FREE Shipping on orders over $49
15% OFFCoupon Code:
SAVE15
100% Satisfaction Guaranteed
 15% OFF w/code
SAVE15
FREE Shipping $49+
100% Satisfaction Guaranteed
My Account
Errors:

Advantage Multi

Rx Info
1. We'll ask for your vet's info during checkout.
2. We verify your prescription and ship your order!
Close
Starts $116.24 $81.99 
Ships in one business day or less
1
Select Pet's Weight:
Dog
03-09 lbs
09-20 lbs
20-55 lbs
55-88 lbs
88-110 lbs
Cat
05-09 lbs
09-18 lbs
2
Select a Supply:
6 pack
$116.24
$96.46
$81.99
Price w/coupon SAVE15
Free Shipping
12 pack
$218.73
$179.98
$152.98
Price w/coupon SAVE15
Free Shipping
Save $10 over 6 pk
Starts $116.24 $81.99 
Ships in one business day or less
Please select all product options.
3
Select a Quantity:
Quantity
Please select all product options.
Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Advantage Multi?

Advantage Multi is a once-a-month topical application that protects dogs, cats, and ferrets against heartworms, fleas, and multiple other parasites. It contains a combination of the insecticide imidacloprid and the parasiticide moxidectin. Advantage Multi for Dogs is used for the prevention of heartworm disease, as well as the treatment and control of flea infestations, hookworms, roundworms, whipworms, and sarcoptic mange. Advantage Multi for Cats is used for the prevention of heartworm disease, as well as the treatment and control of flea infestations, roundworms, hookworms, and ear mites. Advantage Multi for Cats is also the first and only approved product to kill adult fleas, treat flea infestations, and prevent heartworm disease in ferrets. Advantage Multi requires a prescription from your veterinarian.

NOTE: Advantage Multi does not protect against ticks. For additional 8 months of protection against fleas and ticks in dogs and cats, use the Seresto Collar.

For:

Dogs (7 weeks of age or older, weighing 3+ lbs), Cats (9 weeks of age or older, weighing 2+ lbs), Ferrets (weighing 2+ lbs)

Benefits:
  • Prevents heartworms, hookworms, roundworms, whipworms, and sarcoptic mange in dogs
  • Prevents heartworms, hookworms, roundworms, whipworms, and ear mites in cats
  • Kills adult fleas and treats flea infestations in both dogs and cats
  • Prevents heartworm disease, kills adult fleas, and treats flea infestations in ferrets
  • Easy, once-a-month topical application
  • Use the Seresto Collar (sold separately) for 8 months of additional protection against fleas, flea eggs, flea larvae, and ticks
How it Works:

The active ingredient moxidectin is used for the prevention and control of heartworms and intestinal worms by disrupting nerve transmission resulting in the paralysis and death of the parasite. The active ingredient imidacloprid, acts on the nervous system of the flea to cause paralysis and subsequent death.

Cautions:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become severe, consult a veterinarian immediately. Safety has not been established in breeding, pregnant, or lactating dogs. Not for human use. Keep out of the reach of children. Children should not come in contact with application sites for two (2) hours after application. Causes eye irritation. Harmful if swallowed. Do not get in eyes or on clothing. Avoid contact with skin. Exposure to the product has been reported to cause headache; dizziness; and redness, burning, tingling, or numbness of the skin. Wash hands thoroughly with soap and warm water after handling. If contact with eyes occurs, hold eyelids open and flush with copious amounts of water for 15 minutes. If eye irritation develops or persists, contact a physician. If swallowed, call a poison control center or physician immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by the poison control center or physician. People with known hypersensitivity to benzyl alcohol, imidacloprid or moxidectin should administer the product with caution. In case of allergic reaction, contact a physician. If contact with skin or clothing occurs, take off contaminated clothing. Wash skin immediately with plenty of soap and water. Call a poison control center or physician for treatment advice.

Brand Name:

Advantage Multi (Bayer)

Generic Name:

Imidacloprid, Moxidectin

What is the most important information I should know about Advantage Multi for Dogs and Cats:

