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Monthly spot-on flea & tick treatment, kills fleas on contact with bioactivation technology.
 
  • New technology for flea control
  • Kills fleas, flea eggs & larvae
  • Kills 4 tick species that may transmit disease
  • Quick-drying, fragrance free & waterproof
  •  
     
     

    Activyl Tick Plus

     
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    Starts at $83.69 Ships in one business day or less
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      Product Info   How to use   Ingredients   Customer Reviews   Q & A  

    What is Activyl Tick Plus?

    Activyl Tick Plus is a monthly spot-on flea and tick treatment that contains an innovative new ingredient called indoxacarb to kills fleas, while also containing permethrin to control ticks and reduce the risk of disease. Activyl is fully activated when a flea lands on your pet and is killed using the flea's own enzymes. This brand-new technology is called bioactivation. Activyl Tick Plus is only for dogs and kills ticks, adult fleas, flea eggs and larvae; thereby, breaking the flea's lifecycle.

    Find Activyl Tick Plus for Dogs at 1-800-PetMeds
    For: Dogs/Puppies (8 weeks or older)
     
    Benefits:
    New technology for flea control
    Kills fleas, flea eggs and larvae
    Kills 4 tick species that may transmit disease
    Breaks flea's lifecycle
    Quick-drying and fragrance free
    Waterproof even after bathing

    How it works:
    Activyl works to break the flea's lifecycle by killing not only adult fleas, but also flea eggs and larvae, which reduces the chances of your pet becoming reinfested by fleas. The ingredients are spread through your dog's skin and coat, and when a flea lands on your pet, it takes up the active ingredient of Activyl Tick Plus and causes the enzymes in the flea to change. Activyl Tick Plus then reaches it's full active form and the flea becomes paralyzed and unable to feed. This process is called bioactivation — the newest technology in flea control. In addition, Activyl Tick Plus is waterproof, quick-drying, and fragrance free. As a bonus, Activyl Tick Plus also contains permethrin, which provides a broad-spectrum tick protection and kills four major tick species, which reduces the risk of your dog contracting a deadly tick-borne disease.

    Cautions:
    Do not use Activyl Tick Plus on cats, or allow your cat to lick or groom a dog treated with Activyl Tick Plus. Do not use on dogs or puppies under 8 weeks of age or under 4 lbs. Certain medications may interact with pesticides. If signs of sensitivity occur, contact your veterinarian immediately.


    More Information:
    Brand Name
    Activyl Tick Plus
    Generic Name
    Indoxacarb, Permethrin

    What is Activyl Tick Plus used for: Activyl Tick Plus is a monthly flea and tick treatment for dogs and puppies 8 weeks of age or older and over 4 lbs. It combines indoxacarb to kill fleas, flea eggs, and larvae to stop the flea's lifecycle, and permethrin for tick protection. The ingredient indoxacarb is a new innovative way to kill fleas by using the flea's own enzyme to activate Activyl Tick Plus to its full potential.

    Availability of Activyl Tick Plus: Activyl Tick Plus is a non-prescription (OTC) product.

    How Activyl Tick Plus should be used: Use Activyl Tick Plus on dogs or puppies 8 weeks of age or older, and over 5 lbs. It is available as 0.51 ml applicators for dogs 4.1-11 lbs, 1.0 ml applicators for dogs 11.1-22 lbs, 2.0 ml applicators for dogs 22.1-44 lbs, 4.0 ml applicators for dogs 44.1-88 lbs and 6.0 ml applicators for dogs 88.1-132 lbs.

    To use Activyl Tick Plus: Hold the applicator in an upright position away from your face and snap the tip by bending it and folding it back on itself. Part the hair and place the applicator tip against the skin on the base of the skull. Applying Activyl at the base of the skull will help prevent your pet from licking the product. Squeeze the applicator firmly and apply the entire contents directly to the skin (for smaller dogs). Do not allow Activyl to run off and do not have contact with the treated area until it is completely dry. Reapply Activyl every 30 days.
    For larger dogs: Start applying the contents between the shoulder blades working your way down to the tail while applying Activyl in 2-3 spots along the way. Make sure you thoroughly part the hair on each spot so the applicator touches the skin and not just the fur.

    What are the side effects of Activyl Tick Plus: Individual sensitivities while rare, may occur after using any pesticide product. Do not use on cats, since it may be fatal.

    What special precautions are there: Do not use on pregnant or lactating females. Do not use on puppies under 8 weeks of age or under 4 lbs. Do not allow children to apply product. Use the entire contents on each dog and do not split one tube between pets. Weigh your dog to ensure you are applying the right dose formulated for the weight of your pet. Consult your vet before using on debilitated, aged, or medicated pets. Do not use on pets intended for breeding, pregnant or nursing.

    Causes substantial but temporary eye injury. Harmful if swallowed or absorbed through skin. Do not get in eyes or on clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet.

    If in eyes: Hold eyes open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing. Call a physician if irritation persists.

    If on skin: Take off contaminated clothing. Rinse skin immediately with plenty of water for 15-20 minutes. Call a poison control center or doctor for treatment advice.

