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Dorzolamide HCL Ophthalmic Solution

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Dorzolamide HCl?

Dorzolamide HCl is indicated for use in the treatment of glaucoma (increased ocular pressure). Elevated intraocular pressure is a major risk factor in the development of optic nerve damage and glaucomatous visual field loss. Dorzolamide HCl requires a prescription from your veterinarian.

For:

Cats and dogs

Benefits:
  • Reduces pressure in the eye due to glaucoma
  • Controls production of fluid, particularly within the eye
  • Reduces risk of nerve damage and loss of vision
How it Works:

Dorzolamide HCl inhibits carbonic anhydrase II. Inhibition of carbonic anhydrase decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure (IOP).

Cautions:

Disclose all medications you are giving to your pet to your veterinarian. If any side effects occur (swelling, hives, difficulty breathing), stop using Dorzolamide HCl on your pet and contact your veterinarian. Do not touch the dropper to any surface, including the eyes and hands. If it becomes contaminated, it could cause an infection in the eye.

Brand Name:

Trusopt (Merck)

Generic Name:

Dorzolamide HCl

What is the most important information I should know about Dorzolamide HCl:

Dorzolamide HCL is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to use this product in dogs and cats. Dorzolamide HCl is available by prescription as a 2% solution in a 10ml sterile ophthalmic dispenser. The usual dose of Dorzolamide HCl is 1 drop in the eye 3 times a day. Do not touch the dropper to any surface, including the eyes and hands. If it becomes contaminated, it could cause an infection in the eye. Dorzolamide HCl may cause blurred vision.

What is Dorzolamide HCl:

Dorzolamide HCl is a carbonic anhydrase inhibitor used to reduce pressure inside the eye by reducing the amount of fluid in the eye. Dorzolamide HCl is used to treat high blood pressure in the eye due to open-angle glaucoma. Dorzolamide HCl may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before using Dorzolamide HCL on my pet:

Tell your veterinarian if your pet has ever had an allergic reaction to a sulfa based drug such as SMZ/TMP (bactrim, Septra), sulfisoxazole, sulfamethoxazole, or sulfacetamide sodium (Bleph-10), Sulamyd Sodium). Dorzolamide HCl is based on a sulfa compound and your pet may have an allergic reaction to it. Tell your veterinarian if your pet has kidney or liver disease. Tell your veterinarian if your pet is pregnant, lactating, or if you intend to breed your pet.

How should this medication be used:

Use Dorzolamide HCl exactly as directed by your veterinarian. If you do not understand these directions, ask your pharmacist or veterinarian to explain them to you. Always wash your hands before and after applying this medication. Apply the medication to the pets eye by pushing on the "Finger Push Area" of the bottle which then releases a single drop of the medication. If you are using another eye drop in your pet, wait 10 minutes between use of different medications. Do not touch the dropper to any surface, including the eyes and hands. If it becomes contaminated, it could cause an infection in the eye. Do not use if the eyedrop is discolored or has particles in it. Store Dorzolamide HCl at room temperature away from moisture and heat. Protect from light. Keep the bottle properly capped.

What happens if I miss a dose:

Apply the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of this medication.

What happens if I overdose the pet:

Symptoms of Dorzolamide HCl overdose are not known but may include panting, diarrhea, vomiting and loss of appetite which can occur when using oral carbonic anhydrase inhibitors. If an overdose is suspected, flush the eye with water and call your veterinarian or veterinary emergency room.

What should I avoid while applying Dorzolamide HCl:

Dorzolamide HCl may cause blurred vision. Do not touch the dropper to any surface, including the eyes and hands. If it becomes contaminated, it could cause an infection in the eye. If you are using another eye drop in your pet, wait 10 minutes between use of different medications.

What are the possible side effects of Dorzolamide HCl:

If any of the following serious side effects occur, stop using this Dorzolamide HCl and seek emergency veterinary medical attention; an allergic reaction (swelling of the lips, face, or tongue; difficulty breathing; closing of the throat; or hives). Less serious side effects may be more likely to occur. Continue to use Dorzolamide HCl and contact your veterinarian if your pet experiences itching or watering of the eye; blurred vision; sensitivity of the eye to sunlight; fatigue; rash; or nausea. Side effects other than those listed here may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.

