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Compare Frontline Plus to Frontline Tritak
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Frontline Plus
Frontline Plus
Starts $52.74 $37.97
Frontline Tritak
Frontline Tritak
Starts $66.24 $47.69
Kills Fleas
Repels Fleas
Kills Flea eggs and Larvae
Kills Ticks
Repels Ticks
Kills and/or Repels Mosquitoes *
Prevents Heartworm
Other Parasites Information Eliminates infestations with chewing lice, aids in the control of sarcoptic mange infestation
(shampooing once a week can reduce effectiveness)
Safe for pregnant or nursing Pets Consult your veterinarian.
How long does it take to work Kills Fleas within 12 hours and Ticks within 48 hours Frontline Tritak will quickly and easily get rid of any existing fleas and ticks on your pet . Starts killing ticks in as little as 1 hour
Taste Applied to Skin Applied to Skin
Active Ingredient(s) Fipronil/(S)-Methoprene Dogs: Fipronil (9.8%), Cyphenothrin (5.2%), (S)-Methoprene (8.8%) Cats: For Cats: Fipronil (9.8%), Etofenprox (15.0%), (S) Methoprene (11.8%)
Rx Prescription Required(Details)
Dosage Monthly Monthly
Video coming soon
Video coming soon
Veterinarian Review
(Michael Dym, VMD)
I find that the effective combination of an ingredient like fipronil, along with the insect growth regulator methoprene, provides the best spectrum of activity and protection against all stages of the flea life cycle from egg through larval stage on to adult. Because of these two main ingredients and their method of action, I find that clients don't have to treat the environment as much. I find that this product tends to be safer in smaller breed animals when compared to its competition. I find its tick efficacy quite good. The fact that it is waterproof also allows clients, whose pets swim frequently, to confidently use this product during the swimming months. I also find that this product works the longest for fleas, while some of the competitive products have to be reapplied before the end of the month. The lack of label efficacy against mosquitoes and flies, as well as the fact that this product does not repel fleas or ticks are the two main disadvantages. As with any insecticidal products, I find that every pet is an individual, in terms of which of the products works best on them. When I am dealing with more of a flea issue in a patient, this is the product I will likely reach for first. From one of the most reliable drug companies Merial, makers of Frontline Plus, is Tritak, which was introduced a few years ago, and offers a three prong protection against multiple parasites, including fleas, ticks, chewing lice and mites. This is probably one of the most rapidly effective topical products available, often beginning to kill fleas within 5 minutes of application. The extra insect growth regulator ingredient methoprene allows this product to also kill flea eggs and larvae as well. I have seen excellent results with this product for at least 30 days when it is applied as directed, although I usually recommend that clients not bathe their dogs 2 days before or for 2 days after application. I have seen occasional contact allergic reactions at the application site, consisting of a mild hair loss and/or dermatitis. The rare sensitive pet also may experience digestive upset as well. In my few years of using this product, I have seen only one animal to develop a neurological reaction after application. However the safety record of this product is overall excellent. Because it is so safe and effective in the vast majority of pets it is used, I give this product an overall rating of a 4, with an ease of application of a 4 as well.

*Claim approved by the US Environmental Protection Agency; not by California E.P.A.

Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors.

The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.

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