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Advantage Multi

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Starts $116.24 $83.69 
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20-55 lbs
55-88 lbs
88-110 lbs
Cat
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09-18 lbs
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$218.73
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Advantage Multi?

Advantage Multi for is a once a month topical application that contains a combination of the insecticide (imidacloprid) and the parasiticide (moxidectin). Advantage Multi for Dogs is used for the prevention of heartworm and the treatment and control of flea infestations, hookworms, roundworms and whipworms. Advantage Multi for Cats is used for the prevention of heartworm and the treatment and control of fleas infestations, roundworms, hookworms and ear mites. Advantage Multi for Cats is also the first and only approved product to kill adult fleas, treat flea infestations and prevent heartworm disease in ferrets. Advantage Multi requires a prescription from your veterinarian.

For:

Dogs (7 weeks of age or older and weighing at least 3 lbs), Cats (9 weeks of age or older and weighing at least 3 lbs), Ferrets (weighing at least 2 lbs)

Benefits:
  • Prevents heartworms, roundworms, hookworms in dogs and cats as well as whipworms in dogs and ear mites in cats
  • Prevents heartworm disease, kills adult fleas and treats flea infestations in ferrets
  • Easy, once a month, application
  • Canine customers often purchase Preventic collars (sold separately) for tick protection
How it Works:

The active ingredient moxidectin is used for the prevention and control of heartworms and intestinal worms by disrupting nerve transmission resulting in the paralysis and death of the parasite. The active ingredient imidacloprid, acts on the nervous system of the flea to cause paralysis and subsequent death.

Cautions:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become severe, consult a veterinarian immediately. Safety has not been established in breeding, pregnant, or lactating dogs.

Brand Name:

Advantage Multi (Bayer)

Generic Name:

Imidacloprid, Moxidectin

What is the most important information I should know about Advantage Multi for Dogs and Cats:

Advantage Multi for Dogs is available in the following concentrations; Advantage Multi 9 containing imidacloprid 40mg and moxidectin 10mg in 0.4ml tubes for dogs 3-9 lbs, Advantage Multi 20 containing imidacloprid 100mg and moxidectin 25mg in 1 ml tubes for dogs 9.1 to 20 lbs, Advantage Multi 55 containing imidacloprid 250mg and moxidectin 62.5mg in 2.5ml tubes for dogs 20.1-55 lbs, Advantage Multi 88 containing imidacloprid 400mg and moxidectin 100mg in 4 ml tubes for dogs 55.1 to 88 lbs, and Advantage Multi 110 containing imidacloprid 500mg and moxidectin 125mg in 5 ml tubes for dogs 88.1 to 110 lbs. For dogs over 110 lbs use the appropriate combination of Advantage Multi for dogs tubes. Advantage Multi for Cats is available in the following concentrations; Advantage Multi 5 containing imidacloprid 23mg and moxidectin 2.3mg in 0.23ml tubes for cats 2 to 5 lbs, Advantage Multi 9 containing imidacloprid 40mg and moxidectin 4mg in 0.4ml tubes for cats 5.1 to 9 lbs, and Advantage Multi 18 containing imidacloprid 80mg and moxidectin 8mg in 0.8ml tubes for cats 9.1 to 18 lbs. For cats over 18 lbs use the appropriate combination. Children should not come in contact with the application site for 30 minutes after application.

What is Advantage Multi:

Advantage Multi for Dogs and Advantage Multi for Cats contain a combination of insecticide (imidacloprid) and endectocide (moxidectin) used for the prevention of heartworm disease and the treatment and control of flea infestations, hookworms, roundworms and whipworms in dogs and for the prevention of heartworm disease and the treatment and control of flea infestations, roundworms, hookworms, and ear mites in cats. Advantage Multi for Cats is now the first and only product indicated to kill adult fleas, treat flea infestations and prevent heartworm disease in ferrets.

What should I discuss with my veterinarian before applying Advantage Multi for Dogs and Cats:

Tell your veterinarian if your pet is breeding, pregnant or lactating since safe use of this product in these animals has not been determined. Do not use in animals allergic to Advantage Multi or either of the individual ingredients, imidacloprid (Advantage, K9 Advantix) or moxidectin (ProHeart).

How should this medication be used:

Advantage Multi is applied topically to the skin. It is not given by mouth. Follow the manufacturer's directions for application. Do not apply to irritated skin. Apply each dose once a month, every 30 days. If you do not understand the directions, or if you have difficulty applying the medication, contact your pharmacist or veterinarian. Store Advantage Multi for Cats at temperatures between 39° F and 86° F, avoiding excess heat or cold.

What happens if I miss giving a dose:

Apply the missed dose as soon as you remember. If it is almost time to apply the next dose, skip the missed dose and apply the next dose as directed. Do not apply 2 doses at once.

What happens if I overdose the pet:

Seek emergency veterinary medical treatment. Symptoms of overdose may include depression, increased salivation, tremors, or incoordination.

What should I avoid when applying Advantage Multi for Dogs and Cats:

Always follow the dosage instructions provided by your veterinarian. Do not use in dogs under 7 weeks of age or less than 3 lbs. Do not use in cats under 9 weeks of age or less than 2 lbs. Do not use Advantage Multi for Cats in ferrets under 2 lbs. Do not use on animals that are sick, debilitated, or underweight. Do not use Advantage Multi for Dogs on a cat. Do not use Advantage Multi for Cats on a dog. Do not allow any animal to lick the application site for 30 minutes. Separation of treated animals may be necessary. Children should not come in contact with the application site for 30 minutes after application. Advantage Multi can cause eye irritation and be harmful if swallowed. Wash hands thoroughly with soap and water after handling.

What are the possible side effects of Advantage Multi Dogs and Cats:

If any of the following serious side effects occur, stop using Advantage Multi and seek emergency veterinary medical attention; an allergic reaction (facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma). Contact your veterinarian if your dog shows scratching, rubbing, licking the application site; lethargy, decreased appetite, or hyperactivity. Contact your veterinarian if your cat shows lethargy and prolonged periods of sleep; behavioral changes including agitation, excessive grooming, hiding, pacing, etc.; discomfort at the application site (rubbing, scratching, etc.); increased salivation within 1 hour of treatment; increased drinking; or coughing. A medicinal odor and residue at the application site may also be seen. If the dog or cat ingests the product or licks the application site, serious adverse effects may occur including depression, salivation, incoordination, panting and tremors. Hair may appear stiff, matted oily, or damp after application. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.

What other drugs will affect Advantage Multi for Dogs and Cats:

Talk to your veterinarian or pharmacist regarding any other medications, including vitamins and supplements, and other flea and tick products your pet is using.

How to Use
Directions:
  • Advantage Multi for Dogs and Advantage Multi for Cats are prescription medications used for the prevention of heartworm disease.
  • Advantage Multi for Dogs is used in dogs for the treatment and control of flea infestation, hookworms, roundworms, and whipworms.
  • Advantage Multi for Cats is used in cats for the treatment and control of flea infestation, roundworms, hookworms, and ear mites.
  • Advantage Multi for Cats is also the first and only approved product to kill adult fleas, treat flea infestations and prevent heartworm disease in ferrets.
Tip:

For the first 30 minutes after application ensure that dogs and cats cannot lick the product from the application sites. Separate treated pets from one another and from other pets to reduce the risk of accidental ingestion. Wash hands with soap and water after handling. Do not let children touch the treated pet's skin for at least 30 minutes after applying the product. Do not get these products in the pet's mouth or eyes.

Dosage:
Dogs/Puppies: (7 weeks of age or older)
Weight
Dosage
3-9 lbs
While your dog is standing, apply Advantage Multi-9 for Dogs topically by parting the hair on the back of the dog between the shoulder blades until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. Apply each dose once, every 30 days
9.1-20 lbs
While your dog is standing, apply Advantage Multi-20 for Dogs topically by parting the hair on the back of the dog between the shoulder blades until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. Apply each dose once, every 30 days
20.1-55 lbs
While your dog is standing, apply Advantage Multi-55 for Dogs topically by parting the hair on the back of the dog between the shoulder blades until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Apply each dose once, every 30 days
55.1-88 lbs
While your dog is standing, apply Advantage Multi-88 for Dogs topically by parting the hair on the back of the dog between the shoulder blades until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Apply each dose once, every 30 days
88.1-110 lbs*
While your dog is standing, apply Advantage Multi-110 for Dogs topically by parting the hair on the back of the dog between the shoulder blades until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Apply each dose once, every 30 days
Cats/Kittens: (9 weeks of age or older)
Weight
Dosage
2-5 lbs
Apply Advantage Multi-5 for Cats topically by parting the hair on the back of the cat's neck at the base of the head until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift the tube away from the skin before releasing pressure on the tube. Apply each dose once, every 30 days
5.1-9 lbs
Apply Advantage Multi-9 for Cats topically by parting the hair on the back of the cat's neck at the base of the head until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift the tube away from the skin before releasing pressure on the tube. Apply each dose once, every 30 days
9.1-18 lbs**
Apply Advantage Multi-18 for Cats topically by parting the hair on the back of the cat's neck at the base of the head until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift the tube away from the skin before releasing pressure on the tube. Apply each dose once, every 30 days
Ferrets:
Weight
Dosage
2-4.4 lbs
Apply Advantage Multi-9 for Cats topically by parting the hair on the back of the ferret's neck at the base of the head until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift the tube away from the skin before releasing pressure on the tube. Apply each dose once, every 30 days
Horses:
Do not use!
Storage:

Should be stored at room temperature between 39° F and 86° F, avoiding excess heat or cold.

*For dogs over 110 lbs use the appropriate combination.

**For cats over 18 lbs use the appropriate combination.

Ingredients
Advantage Multi 9 for Dogs 3-9 lbs:
Active Ingredients
Amount
Imidacloprid
40 mg
Moxidectin
10 mg
Advantage Multi 20 for Dogs 9.1-20 lbs:
Active Ingredients
Amount
Imidacloprid
100 mg
Moxidectin
25 mg
Advantage Multi 55 for Dogs 20.1-55 lbs:
Active Ingredients
Amount
Imidacloprid
250 mg
Moxidectin
62.5 mg
Advantage Multi 88 for Dogs 55.1-88 lbs:
Active Ingredients
Amount
Imidacloprid
400 mg
Moxidectin
100 mg
Advantage Multi 110 for Dogs 88.1-110 lbs:
Active Ingredients
Amount
Imidacloprid
500 mg
Moxidectin
125 mg
Advantage Multi 5 for Cats 2-5 lbs:
Active Ingredients
Amount
Imidacloprid
23 mg
Moxidectin
2.3 mg
Advantage Multi 9 for Cats 5.1-9 lbs:
Active Ingredients
Amount
Imidacloprid
40 mg
Moxidectin
4 mg
Advantage Multi 18 for Cats 9.1-18 lbs:
Active Ingredients
Amount
Imidacloprid
80 mg
Moxidectin
8 mg
Customer Reviews
Advantage Multi is rated 4.1282 out of 5 by 234.
Rated 1 out of 5 by from Not for my pug I tried this medicine twice on my pug within a two year period. Both times my dog became lethargic and lost all control of his bladder functions. Never ever again.
Date published: 2016-04-20
Rated 5 out of 5 by from Great place to buy your pet meds 100% satisfied shiped very quick will definitely buy again
Date published: 2016-03-26
Rated 5 out of 5 by from Works great in Florida I've been using this product for one year now on my cat. I couldn't be happier, not one bug on him. He goes out in my yard daily.
Date published: 2016-03-05
Rated 4 out of 5 by from Great product I bought this a week and something ago, to start with in February's monthly preventative. We have two dogs, but one was completely out of preventative while the other was not (ironically, they are actually in the same size range for this medicine, but one is on the lower end and the other is on the higher end (28 pound smooth fox terrier mix, and a 55 pound labradoodle). I will later be ordering it for the smaller one, as she will run out of her (now discontinued) medicine in two months. Now, onto my thoughts. it arrived saturday of last week (thanks postal service for failing to deliver on suggested day of friday) and i put it on her that afternoon. i do like that this medicine has a 30 minute dry time (its nice that it is so short). The time came and went very quickly. i gave both of them a bath monday evening. So far so good with this medicine (though this is the first month and it is still winter here, so i dont think many fleas would be out....). Will be ordering it again for the smaller one. Same size category, different dog (glad that this company adds a label....) i wish it was a little cheaper, but coupon promos are nice, and its peace of mind knowing we wont deal with fleas (which could definitely be something to be more put to the test once spring starts hitting; as well as the real test being with the smaller dog and how she does with this medicine (she had a suspected adverse medicine reaction in july) as compared with other preventatives she has been on).
Date published: 2016-02-13
Rated 5 out of 5 by from Works well I have used this product on my 3 dogs for years. It's convenient to cover several issues with one monthly application. No adverse reactions ever. Price and delivery a plus
Date published: 2016-02-03
Rated 5 out of 5 by from Love it My cat tends to get ear mites in the winter and this is the only medication that keeps them at bay. This also keeps him free of everything except ticks and tapeworms so I really like to keep him treated with Advantage Multi so that I have very few worries about pests on my cat!
Date published: 2016-01-18
Rated 2 out of 5 by from Does NOT Keep the Fleas Away This medicine seems to be good for heartworms, but my dog has picked up fleas twice while on this medication, and I had to spend money treating him, when I already paid for the preventative. It's frustrating, and I'm now searching for new options.
Date published: 2016-01-07
Rated 5 out of 5 by from This product is great This is a great product. It worked great for two months then my puppy was starting to get fleas again. I took him to the vet and the vet gave me this flea medicine plus a one time dose of nexguard. That combination has worked wonders together. Now I only have him on the advantage Multi and he has no fleas.
Date published: 2015-12-04
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Q&A

Why do the prices differ after I add them to my cart, Advantage Multi for cat 9-18 lbs says $157 and change for a 12 pack, but after I add it to my cart, it says $174 and change, same with the Seresto collars, for cats, say $47+...and $52+ respectively. 

Asked by: Kim L
Within your cart you must add the discount code provided which right now would be "TOP10" Once the discount code has been entered, click apply. The price should reflect the discount total.
Answered by: Pharmacy Manager
Date published: 2016-03-14

Which one is safe for ferretts?

Asked by: Nichole
Advantage Multi can be used on ferrets weighing at least 2 pounds. Consult your veterinarian for the appropriate choice for your pet.
Answered by: Lisa M
Date published: 2016-03-09

Does advantage multi kill whip worms in cats

I need to know if cats get whip worms and if so does advantage multi kill them
Asked by: Eva
How many doses come in one box of this product
Answered by: Craig
Date published: 2016-03-02

can i combine anything with this to prevent ticks?

can i use frontline or seresto with advantage multi to prevent ticks aswell? our state gets lots of ticks
Asked by: salgal219
You may use other products to control ticks with Advantage Multi, but you may be "double dosing" on flea control depending upon the product you choose. I recommend the Preventic Collar, which only does ticks and will last 3 months. You just have to make sure the collar is in close contact with the skin, not loose around the neck, and about half way through the 3 months, take the collar off and scrape the inside to remove dirt and oil build-up to get back down to fresh collar.
Answered by: SuzyCVT
Date published: 2015-09-14

do i need a vet prescription to order Advantage Multi for my cats ?

Asked by: Joseph
yes
Answered by: Stephanie Duesler, Pharm. D, MBA
Date published: 2016-04-25

how long after application can dog go swimming ?

its summer and he loves going in the pool like 10 times a day or more in our backyard fenced hard to keep him out
Asked by: butch
Please wait at least 24 hours after application.
Answered by: Stephanie Duesler, Pharm. D, MBA
Date published: 2015-09-08

Ingesting Advantage Multi

I know the product is to be applied at the base of the neck where the cat will not be able to lick it. But cats are clever, they squirm, etc. and they may find a way to lick it. Please tell me how harmful it would be if a cat ingested all or part of the product. This question is for everyone but more for the manufacturer, vets, pharmacists, etc. Thank you.
Asked by: Anonymous
Ingestion of all of the product that has recently been applied may cause some stomach upset, but since the product does spread fairly rapidly (within 12 hours) after application, and treats intestinal worms in cats because they groom themselves and ingest the product, I wouldn't be too concerned.
Answered by: SuzyCVT
Date published: 2015-07-12

do i need to use a heart worm medicine with advantage multi? tilti

Asked by: Anonymous
No, advantage multi provides heartworm protection when used correctly.
Answered by: Stephanie Duesler, Pharm. D, MBA
Date published: 2015-05-28
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