What other drugs will affect Dorzolamide HCl:

Tell your veterinarian if your pet is being given an oral carbonic anhydrase inhibitor such as acetazolamide (Diamox), dichlorphenamide (Daranide), or methazolamide (Neptazane). Avoid applying other topical medications at the same time unless told to by the veterinarian. Other topical medications may affect the absorption or effectiveness of Dorzolamide HCl. Drugs other than those listed may also interact with Trusopt. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medications, including vitamins, minerals, and herbal products.

Where can I get more information:

Your pharmacist has additional information about Dorzolamide HCl for health professionals that you may read.

Call your veterinarian for medical advice about any side effects to your pet. You may report side effects to the FDA at 1-800-FDA-1088.

How to Use
Directions:
  • Dorzolamide HCl Sterile Ophthalmic Solution is a prescription medication used in dogs and cats to reduce pressure inside the eye by reducing the amount of fluid in the eye.
  • Dorzolamide HCl Sterile Ophthalmic Solution is also used to treat high blood pressure in the eye due to open-angle glaucoma.
  • Dorzolamide HCl Sterile Ophthalmic Solution is a prescription medication not FDA approved for veterinary use; however, it is a commonly accepted practice for veterinarians to prescribe this medication for dogs and cats.
Tip:

Do not touch the dropper to any surface, including eyes and hands. The dropper is sterile. If it becomes contaminated, it could cause an infection of the eye. Do not use if the eye drop is discolored or has particles in it. Dorzolamide HCl Sterile Ophthalmic Solution may cause blurred vision.

Dosage:
Dogs/Cats:
Weight
Dosage
All weights
The usual dose is 1 drop in the eye 3 times a day. Apply this medication to the pet's eye by pushing the 'Finger Push Area" of the dropper bottle which then releases a single drop of the medication. If you are using any other eye drop in your pet's eye, wait 10 minutes between the use of different medications
Horses:
Do not use!
Storage:

Store Dorzolamide HCl Sterile Ophthalmic Solution at room temperature away from moisture and heat. Keep the bottle properly capped.

Ingredients
Dorzolamide HCl:
Active Ingredients (per mL)
Amount
Dorzolamide Hydrochloride
22.3 mg per ml
Benzalkonium Chloride (preservative)
0.0075%
Other Ingredients: Hydroxyethyl Cellulose, mannitol, sodium citrate dihydrate, sodium hydroxide (to adjust pH) and water for injection.
Customer Reviews
Dorzolamide HCL Ophthalmic Solution is rated 3.7143 out of 5 by 7.
Rated 2 out of 5 by from did not help my dog raised the pressure MY VET PUT HER ON IT,THE PRESSURE WAS 28,STARTED IT AND THE INFLUMTION WAS DOWN BUT THE PRESSURE WAS 40
Date published: 2012-12-22
Rated 5 out of 5 by from Oliver is doing good on both items Thank you for asking how Oliver is doing on the 2 items I order. Will be ording more or the Revolution for fee and Hartworm comtrol in a few month. Thanks again Elizabeth
Date published: 2012-12-03
Rated 2 out of 5 by from Warning I found dorzolamide to be effective in reducing pressure in my cat's eyes, but it also caused vomiting and severe anorexia. I observed a direct cause and effect relationship between using dorzolamide and my cat's refusal to eat. Somehow the dorzolamide drains from the eye to the stomach and causes distress. I had to suspend treatment because my cat was starving to death. She required appetite stimulants to get started eating again.
Date published: 2012-02-18
Rated 5 out of 5 by from Great Product My dog Jodi has been using this product for several months. The bulging of her eye has gone down considerably as well as the pain. Her exam is coming up and hopefully we will get a overall improvement by her vet.
Date published: 2011-10-16
Rated 5 out of 5 by from Sydney's eye treatment My bird was suggested to use the Dorzolamide HCL by our Animal Eye Specialist over a year ago. I do apprecite the care and concern showed to me by your company by questioning me about he product that is supposed to be only for dogs and cats but my bird is doing fine on it and the pressure is much better now. She is eating and drinking again. When the pressure was increased she was not eating or drinking she was just sitting around. Now even plays with her toys again. Thanks again for your conern for my little bird Sydney.
Date published: 2011-05-18
Rated 5 out of 5 by from Works Great My dog has been using glaucoma medicine for about a year now. This product works great and has controlled her pressure well. She got a A+ on her last exam!
Date published: 2010-11-03
Rated 2 out of 5 by from Trusopt vs generic The generic bottle is more difficult to use. With the trusopt bottle one could see how much was left, this one is opaque. Also it does not last as long as the trusopt solution as the trusopt has more viscosity.
Date published: 2009-06-08
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Q&A