Advantage Multi for Dogs is available in the following concentrations; Advantage Multi 9 containing imidacloprid 40 mg and moxidectin 10 mg in 0.4 ml tubes for dogs 3-9 lbs, Advantage Multi 20 containing imidacloprid 100 mg and moxidectin 25 mg in 1 ml tubes for dogs 9.1 to 20 lbs, Advantage Multi 55 containing imidacloprid 250 mg and moxidectin 62.5 mg in 2.5 ml tubes for dogs 20.1-55 lbs, Advantage Multi 88 containing imidacloprid 400 mg and moxidectin 100 mg in 4 ml tubes for dogs 55.1 to 88 lbs, and Advantage Multi 110 containing imidacloprid 500 mg and moxidectin 125 mg in 5 ml tubes for dogs 88.1 to 110 lbs. For dogs over 110 lbs, use the appropriate combination of Advantage Multi for Dogs tubes. Advantage Multi for Cats is available in the following concentrations; Advantage Multi 5 containing imidacloprid 23 mg and moxidectin 2.3 mg in 0.23 ml tubes for cats 2 to 5 lbs, Advantage Multi 9 containing imidacloprid 40 mg and moxidectin 4 mg in 0.4 ml tubes for cats 5.1 to 9 lbs, and Advantage Multi 18 containing imidacloprid 80 mg and moxidectin 8 mg in 0.8 ml tubes for cats 9.1 to 18 lbs. For cats over 18 lbs, use the appropriate combination. Children should not come in contact with the application site for two (2) hours after application.

What is Advantage Multi:

Advantage Multi contains a combination of insecticide (imidacloprid) and endectocide (moxidectin). Advantage Multi for Dogs is used for the prevention of heartworm disease and the treatment and control of flea infestations, hookworms, roundworms, whipworms, and sarcoptic mange in dogs. Advantage Multi for Cats is used for the prevention of heartworm disease and the treatment and control of flea infestations, roundworms, hookworms, and ear mites in cats. Advantage Multi for Cats is now also the first and only product indicated to kill adult fleas, treat flea infestations, and prevent heartworm disease in ferrets.

What should I discuss with my veterinarian before applying Advantage Multi for Dogs and Cats:

Tell your veterinarian if your pet is breeding, pregnant or lactating since safe use of this product in these cases has not been determined. Do not use in pets that are allergic to Advantage Multi or either of the individual ingredients, imidacloprid (Advantage II, K9 Advantix II) or moxidectin.

How should this medication be used:

Advantage Multi is applied topically to the skin. It is not given by mouth. Follow the manufacturer's directions for application. Do not apply to irritated skin. Apply each dose once a month, every 30 days. If you do not understand the directions, or if you have difficulty applying the medication, contact your pharmacist or veterinarian. Store Advantage Multi at temperatures between 39° F and 77° F, avoiding excess heat or cold.

What happens if I miss giving a dose:

Apply the missed dose as soon as you remember. If it is almost time to apply the next dose, skip the missed dose and apply the next dose as directed. Do not apply 2 doses at once.

What happens if I overdose the pet:

Seek emergency veterinary medical treatment. Symptoms of overdose may include depression, increased salivation, tremors, or incoordination.

What should I avoid when applying Advantage Multi for Dogs and Cats:

Always follow the dosage instructions provided by your veterinarian. Do not use in dogs under 7 weeks of age or less than 3 lbs. Do not use in cats under 9 weeks of age or less than 2 lbs. Do not use Advantage Multi for Cats in ferrets under 2 lbs. Do not use on pets that are sick, debilitated, or underweight. Do not use Advantage Multi for Dogs on a cat. Do not use Advantage Multi for Cats on a dog. Do not allow any pet to lick the application site for 30 minutes. Separation of treated pets may be necessary. Children should not come in contact with the application site for 30 minutes after application. Advantage Multi can cause eye irritation and be harmful if swallowed. Wash hands thoroughly with soap and water after handling.

What are the possible side effects of Advantage Multi Dogs and Cats:

If any of the following serious side effects occur, stop using Advantage Multi and seek emergency veterinary medical attention: an allergic reaction (facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma). Contact your veterinarian if your pet shows scratching, rubbing, licking the application site, lethargy, decreased appetite, or hyperactivity. Contact your veterinarian if your pet shows lethargy and prolonged periods of sleep, behavioral changes including agitation, excessive grooming, hiding, pacing, etc., discomfort at the application site (rubbing, scratching, etc.), increased salivation within 1 hour of treatment, increased drinking, or coughing. A medicinal odor and residue at the application site may also be noticed. Ingestion of this product by pets may cause serious adverse reactions including depression, salivation, dilated pupils, incoordination, panting, and generalized muscle tremors. In avermectin sensitive pets, the signs may be more severe and may include coma and death. Hair may appear stiff, matted oily, or damp after application. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What other drugs will affect Advantage Multi for Dogs and Cats:

Talk to your veterinarian or pharmacist regarding any other medications, including vitamins and supplements, as well as other flea and tick products your pet is using.

