Denamarin is a nutritional supplement containing the antioxidant Silybin used to improve your pet's liver function by increasing liver glutathione levels. The tablets come in three different strengths; for cats and small dogs, for medium dogs, or for large dogs.
Supports healthy liver function by raising antioxidant levels
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Silybin aids digestion and absorption of nutrients from your pet's diet
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No known side effects
How it works:
Denamarin combines a pure S-Adenosylmethionine (SAMe) with silybin to provide a one-two punch to keep your pets liver healthy. Silybin supports the flow of bile through the liver which helps with the digestion and absorption of nutrients from your pet's diet. Silybin also helps to regenerate liver cells and may enhance levels of glutathione, an antioxidant that helps to protect cells from toxins such as free radicals.
Cautions:
Store in a cool dry place.
More Information:
Brand Name Denamarin
Active Ingredient(s): S-Adenosylmethionine, Silybin A+B
What is this product used for: Denamarin for dogs and cats is a patented nutritional supplement for veterinary use in dogs and cats. Denamarin combines a pure and stabilized S-Adenosylmethionine with Silybin to provide a multi-faceted approach to liver support.
Availability: Denamarin is a non-prescription (OTC) product available in blister pack boxes of 30 for small dogs and cats (90mg/9mg), medium dogs (225mg/24mg) and large dogs (425mg/35mg).
How this product should be used: For small dogs and cats up to 12 pounds give 1 tablet of the small size. For medium dogs 13 to 34 pounds give 1 tablet of the medium size. For large dogs 35 to 65 pounds give 1 tablet of the large size. For large dogs 66 to 120 pounds give 2 tablets of the large size, and for large dogs over 120 pounds give 3 tablets of the large size. The tablets should be given on an empty stomach at least one hour before a meal for optimal absorption, typically one hour before feeding in the morning. For owners who find it difficult to administer tablet(s) to their pets, Denamarin may be disguised in a small bite of food. The number of tablets administered may be gradually reduced, or increased, at any time at the recommendation of your veterinarian. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.
What are the side effects: There are no known side effects.
What special precautions are there: This product is for veterinary use in dogs and cats only.
In the event of overdose: Contact your veterinarian or veterinary emergency room.
How should I store this product: Store in a cool dry place. Keep tablets in the original blister pack until used.
Directions:
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Denamarin contains S-adenosylmethionine (SAMe) and Silybin, the most active part of an extract from milk thistle.
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Denamarin helps protect liver cells and may help cell repair and regeneration.
•
Denamarin is a non-prescription product available in blister pack boxes of 30 for cats and small dogs, medium dogs, and large dogs.
Tip: The tablets should be given on an empty stomach at least one hour before a meal for optimal absorption, typically one hour before feeding in the morning. For owners who find it difficult to administer tablet(s) to their pets, Denamarin may be disguised in a small bite of food. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.
Dosage:
Pet
Weight
Dosage
Dogs:
Under 12 lbs
Give 1 tablet of the small size tablet daily
13-34 lbs
Give 1 tablet of the medium size tablet daily
35-65 lbs
Give 1 tablet of the large size tablet daily
66-120 lbs
Give 2 tablets of the large size tablet daily
120 lbs and over
Give 3 tablets of the large size tablet daily
Cats:
All weights
Give 1 tablet of the small size tablet daily
Horses:
Storage: Store in a cool dry place. Keep tablets in the original blister pack until used.
Denamarin for Cats and Small Dogs up to 12 lbs:
Active Ingredients (per tablet)
Amount
S-Adenosylmethionine
90 mg
Silybin A+B
9 mg
Denamarin for Medium Dogs 13 to 34 lbs:
Active Ingredients (per tablet)
Amount
S-Adenosylmethionine
225 mg
Silybin A+B
24 mg
Denamarin for Large Dogs 35 lbs and over:
Active Ingredients (per tablet)
Amount
S-Adenosylmethionine
425 mg
Silybin A+B
35 mg
Denamarin Tabs
4.8
5
27
27
Large Dog
Our dog, Toothpick, finally lived up to her name. She is a 13 year old mix who has always been very active but, "Mom" was scolded by the vet because she was overweight on more than 1 occasion. Then, in 2009, she was diagnosed with a tumor and had to have her spleen removed. She recovered but, then was diagnosed with thyroid disease not long afterwards. She initially lost weight after her surgery and then once she was put on thyroid meds, she lost even more weight and became gaunt looking, with protruding bones. However, the vet said her bloodwork looked good so, we let it be. A couple of weeks ago, we decided she was just too thin and went back and insisted on more tests. $900 later, we now know her liver is enlarged and her liver panel came back with really bad numbers. The vet wants to do ultrasounds and biopsy anything they find (another $900) but, even if they find liver disease or cancer, how much do you put a 13 year old dog through, hoping only to prolong the inevitable? The vet put her on the Denamarin and antibiotics and after 3 weeks, she seems to be gaining a small amount of weight. I decided to order more Denamarin from Pet Meds for the price savings. After reading the other reviews, I have more hope than I have had in the last month! Thank you all for sharing your pets' success and stories! I will enjoy what time I have left with her and stop thinking she's going "any minute" now and try to think more positively about it all!
10/20/2011
Wonderful!
My greyhound had a serious adverse reaction to Doxicycline and nearly died. Her liver values (ALT) were over 10,000. Our vet school treated her for weeks and denamarin was part of the meds that she was given. It worked beautifully and we still give it to her to support her liver. I think this medicine helped to save her life!
07/31/2011
Shasta on the mend
It all started with her thowing up bile constantly and a stinky diahrea. Off to the vet - very elevated liver enzymes indicative of an infection - upshot researched SAM-E so she was on that and the antibiotics for three months. then she was fine for about 4 months when she started throwing up bile again. Quickly restarted the SAM-E and now no problems - I expect she will be on it for life. She gets it in the AM before I feed the her.
Be sure to give it to you fur friend fasting before and at least an hour after for the absorption to occur properly. And don't take it out of the foil seal until you are ready to give it. SAM-E is hydroscopic and will start to absorb moisture from the air and break down quickly if you do.
07/22/2011
Feels better at almost 16...
i have always called my dog the Energizer Bunny. I asked a vet once if I should get another dog to calm her down and she replied "you know how sometimes a party doesn't stop 'til that one person shows up. That's your dog." About a year ago, she dropped weight after a bout of a tick borne disease. She's always been trim and energetic but she was losing muscle mass. The blood work was fine up until about a month ago when she wouldn't eat and this dog never passed up table food and she was refusing ham and chicken etc. Get the blood work back, elevated liver enzymes, Xray showed enlarge round liver. After a 3 day stay of IV fluids (to help rid herself of toxins. My idea not the vet's suggestion), a course of antibiotics for both aerobic (oxygen dependent bacteria) and anaerobitic (non-oxygen dependent) bacteria, and the Denamarin. She is eating. HATED the LD diet ( looks terrible and is hard as a rock) likes the Salmon Chicken Blue Wilderness soft food. I also went back to an old favorite of hers: Mother Hubbard Peanut Butter cookies ( the small ones for easier chewing). Vet recommended low protein diet but she won't eat anything but this and the stinky whitefish catfood (low magnesium but still not ideal for the dog). For those of you that are struggling with "I'll eat one bite but not two," my dog was doing that too but don't lose heart. She hasn't vomited in a couple of weeks and her little system on the other end is adjusting (soft stool and some diarrhea) but it's better than that look "Feed me I'm hungry" look and then the turned nose and a "no, thanks." She's in three weeks and barring any episodes, I won't be going back to the vet for another week or two...hope this was helpful...PS. she gained one pound at 31 hoping to get back to 35-40lbs. jo
07/05/2011
Miracle Drug!
Miracle Drug!
Our Golden 18 months ago after $3K in tests, was given weeks to live and cancer in his liver. Our vet gave him Denamarin, antibiotics, and protein only diet. He is still with us a doing great! The vet calls him the miracle dog and to change nothing we are doing as his blood work 3 mo ago showed a normal 8 yr old....only his weight is a bit under normal, all else is great. If we ever run out of Denamarin for more then 2 days, we can tell in our dog.....it really works!
07/03/2011
Denamarin for Cats and Small Dogs is made so that a pet 12 pounds or less can easily take the product. While you cannot break or crush the tablet, you can place it in a very small amount of food to make it easier to give to the pet.
Golden 65lbs takes Denamarin but has difficulty swallowing pill whole w/o chewing. I can get her to cooperate if I coat it in a teaspoon of PB, however, does this interfere with the empty stomach requirement?
Tip: The tablets should be given on an empty stomach at least one hour before a meal for optimal absorption, typically one hour before feeding in the morning. For owners who find it difficult to administer tablet(s) to their pets, Denamarin may be disguised in a small bite of food. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.
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