    If swallowed: Call a poison control center or a doctor for treatment advice. Have a person sip a glass of water if able to swallow. Do not induce vomiting unless told to by a doctor or poison control center. Do not give anything by mouth to an unconscious person.

    In the event of overdose: Contact your veterinarian or veterinary emergency room.

    How should I store Activyl Tick Plus: Do not remove tube from pack until ready to use. Store in a cool (below 77°F) dry place inaccessible to children and pets. Do not refrigerate and protect from direct sunlight.

    Directions:

    Hold the applicator in an upright position away from your face and snap the tip by bending it and folding it back on itself.
    Part the hair and place the applicator tip against the skin on the base of the skull. Applying Activyl Tick PLUS at the base of the skull will help prevent your pet from licking the product.
    Squeeze the applicator firmly and apply the entire contents directly to the skin.
    Do not allow Activyl Tick PLUS to run off and do not have contact with the treated area until it is completely dry.
    Reapply Activyl every 30 days.
    For Larger Dogs: Start applying the contents between the shoulder blades working your way down to the tail while applying Activyl Tick PLUS in 2-3 spots along the way. Make sure you thoroughly part the hair on each spot so the applicator touches the skin and not just the fur.
    Tip: Wait until the application site is fully dry (usually 24 hours) before bathing your pet. Also, allow 24 hours before letting your dog go swimming.
    Dosage:
    Pet Weight Dosage
    Dogs/Puppies:
    (over 8 weeks of age)
    4.1-11 lbs Apply contents of 1 applicator once a month (0.51 ml/0.02 fl oz)
    11.1-22 lbs Apply contents of 1 applicator once a month (1.0 ml/0.03 fl oz)
    22.1-44 lbs Apply contents of 1 applicator once a month (2.0 ml/0.07 fl oz)
    44.1-88 lbs Apply contents of 1 applicator once a month (4.0 ml/0.14 fl oz)
    88.1-132 lbs Apply contents of 1 applicator once a month (6.0 ml/0.20 fl oz)
    Cats & Kittens:
    Horses:
    Storage: Should be stored at room temperature.
    Activyl Tick Plus 4.1-11 lbs:
    Active ingredients (per 0.51 ml/0.02 fl oz applicator) Amount
    Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate 13.01%
    Permethrin: 3-(phenoxybenzyl)-methyl-() cis, trans-3-(2,2-dichloroethenyl)-2,2-Dimethylcyclopropanecarboxyl 42.50%
    Other Ingredients 44.49%

    Activyl Tick Plus 11.1-22 lbs:
    Active ingredients (per 1.0 ml/0.03 fl oz applicator) Amount
    Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate 13.01%
    Permethrin: 3-(phenoxybenzyl)-methyl-() cis, trans-3-(2,2-dichloroethenyl)-2,2-Dimethylcyclopropanecarboxyl 42.50%
    Other Ingredients 44.49%

    Activyl Tick Plus 22.1-44 lbs:
    Active ingredients (per 2.0 ml/0.07 fl oz applicator) Amount
    Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate 13.01%
    Permethrin: 3-(phenoxybenzyl)-methyl-() cis, trans-3-(2,2-dichloroethenyl)-2,2-Dimethylcyclopropanecarboxyl 42.50%
    Other Ingredients 44.49%

    Activyl Tick Plus 44.1-88 lbs:
    Active ingredients (per 4.0 ml/0.14 fl oz applicator) Amount
    Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate 13.01%
    Permethrin: 3-(phenoxybenzyl)-methyl-() cis, trans-3-(2,2-dichloroethenyl)-2,2-Dimethylcyclopropanecarboxyl 42.50%
    Other Ingredients 44.49%