How to Use
Directions:
  • Advantage Multi for Dogs and Advantage Multi for Cats are prescription medications used for the prevention of heartworm disease.
  • Advantage Multi for Dogs is also used in dogs for the treatment and control of flea infestation, hookworms, roundworms, whipworms, and sarcoptic mange.
  • Advantage Multi for Cats is also used in cats for the treatment and control of flea infestation, roundworms, hookworms, and ear mites.
  • Advantage Multi for Cats is also the first and only approved product to kill adult fleas, treat flea infestations, and prevent heartworm disease in ferrets.
  • Do not use Advantage Multi for Dogs on cats or ferrets.
  • Do not use Advantage Multi for Cats on dogs.
  • Do not administer this product orally.
Application instructions for Advantage Multi for Dogs:
  1. Remove one dose applicator tube from the package. As specified below, administer the entire contents of the Advantage Multi for Dogs tube that correctly corresponds with the body weight of your dog.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. Your dog should be standing for application. Part the hair on the back of your dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of your dog.
Application instructions for Advantage Multi for Cats:
  1. Remove one dose applicator tube from the package. Administer the entire contents of the Advantage Multi for Cats tube.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. FOR CATS: Part the hair on the back of your cat's neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube. FOR FERRETS: Part the hair on the back of your ferret's neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube. NOTE: Only Advantage Multi 9 should be used on ferrets.
Tip:

For the first 30 minutes after application, ensure that dogs and cats cannot lick the product from the application sites on themselves or other treated pets. Separate treated pets from one another and from other pets to reduce the risk of accidental ingestion. Wash hands with soap and water after handling. Do not let children touch the treated pet's skin for at least 30 minutes after applying the product. Do not get these products in your pet's mouth or eyes.

Dosage:
Dogs/Puppies: (7 weeks of age or older)
Weight
Dosage
3-9 lbs
While your dog is standing, apply Advantage Multi 9 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
9.1-20 lbs
While your dog is standing, apply Advantage Multi 20 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
20.1-55 lbs
While your dog is standing, apply Advantage Multi 55 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
55.1-88 lbs
While your dog is standing, apply Advantage Multi 88 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
88.1-110 lbs*
While your dog is standing, apply Advantage Multi 110 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
Cats/Kittens: (9 weeks of age or older)
Weight
Dosage
2-5 lbs
Apply Advantage Multi 5 for Cats topically according to the above instructions. Apply each dose once every 30 days.
5.1-9 lbs
Apply Advantage Multi 9 for Cats topically according to the above instructions. Apply each dose once every 30 days.
9.1-18 lbs**
Apply Advantage Multi 18 for Cats topically according to the above instructions. Apply each dose once every 30 days.
Ferrets:
Weight
Dosage
2-4.4 lbs
Apply Advantage Multi 9 for Cats topically according to the above instructions. Apply each dose once every 30 days.
Horses:
Do not use!
Storage:

Should be stored at room temperature between 39° F and 77° F, avoiding excess heat or cold.

*For dogs over 110 lbs use the appropriate combination.

**For cats over 18 lbs use the appropriate combination.

Ingredients
Advantage Multi 9 for Dogs 3-9 lbs:
Active Ingredients
Amount
Imidacloprid
40 mg
Moxidectin
10 mg
Advantage Multi 20 for Dogs 9.1-20 lbs:
Active Ingredients
Amount
Imidacloprid
100 mg
Moxidectin
25 mg
Advantage Multi 55 for Dogs 20.1-55 lbs:
Active Ingredients
Amount
Imidacloprid
250 mg
Moxidectin
62.5 mg
Advantage Multi 88 for Dogs 55.1-88 lbs:
Active Ingredients
Amount
Imidacloprid
400 mg
Moxidectin
100 mg
Advantage Multi 110 for Dogs 88.1-110 lbs:
Active Ingredients
Amount
Imidacloprid
500 mg
Moxidectin
125 mg
Advantage Multi 5 for Cats 2-5 lbs:
Active Ingredients
Amount
Imidacloprid
23 mg
Moxidectin
2.3 mg
Advantage Multi 9 for Cats 5.1-9 lbs:
Active Ingredients
Amount
Imidacloprid
40 mg
Moxidectin
4 mg
Advantage Multi 18 for Cats 9.1-18 lbs:
Active Ingredients
Amount
Imidacloprid
80 mg
Moxidectin
8 mg
Customer Reviews
Advantage Multi is rated 4.1 out of 5 by 258.
Rated 4 out of 5 by from Great product I recently purchased Advantage Multi for the first time and so far I am pleased with how quickly I got the product from 1-800petmeds and how well it is working for my dog so far :)
Date published: 2017-03-09
Rated 5 out of 5 by from Great product! I usually purchase this product from a Vet but I moved to another state and my current Vet didn't carry it. First time ordering through 1800petmeds and it was easier than I expected. Received product much faster than anticipated. Excellent service!
Date published: 2017-03-05
Rated 5 out of 5 by from Ease of use Paige has been on this medication for several yes. But vet ceased to carry it, glad I found pet meds.
Date published: 2017-02-28
Rated 5 out of 5 by from Great product I use this product for both my cat and dog and have never had a problem. I love that it covers both flea and heatworms since that means I don't have to buy two different products. We have used this product since adopting our first pet and although the dog usually gets a flea or two right as the month is ending it is nothing serious, just time for a new dose. The cat and dog packaging is exactly alike except for the picture, so be careful if applying to different pets at the same as to not mix them up.
Date published: 2017-02-25
Rated 5 out of 5 by from Works great! In only two doses the ear mites were gone! Great customer service.
Date published: 2017-02-13
Rated 5 out of 5 by from Very pleased! Being able to purchase the heartworm/flea meds online at a very good price will keep me coming back to 1800 PetMeds. Thank you.
Date published: 2017-02-09
Rated 5 out of 5 by from Love advantage multi! I have always used advantage multi....everytime I use it where ever my cats sit I turn a flashlight on in their area and see fleas just dying...this stuff works awesome..this pic was a couple from couch and what was on our comforter from 830 and to 1230
Date published: 2017-01-17
Rated 5 out of 5 by from Very Happy with 1800-Pet service I order multi advan. for my pup making the order was easy, it was delivered when expected and I will be using 1800-Pet in the future
Date published: 2017-01-11
  • y_2017, m_3, d_21, h_15
  • bvseo_bulk, prod_bvrr, vn_bulk_1.0.0
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_258
  • loc_en_US, sid_prod10945, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_1800petmeds
Q&A