Can these eyedrops cause brown spots on the cornea of the eye. I don't know if they are blood spots, but look brown on the darkness of his pupil.

He doesn't seem to have any pain, but the white part of his eye is also very red. Any theories on this?
Asked by: SB
Please consult your veterinarian for an eye exam for your pet.
Answered by: Stephanie Duesler, Pharm. D, MBA
Date published: 2015-08-28

How many drops are safe

My dog has been diagnosed with dry eye. This has caused her to develop an ulcer and now she has glaucoma too. It has only been close to 4 weeks since her eye started looking bad and I took her to the vet He has her on Dorzolamide but only 1 drop every 24 hours. Can I give it to her more often. Like every 12 hrs? She is also on Neopolygram every 8 hours. I do wait at least 10 min or longer if drops are to be given around the same time. Would it be safe to give her drops more often? Vet is on vacation for a week so I can't call and ask him Thank you!
Asked by: Laura
Please do not use the medication more often than what is indicated on the prescription. Please consult with your veterinarian upon his or her return to inquire about increasing the frequency of the eye drop.
Answered by: Lilli Pharmacist
Date published: 2014-08-25

How many doses (or drops) are in this container?

Asked by: txdp1978
10 ml bottle same as yours
Answered by: medicine costs
Date published: 2014-01-09

do you have a generic product? I purchased product manufactured by apotex corp at 48.00 or maybe you have this product and i just didn't see it?

Asked by: jock
I have paid up to $100.00 for this product. This company has a great deal for the price. If you paid less that is wonderful
Answered by: Charlie
Date published: 2011-05-20

My pet has normal intraocular eye pressure.

Is it wize to use this to prevent glaucoma?
Asked by: MsMike
I would not use the product to prevent glaucoma. If your pets pressure is normal be happy with that. You should check with your vet before any meds are given to your pet. I would not chance it.
Answered by: Charlie
Date published: 2011-05-20

Dorzolamide and Travatan side effects

My 12 year old poodle is on dorzolamide and travatan for glaucoma. She has become increasingly incontinent and is now having multiple accidents in the house a day. Cushing's Disease and diabetes have been ruled out. Could either of these drugs cause severe bladder control issues?
Asked by: Isabelle's mom
I am not sure if the Dorzolamide is the problem. My sister's dog was doing the same thing as far as incontinance goes and come to find out she has diabetes. You might have her blood sugar checked. My bird is on this product is doing very well. Her stool is soft but I can't tell if she is incontinent.
Answered by: Charlie
Date published: 2011-05-20

how long should this med be used

will using this medicine slow or place the glucoma in remission?
Asked by: reddog
My bird has been using this product for over a year now and has had great results. As for remission I am not sure but It has definitely slowed the glucoma down. She doing very well on it.
Answered by: Charlie
Date published: 2012-04-01

Glaucoma in dogs.

Can glaucoma in dogs be reversed?...... My Basset Hound, around 10 years old, was diagnosed with glaucoma several months ago. She is being treated with Dorzolamide. We try and apply the drops daily, but occasionally miss a day. To date, I have not noticed any improvement. If there's any chance of the reversal of Abigail's glaucoma, then maybe the treatment regimine needs changing. I would greatly appreciate any suggestions, you may offer. I am particularly interested in any information you may have on reversing the glaucoma disease, in dogs. Thanks, David Graybill
Asked by: DGSR
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