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Deramaxx (Click for Larger Image)
 
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Deramaxx

 
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  Product Info   How to use   Ingredients   Customer Reviews   Q & A  

What is Deramaxx?

Deramaxx is used in dogs to control pain and inflammation. Its particularly effective against osteoarthritis, a degenerative disease that affects your dogs joints. It is available as beef-flavored, scored, chewable tablets. Deramaxx requires a prescription from your veterinarian.

For: Dogs
 
Benefits:
Controls pain and inflammation
Effective treatment for canine arthritis, specifically controlling chronic osteoarthritis
Non-steroidal
Comes in a tasty beef-flavored chewable tablet, making administration easy

How it works:
Deramaxx is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the COX-2 inhibitor class of medications. Deramaxx is different from other NSAIDs because at recommended doses it blocks the COX-2 enzyme, not the COX-1 enzyme. While the COX-1 enzyme is necessary for many normal body functions, COX-2 enzymes trigger inflammation and contribute to pain in arthritic joints.

Cautions:
Side effects involving the digestive system, kidneys, or liver may occur. Periodic blood tests may be required.



More Information:
Brand Name
Deramaxx (Novartis)
Generic Name
Deracoxib (der-ah-cox’-ib)

What is the most important information I should know about Deramaxx: Deramaxx is a prescription medication that is FDA approved for use in dogs. Deramaxx is available as 25mg, 75mg, and 100mg chewable, scored tablets. Contact your veterinarian if your pet has hives or an allergic reaction after taking sulfa-based medications such as SMZ/TMP, aspirin, or another NSAID such as Rimadyl. Notify your veterinarian immediately if your pet develops or experiences any of the following: abdominal pain, tenderness or discomfort, nausea, bloody, black, or tarry stools, water retention, fatigue or lethargy, a skin rash, itching, yellowing of the eyes, or unusual bruising or bleeding as these symptoms could be early signs of dangerous side effects. Before giving your pet any prescription or over-the-counter medications, check with your veterinarian or pharmacist.

What is Deramaxx: Deramaxx is a non-steroidal anti-inflammatory drug (NSAID). Deramaxx works by reducing substances that cause pain, inflammation, and fever in the body. Deramaxx is used to reduce pain associated with surgery or dental procedures. Deramaxx is also used for the treatment of inflammation and stiffness as a result of conditions such as arthritis or hip dysplasia. Deramaxx may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving Deramaxx to my pet: Tell your veterinarian if your pet has an allergy to aspirin or any other NSAID, an ulcer or bleeding in the stomach, liver or kidney disease, congestive heart failure, fluid retention, bleeding disorders, heart disease, or high blood pressure. Tell your veterinarian if your pet is pregnant or lactating. Tell your veterinarian if your pet is taking a steroid medication such as prednisone, methylprednisolone, or Prednisolone.

How should this medication be given: Give this medication exactly as directed by your veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. The usual dose of Deramaxx in treating post-operative pain and inflammation is 1.4-1.8mg/pound as a single daily dose. The usual dose of Deramaxx in the treatment of osteoarthritis pain and inflammation is 0.45-0.91mg/pound as a single daily dose. Deramaxx can be given with or without food. Keep plenty of water available for your pet. Store Deramaxx at room temperature, away from moisture and heat. Keep this medication away from children and pets. Do not give Deramaxx to cats.

What happens if I miss giving a dose: Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication.

What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of Deramaxx overdose include drowsiness, nausea, vomiting, stomach pain, headache, blurred vision, little or no urine production, slow breathing, and coma.

What should I avoid while giving Deramaxx to my pet: Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other NSAIDs similar to Deramaxx. Before giving any prescription or over-the-counter medications talk to your veterinarian or pharmacist.

What are the possible side effects of Deramaxx: Contact your veterinarian if your pet has abdominal pain, tenderness, or discomfort, bloody, black or tarry stools, blood in vomit, unexplained weight gain, water retention, fatigue or lethargy, skin rash, itching, yellowing of eyes, or unusual bruising or bleeding as these symptoms could indicate serious side effects. If any of the following serious side effects occur, stop giving Deramaxx and seek emergency veterinary medical attention: an allergic reaction (difficulty breathing, swelling of the lips, tongue or face, or hives). Other less serious side effects may occur. Continue giving Deramaxx and talk to your veterinarian if your pet experiences flatulence or diarrhea, dizziness, headache, or insomnia. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What other drugs will affect Deramaxx: Tell your veterinarian if your pet is being given any of the following: aspirin, another NSAID such as etodolac, carprofen, or piroxicam, an over-the-counter cough, cold, allergy, or pain medication, warfarin, furosemide, an ACE inhibitor such as enalapril, a steroid such as prednisone, insulin, or probenecid. Drugs other than those listed may also interact with Deramaxx. Talk to your veterinarian or pharmacist before giving your pet any prescription or over-the-counter medicines.

Where can I get more information: Your pharmacist has additional information about Deramaxx written for health professionals that you may read.

Directions:
Deramaxx is a non-steroidal anti-inflammatory drug (NSAID) belonging to the COX-2 inhibitor class of medications. Deramaxx is a prescription product, and is for dogs only.
Deramaxx is a beef-flavored chewable tablet and works by reducing substances that cause pain, inflammation, and fever in the body.
Deramaxx is used to treat pain associated with surgery or dental procedures. Deramaxx is also used for the treatment of inflammation and stiffness as a result of conditions such as arthritis or hip dysplasia.
Tip: Deramaxx can be given with or without food. Keep plenty of water available for your pet
to drink.
Dosage:

Pet Weight Dosage
Dogs: (to treat post-operative pain and inflammation) 4 lbs and over 1.4-1.8mg per pound as a single daily dose. Do not give for more than 7 days
Dogs: (to treat osteoarthritis pain and inflammation) All weights 0.45-0.91mg per pound as a single daily dose
Cats:
Horses:

Storage: Store this product at room temperature away from moisture and heat.

Deramaxx:
Active Ingredients Amount
Deracoxib 25 mg

Deramaxx:
Active Ingredients Amount
Deracoxib 75 mg

Deramaxx:
Active Ingredients Amount
Deracoxib 100 mg

Deramaxx 4.6 5 278 279
Deramaxx My 3 year old Great Pyrenees could not get up, he is 200 lbs so I couldn't do much. The vet had me try Deramaxx. To start he took 2 100mg tablets but after a week we switched to 1 tablet. He can now go outside and move around! The only other option was not a good one! 04/03/2011
Deramaxx Big change in my 7 year old Westie, Mr. Benny. He's still skitish about jumping up on the couch or the bed - but he's jumping down without a hitch, and he's coming up the back stairs perfectly. Thank you Pet-meds! 03/16/2011
Deramaxx This close relative of the human arthritic drug celebrex, which has helped so many suffering human arthritis patients, has really shined in its veterinary use. All nonsteroidal anti inflammatory drugs on the market to varying degrees block enzymes in our pets bodies involved with pain and inflammation. The deramaxx difference and advantage is that unlike many competitor products, deramaxx does NOT block enzymes that are involved in blood clotting, protection of the stomach lining and kidney function, thus providing an increased balance of safety and efficacy over other products I have seen in practice. Deramaxx specifically targets the source of osteoarthritis inflammation and pain with ONE chewable tablet controlling inflammation for a full 24 hours. This FDA approved drug has been prescribed to over one million dogs over the past 2 years. One study with one of its major competitors, showed that lame dogs put more weight on the leg quicker and for longer periods than another drug of its class commonly prescribed. As with any individual drug of the nonsteroidal anti inflammatory class, there can be very rare reactions involving the digestive tract, kidneys or liver. I find that when we do complete blood and urine workups on pets before starting on this medication, that we are able to prescribe drugs like this more safely. For those pets who need deramaxx long term, blood work should be done every 4-6 months in my opinion. I often find that when using the wonderful neutraceuticals from 1800petmeds for arthritis like super joint enhancer, proanthozone, and super joint omega that I am able to use much lower doses of deramaxx in controlling chronic degenerative joint disease and arthritis in many of our aging dogs,, even only a dose or two a week in some cases, once the neutraceuticals take effect over several weeks. For some of the major orthopedic procedures done on dogs today, including fracture repair, joint reconstruction, and the ever increasing number of cruciate surgeries being done on dogs, that deramaxx offers superior relief and quicker return to function than some of the other competitor products. The main disadvantages I have found is the lack of an approved injectable medication for same day use in my surgery cases, as well as the lack of FDA labelled safety and approval for use in young puppies.6 weeks of age. Also it is so important for clients to review with their veterinarians any prior drug or antibiotic reactions, ot the use of any other over the counter drugs, other prescription medicines, as well as nutritional supplements that could interact with drugs of this class and potentially lead to increased complications. These issues should always be discussed with your vet on case by case basis, but by no means should discourage the use of this wonderful often life saving drug.. 06/13/2008
Deramaxx has been a wonderful product for our female mixed breed dog. She is able to play ball and be active again. Before she was crying and whimpering when she even drank water, laid down or got up. Thank you 06/05/2013
IT Works Wonders for my old dog ! I have ask the Vet for some drug to give my female 14 year old Scottish terrier who has front paw problems. She gave me Deramaxx and the dog weighs 20# and she tells me to give her 1/2 of a 25mg tablet each day I give it to her. She tells me not to give it everyday, and I don't. the tablet has a line down it, so splitting the tablet is easy. my dog eats it right up, and in an hour or less, she is like a young dog again! it lasts about 12 hours, and that is about how active my dog is around the house. she is near the end of her life span, and im glad she is not in pain using Deramaxx. I am glad to know she can still enjoy life with us, until she just lays down and passes away someday in peace. I will know I did make her life more enjoyable and less painful, since no one or no animal lives forever. 06/03/2013
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82 Questions · 141 Answers

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2 months ago
by
Rick
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Answer: 
Please consult with your veterinarian.
2 months ago
by
Lilli Pharmacist
Pompano Beach, FL
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Everyone that has used Deramaxx including myself has seen incredible improvement, however, what do we use now, since we cannot order this anymore. I have tried all that you say is compatible and nothing has helped.
6 months ago
by
Anonymous
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Answer: 
The other one a different vet wanted us to use was Rimadyl and it is supposed to be very effective as well. Talk to your Vet and see what they say for your animal.
1 week, 5 days ago
by
Puppy
Ramona, CA
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Answer: 
we still occasionally get a few bottles of deramaxx into stock. Please check with us every couple of weeks.
6 months ago
by
Linda M 1800petmeds pharmacist
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My dog has had a bad reaction to Piroxicam (vomiting and diarrhea) and Deramaxx (loss of appetite - I quit before it could get any worse G-I-wise). These NSAIDs really helped with her mobility but she could not tolerate them. Which NSAIDs are considered the easiest on the G-I system? (She is being treated for bone cancer.)
1 year, 2 months ago
by
Deb
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Answer: 
I am so sorry to hear your dog has bone cancer. Our dog seems to only take the Deramaxx if in cheese, but we give her at a separate time of the day Canine Flex Plus which is liver based for her joints and Hyla Flex 10 for large dogs which is a Hyaluronic Acid on a little dry food mixed with warm water. Also, when giving the Deramaxx I know the vet suggested we give her an Acid controller like Pepcid. I hope you find something that will alleviate your dogs pain. Good luck
1 week, 5 days ago
by
Puppy
Ramona, CA
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Answer: 
I am terribly sorry to hear about your dog's bone cancer. To answer your question I reached out to one of our staff pharmacist. He shared with me this answer: The Cox-2 non-steroidals like Deramaxx and Previcox are easier on the gastrointestinal tract than the older non-steroidals like Rimadyl.
1 year, 2 months ago
by
Laura, PetMed Pro
Pompano Beach, Florida
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1 year, 2 months ago
by
Anonymous
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Answer: 
My vet said today that it is not known when Deramaxx will be available from Novartis.
1 year ago
by
Lin
Boynton Beach, FL
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Answer: 
At this time they have not given any information as to when it will reopen. We will have the most recent information on Novartis products on the products information pages. We are getting small supplies of various Novartis products so please check back often.
1 year, 2 months ago
by
Laura, PetMed Pro
Pompano Beach, Florida
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1 year, 2 months ago
by
mocha
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Answer: 
Although specific drug interactions haven't been noted with Demarax (Deracoxib), it is always recommeded the careful use of herbal medications. Many herbal products can either increase or decrease the amount of other medications in the body causing serious problems. Devil's claw might increase the effects and side effects of some medications by decreasing the break down of those medications in the liver. Always consult your veterinarian before using any over-the-counter products including herbals if your pet is on a prescription medication.
1 year, 2 months ago
by
Yoliset, Student Pharmacist
Pompano Beach
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Product Q&A

82 Questions | 141 Answers
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This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies.
 
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