Can Advantage II be applied on a dog where Vectra is also being applied

Asked by: Jennifer
We advise to please consult your veterinarian as this may be too much medication at one time.
Answered by: Amy Petmed Pro
Date published: 2017-03-14

Is this waterproof? I normally run a wet flea comb with dawn dish soap and I want to know if doing that will lessen the effect of the medicine.

Asked by: mayra
Yes, this is waterproof. You should wait at least 1-2 hours though after application before your pet gets wait. Also make sure they do not lick themselves or have human contact at least 30 minutes after application. Hope this helps.
Answered by: Trey W
Date published: 2017-03-13

My cat is 9 lbs. When should I move up to the higher dose?

Asked by: Stephanie
Technically the next recommended dose is at 9.1lbs. Consult with your veterinarian on if the switch is necessary.
Answered by: Ben B
Date published: 2017-02-22

I have multiple dogs on the product advantage muti it works great. I want supply on hand all the time for the price it's a great online for the product but do you accept Care credit for payment it would be a great advantage to have on hand

Asked by: Shawna
Contact customerservice@1800petmeds.com via email or call customer service via 1-800-Petmeds. They can further assist you.
Answered by: Ben B
Date published: 2017-02-21

Can I use advantage multi on my cat every 14 days?   The ear mite infection has returned--two weeks after I dosed her

Asked by: Cynthia
Hello, Advantage multi is only approved for application every thirty days. The medication should run out its course, especially if this is the first time your using this product. If you have been using this product for months I would talk to your veterinarian about possibilities of switching medications. Thanks for asking, Pharmacy Intern
Answered by: Ben B
Date published: 2017-02-17

My dog has fleas and I applied the medicine. Do I need to apply another treatment? If so, what? 

Asked by: MMC1
Hello, You do not need another dose and should not apply another treatment until the next scheduled dose, which is every thirty days. The drug is FDA approved to treat and control fleas with this dosing regimen. Thanks for asking, Pharmacy Intern
Answered by: Ben B
Date published: 2017-02-17

I put Advantage Multi on my adult dog in the am. That afternoon he got in the pond behind the house. A week later I found a tick embedded in his skin. When should I reapply?

Asked by: Jennyppi
First, Advantage Multi does not kill ticks. The heartworm prevention part has most likely done it's job for the month during the first 12 hours after application. The single swim in the pond that afternoon may slightly decrease the flea control part but not totally eliminate it. Apply the next dose at the regularly scheduled time and perhaps get a tick collar, such as Preventic, to control the ticks.
Answered by: SuzyCVT
Date published: 2017-02-17

Gave our 3 cats this treatment December 12 and just now able to get the next dose. They are always inside. Our vet says if they miss a month, 30 days they will need an office visit and test. What is your recommendations?

Asked by: Dales
It takes 6 months from the date of infection for a heartworm test to show a positive result. Missing only one month should not require retesting before the next dose is used, and you should continue monthly dosing to prevent potential infection. Your vet does have the right to require a test in 6 months after the missed dose.
Answered by: SuzyCVT
Date published: 2017-02-17
  • y_2017, m_3, d_21, h_15CST
  • bvseo_bulk, prod_bvqa, vn_bulk_1.0.0
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_263
  • loc_en_US, sid_prod10945, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_1800petmeds
Close
Share Website Feedback
Name:
Email:
Phone:
Feedback: