablets. The usual dose of Heartgard Plus in dogs up to 25 pounds is 68mcg/57mg (Blue box), for dogs 26-50 pounds is 136mcg/114mg (Green box), and for dogs 51-100 lbs 272mcg/227mg (Brown box). Dogs over 100 lbs are given a combination of tablets. The chewable tablets must be chewed and should not be swallowed whole. For dogs that normally swallow whole, the chewable tablets can be broken into pieces.

    What is Heartgard Plus: Heartgard Plus is given to dogs once a month for the prevention of heartworm disease. Heartgard Plus also protects against hookworms and roundworms in dogs. It is recommended by the American Heartworm Society that heartworm prevention be used year round. Heartgard Plus may also be used for purposes other than those listed in this guide.

    What should I discuss with my veterinarian before giving Heartgard to my pet: Tell your veterinarian if your pet has ever had an allergic reaction to the medication, any of its individual ingredients, or to beef.

    How should this medication be given: Give Heartgard Plus exactly as directed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Heartgard Plus chewable tablets must be chewed. They should not be swallowed whole. Use with caution, Collies and other herding dog breeds have been known to have adverse reactions to invermectin administered at elevated dose levels. Heartworm testing should be performed prior to the start of prevention therapy. If the animal is off Heartgard Plus for 6 months or less, start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Heartgard Plus at room temperature. Do not remove the tablet from its wrapper until ready to give the medicine. Keep this medication away from children and pets. In addition, Heartgard Plus has shown a wide margin of safety at the recommended dose level in dogs including pregnant or breeding bitches, stud dogs and puppies aged 6 or more weeks.

    What happens if I miss giving a dose: Give the missed dose as soon as you remember. Do not give a double dose of the medication.

    What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include vomiting, diarrhea and incoordination in dogs.

    What should I avoid while giving Heartgard Plus to my pet: Because humans can contract hookworm from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on the pet and in the household and to not feed the pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.

    What are the possible side effects of Heartgard Plus: Side effects of Heartgard Plus are rare at the recommended heartworm prevention dose. Higher doses in dogs may cause tremors, dilated pupils, and loss of body weight and death.

    What other drugs will affect Heartgard Plus: Do not give Heartgard Plus to your pet if already taking another heartworm medication.

    Where can I get more information: Your pharmacist has additional information about Heartgard written for health professionals that you may read.

    Give Heartgard Plus Chewables once a month on the same day of each month year round.
    Heartgard Plus Chewables are for dogs only. Do not give to cats.
    Heartgard Plus Chewables should not be swallowed whole.
    Chewables may be broken and fed to dogs as pieces, or crumbled and mixed with food.
    Watch dog closely following dosing to be sure the entire dose has been swallowed. If it is not completely swallowed, give one more full recommended dose as soon as possible.
    Tip: Do not remove chewable from its wrapper until ready to give to pet.
    Pet Weight Dosage
    Dogs/Puppies: (6 weeks of age and older) Up to 25 lbs Give 1 chewable every month (Blue Box)
      26-50 lbs Give 1 chewable every month (Green Box)
      51-100 lbs Give 1 chewable every month (Brown Box)
      Over 100 lbs Give combination of chewables based on weight
    Storage: Store this product at room temperature. Keep out of reach of children.
    Heartgard Blue Chewables (for Dogs 1-25 lbs):
    Active Ingredient Amount
    Ivermectin 68 mcg
    Pyrantel 57 mg

    Heartgard Green Chewables (for Dogs 26-50 lbs):
    Active Ingredient Amount
    Ivermectin 136 mcg
    Pyrantel 114 mg

    Heartgard Brown Chewables (for Dogs 51-100 lbs):
    Active Ingredient Amount
    Ivermectin 272 mcg
    Pyrantel 227 mg

    Heartgard Plus Chewables 4.8 5 882 891
    Dogs think it is a treat! We have been using Heartgard going back to when it was in pill form only and this chewable makes it easier on you and your pet. We have been using it ever since it came out on the market and it is highly effective, living in the south where mosquitos exist year round our dogs also receive it every month, Making certain that they got this medication is vital, with the chewable you watch them joyfully ingest it as they think it is a treat. In pill form, with con artists you are not certain whether they actually swallowed it or not. The additional "Plus" of protection against Ascaris and Hookwook infestations touched home when our new puppy, who had been given injections of Heartworm preventative medication only received his first dose of Heartgard Plus. He had been having loose stools and gas. The very next morning when I took him outside to the bathroom and he had his first morning bowel movement I saw the cause of his loose stools and gas: Round worms (Ascaris). Well, they certainly did not like the Heargard Plus either! I did take him to our Vet and we followed up with some meds just to be certain we rid him of all of the life stages of the worms. As a Med tech for 30 years, I know my intestinal parasites. 1-800-PetMeds and especially Peter, were eixtremely helpful in expediting this medication delvery for me. I will continue to do business with 1-800-PetMeds because of Peter's professionalism, service and effeciency. Thank you. 05/13/2011
    100% satified Am a for ever petmeds customer.heart guard and advantage 2 really good for my lab BUDDY. Great customer service thank you 04/12/2011
    Heartgard is a great product. 11/19/2014
    Customer Service comes through! My original order of Heartgard was held up in a post office somewhere for a long time. The company replaced it without question or charge. When the original package showed up,after the replacement order arrived, the box was completely crushed and the medicine had been exposed to air for some amount of time. Thanks for the great service 10/31/2014
    Easy Fought w/trying to give other brand, had to literally jam down throat, hated doing that so thought I'd give this a try. Couldn't loose because of money back guarantee, unlike at Vet's office. No problem, he thought it was a treat! Yea. 10/27/2014
    2 3 4 5 ... 31 Next
    658 Questions · 958 Answers

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    0 answers

    Heartguard Plus

    I have 4 dogs, 3 who are in the same weight class(51-100lbs) and one weighs 25 lbs. I can only purchase a 3 month supply for each of the 4 dogs. I have RX from vet. what's the best way to purchase?
    1 week, 3 days ago
    Answer this question
    1 answer

    Heartgard Plus

    Cam I give this to my nursing mother dog ?
    2 weeks, 4 days ago
    Answer this question


    yes, it has proven to be safe when used in pregnant and nursing dogs
    2 weeks, 1 day ago
    Linda M 1800petmeds pharmacist
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    3 weeks, 4 days ago
    Answer this question


    Thank you for your question. No, this should not be split in half. The entire dosage needs to be given to your dog to ensure proper coverage.
    3 weeks, 3 days ago
    Maureen PetMeds Pro
    Pompano Beach, FL
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    1 answer


    I have a script for 6 month of heartgard and one refill. Can i just order the 12 month package?
    1 month, 1 week ago
    Answer this question


    Thank you for your question. Yes, you are able to do so.
    1 month ago
    Maureen PetMeds Pro
    Pompano Beach, FL
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    2 3 4 5 ... 23 Next
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    This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
    Note: Any trademarks are the property of their respective companies.
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