    Activyl Tick Plus 88.1-132 lbs:
    Active ingredients (per 6.0 ml/0.20 fl oz applicator) Amount
    Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate 13.01%
    Permethrin: 3-(phenoxybenzyl)-methyl-() cis, trans-3-(2,2-dichloroethenyl)-2,2-Dimethylcyclopropanecarboxyl 42.50%
    Other Ingredients 44.49%
    Activyl Tick Plus 2.6 5 26 26
    doesn't work my vet told me this is what she was on as a puppy when she looked at her old vet papers, and she said this was the best so i bought a six pack on 1800 pet meds and used it twice and i always check for ticks here and there and i found 20 in two weeks!! my dog attracts them so that is why i started prevention, and this did not work, then we tried frontline, didn't work, then we looked at her adoption papers and saw she was on advantix at first, tried that , and guess what? after 7 months, of testing kinds, finally something worked. i was dissapointed, my vet lied and i wasted 90$! 03/03/2015
    Overall: wonderful My dog has never gone one summer without fleas, even with consistent usage of Advantix and Comfortis. However, with Activyl, I'm so happy to say she is flea-free for the first summer ever in the 5 years I've had her. However, I did deduct a star because I've found 2 ticks on her. It was no big deal; I removed them quickly; however, she has never had a tick prior to using this, so suffice it to say, the tick prevention may not be very effective. Overall though, with only 2 ticks found, I'm more than happy with Activyl. 09/26/2014
    Amazing for fleas I've used many products in the past: Frontline, Advantix, Seresto...but nothing has worked as well as Activyl Tick Plus. Frontline and Advantix don't seem to work anymore against fleas (did they change the formula?)...and my dogs HATED wearing the Seresto collar. My vet switched to Activyl at the beginning of this year and the results have been great! I haven't seen 1 flea (or tick) all year. Activyl does leave a wet spot after application, but I simply wash the spots with a damp cloth and brush it out after it dries (at my vet's recommendation). If fleas are an issue in your area, I'd definitely recommend giving Activyl Tick Plus a try. 09/02/2014
    Brittany Spaniel I've been using Actyvil Tick Plus on my Brittany (spaniel) since we've had her - 7 months. APPLICATION I am very careful to apply it exactly 4 weeks as directed. If needed, I bathe my dog the Saturday before, then apply the medicine on Wednesday, and then do not bathe her again until the following Saturday. I have to bathe her that following Saturday usually to remove the greasy spot. PROS: --> No fleas! We haven't had a flea. We even visited someone who had fleas, and returned back without a single flea on her and I haven't seen one in my house. --> OK with repelling ticks We went camping one weekend in June - real camping in a tent, and she didn't get a single tick or flea the entire time. We checked her thinking she would have something, but she was clean. I have only seen a single tick on her and that was after walking in some particularly heavy undergrowth near a lake. The tick had already bitten her and I had to remove it. I docked 1 star for effectiveness, but I still think the performance of the product is good. CONS --> Greasiness As stated by others, it does leave a greasy spot. It's not terrible with my dog's fur, and I'm usually bothered by that type of thing. It does feel sort of gross if you touch that area. Granted, brittany spaniels have a single coat of fur (and no under coat like german shepherds or goldens), so this may account for the difference in the greasiness. For me, it does go away by itself, mostly if she rolls around in dirt playing the dirt sort of 'sticks' to it (it looks gross since she's mostly white dog) and then the greasiness sort of dissipates away. It will go away also with puppy shampoo and water. I usually do this 2 days after application. It's even been as simple for me before as putting some puppy shampoo on a rag and just lathering the area behind her shoulders then rinsing with water - if I don't have time for a complete bath. When my vet recommended this to us - she did say the most common complaint was the greasiness. --> Temporary itchiness It also does seem to make my dog itch a little bit. We really only notice it on the day of application, she'll occasionally stop and scratch - but it doesn't seem to be significantly bothering, and if she had fleas I think she'd be scratching a lot more. --> Price Compared to other topical flea and tick medicines on the market, this does seem to be one of the more expensive. I haven't had experience with other topical to know if the price vs. effectiveness is worth it and cannot comment on that. All in all I'd say it's a product that worth trying. 08/08/2014
    Great product I have 3 dogs on this product and love it. The main reason I started it was my Bischon has a problem with flies. The vet started me on this and we have had no fleas for almost a year. He does get a tick once in awhile by his ear same with my Blue healer and Australian Shepard but one once in a month isn't nothing to 5-10 I was getting off of them in a days time. I will keeping using this product as long as I can. 08/02/2014
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    8 Questions · 12 Answers

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    I need to be careful what I use?
    2 months ago
    by
    Livy
    Answer this question
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    Answer: 
    Please consult with your vet in regards to using a flea and tick medication due to your furry pal's medical condition.
    2 months ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    6 months ago
    by
    Anonymous
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    Answer: 
    never, thi stuff dose not work, i would use k9 advantix 2 from now on.
    6 months ago
    by
    Juliecanry2345
    MA
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    Answer: 
    Thank you for your question. Activyl takes about 12 hours to kill 99% of fleas and ticks.
    6 months ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    1 year, 1 month ago
    by
    Kat
    Florida
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    Answer: 
    Please check with your veterinarian, thanks for your question.
    1 year, 1 month ago
    by
    Marty, Pharm. D.
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    This topical leaves a huge greasy mark on her that she then tries to rub off on the carpet, the furniture, etc. How long after applying can I give her a bath and use shampoo on her? Will the shampoo remove the medication?
    1 year, 1 month ago
    by
    Anonymous
    Raleigh, NC
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    Answer: 
    My groomer told me that you should wait for at least 3 days before you bathe your dog, and most importantly, make sure that you use a soap free shampoo, otherwise you'll remove the medication.
    8 months ago
    by
    nytn888
    Tennessee
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    Answer: 
    Thank you for your question. We suggest waiting 36-48 hours after application for a bath. The shampoo must be soap free to ensure that it does not remove flea and tick topicals.
    1 year, 1 month ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    1 year, 7 months ago
    by
    Anonymous
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    Answer: 
    Yes but Petsmed contacts the doctor for you.
    1 year, 4 months ago
    by
    Kit
    Jacksonville Florida
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    Answer: 
    This is an over the counter product and no prescription is required.
    1 year, 7 months ago
    by
    Chris H, PetMedPro
    Florida
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    • 2015-04-12T07:35:43.157-05:00
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    This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
    Note: Any trademarks are the property of their respective companies.
     
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